Jianjian Shi

  • 2219 Citations
  • 22 h-Index
19962020

Research output per year

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Publications

  • 2219 Citations
  • 22 h-Index
  • 28 Article
  • 8 Review article
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Article
1996

Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice

Mason, H. S., Ball, J. M., Shi, J. J., Jiang, X., Estes, M. K. & Arntzen, C. J., May 28 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 11, p. 5335-5340 6 p.

Research output: Contribution to journalArticle

446 Scopus citations
2003

Short- and Long-Term Effects of Growth Hormone (GH) Replacement on Protein Metabolism in GH-Deficient Adults

Shi, J., Sekhar, R. V., Balasubramanyam, A., Ellis, K., Reeds, P. J., Jahoor, F. & Sharma, M. D., Dec 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 12, p. 5827-5833 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2006

Physiologic growth hormone replacement improves fasting lipid kinetics in patients with HIV lipodystrophy syndrome

D'Amico, S., Shi, J., Sekhar, R. V., Jahoor, F., Ellis, K. J., Rehman, K., Willis, J., Maldonado, M. & Balasubramanyam, A., Jul 1 2006, In : American Journal of Clinical Nutrition. 84, 1, p. 204-211 8 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis

Zhang, Y. M., Bo, J., Taffet, G. E., Chang, J., Shi, J., Reddy, A. K., Michael, L. H., Schneider, M. D., Entman, M. L., Schwartz, R. J. & Wei, L., May 2006, In : FASEB Journal. 20, 7, p. 916-925 10 p.

Research output: Contribution to journalArticle

156 Scopus citations
2008

Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy

Shi, J., Zhang, Y. W., Summers, L. J., Dorn, G. W. & Wei, L., Mar 2008, In : Journal of Molecular and Cellular Cardiology. 44, 3, p. 551-560 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2009

Targeted disruption of ROCK1 causes insulin resistance in vivo

Lee, D. H., Shi, J., Jeoung, N. H., Kim, M. S., Zabolotny, J. M., Lee, S. W., White, M. F., Wei, L. & Kim, Y. B., May 1 2009, In : Journal of Biological Chemistry. 284, 18, p. 11776-11780 5 p.

Research output: Contribution to journalArticle

82 Scopus citations
2010

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

Vemula, S., Shi, J., Hanneman, P., Wei, L. & Kapur, R., Mar 4 2010, In : Blood. 115, 9, p. 1785-1796 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

ROCK1 plays an essential role in the transition from cardiac hypertrophy to failure in mice

Shi, J., Zhang, Y. W., Yang, Y., Zhang, L. & Wei, L., Nov 2010, In : Journal of Molecular and Cellular Cardiology. 49, 5, p. 819-828 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
2011

Amelioration of albuminuria in ROCK1 knockout mice with streptozotocin-induced diabetic kidney disease

Zhou, L., Liu, F., Huang, X. R., Liu, F., Chen, H., Chung, A. C. K., Shi, J., Wei, L., Lan, H. Y. & Fu, P., Nov 1 2011, In : American journal of nephrology. 34, 5, p. 468-475 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effects of rosiglitazone on abnormal lipid kinetics in HIV-associated dyslipidemic lipodystrophy: A stable isotope study

Sekhar, R. V., Patel, S. G., D'Amico, S., Shi, J., Balasubramanyam, A., Rehman, K., Jahoor, F. & Visnegarwala, F., Jun 1 2011, In : Metabolism: Clinical and Experimental. 60, 6, p. 754-760 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rho-kinase in development and heart failure: Insights from genetic models

Shi, J., Zhang, L. & Wei, L., Mar 2011, In : Pediatric Cardiology. 32, 3, p. 297-304 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL

Mali, R. S., Ramdas, B., Ma, P., Shi, J., Munugalavadla, V., Sims, E., Wei, L., Vemula, S., Nabinger, S. C., Goodwin, C. B., Chan, R. J., Traina, F., Visconte, V., Tiu, R. V., Lewis, T. A., Stern, A. M., Wen, Q., Crispino, J. D., Boswell, H. S. & Kapur, R., Sep 1 2011, In : Cancer Cell. 20, 3, p. 357-369 13 p.

