Jesus Dominguez

  • 1726 Citations
  • 24 h-Index
1974 …2018
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Publications 1974 2018

  • 1726 Citations
  • 24 h-Index
  • 72 Article
  • 1 Chapter
2018
3 Citations (Scopus)

Human extracellular microvesicles from renal tubules reverse kidney ischemia-reperfusion injury in rats

Dominguez, J. M., Dominguez, J., Xie, D. & Kelly, K., Jan 1 2018, In : PLoS One. 13, 8, p. e0202550

Research output: Contribution to journalArticle

Kidney Tubules
renal tubules
exosomes
ischemia
Reperfusion Injury
2017
16 Citations (Scopus)

Renal tubular cell-derived extracellular vesicles accelerate the recovery of established renal ischemia reperfusion injury

Dominguez, J., Liu, Y., Gao, H., Dominguez, J. M., Xie, D. & Kelly, K., Dec 1 2017, In : Journal of the American Society of Nephrology. 28, 12, p. 3533-3544 12 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Kidney
Ischemia
Extracellular Vesicles
Exosomes
2015
8 Citations (Scopus)

Improved structure and function in autosomal recessive polycystic rat kidneys with renal tubular cell therapy

Kelly, K., Zhang, J., Han, L., Kamocka, M., Miller, C., Gattone, V. H. & Dominguez, J., Jul 2 2015, In : PLoS One. 10, 7, e0131677.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
kidney cells
Cell- and Tissue-Based Therapy
Rats
kidneys
16 Citations (Scopus)

Renal C3 complement component: Feed forward to diabetic kidney disease

Kelly, K., Liu, Y., Zhang, J. & Dominguez, J., Mar 19 2015, In : American Journal of Nephrology. 41, 1, p. 48-56 9 p.

Research output: Contribution to journalArticle

Complement C3
Diabetic Nephropathies
Kidney
Complement Activation
Messenger RNA
3 Citations (Scopus)

Renal iron overload in rats with diabetic nephropathy

Dominguez, J., Liu, Y. & Kelly, K., 2015, In : Physiological Reports. 3, 12, e12654.

Research output: Contribution to journalArticle

Iron Overload
Diabetic Nephropathies
Kidney
Iron
Ischemia
2014
1 Citation (Scopus)

Oxidized low density lipoprotein (OX-LDL) induced arterial muscle contraction signaling mechanisms

Packer, C. S., Rice, A. E., Johnson, T. C., Pelaez, N. J., Temm, C. J., Potter, G. V., White, W. A., Roth, A. H., Dominguez, J. & Peterson, R. G., 2014, In : Open Hypertension Journal. 6, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

Muscle Contraction
Calcium
oxidized low density lipoprotein
Arteries
Hypertension
2013
12 Citations (Scopus)

Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways

Kelly, K., Liu, Y., Zhang, J., Goswami, C., Lin, H. & Dominguez, J., Aug 15 2013, In : Physiological Genomics. 45, 16, p. 710-719 10 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Chronic Renal Insufficiency
Kidney
Systems Biology
Fibrosis
7 Citations (Scopus)
Cell Transplantation
Diabetic Nephropathies
Kidney Transplantation
Chronic Kidney Failure
Kidney
2012
7 Citations (Scopus)
Cell Transplantation
Acute Kidney Injury
Kidney Transplantation
Chronic Kidney Failure
Kidney
2010
13 Citations (Scopus)
Amyloidogenic Proteins
Serum Amyloid A Protein
Cell- and Tissue-Based Therapy
Acute Kidney Injury
Blood Proteins
40 Citations (Scopus)
Diabetic Nephropathies
Acute Kidney Injury
Inflammation
Kidney
Chronic Renal Insufficiency
9 Citations (Scopus)

Treatment of the post-ischaemic inflammatory syndrome of diabetic nephropathy

Kelly, K. & Dominguez, J., Oct 2010, In : Nephrology Dialysis Transplantation. 25, 10, p. 3204-3212 9 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Mycophenolic Acid
Kidney
Ischemia
Inflammation
2009
12 Citations (Scopus)
Serum Amyloid A Protein
Acute-Phase Reaction
Acute-Phase Proteins
Kidney
Reperfusion Injury
34 Citations (Scopus)
Diabetic Nephropathies
Ischemia
Kidney
Chronic Kidney Failure
Blood Flow Velocity
2008
33 Citations (Scopus)

Anti-LOX-1 therapy in rats with diabetes and dyslipidemia: Ablation of renal vascular and epithelial manifestations

Dominguez, J., Mehta, J. L., Li, D., Wu, P., Kelly, K., Packer, C. S., Temm, C., Goss, E., Cheng, L., Zhang, S., Patterson, C. E., Hawes, J. W. & Peterson, R., Jan 2008, In : American Journal of Physiology - Renal Physiology. 294, 1

