Janice Froehlich

  • 2555 Citations
  • 29 h-Index
1976 …2019

Research output per year

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Publications

  • 2555 Citations
  • 29 h-Index
  • 60 Article
  • 2 Chapter
  • 2 Review article
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Article

A Combination of Naltrexone + Varenicline Retards the Expression of a Genetic Predisposition Toward High Alcohol Drinking

Froehlich, J., Fischer, S. M., Nicholson, E. R., Dilley, J. E., Filosa, N. J., Smith, T. N. & Rademacher, L. C., 2017, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

6 Scopus citations
32 Scopus citations

Adenylyl cyclase signal transduction and alcohol-induced sedation

Froehlich, J. C. & Wand, G. S., Dec 1 1997, In : Pharmacology Biochemistry and Behavior. 58, 4, p. 1021-1030 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Alcohol Drinking and Blood Alcohol Concentration Revisited

Dilley, J. E., Nicholson, E. R., Fischer, S. M., Zimmer, R. & Froehlich, J. C., Feb 1 2018, In : Alcoholism: Clinical and Experimental Research. 42, 2, p. 260-269 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alcohol Induces Liver Neoplasia in a Novel Alcohol-Preferring Rat Model

Yip-Schneider, M. T., Doyle, C. J., Mckillop, I. H., Wentz, S. C., Brandon-Warner, E., Matos, J. M., Sandrasegaran, K., Saxena, R., Hennig, M. E., Wu, H., Waters, J. A., Klein, P. J., Froehlich, J. C. & Max Schmidt, C., Dec 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 12, p. 2216-2225 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Analysis of heritability of hormonal responses to alcohol in twins: Beta-endorphin as a potential biomarker of genetic risk for alcoholism

Froehlich, J. C., Zink, R. W., Li, T. K. & Christian, J. C., Mar 2000, In : Alcoholism: Clinical and Experimental Research. 24, 3, p. 265-277 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

Animal models for the study of alcoholism: Utility of selected lines

Froehlich, J. C. & Li, T. K., Apr 12 1991, In : Journal of Addictive Diseases. 10, 1-2, p. 61-71 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Co-Administration of Low-Dose Naltrexone and Bupropion Reduces Alcohol Drinking in Alcohol-Preferring (P) Rats

Nicholson, E. R., Dilley, J. E. & Froehlich, J. C., Mar 2018, In : Alcoholism: Clinical and Experimental Research. 42, 3, p. 571-577 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone

Froehlich, J. C., Hausauer, B. J. & Rasmussen, D. D., Oct 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, 10, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
20 Scopus citations

Combining Varenicline (Chantix) with Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in a Rodent Model of Alcoholism

Froehlich, J. C., Fischer, S. M., Dilley, J. E., Nicholson, E. R., Smith, T. N., Filosa, N. J. & Rademacher, L. C., Sep 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 9, p. 1961-1970 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Comparison of rats selectively bred for high and low ethanol intake in a forced-swim-test model of depression: Effects of desipramine

Godfrey, C. D., Froehlich, J. C., Stewart, R. B., Li, T. K. & Murphy, J. M., Oct 1997, In : Physiology and Behavior. 62, 4, p. 729-733 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Contribution of the opioid system to alcohol aversion and alcohol drinking behavior

Froehlich, J. C., Badia-Elder, N. E., Zink, R. W., McCullough, D. E. & Portoghese, P. S., 1998, In : Journal of Pharmacology and Experimental Therapeutics. 287, 1, p. 284-292 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Decreased reward during acute alcohol withdrawal in rats selectively bred for low alcohol drinking

Chester, J. A., Rausch, E. J., June, H. L. & Froehlich, J. C., Apr 1 2006, In : Alcohol. 38, 3, p. 165-172 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Differences in response to the aversive properties of ethanol in rats selectively bred for oral ethanol preference

Froehlich, J. C., Harts, J., Lumeng, L. & Li, T. K., Sep 1988, In : Pharmacology, Biochemistry and Behavior. 31, 1, p. 215-222 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

Differences in the hypothermic response to ethanol in rats selectively bred for oral ethanol preference and nonpreference

Stewart, R. B., Kurtz, D. L., Zweifel, M., Li, T. K. & Froehlich, J. C., Jun 1992, In : Psychopharmacology. 106, 2, p. 169-174 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effect of Mu opioid receptor blockade on alcohol intake in rats bred for high alcohol drinking

Krishnan-Sarin, S., Wand, G. S., Li, X. W., Portoghese, P. S. & Froehlich, J. C., Mar 1 1998, In : Pharmacology Biochemistry and Behavior. 59, 3, p. 627-635 9 p.

