Janice Froehlich

  • 2543 Citations
  • 29 h-Index
1976 …2019

Research output per year

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Publications

  • 2543 Citations
  • 29 h-Index
  • 60 Article
  • 2 Chapter
  • 2 Review article
2019

Dual therapy for alcohol use disorders: Combining naltrexone with other medications

Froehlich, J., Nicholson, E. & Dilley, J., Jan 1 2019, Neuroscience of Alcohol: Mechanisms and Treatment. Elsevier, p. 653-660 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Alcohol Drinking and Blood Alcohol Concentration Revisited

Dilley, J. E., Nicholson, E. R., Fischer, S. M., Zimmer, R. & Froehlich, J. C., Feb 1 2018, In : Alcoholism: Clinical and Experimental Research. 42, 2, p. 260-269 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Co-Administration of Low-Dose Naltrexone and Bupropion Reduces Alcohol Drinking in Alcohol-Preferring (P) Rats

Nicholson, E. R., Dilley, J. E. & Froehlich, J. C., Mar 2018, In : Alcoholism: Clinical and Experimental Research. 42, 3, p. 571-577 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

The Effects of Long-Term Varenicline Administration on Ethanol and Sucrose Seeking and Self-Administration in Male P Rats

Czachowski, C. L., Froehlich, J. C. & DeLory, M., Feb 1 2018, In : Alcoholism: Clinical and Experimental Research. 42, 2, p. 453-460 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Combination of Naltrexone + Varenicline Retards the Expression of a Genetic Predisposition Toward High Alcohol Drinking

Froehlich, J., Fischer, S. M., Nicholson, E. R., Dilley, J. E., Filosa, N. J., Smith, T. N. & Rademacher, L. C., 2017, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

6 Scopus citations

Prazosin Prevents Increased Anxiety Behavior That Occurs in Response to Stress During Alcohol Deprivations

Rasmussen, D. D., Kincaid, C. L. & Froehlich, J. C., Jan 1 2017, In : Alcohol and alcoholism (Oxford, Oxfordshire). 52, 1, p. 5-11 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats

Froehlich, J. C., Nicholson, E. R., Dilley, J. E., Filosa, N. J., Rademacher, L. C. & Smith, T. N., Aug 2017, In : Alcoholism: Clinical and Experimental Research. 41, 8, p. 1510-1517 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Combining Varenicline (Chantix) with Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in a Rodent Model of Alcoholism

Froehlich, J. C., Fischer, S. M., Dilley, J. E., Nicholson, E. R., Smith, T. N., Filosa, N. J. & Rademacher, L. C., Sep 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 9, p. 1961-1970 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2015
11 Scopus citations

Prazosin Reduces Alcohol Intake in an Animal Model of Alcohol Relapse

Froehlich, J. C., Hausauer, B., Fischer, S., Wise, B. & Rasmussen, D. D., Aug 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 8, p. 1538-1546 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Animal models for the study of alcoholism: Utility of selected lines

Froehlich, J. & Li, T. K., Jun 3 2014, Behavioral and Biochemical Issues in Substance Abuse. Taylor and Francis, p. 61-71 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

18 Scopus citations

The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats

Rasmussen, D. D., Alexander, L., Malone, J., Federoff, D. & Froehlich, J. C., Sep 1 2014, In : Alcohol. 48, 6, p. 543-549 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2013

Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone

Froehlich, J. C., Hausauer, B. J. & Rasmussen, D. D., Oct 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, 10, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Prazosin reduces alcohol drinking throughout prolonged treatment and blocks the initiation of drinking in rats selectively bred for high alcohol intake

Froehlich, J. C., Hausauer, B. J., Federoff, D. L., Fischer, S. M. & Rasmussen, D. D., Sep 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, 9, p. 1552-1560 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

Effects of Prazosin, an α1-Adrenergic Receptor Antagonist, on the Seeking and Intake of Alcohol and Sucrose in Alcohol-Preferring (P) Rats

Verplaetse, T. L., Rasmussen, D. D., Froehlich, J. C. & Czachowski, C. L., May 1 2012, In : Alcoholism: Clinical and Experimental Research. 36, 5, p. 881-886 6 p.