Research output: Contribution to journalArticle

Dyslipidemias
Blood Vessels
Kidney
Therapeutics
Intravenous Injections
47 Citations (Scopus)

LOX-1 and inflammation: A new mechanism for renal injury in obesity and diabetes

Kelly, K., Wu, P., Patterson, C. E., Temm, C. & Dominguez, J., May 2008, In : American Journal of Physiology - Renal Physiology. 294, 5

Research output: Contribution to journalArticle

Obesity
Inflammation
Kidney
Lipids
Wounds and Injuries
2007
36 Citations (Scopus)
Phenotype
Kidney
Inflammation
Fibrosis
Lipids
14 Citations (Scopus)

Microcirculation: Nexus of comorbidities in diabetes

Temm, C. & Dominguez, J., Aug 2007, In : American Journal of Physiology - Renal Physiology. 293, 2

Research output: Contribution to journalArticle

Microcirculation
Comorbidity
Kidney
Albumins
Fibrosis
2006
34 Citations (Scopus)

Renal injury: Similarities and differences in male and female rats with the metabolic syndrome

Dominguez, J., Wu, P., Hawes, J. W., Deeg, M., Walsh, J., Packer, S. C., Nagase, M., Temm, C., Goss, E. & Peterson, R., Jun 2006, In : Kidney International. 69, 11, p. 1969-1976 8 p.

Research output: Contribution to journalArticle

Kidney
Wounds and Injuries
Oxidants
Inflammation
Lipids
2005
14 Citations (Scopus)
Plasmapheresis
Multiple Myeloma
Acute Kidney Injury
Renal Insufficiency
Kidney
2002
24 Citations (Scopus)

Apheresis in cryoglobulinemia complicating hepatitis C and in other renal diseases

Dominguez, J. & Sha, E., 2002, In : Therapeutic Apheresis. 6, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Cryoglobulins
Cryoglobulinemia
Blood Component Removal
Hepatitis C
Kidney
8 Citations (Scopus)

Studies of renal injury IV: The GLUT1 gene protects renal cells from cyclosporine A toxicity

Dominguez, J., Soleimani, M. & Batiuk, T., 2002, In : Kidney International. 62, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Cyclosporine
Kidney
Wounds and Injuries
Glucose
Genes
2000
62 Citations (Scopus)

Studies of renal injury III: Lipid-induced nephropathy in type II diabetes

Dominguez, J., Tang, N., Xu, W., Evan, A., Siakotos, A. N., Agarwal, R., Walsh, J., Deeg, M., Pratt, J. H., March, K. L., Monnier, V. M., Weiss, M. F., Baynes, J. W. & Peterson, R., 2000, In : Kidney International. 57, 1, p. 92-104 13 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Kidney
Wounds and Injuries
Carbohydrates
Renal Insufficiency
1997
67 Citations (Scopus)

Overexpression of GLUT2 gene in renal proximal tubules of diabetic Zucker rats

Kamran, M., Peterson, R. G. & Dominguez, J., Jun 1997, In : Journal of the American Society of Nephrology. 8, 6, p. 943-948 6 p.

Research output: Contribution to journalArticle

Zucker Rats
Proximal Kidney Tubule
Glucose
Genes
Facilitative Glucose Transport Proteins
1996
11 Citations (Scopus)

Inhibition of glycosylation decreases Na+/H+ exchange activity, blocks NHE-3 transport to the membrane, and increases NHE-3 mRNA expression in LLC-PK1 cells

Soleimani, M., Singh, G., Bookstein, C., Rao, M. C., Chang, E. B. & Dominguez, J., Jun 1996, In : Journal of Laboratory and Clinical Medicine. 127, 6, p. 565-573 9 p.

Research output: Contribution to journalArticle

LLC-PK1 Cells
Glycosylation
Tunicamycin
Membranes
Messenger RNA
15 Citations (Scopus)

Studies of renal injury. I. Gentamicin toxicity and expression of basolateral transporters

Dominguez, J., Hale, C. C. & Qulali, M., 1996, In : American Journal of Physiology - Renal Physiology. 270, 2 PART 2

Research output: Contribution to journalArticle

Gentamicins
Kidney
Messenger RNA
Wounds and Injuries
Proteins
20 Citations (Scopus)

Studies of renal injury. II. Activation of the glucose transporter 1 (GLUT1) gene and glycolysis in LLC-PK1 cells under Ca2+ stress

Dominguez, J., Song, B., Liu-Chen, S., Qulali, M., Howard, R., Lee, C-H. & McAteer, J., Jul 15 1996, In : Journal of Clinical Investigation. 98, 2, p. 395-404 10 p.

