Projects per year
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- 2 Similar Profiles
P-Glycoprotein
Medicine & Life Sciences
ATP-Binding Cassette Transporters
Medicine & Life Sciences
Multiple Drug Resistance
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Drug Resistance
Medicine & Life Sciences
Membranes
Medicine & Life Sciences
Pharmaceutical Preparations
Medicine & Life Sciences
Fatty Acid Synthases
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
NIH Grants 1994 2016
Molecular targeting the translational control axis in Wnt/?-catenin signaling pathway
Project: Research project
Therapeutic targeting of stratifin structure and function
7/1/10 → 5/31/16
Project: Research project › Research Project
Apoptosis
Pancreatic Neoplasms
Radiation
Dimerization
Pharmaceutical Preparations
Targeting the amino terminal gate of human MRP1
7/1/07 → 5/31/12
Project: Research project › Research Project
Multiple Drug Resistance
ATP-Binding Cassette Transporters
Pharmaceutical Preparations
P-Glycoprotein
Neoplasms
Targeting the oligomerization of human ABCG2
4/18/06 → 2/28/11
Project: Research project › Research Project
Multiple Drug Resistance
ATP-Binding Cassette Transporters
Neoplasms
Drug Resistance
Pharmaceutical Preparations
Carcinogenesis
Lung
Growth
Translational Peptide Chain Initiation
Eukaryotic Initiation Factors
Publications 1989 2018
Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation
Li, J., Qu, X., Tian, J., Zhang, J-T. & Cheng, J. X., Feb 1 2018, In : PLoS One. 13, 2, e0193318.Research output: Contribution to journal › Article
gemcitabine
Esterification
esterification
adenocarcinoma
Adenocarcinoma
eIF3a: A new anticancer drug target in the eIF family
Yin, J. Y., Zhang, J-T., Zhang, W., Zhou, H. H. & Liu, Z. Q., Jan 1 2018, In : Cancer Letters. 412, p. 81-87 7 p.Research output: Contribution to journal › Short survey
Physiological Phenomena
Proto-Oncogenes
Pathologic Processes
Pharmaceutical Preparations
Neoplasms
1
Citations
Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth
Li, X., Ma, H., Li, L., Chen, Y., Sun, X., Dong, Z., Liu, J. Y., Zhu, W. & Zhang, J-T., May 1 2018, In : Oncogene. 37, 18, p. 2469-2480 12 p.Research output: Contribution to journal › Article
STAT3 Transcription Factor
src Homology Domains
Alkaloids
Heterografts
Transcriptional Activation
Small-molecule compounds targeting the STAT3 DNA-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis
Huang, W., Liu, Y., Wang, J., Yuan, X., Jin, H. W., Zhang, L. R., Zhang, J-T., Liu, Z. M. & Cui, J. R., Sep 5 2018, In : European Journal of Medicinal Chemistry. 157, p. 887-897 11 p.Research output: Contribution to journal › Article
STAT3 Transcription Factor
Cisplatin
Cells
Apoptosis
Molecules
Two decades of research in discovery of anticancer drugs targeting STAT3, how close are we?
Beebe, J. D., Liu, J. Y. & Zhang, J-T., Nov 1 2018, In : Pharmacology and Therapeutics. 191, p. 74-91 18 p.Research output: Contribution to journal › Review article
STAT3 Transcription Factor
Drug Delivery Systems
Research
Biological Phenomena
Neoplasms