Research output: Contribution to journalArticle

33 Scopus citations
2011

Alcohol Induces Liver Neoplasia in a Novel Alcohol-Preferring Rat Model

Yip-Schneider, M. T., Doyle, C. J., Mckillop, I. H., Wentz, S. C., Brandon-Warner, E., Matos, J. M., Sandrasegaran, K., Saxena, R., Hennig, M. E., Wu, H., Waters, J. A., Klein, P. J., Froehlich, J. C. & Max Schmidt, C., Dec 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 12, p. 2216-2225 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Imaging of alcohol-induced dopamine release in rats:Preliminary findings with [11C]raclopride PET

Sullivan, J. M., Risacher, S. L., Normandin, M. D., Yoder, K. K., Froehlich, J. C. & Morris, E. D., Sep 1 2011, In : Synapse. 65, 9, p. 929-937 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2010

What aspects of human alcohol use disorders can be modeled using selectively bred rat lines

Froehlich, J. C., Jun 1 2010, In : Substance Use and Misuse. 45, 11, p. 1727-1741 15 p.

Research output: Contribution to journalArticle

8 Scopus citations
2009

Effects of forced alcohol drinking on alcohol-water choice in three pairs of rat lines selectively bred for differences in alcohol preference

Timberlake, W., Leffel, J. K., Chester, J. A. & Froehlich, J. C., Mar 1 2009, In : Alcohol. 43, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

The α1-adrenergic receptor antagonist, prazosin, reduces alcohol drinking in alcohol-preferring (P) rats

Rasmussen, D. D., Alexander, L. L., Raskind, M. A. & Froehlich, J. C., Feb 1 2009, In : Alcoholism: Clinical and Experimental Research. 33, 2, p. 264-272 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
2006

Decreased reward during acute alcohol withdrawal in rats selectively bred for low alcohol drinking

Chester, J. A., Rausch, E. J., June, H. L. & Froehlich, J. C., Apr 1 2006, In : Alcohol. 38, 3, p. 165-172 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2005
17 Scopus citations

NtPET: A new application of PET Imaging for characterizing the kinetics of endogenous neurotransmitter release

Morris, E. D., Yoder, K. K., Wang, C., Normandin, M. D., Zheng, Q. H., Mock, B., Muzic, R. F. & Froehlich, J. C., Jan 1 2005, In : Molecular Imaging. 4, 4, p. 473-489 17 p.

Research output: Contribution to journalArticle

40 Scopus citations
2004
32 Scopus citations

Effects of Stress on Alcohol Consumption in Rats Selectively Bred for High or Low Alcohol Drinking

Chester, J. A., Blose, A. M., Zweifel, M. & Froehlich, J. C., Mar 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

64 Scopus citations
44 Scopus citations

Pain Thresholds in Alcohol Preferring and Non-preferring Rats: Diurnal and Repeated Trial Line Differences

Kimpel, M. W., Brown, M. M. & Froehlich, J. C., Dec 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 12, p. 1921-1928 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Preclinical and clinical studies on naltrexone: What have they taught each other?

Froehlich, J., O'Malley, S., Hyytiä, P., Davidson, D. & Farren, C., Mar 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 3, p. 533-539 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
2002
28 Scopus citations
2001

Effects of acamprosate on sensitization to the locomotor-stimulant effects of alcohol in mice selectively bred for high and low alcohol preference

Chester, J. A., Grahame, N. J., Li, T. K., Lumeng, L. & Froehlich, J. C., Jan 1 2001, In : Behavioural Pharmacology. 12, 6-7, p. 535-543 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Induction of steady-state blood alcohol levels: Application to the study of within-session alcohol tolerance in rats

Froehlich, J. C., Stewart, R. B., Li, T. K., Mosemiller, A. K., McCullough, D. E., Ho, M. C. & Kisner, J. M., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 3, p. 370-376 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2000

Analysis of heritability of hormonal responses to alcohol in twins: Beta-endorphin as a potential biomarker of genetic risk for alcoholism

Froehlich, J. C., Zink, R. W., Li, T. K. & Christian, J. C., Mar 2000, In : Alcoholism: Clinical and Experimental Research. 24, 3, p. 265-277 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

Naltrexone and alcohol drinking in mice lacking β-endorphin by site-directed mutagenesis