Research output: Contribution to journalArticle

92 Scopus citations

Effects of acamprosate on sensitization to the locomotor-stimulant effects of alcohol in mice selectively bred for high and low alcohol preference

Chester, J. A., Grahame, N. J., Li, T. K., Lumeng, L. & Froehlich, J. C., Jan 1 2001, In : Behavioural Pharmacology. 12, 6-7, p. 535-543 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
17 Scopus citations

Effects of forced alcohol drinking on alcohol-water choice in three pairs of rat lines selectively bred for differences in alcohol preference

Timberlake, W., Leffel, J. K., Chester, J. A. & Froehlich, J. C., Mar 2009, In : Alcohol. 43, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effects of Prazosin, an α1-Adrenergic Receptor Antagonist, on the Seeking and Intake of Alcohol and Sucrose in Alcohol-Preferring (P) Rats

Verplaetse, T. L., Rasmussen, D. D., Froehlich, J. C. & Czachowski, C. L., May 1 2012, In : Alcoholism: Clinical and Experimental Research. 36, 5, p. 881-886 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Effects of Stress on Alcohol Consumption in Rats Selectively Bred for High or Low Alcohol Drinking

Chester, J. A., Blose, A. M., Zweifel, M. & Froehlich, J. C., Mar 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Enhanced sensitivity of the nucleus accumbens proenkephalin system to alcohol in rats selectively bred for alcohol preference

Li, X. W., Li, T. K. & Froehlich, J. C., May 25 1998, In : Brain research. 794, 1, p. 35-47 13 p.

Research output: Contribution to journalArticle

60 Scopus citations
44 Scopus citations

Genetic differences in avoidance learning by Rattus norvegicus: escape/avoidance responding, sensitivity to electric shock, discrimination learning, and open-field behavior.

Brush, F. R., Baron, S., Froehlich, J. C., Ison, J. R., Pellegrino, L. J., Phillips, D. S., Sakellaris, P. C. & Williams, V. N., Mar 1985, In : Journal of comparative psychology (Washington, D.C. : 1983). 99, 1, p. 60-73 14 p.

Research output: Contribution to journalArticle

51 Scopus citations

Genetic differences in tolerance and sensitization to the sedative/hypnotic effects of alcohol

Kurtz, D. L., Stewart, R. B., Zweifel, M., Li, T. K. & Froehlich, J. C., Mar 1996, In : Pharmacology Biochemistry and Behavior. 53, 3, p. 585-591 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Genetic factors in alcohol self-administration

Froehlich, J. C., Jan 1 1995, In : Journal of Clinical Psychiatry. 56, 9, p. 15-23 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

Genetic selection for avoidance behavior in the rat

Brush, F. R., Froehlich, J. C. & Sakellaris, P. C., Jul 1 1979, In : Behavior Genetics. 9, 4, p. 309-316 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Imaging of alcohol-induced dopamine release in rats:Preliminary findings with [11C]raclopride PET

Sullivan, J. M., Risacher, S. L., Normandin, M. D., Yoder, K. K., Froehlich, J. C. & Morris, E. D., Sep 1 2011, In : Synapse. 65, 9, p. 929-937 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Importance of delta opioid receptors in maintaining high alcohol drinking

Froehlich, J. C., Zweifel, M., Harts, J., Lumeng, L. & Li, T. K., Apr 1991, In : Psychopharmacology. 103, 4, p. 467-472 6 p.

Research output: Contribution to journalArticle

178 Scopus citations

Induction of steady-state blood alcohol levels: Application to the study of within-session alcohol tolerance in rats

Froehlich, J. C., Stewart, R. B., Li, T. K., Mosemiller, A. K., McCullough, D. E., Ho, M. C. & Kisner, J. M., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 3, p. 370-376 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Interaction between the posterior pituitary and LHRH in the control of LH secretion

Froehlich, J. C., Neill, M. A. & Ben-Jonathan, N., 1985, In : Peptides. 6, SUPPL. 1, p. 127-131 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
28 Scopus citations
22 Scopus citations

Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference

Froehlich, J. C., Harts, J., Lumeng, L. & Li, T. K., Feb 1990, In : Pharmacology, Biochemistry and Behavior. 35, 2, p. 385-390 6 p.

