John Nurnberger

  • Joyce & Iver Small Professor of Psychiatry, Psychiatry
  • 38629 Citations
  • 94 h-Index
1968 …2020

Research output per year

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Publications

2011

Identification of blood biomarkers for psychosis using convergent functional genomics

Kurian, S. M., Le-Niculescu, H., Patel, S. D., Bertram, D., Davis, J., Dike, C., Yehyawi, N., Lysaker, P., Dustin, J., Caligiuri, M., Lohr, J., Lahiri, D. K., Nurnberger, J. I., Faraone, S. V., Geyer, M. A., Tsuang, M. T., Schork, N. J., Salomon, D. R. & Niculescu, A. B., Jan 1 2011, In : Molecular Psychiatry. 16, 1, p. 37-58 22 p.

Research output: Contribution to journalArticle

98 Scopus citations

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., Blackwood, D., Corvin, A., Flickinger, M., Guan, W., Mattingsdal, M., McQuillin, A., Kwan, P., Wienker, T. F., Daly, M., Dudbridge, F., Holmans, P. A. & 152 others, Lin, D., Burmeister, M., Greenwood, T. A., Hamshere, M. L., Muglia, P., Smith, E. N., Zandi, P. P., Nievergelt, C. M., McKinney, R., Shilling, P. D., Schork, N. J., Bloss, C. S., Foroud, T., Koller, D. L., Gershon, E. S., Liu, C., Badner, J. A., Scheftner, W. A., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F. J., Schulze, T. G., Berrettini, W., Lohoff, F. W., Potash, J. B., Mahon, P. B., McInnis, M. G., Zöllner, S., Zhang, P., Craig, D. W., Szelinger, S., Barrett, T. B., Breuer, R., Meier, S., Strohmaier, J., Witt, S. H., Tozzi, F., Farmer, A., McGuffin, P., Strauss, J., Xu, W., Kennedy, J. L., Vincent, J. B., Matthews, K., Day, R., Ferreira, M. A., O'Dushlaine, C., Perlis, R., Raychaudhuri, S., Ruderfer, D., Lee, P. H., Smoller, J. W., Li, J., Absher, D., Bunney, W. E., Barchas, J. D., Schatzberg, A. F., Jones, E. G., Meng, F., Thompson, R. C., Watson, S. J., Myers, R. M., Akil, H., Boehnke, M., Chambert, K., Moran, J., Scolnick, E., Djurovic, S., Melle, I., Morken, G., Gill, M., Morris, D., Quinn, E., Mühleisen, T. W., Degenhardt, F. A., Mattheisen, M., Schumacher, J., Maier, W., Steffens, M., Propping, P., Nöthen, M. M., Anjorin, A., Bass, N., Gurling, H., Kandaswamy, R., Lawrence, J., McGhee, K., McIntosh, A., McLean, A. W., Muir, W. J., Pickard, B. S., Breen, G., St. Clair, D., Caesar, S., Gordon-Smith, K., Jones, L., Fraser, C., Green, E. K., Grozeva, D., Jones, I. R., Kirov, G., Moskvina, V., Nikolov, I., O'Donovan, M. C., Owen, M. J., Collier, D. A., Elkin, A., Williamson, R., Young, A. H., Nicol Ferrier, I., Stefansson, K., Stefansson, H., Porgeirsson, P., Steinberg, S., Gustafsson, Ó., Bergen, S. E., Nimgaonkar, V., Hultman, C., Landén, M., Lichtenstein, P., Sullivan, P., Schalling, M., Osby, U., Backlund, L., Frisén, L., Langstrom, N., Jamain, S., Leboyer, M., Etain, B., Bellivier, F., Petursson, H., Sigurdsson, E., Müller-Mysok, B., Lucae, S., Schwarz, M., Fullerton, J. M., Schofield, P. R., Martin, N., Montgomery, G. W., Lathrop, M., Óskarsson, H., Bauer, M., Wright, A., Mitchell, P. B., Hautzinger, M., Reif, A., Kelsoe, J. R. & Purcell, S. M., Oct 2011, In : Nature genetics. 43, 10, p. 977-985 9 p.