Grahame, N. J., Mosemiller, A. K., Low, M. J. & Froehlich, J. C., Dec 1 2000, In : Pharmacology Biochemistry and Behavior. 67, 4, p. 759-766 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
1999

Naloxone retards the expression of a genetic predisposition toward alcohol drinking

Badia-Elder, N. E., Mosemiller, A. K., Elder, R. L. & Froehlich, J. C., Jul 13 1999, In : Psychopharmacology. 144, 3, p. 205-212 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The δ2-opioid receptor antagonist naltriben reduces motivated responding for ethanol

June, H. L., McCane, S. R., Zink, R. W., Portoghese, P. S., Li, T. K. & Froehlich, J. C., Dec 1 1999, In : Psychopharmacology. 147, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

64 Scopus citations
1998

Contribution of the opioid system to alcohol aversion and alcohol drinking behavior

Froehlich, J. C., Badia-Elder, N. E., Zink, R. W., McCullough, D. E. & Portoghese, P. S., 1998, In : Journal of Pharmacology and Experimental Therapeutics. 287, 1, p. 284-292 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Effect of Mu opioid receptor blockade on alcohol intake in rats bred for high alcohol drinking

Krishnan-Sarin, S., Wand, G. S., Li, X. W., Portoghese, P. S. & Froehlich, J. C., Mar 1 1998, In : Pharmacology Biochemistry and Behavior. 59, 3, p. 627-635 9 p.

Research output: Contribution to journalArticle

92 Scopus citations

Enhanced sensitivity of the nucleus accumbens proenkephalin system to alcohol in rats selectively bred for alcohol preference

Li, X. W., Li, T. K. & Froehlich, J. C., May 25 1998, In : Brain research. 794, 1, p. 35-47 13 p.

Research output: Contribution to journalArticle

60 Scopus citations
22 Scopus citations
1997

Adenylyl cyclase signal transduction and alcohol-induced sedation

Froehlich, J. C. & Wand, G. S., Dec 1 1997, In : Pharmacology Biochemistry and Behavior. 58, 4, p. 1021-1030 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Comparison of rats selectively bred for high and low ethanol intake in a forced-swim-test model of depression: Effects of desipramine

Godfrey, C. D., Froehlich, J. C., Stewart, R. B., Li, T. K. & Murphy, J. M., Oct 1997, In : Physiology and Behavior. 62, 4, p. 729-733 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Opioid peptides

Froehlich, J. C., Dec 1 1997, In : Alcohol Research and Health. 21, 2, p. 132-136 5 p.

Research output: Contribution to journalArticle

54 Scopus citations

Quantitative comparison of mu opioid receptor mRNA in selected CNS regions of alcohol naive rats selectively bred for high and low alcohol drinking

Gong, J., Li, X. W., Lai, Z., Froehlich, J. C. & Yu, L., May 9 1997, In : Neuroscience Letters. 227, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

17 Scopus citations
1996

Genetic differences in tolerance and sensitization to the sedative/hypnotic effects of alcohol

Kurtz, D. L., Stewart, R. B., Zweifel, M., Li, T. K. & Froehlich, J. C., Mar 1996, In : Pharmacology Biochemistry and Behavior. 53, 3, p. 585-591 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

The neurobiology of ethanol-opioid interactions in ethanol reinforcement

Froehlich, J. C. & Wand, G., 1996, In : Alcoholism: Clinical and Experimental Research. 20, 8 SUPPL., p. 181A-186A

Research output: Contribution to journalArticle

50 Scopus citations
1995

Genetic factors in alcohol self-administration

Froehlich, J. C., Jan 1 1995, In : Journal of Clinical Psychiatry. 56, 9, p. 15-23 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

The delta2-opioid receptor antagonist naltriben selectively attenuates alcohol intake in rats bred for alcohol preference

Krishnan-Sarin, S., Portoghese, P. S., Li, T. K. & Froehlich, J. C., Sep 1995, In : Pharmacology, Biochemistry and Behavior. 52, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

95 Scopus citations

The delta opioid receptor antagonist naltrindole attenuates both alcohol and saccharin intake in rats selectively bred for alcohol preference

Krishnan-Sarin, S., Jing, S. L., Kurtz, D. L., Zweifel, M., Portoghese, P. S., Li, T. K. & Froehlich, J. C., Jul 1995, In : Psychopharmacology. 120, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

121 Scopus citations