Research output: Contribution to journalArticle

258 Scopus citations

Naloxone attenuation of voluntary alcohol consumption

Froehlich, J. C., Harts, J., Lumeng, L. & Li, T. K., Jan 1 1987, In : Alcohol and Alcoholism. SUPPL. 1, p. 333-337 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

Naloxone retards the expression of a genetic predisposition toward alcohol drinking

Badia-Elder, N. E., Mosemiller, A. K., Elder, R. L. & Froehlich, J. C., Jul 13 1999, In : Psychopharmacology. 144, 3, p. 205-212 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Naltrexone and alcohol drinking in mice lacking β-endorphin by site-directed mutagenesis

Grahame, N. J., Mosemiller, A. K., Low, M. J. & Froehlich, J. C., Dec 1 2000, In : Pharmacology Biochemistry and Behavior. 67, 4, p. 759-766 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

NtPET: A new application of PET Imaging for characterizing the kinetics of endogenous neurotransmitter release

Morris, E. D., Yoder, K. K., Wang, C., Normandin, M. D., Zheng, Q. H., Mock, B., Muzic, R. F. & Froehlich, J. C., Jan 1 2005, In : Molecular Imaging. 4, 4, p. 473-489 17 p.

Research output: Contribution to journalArticle

43 Scopus citations

Opioid Involvement in Alcohol Drinking

FROEHLICH, JANICE. C. & LI, T. K., Oct 1994, In : Annals of the New York Academy of Sciences. 739, 1, p. 156-167 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Opioid peptides

Froehlich, J. C., Dec 1 1997, In : Alcohol Research and Health. 21, 2, p. 132-136 5 p.

Research output: Contribution to journalArticle

54 Scopus citations

Pain Thresholds in Alcohol Preferring and Non-preferring Rats: Diurnal and Repeated Trial Line Differences

Kimpel, M. W., Brown, M. M. & Froehlich, J. C., Dec 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 12, p. 1921-1928 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pharmacology of alcohol preference in rodents

Li, T. K., Lumeng, L., McBride, W. J., Murphy, J. M., Froehlich, J. C. & Morzorati, S., Mar 1 1988, In : Advances in Alcohol and Substance Abuse. 7, 3-4, p. 73-86 14 p.

Research output: Contribution to journalArticle

24 Scopus citations

Pituitary-adrenal activity and appetitive reinforcement

Randich, A., Froehlich, J. C., Fraley, S. M., Fjermestad, J. L. & Brush, F. R., Sep 1976, In : Physiological Psychology. 4, 3, p. 346-350 5 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Posterior pituitary involvement in the control of luteinizing hormone and prolactin secretion during the estrous cycle

Froehlich, J. C., Ben-Jonathan, N. & Neill, M. A., Jan 1 1984, In : Endocrinology. 114, 4, p. 1059-1064 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
11 Scopus citations

Prazosin Prevents Increased Anxiety Behavior That Occurs in Response to Stress During Alcohol Deprivations

Rasmussen, D. D., Kincaid, C. L. & Froehlich, J. C., Jan 1 2017, In : Alcohol and alcoholism (Oxford, Oxfordshire). 52, 1, p. 5-11 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Prazosin reduces alcohol drinking throughout prolonged treatment and blocks the initiation of drinking in rats selectively bred for high alcohol intake

Froehlich, J. C., Hausauer, B. J., Federoff, D. L., Fischer, S. M. & Rasmussen, D. D., Sep 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, 9, p. 1552-1560 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Prazosin Reduces Alcohol Intake in an Animal Model of Alcohol Relapse

Froehlich, J. C., Hausauer, B., Fischer, S., Wise, B. & Rasmussen, D. D., Aug 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 8, p. 1538-1546 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Preclinical and clinical studies on naltrexone: What have they taught each other?

Froehlich, J., O'Malley, S., Hyytiä, P., Davidson, D. & Farren, C., Mar 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 3, p. 533-539 7 p.

Research output: Contribution to journalArticle

30 Scopus citations