Research output: Contribution to journalArticle

879 Scopus citations

McMahon et al. reply

McMahon, F. J., Akula, N., Cichon, S., Detera-Wadleigh, S. D., Edenberg, H., Holsboer, F., Nöthen, M. M., Nurnberger, J. I., Potash, J., Preisig, M., Rietschel, M. & Schulze, T. G., Jan 1 2011, In : Nature genetics. 43, 1, 1 p.

Research output: Contribution to journalLetter

The AVPR1A gene and substance use disorders: Association, replication, and functional evidence

Maher, B. S., Vladimirov, V. I., Latendresse, S. J., Thiselton, D. L., McNamee, R., Kang, M., Bigdeli, T. B., Chen, X., Riley, B. P., Hettema, J. M., Chilcoat, H., Heidbreder, C., Muglia, P., Murrelle, E. L., Dick, D. M., Aliev, F., Agrawal, A., Edenberg, H. J., Kramer, J., Nurnberger, J. & 7 others, Tischfield, J. A., Devlin, B., Ferrell, R. E., Kirillova, G. P., Tarter, R. E., Kendler, K. S. & Vanyukov, M. M., Sep 15 2011, In : Biological psychiatry. 70, 6, p. 519-527 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
2010

A genome-wide association study of alcohol dependence

Bierut, L. J., Agrawal, A., Bucholz, K. K., Doheny, K. F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., Hinrichs, A. L., Almasy, L., Breslau, N., Culverhouse, R. C., Dick, D. M., Edenberg, H. J., Foroud, T., Grucza, R. A., Hatsukami, D., Hesselbrock, V. & 19 others, Johnson, E. O., Kramer, J., Krueger, R. F., Kuperman, S., Lynskey, M., Mann, K., Neuman, R. J., Nöthen, M. M., Nurnberger, J. I., Porjesz, B., Ridinger, M., Saccone, N. L., Saccone, S. F., Schuckit, M. A., Tischfield, J. A., Wang, J. C., Rietschel, M., Goate, A. M. & Rice, J. P., Mar 16 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 11, p. 5082-5087 6 p.

Research output: Contribution to journalArticle

340 Scopus citations

A genome-wide scan for common alleles affecting risk for autism

Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., Sykes, N., Pagnamenta, A. T., Almeida, J., Bacchelli, E., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bölte, S., Bolton, P. F., Bourgeron, T. & 146 others, Brennan, S., Brian, J., Carson, A. R., Casallo, G., Casey, J., Chu, S. H., Cochrane, L., Corsello, C., Crawford, E. L., Crossett, A., Dawson, G., de Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B. A., Folstein, S. E., Fombonne, E., Freitag, C. M., Gilbert, J., Gillberg, C., Glessner, J. T., Goldberg, J., Green, J., Guter, S. J., Hakonarson, H., Heron, E. A., Hill, M., Holt, R., Howe, J. L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S. M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C. M., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B. L., Lionel, A. C., Liu, X. Q., Lord, C., Lotspeich, L., Lund, S. C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C. R., McConachie, H., McDougle, C. J., McGrath, J., McMahon, W. M., Melhem, N. M., Merikangas, A., Migita, O., Minshew, N. J., Mirza, G. K., Munson, J., Nelson, S. F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J. R., Parrini, B., Paton, T., Pickles, A., Piven, J., Posey, D. J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M. L., Bierut, L. J., Rice, J. P., Salt, J., Sansom, K., Sato, D., Segurado, R., Senman, L., Shah, N., Sheffield, V. C., Soorya, L., Sousa, I., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A. P., Thomson, S., Tryfon, A., Tsiantis, J., van Engeland, H., Vincent, J. B., Volkmar, F., Wallace, S., Wang, K., Wang, Z., Wassink, T. H., Wing, K., Wittemeyer, K., Wood, S., Yaspan, B. L., Zurawiecki, D., Zwaigenbaum, L., Betancur, C., Buxbaum, J. D., Cantor, R. M., Cook, E. H., Coon, H., Cuccaro, M. L., Gallagher, L., Geschwind, D. H., Gill, M., Haines, J. L., Miller, J., Monaco, A. P., Nurnberger, J. I., Paterson, A. D., Pericak-Vance, M. A., Schellenberg, G. D., Scherer, S. W., Sutcliffe, J. S., Szatmari, P., Vicente, A. M., Vieland, V. J., Wijsman, E. M., Devlin, B., Ennis, S. & Hallmayer, J., Jul 27 2010, In : Human molecular genetics. 19, 20, p. 4072-4082 11 p.

