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Jian-Ting Zhang

  • 4142 Citations
  • 39 h-Index
1989 …2018
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P-Glycoprotein Medicine & Life Sciences
ATP-Binding Cassette Transporters Medicine & Life Sciences
Multiple Drug Resistance Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Drug Resistance Medicine & Life Sciences
Membranes Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Fatty Acid Synthases Medicine & Life Sciences

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NIH Grants 1994 2016

Molecular targeting the translational control axis in Wnt/?-catenin signaling pathway

Zhang, J.

Project: Research project

Therapeutic targeting of stratifin structure and function

Zhang, J.

National Institutes of Health

7/1/10 → 5/31/16

Project: Research project

Apoptosis
Pancreatic Neoplasms
Radiation
Dimerization
Pharmaceutical Preparations

Targeting the amino terminal gate of human MRP1

Zhang, J.

National Institutes of Health

7/1/07 → 5/31/12

Project: Research project

Multiple Drug Resistance
ATP-Binding Cassette Transporters
Pharmaceutical Preparations
P-Glycoprotein
Neoplasms

Targeting the oligomerization of human ABCG2

Zhang, J.

National Institutes of Health

4/18/06 → 2/28/11

Project: Research project

Multiple Drug Resistance
ATP-Binding Cassette Transporters
Neoplasms
Drug Resistance
Pharmaceutical Preparations

Role of p170 in lung tumorigenesis

Zhang, J.

National Institutes of Health

9/30/03 → 6/30/09

Project: Research project

Carcinogenesis
Lung
Growth
Translational Peptide Chain Initiation
Eukaryotic Initiation Factors

Publications 1989 2018

1 Citation (Scopus)

Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation

Li, J., Qu, X., Tian, J., Zhang, J-T. & Cheng, J. X., Feb 1 2018, In : PLoS One. 13, 2, e0193318.

Research output: Contribution to journal › Article

gemcitabine
Esterification
esterification
adenocarcinoma
Adenocarcinoma

eIF3a: A new anticancer drug target in the eIF family

Yin, J. Y., Zhang, J-T., Zhang, W., Zhou, H. H. & Liu, Z. Q., Jan 1 2018, In : Cancer Letters. 412, p. 81-87 7 p.

Research output: Contribution to journal › Short survey

Physiological Phenomena
Proto-Oncogenes
Pathologic Processes
Pharmaceutical Preparations
Neoplasms
2 Citations (Scopus)

Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth

Li, X., Ma, H., Li, L., Chen, Y., Sun, X., Dong, Z., Liu, J. Y., Zhu, W. & Zhang, J-T., May 1 2018, In : Oncogene. 37, 18, p. 2469-2480 12 p.

Research output: Contribution to journal › Article

STAT3 Transcription Factor
src Homology Domains
Alkaloids
Heterografts
Transcriptional Activation
2 Citations (Scopus)

Small-molecule compounds targeting the STAT3 DNA-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis

Huang, W., Liu, Y., Wang, J., Yuan, X., Jin, H. W., Zhang, L. R., Zhang, J-T., Liu, Z. M. & Cui, J. R., Sep 5 2018, In : European Journal of Medicinal Chemistry. 157, p. 887-897 11 p.

Research output: Contribution to journal › Article

STAT3 Transcription Factor
Ovarian Neoplasms
Cisplatin
Cells
Apoptosis
6 Citations (Scopus)

Two decades of research in discovery of anticancer drugs targeting STAT3, how close are we?

Beebe, J. D., Liu, J. Y. & Zhang, J-T., Nov 1 2018, In : Pharmacology and Therapeutics. 191, p. 74-91 18 p.

Research output: Contribution to journal › Review article

STAT3 Transcription Factor
Drug Delivery Systems
Research
Biological Phenomena
Neoplasms