Research output: Contribution to journalArticle

LLC-PK1 Cells
Facilitative Glucose Transport Proteins
Glycolysis
Kidney
Wounds and Injuries
1995
22 Citations (Scopus)

Long-term high osmolality activates Na+-H+ exchange and protein kinase C in aortic smooth muscle cells

Soleimani, M., Singh, G., Dominguez, J. & Howard, R. L., 1995, In : Circulation Research. 76, 4, p. 530-535 6 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Osmolar Concentration
Protein Kinase C
Sodium-Hydrogen Antiporter
Smooth Muscle Myocytes
1994
25 Citations (Scopus)

Gene expression of epithelial glucose transporters: The role of diabetes mellitus

Dominguez, J., Song, B., Maianu, L., Garvey, W. T. & Qulali, M., Nov 1994, In : Journal of the American Society of Nephrology. 5, 1 SUPPL.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Diabetes Mellitus
Gene Expression
Glucose
Proximal Kidney Tubule
90 Citations (Scopus)

Molecular adaptations of GLUT1 and GLUT2 in renal proximal tubules of diabetic rats

Dominguez, J., Camp, K., Maianu, L., Feister, H. & Garvey, W. T., Feb 1994, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 266, 2 35-2

Research output: Contribution to journalArticle

Proximal Kidney Tubule
Glucose
Hyperglycemia
Blood Glucose
Glucose Transporter Type 2
1993
142 Citations (Scopus)
Diabetic Cardiomyopathies
Insulin
Glucose
Streptozocin
3-O-Methylglucose
33 Citations (Scopus)

Muscle group-specific regulation of GLUT 4 glucose transporters in control, diabetic, and insulin-treated diabetic rats

Hardin, D. S., Dominguez, J. & Garvey, W. T., 1993, In : Metabolism: Clinical and Experimental. 42, 10, p. 1310-1315 6 p.

Research output: Contribution to journalArticle

Rectus Abdominis
Facilitative Glucose Transport Proteins
Quadriceps Muscle
Myocardium
Insulin
1992
38 Citations (Scopus)
Facilitative Glucose Transport Proteins
Glucose
Membranes
Microvilli
Western Blotting
4 Citations (Scopus)

Gp-regulated phosphoinositide hydrolysis in turkey and human erythrocytes exposed to fluoride ion: Relationship to calcium influx

English, D., Akard, L. P., Taylor, G. S., Rizzo, M. T., Dominguez, J. & Garcia, J. G. N., 1992, In : Journal of Laboratory and Clinical Medicine. 119, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Fluorides
Hydrolysis
Diglycerides
Erythrocytes
23 Citations (Scopus)

Na+-Ca2+ exchanger of rat proximal tubule: Gene expression and subcellular localization

Dominguez, J., Juhaszova, M., Kleiboeker, S. B., Hale, C. C. & Feister, H. A., Nov 1992, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 263, 5 32-5

Research output: Contribution to journalArticle

Proximal Kidney Tubule
Gene Expression
Sarcolemma
Proteins
Northern Blotting
43 Citations (Scopus)

Role of protein kinase C in the regulation of prostaglandin synthesis in human endothelium.

Garcia, J. G., Stasek, J., Natarajan, V., Patterson, C. E. & Dominguez, J., Mar 1992, In : American Journal of Respiratory Cell and Molecular Biology. 6, 3, p. 315-325 11 p.

Research output: Contribution to journalArticle

Protein Kinase C
Prostaglandins
Endothelium
Epoprostenol
Thrombin
12 Citations (Scopus)

The renal sodium-calcium exchanger

Dominguez, J., Juhaszova, M. & Feister, H. A., 1992, In : Journal of Laboratory and Clinical Medicine. 119, 6, p. 640-649 10 p.

Research output: Contribution to journalArticle

Sodium-Calcium Exchanger
Calcium
Kidney
Rats
Sodium
1991
16 Citations (Scopus)

Fluoride mobilizes intracellular calcium and promotes Ca2+ influx in rat proximal tubules

Dominguez, J., Garcia, J. G. N., Rothrock, J. K., English, D. & Mann, C., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 2 30-2

Research output: Contribution to journalArticle

Pertussis Toxin
Phosphatidylinositols
Fluorides
Aequorin
Hydrolysis
2 Citations (Scopus)

Inhibition of aldosterone production by pinacidil in vitro

Pratt, J. H., Rothrock, J. K. & Dominguez, J., Oct 1991, In : Hypertension. 18, 4, p. 529-534 6 p.