Research output: Contribution to journalArticle

400 Scopus citations

An investigation of candidate regions for association with bipolar disorder

NIMH Genetics Initiative Bipolar Disorder Consortium, Oct 1 2010, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 7, p. 1292-1297 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

A principal components analysis of the abbreviated desires for alcohol questionnaire (DAQ)

Kramer, J. R., Chan, G., Hesselbrock, V. M., Kuperman, S., Bucholz, K. K., Edenberg, H. J., Schuckit, M. A., Nurnberger, J. I., Foroud, T., Dick, D. M., Bierut, L. J. & Porjesz, B., Jan 2010, In : Journal of studies on alcohol and drugs. 71, 1, p. 150-155 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts

Kalsi, G., Kuo, P. H., Aliev, F., Alexander, J., McMichael, O., Patterson, D. G., Walsh, D., Zhao, Z., Schuckit, M., Nurnberger, J. J., Edenberg, H., Kramer, J., Vladimirov, V., Prescott, C. A., Dick, D. M., Kendler, K. S. & Riley, B. P., Jun 15 2010, In : Human molecular genetics. 19, 12, p. 2497-2506 10 p., ddq112.

Research output: Contribution to journalArticle

14 Scopus citations
52 Scopus citations

Corrigendum: A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts

Kalsi, G., Kuo, P. H., Aliev, F., Alexander, J., McMichael, O., Patterson, D. G., Walsh, D., Zhao, Z., Schuckit, M., Nurnberger, J., Edenberg, H., Kramer, J., Hesselbrock, V., Tischfield, J. A., Vladimirov, V., Prescott, C. A., Dick, D. M., Kendler, K. S. & Riley, B. P., Aug 10 2010, In : Human molecular genetics. 19, 20, 1 p., ddq326.

Research output: Contribution to journalComment/debate

Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts

Dick, D. M., Meyers, J., Aliev, F., Nurnberger, J., Kramer, J., Kuperman, S., Porjesz, B., Tischfield, J., Edenberg, H. J., Foroud, T., Schuckit, M., Goate, A., Hesselbrock, V. & Bierut, L., Sep 1 2010, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 6, p. 1179-1188 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Functional impact of global rare copy number variation in autism spectrum disorders

