Jian-Ting Zhang

  • 4035 Citations
  • 38 h-Index
1989 …2018
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  • 2 Similar Profiles
P-Glycoprotein Medicine & Life Sciences
ATP-Binding Cassette Transporters Medicine & Life Sciences
Multiple Drug Resistance Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Drug Resistance Medicine & Life Sciences
Membranes Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Fatty Acid Synthases Medicine & Life Sciences

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NIH Grants 1994 2016

Therapeutic targeting of stratifin structure and function

Zhang, J.

National Institutes of Health

7/1/105/31/16

Project: Research projectResearch Project

Apoptosis
Pancreatic Neoplasms
Radiation
Dimerization
Pharmaceutical Preparations

Targeting the amino terminal gate of human MRP1

Zhang, J.

National Institutes of Health

7/1/075/31/12

Project: Research projectResearch Project

Multiple Drug Resistance
ATP-Binding Cassette Transporters
Pharmaceutical Preparations
P-Glycoprotein
Neoplasms

Targeting the oligomerization of human ABCG2

Zhang, J.

National Institutes of Health

4/18/062/28/11

Project: Research projectResearch Project

Multiple Drug Resistance
ATP-Binding Cassette Transporters
Neoplasms
Drug Resistance
Pharmaceutical Preparations

Role of p170 in lung tumorigenesis

Zhang, J.

National Institutes of Health

9/30/036/30/09

Project: Research projectResearch Project

Carcinogenesis
Lung
Growth
Translational Peptide Chain Initiation
Eukaryotic Initiation Factors

Publications 1989 2018

Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation

Li, J., Qu, X., Tian, J., Zhang, J-T. & Cheng, J. X., Feb 1 2018, In : PLoS One. 13, 2, e0193318.

Research output: Contribution to journalArticle

gemcitabine
Esterification
esterification
adenocarcinoma
Adenocarcinoma

eIF3a: A new anticancer drug target in the eIF family

Yin, J. Y., Zhang, J-T., Zhang, W., Zhou, H. H. & Liu, Z. Q., Jan 1 2018, In : Cancer Letters. 412, p. 81-87 7 p.

Research output: Contribution to journalShort survey

Physiological Phenomena
Proto-Oncogenes
Pathologic Processes
Pharmaceutical Preparations
Neoplasms
1 Citations

Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth

Li, X., Ma, H., Li, L., Chen, Y., Sun, X., Dong, Z., Liu, J. Y., Zhu, W. & Zhang, J-T., May 1 2018, In : Oncogene. 37, 18, p. 2469-2480 12 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
src Homology Domains
Alkaloids
Heterografts
Transcriptional Activation

Small-molecule compounds targeting the STAT3 DNA-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis

Huang, W., Liu, Y., Wang, J., Yuan, X., Jin, H. W., Zhang, L. R., Zhang, J-T., Liu, Z. M. & Cui, J. R., Sep 5 2018, In : European Journal of Medicinal Chemistry. 157, p. 887-897 11 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Cisplatin
Cells
Apoptosis
Molecules

Two decades of research in discovery of anticancer drugs targeting STAT3, how close are we?

Beebe, J. D., Liu, J. Y. & Zhang, J-T., Nov 1 2018, In : Pharmacology and Therapeutics. 191, p. 74-91 18 p.

Research output: Contribution to journalReview article

STAT3 Transcription Factor
Drug Delivery Systems
Research
Biological Phenomena
Neoplasms