Research output: Contribution to journalArticle

Pinacidil
Aldosterone
Angiotensin II
Adrenocorticotropic Hormone
Corticotropin Receptors
3 Citations (Scopus)

Inhibitory effects of phospholipase D on chondrogenesis in vitro

Tsonis, P. A., Del Rio-Tsonis, K., Rothrock, J., Dominguez, J., English, D., Glade, K. & Goetinck, P. F., 1991, In : Experimental Cell Research. 195, 2, p. 551-555 5 p.

Research output: Contribution to journalArticle

Chondrogenesis
Phospholipase D
Phosphatidylinositol Phosphates
Phosphatidic Acids
Inositol Phosphates
13 Citations (Scopus)

Na+-Ca2+ exchange and Ca2+ depletion in rat proximal tubules

Dominguez, J., Mann, C., Rothrock, J. K. & Bhati, V., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 2 30-2

Research output: Contribution to journalArticle

Buffers
Aequorin
Proximal Kidney Tubule
Ouabain
Proteins
29 Citations (Scopus)
Sodium Fluoride
Guanine Nucleotides
Pertussis Toxin
Epoprostenol
Phosphatidylinositols
1990

Phosphate transport after acute changes in total NAD content in renal proximal tubules

Campbell, P. I., Abraham, M. I., Dominguez, J., McAteer, J. A. & Kempson, S. A., 1990, In : Proceedings of the Society for Experimental Biology and Medicine. 193, 4, p. 253-258 6 p.

Research output: Contribution to journalArticle

Proximal Kidney Tubule
NAD
Phosphates
Brushes
Microvilli
1989
43 Citations (Scopus)

Evidence that angiotensin-II and potassium collaborate to increase cytosolic calcium and stimulate the secretion of aldosterone

Pratt, J. H., Rothrock, J. K. & Dominguez, J., 1989, In : Endocrinology. 125, 5, p. 2463-2469 7 p.

Research output: Contribution to journalArticle

Aldosterone
Angiotensin II
Potassium
Calcium
Secretory Rate
19 Citations (Scopus)

Na+ electrochemical gradient and Na+-Ca2+ exchange in rat proximal tubule

Dominguez, J., Rothrock, J. K., Macias, W. L. & Price, J., 1989, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 257, 4

Research output: Contribution to journalArticle

Ouabain
Calcium
Thermodynamics
Cell Membrane
1988
5 Citations (Scopus)

Prostaglandin E2 is an inhibitor of adenylate cyclase in rabbit proximal tubule

Dominguez, J., Shuler, F., Olszowy, M. W., Brown, T. & Puschett, J. B., 1988, In : American Journal of Physiology - Cell Physiology. 254, 2

Research output: Contribution to journalArticle

Dinoprostone
Adenylyl Cyclases
Rabbits
Parathyroid Hormone
Chemical activation

Prostaglandin E2 is an inhibitor of adenylate cyclase in rabbit proximal tubule.

Dominguez, J., Shuler, F., Olszowy, M. W., Brown, T. & Puschett, J. B., Feb 1988, In : The American journal of physiology. 254, 2 Pt 1

Research output: Contribution to journalArticle

Dinoprostone
Rabbits
Parathyroid Hormone
Adenylyl Cyclases
Proximal Kidney Tubule
1987
22 Citations (Scopus)

Intracellular messenger for action of angiotensin II on fluid transport in rabbit proximal tubule

Dominguez, J., Snowdowne, K. W., Freudenrich, C. C., Brown, T. & Borle, A. B., 1987, American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 3 ed. Vol. 252.

Research output: Chapter in Book/Report/Conference proceedingChapter

Angiotensin II
Rabbits
Calcium
Adenylyl Cyclases
Aequorin
1986
10 Citations (Scopus)

Renal osteodystrophy in patients on hemodialysis for more than 10 years

Piraino, B. M., Rault, R., Dominguez, J. & Puschett, J. B., 1986, In : Mineral and Electrolyte Metabolism. 12, 5-6, p. 390-396 7 p.

Research output: Contribution to journalArticle

Chronic Kidney Disease-Mineral and Bone Disorder
Biopsy
Renal Dialysis
Bone and Bones
11 Citations (Scopus)

Spontaneous hypercalcemia in patients undergoing dialysis. Etiologic and therapeutic considerations

Piraino, B. M., Rault, R., Greenberg, A., Dominguez, J., Wallia, R., Houck, P., Segre, G. V., Chen, T., Foti, F. M. & Puschett, J. B., 1986, In : The American Journal of Medicine. 80, 4, p. 607-615 9 p.

Research output: Contribution to journalArticle

Hypercalcemia
Dialysis
Therapeutics
Chronic Kidney Disease-Mineral and Bone Disorder
Osteitis