Pinto, D., Pagnamenta, A. T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., Almeida, J., Bacchelli, E., Bader, G. D., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bölte, S., Bolton, P. F. & 157 others, Bourgeron, T., Brennan, S., Brian, J., Bryson, S. E., Carson, A. R., Casallo, G., Casey, J., Chung, B. H. Y., Cochrane, L., Corsello, C., Crawford, E. L., Crossett, A., Cytrynbaum, C., Dawson, G., De Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B. A., Folstein, S. E., Fombonne, E., Freitag, C. M., Gilbert, J., Gillberg, C., Glessner, J. T., Goldberg, J., Green, A., Green, J., Guter, S. J., Hakonarson, H., Heron, E. A., Hill, M., Holt, R., Howe, J. L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S. M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C. M., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B. L., Lionel, A. C., Liu, X. Q., Lord, C., Lotspeich, L., Lund, S. C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C. R., McConachie, H., McDougle, C. J., McGrath, J., McMahon, W. M., Merikangas, A., Migita, O., Minshew, N. J., Mirza, G. K., Munson, J., Nelson, S. F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J. R., Parrini, B., Paton, T., Pickles, A., Pilorge, M., Piven, J., Ponting, C. P., Posey, D. J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M. L., Bierut, L. J., Rice, J. P., Salt, J., Sansom, K., Sato, D., Segurado, R., Sequeira, A. F., Senman, L., Shah, N., Sheffield, V. C., Soorya, L., Sousa, I., Stein, O., Sykes, N., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A. P., Thomson, S., Tryfon, A., Tsiantis, J., Van Engeland, H., Vincent, J. B., Volkmar, F., Wallace, S., Wang, K., Wang, Z., Wassink, T. H., Webber, C., Weksberg, R., Wing, K., Wittemeyer, K., Wood, S., Wu, J., Yaspan, B. L., Zurawiecki, D., Zwaigenbaum, L., Buxbaum, J. D., Cantor, R. M., Cook, E. H., Coon, H., Cuccaro, M. L., Devlin, B., Ennis, S., Gallagher, L., Geschwind, D. H., Gill, M., Haines, J. L., Hallmayer, J., Miller, J., Monaco, A. P., Nurnberger, J. I., Paterson, A. D., Pericak-Vance, M. A., Schellenberg, G. D., Szatmari, P., Vicente, A. M., Vieland, V. J., Wijsman, E. M., Scherer, S. W., Sutcliffe, J. S. & Betancur, C., Jul 15 2010, In : Nature. 466, 7304, p. 368-372 5 p.

Research output: Contribution to journalArticle

1296 Scopus citations

GABRR1 and GABRR2, encoding the GABA-A receptor subunits ρ1 and ρ2, are associated with alcohol dependence

Xuei, X., Flury-Wetherill, L., Dick, D., Goate, A., Tischfield, J., Nurnberger, J., Schuckit, M., Kramer, J., Kuperman, S., Hesselbrock, V., Porjesz, B., Foroud, T. & Edenberg, H. J., Mar 1 2010, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 2, p. 418-427 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Genome-wide association study of alcohol dependence implicates a region on chromosome 11

Edenberg, H. J., Koller, D. L., Xuei, X., Wetherill, L., McClintick, J. N., Almasy, L., Bierut, L. J., Bucholz, K. K., Goate, A., Aliev, F., Dick, D., Hesselbrock, V., Hinrichs, A., Kramer, J., Kuperman, S., Nurnberger, J. I., Rice, J. P., Schuckit, M. A., Taylor, R., Todd Webb, B. & 3 others, Tischfield, J. A., Porjesz, B. & Foroud, T., May 1 2010, In : Alcoholism: Clinical and Experimental Research. 34, 5, p. 840-852 13 p.

Research output: Contribution to journalArticle

228 Scopus citations

Item response modeling of DSM-IV mania symptoms in two representative US epidemiological samples

Agrawal, A., Nurnberger, J. I. & Lynskey, M. T., Sep 1 2010, In : Psychological Medicine. 40, 9, p. 1549-1558 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Obesity, smoking, and frontal brain dysfunction

Bauer, L., Dick, D., Bierut, L., Bucholz, K., Edenberg, H., Kuperman, S., Kramer, J., Nurnberger, J., O'Connor, S., Rice, J., Rohrbaugh, J., Schuckit, M., Tischfield, J., Porjesz, B. & Hesselbrock, V., Sep 1 2010, In : American Journal on Addictions. 19, 5, p. 391-400 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Predicting sensation seeking from dopamine genes: A candidate-system approach

Derringer, J., Krueger, R. F., Dick, D. M., Saccone, S., Grucza, R. A., Agrawal, A., Lin, P., Almasy, L., Edenberg, H. J., Foroud, T., Nurnberger, J. I., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Porjesz, B., Schuckit, M. A. & Bierut, L. J., Sep 1 2010, In : Psychological Science. 21, 9, p. 1282-1290 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Predictors of sexual debut at age 16 or younger