Research output: Contribution to journalArticle

59 Scopus citations
2012

Downregulation of doxorubicin-induced myocardial apoptosis accompanies postnatal heart maturation

Shi, J., Zhang, L., Zhang, Y. W., Surma, M., Mark Payne, R. & Wei, L., Apr 15 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 8, p. H1603-H1613

Research output: Contribution to journalArticle

23 Scopus citations

Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL

Wen, Q., Goldenson, B., Silver, S. J., Schenone, M., Dancik, V., Huang, Z., Wang, L. Z., Lewis, T. A., An, W. F., Li, X., Bray, M. A., Thiollier, C., Diebold, L., Gilles, L., Vokes, M. S., Moore, C. B., Bliss-Moreau, M., Verplank, L., Tolliday, N. J., Mishra, R. & 28 others, Vemula, S., Shi, J., Wei, L., Kapur, R., Lopez, C. K., Gerby, B., Ballerini, P., Pflumio, F., Gilliland, D. G., Goldberg, L., Birger, Y., Izraeli, S., Gamis, A. S., Smith, F. O., Woods, W. G., Taub, J., Scherer, C. A., Bradner, J. E., Goh, B. C., Mercher, T., Carpenter, A. E., Gould, R. J., Clemons, P. A., Carr, S. A., Root, D. E., Schreiber, S. L., Stern, A. M. & Crispino, J. D., Aug 3 2012, In : Cell. 150, 3, p. 575-589 15 p.

Research output: Contribution to journalArticle

89 Scopus citations

Regulation of the actin cytoskeleton by rho kinase controls antigen presentation by CD1d

Gallo, R. M., Khan, M. A., Shi, J., Kapur, R., Wei, L., Bailey, J. C., Liu, J. & Brutkiewicz, R. R., Aug 15 2012, In : Journal of Immunology. 189, 4, p. 1689-1698 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

Vemula, S., Shi, J., Mali, R. S., Ma, P., Liu, Y., Hanneman, P., Koehler, K. R., Hashino, E., Wei, L. & Kapur, R., Oct 4 2012, In : Blood. 120, 14, p. 2868-2878 11 p.

Research output: Contribution to journalArticle

24 Scopus citations
7 Scopus citations
2013

Determination of trace amount of Cu2+ with a multi-responsive colorimetric and reversible chemosensor

Mi, Y. S., Cao, Z., Chen, Y. T., Xie, Q. F., Xu, Y. Y., Luo, Y. F., Shi, J. J. & Xiang, J. N., Sep 21 2013, In : Analyst. 138, 18, p. 5274-5280 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

Shi, J., Wu, X., Surma, M., Vemula, S., Zhang, L., Yang, Y., Kapur, R. & Wei, L., Feb 2013, In : Cell Death and Disease. 4, 2

Research output: Contribution to journalArticle

94 Scopus citations
2014

Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure

Yue, X., Yang, X., Lin, X., Yang, T., Yi, X., Dai, Y., Guo, J., Li, T., Shi, J., Wei, L., Fan, G. C., Chen, C. & Chang, J., Jun 2014, In : Cell Death and Disease. 5, 6, e1284.

Research output: Contribution to journalArticle

12 Scopus citations

ROCK1 deficiency enhances protective effects of antioxidants against apoptosis and cell detachment

Surma, M., Handy, C., Chang, J., Kapur, R., Wei, L. & Shi, J., Mar 4 2014, In : PLoS ONE. 9, 3, e90758.

Research output: Contribution to journalArticle

22 Scopus citations

ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance

Lee, S. H., Huang, H., Choi, K., Lee, D. H., Shi, J., Liu, T., Chun, K. H., Seo, J. A., Lima, I. S., Zabolotny, J. M., Wei, L. & Kim, Y. B., Feb 1 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 3, p. E332-E343

Research output: Contribution to journalArticle

29 Scopus citations
2015

Dissecting the mechanisms of doxorubicin and oxidative stress-induced cytotoxicity: The involvement of actin cytoskeleton and ROCK1

Wei, L., Surma, M., Gough, G., Shi, S., Lambert-Cheatham, N., Chang, J. & Shi, J., Jul 2 2015, In : PloS one. 10, 7, e0131763.

Research output: Contribution to journalArticle

27 Scopus citations
2016

Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1α/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1α and Regulates Responsive Cardiac Angiogenesis

Yue, X., Lin, X., Yang, T., Yang, X., Yi, X., Jiang, X., Li, X., Li, T., Guo, J., Dai, Y., Shi, J., Wei, L., Youker, K. A., Torre-Amione, G., Yu, Y., Andrade, K. C. & Chang, J., Mar 1 2016, In : Hypertension. 67, 3, p. 597-605 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

Kapur, R., Shi, J., Ghosh, J., Munugalavadla, V., Sims, E., Martin, H., Wei, L. & Mali, R. S., Mar 29 2016, In : Oncotarget. 7, 13, p. 16936-16947 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity

Shi, J., Surma, M. & Wei, L., 2018, In : Oncotarget. 9, 16, p. 12995-13008 14 p.

Research output: Contribution to journalArticle

8 Scopus citations
2019

Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging

Shi, J., Surma, M., Yang, Y. & Wei, L., Jun 1 2019, In : FASEB Journal. 33, 6, p. 7348-7362 15 p.

Research output: Contribution to journalArticle

8 Scopus citations
2020

ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice

Wei, L., Surma, M., Yang, Y., Tersey, S. & Shi, J., Jan 1 2020, In : FASEB Journal. 34, 1, p. 474-493 20 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations