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John Chirgwin

  • 25291 Citations
  • 47 h-Index
1972 …2020

Research output per year

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NIH Grants

Role of Osteocytes in Myeloma Bone Disease

Chirgwin, J. & Suvannasankha, A.

Project: Research project

A Novel Agent to Suppress Tumor Growth in Bone, Prevent Cachectic Muscle Loss and Preserve Skeletal Integrity

Chirgwin, J. & Suvannasankha, A.

Project: Research project

Publications

Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo

Miyagawa, K., Ohata, Y., Delgado-Calle, J., Teramachi, J., Zhou, H., Dempster, D. D., Subler, M. A., Windle, J. J., Chirgwin, J. M., David Roodman, G. & Kurihara, N., Mar 26 2020, In : JCI Insight. 5, 6, e133113.

Research output: Contribution to journal › Article

Open Access

    • Small molecules inhibit ex vivo tumor growth in bone

    Zhou, D., Bum-Erdene, K., Xu, D., Liu, D., Tompkins, D., Sulaiman, R. S., Corson, T. W., Chirgwin, J. M. & Meroueh, S. O., Dec 15 2018, In : Bioorganic and Medicinal Chemistry. 26, 23-24, p. 6128-6134 7 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    The role of Semaphorin 4D in bone remodeling and cancer metastasis

    Lontos, K., Adamik, J., Tsagianni, A., Galson, D. L., Chirgwin, J. M. & Suvannasankha, A., Jun 19 2018, In : Frontiers in Endocrinology. 9, JUL, 322.

    Research output: Contribution to journal › Review article

    • 8 Scopus citations

    Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

    Juárez, P., Fournier, P. G. J., Mohammad, K. S., McKenna, R. C., Davis, H. W., Peng, X. H., Niewolna, M., Mauviel, A., Chirgwin, J. M. & Guise, T. A., Oct 17 2017, In : Oncotarget. 8, 49, p. 86447-86462 16 p.

    Research output: Contribution to journal › Article

    • 9 Scopus citations

    Bidirectional notch signaling and osteocyte-derived factors in the bone marrow microenvironment promote tumor cell proliferation and bone destruction in multiple myeloma

    Delgado-Calle, J., Anderson, J., Cregor, M. D., Hiasa, M., Chirgwin, J. M., Carlesso, N., Yoneda, T., Mohammad, K. S., Plotkin, L. I., Roodman, G. D. & Bellido, T., Mar 1 2016, In : Cancer Research. 76, 5, p. 1089-1100 12 p.

    Research output: Contribution to journal › Article

    • 80 Scopus citations