Cavazos-Rehg, P. A., Spitznagel, E. L., Bucholz, K. K., Nurnberger, J., Edenberg, H. J., Kramer, J. R., Kuperman, S., Hesselbrock, V. & Bierut, L. J., Jun 1 2010, In : Archives of Sexual Behavior. 39, 3, p. 664-673 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence

Chen, A. C. H., Manz, N., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger, J., O'Connor, S. J., Edenberg, H. J., Schuckit, M. A., Tischfield, J., Foroud, T., Bierut, L. J., Rohrbaugh, J., Rice, J. P., Goate, A., Hesselbrock, V. & Porjesz, B., Jun 2010, In : Alcoholism: Clinical and Experimental Research. 34, 6, p. 988-996 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2009

A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA)

Kramer, J. R., Chan, G., Kuperman, S., Bucholz, K. K., Edenberg, H. J., Schuckit, M. A., Polgreen, L. A., Kapp, E. S., Hesselbrock, V. M., Nurnberger, J. I. & Bierut, L. J., Jan 1 2009, In : Journal of studies on alcohol and drugs. 70, 4, p. 623-627 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

A genome-wide linkage and association scan reveals novel loci for autism

Weiss, L. A., Arking, D. E., Daly, M. J., Chakravarti, A., Brune, C. W., West, K., O'Connor, A., Hilton, G., Tomlinson, R. L., West, A. B., Cook, E. H., Green, T., Chang, S. C., Gabriel, S., Gates, C., Hanson, E. M., Kirby, A., Korn, J., Kuruvilla, F., McCarroll, S. & 169 others, Morrow, E. M., Neale, B., Purcell, S., Sasanfar, R., Sougnez, C., Stevens, C., Altshuler, D., Gusella, J., Santangelo, S. L., Sklar, P., Tanzi, R., Anney, R., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Betancur, C., Bölte, S., Bolton, P. F., Brian, J., Bryson, S. E., Buxbaum, J. D., Cabrito, I., Cai, G., Cantor, R. M., Coon, H., Conroy, J., Correia, C., Corsello, C., Crawford, E. L., Cuccaro, M. L., Dawson, G., De Jonge, M., Devlin, B., Duketis, E., Ennis, S., Estes, A., Farrar, P., Fombonne, E., Freitag, C. M., Gallagher, L., Geschwind, D. H., Gilbert, J., Gill, M., Gillberg, C., Goldberg, J., Green, A., Green, J., Guter, S. J., Haines, J. L., Hallmayer, J. F., Hus, V., Klauck, S. M., Korvatska, O., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventha, B. L., Liu, X. Q., Lord, C., Lotspeich, L. J., Maestrini, E., Magalhaes, T., Mahoney, W., Mantoulan, C., McConachie, H., McDougle, C. J., McMahon, W. M., Marshall, C. R., Miller, J., Minshew, N. J., Monaco, A. P., Munson, J., Nurnberger, J. I., Oliveira, G., Pagnamenta, A., Papanikolaou, K., Parr, J. R., Paterson, A. D., Pericak-Vance, M. A., Pickles, A., Pinto, D., Piven, J., Posey, D. J., Poustka, A., Poustka, F., Regan, R., Reichert, J., Renshaw, K., Roberts, W., Roge, B., Rutter, M. L., Salt, J., Schellenberg, G. D., Scherer, S. W., Sheffield, V., Sutcliffe, J. S., Szatmari, P., Tansey, K., Thompson, A. P., Tsiantis, J., Van Engeland, H., Vicente, A. M., Vieland, V. J., Volkmar, F., Wallace, S., Wassink, T. H., Wijsman, E. M., Wing, K., Wittemeyer, K., Yaspan, B. L., Zwaigenbaum, L., Yoo, S. Y., Hill, R. S., Mukaddes, N. M., Balkhy, S., Gascon, G., Al-Saad, S., Hashmi, A., Ware, J., Joseph, R. M., LeClair, E., Partlow, J. N., Barry, B., Walsh, C. A., Pauls, D., Moilanen, I., Ebeling, H., Mattila, M. L., Kuusikko, S., Jussila, K., Ignatius, J., Tolouei, A., Ghadami, M., Rostami, M., Hosseinipour, A., Valujerdi, M., Andresen, K., Winkloski, B., Haddad, S., Kunkel, L., Kohane, Z., Tran, T., Won Kong, S., O'Neil, S. B., Hundley, R., Holm, I., Peters, H., Baroni, E., Cangialose, A., Jackson, L., Albers, L., Becker, R., Bridgemohan, C., Friedman, S., Munir, K., Nazir, R., Palfrey, J., Schonwald, A., Simmons, E., Rappaport, L. A., Gauthier, J., Mottron, L., Joober, R., Rouleau, G., Rehnstrom, K., Von Wendt, L. & Peltonen, L., Oct 8 2009, In : Nature. 461, 7265, p. 802-808 7 p.

Research output: Contribution to journalArticle

433 Scopus citations

Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence

Chen, A. C. H., Tang, Y., Rangaswamy, M., Wang, J. C., Almasy, L., Foroud, T., Edenberg, H. J., Hesselbrock, V., Nurnberger, J., Kuperman, S., O'Connor, S. J., Schuckit, M. A., Bauer, L. O., Tischfield, J., Rice, J. P., Bierut, L., Goate, A. & Porjesz, B., Apr 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 3, p. 359-368 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

Glessner, J. T., Wang, K., Cai, G., Korvatska, O., Kim, C. E., Wood, S., Zhang, H., Estes, A., Brune, C. W., Bradfield, J. P., Imielinski, M., Frackelton, E. C., Reichert, J., Crawford, E. L., Munson, J., Sleiman, P. M. A., Chiavacci, R., Annaiah, K., Thomas, K., Hou, C. & 39 others, Glaberson, W., Flory, J., Otieno, F., Garris, M., Soorya, L., Klei, L., Piven, J., Meyer, K. J., Anagnostou, E., Sakurai, T., Game, R. M., Rudd, D. S., Zurawiecki, D., McDougle, C. J., Davis, L. K., Miller, J., Posey, D. J., Michaels, S., Kolevzon, A., Silverman, J. M., Bernier, R., Levy, S. E., Schultz, R. T., Dawson, G., Owley, T., McMahon, W. M., Wassink, T. H., Sweeney, J. A., Nurnberger, J. I., Coon, H., Sutcliffe, J. S., Minshew, N. J., Grant, S. F. A., Bucan, M., Cook, E. H., Buxbaum, J. D., Devlin, B., Schellenberg, G. D. & Hakonarson, H., May 28 2009, In : Nature. 459, 7246, p. 569-572 4 p.

Research output: Contribution to journalArticle

918 Scopus citations

Common genetic variants on 5p14.1 associate with autism spectrum disorders

Wang, K., Zhang, H., Ma, D., Bucan, M., Glessner, J. T., Abrahams, B. S., Salyakina, D., Imielinski, M., Bradfield, J. P., Sleiman, P. M. A., Kim, C. E., Hou, C., Frackelton, E., Chiavacci, R., Takahashi, N., Sakurai, T., Rappaport, E., Lajonchere, C. M., Munson, J., Estes, A. & 36 others, Korvatska, O., Piven, J., Sonnenblick, L. I., Alvarez Retuerto, A. I., Herman, E. I., Dong, H., Hutman, T., Sigman, M., Ozonoff, S., Klin, A., Owley, T., Sweeney, J. A., Brune, C. W., Cantor, R. M., Bernier, R., Gilbert, J. R., Cuccaro, M. L., McMahon, W. M., Miller, J., State, M. W., Wassink, T. H., Coon, H., Levy, S. E., Schultz, R. T., Nurnberger, J. I., Haines, J. L., Sutcliffe, J. S., Cook, E. H., Minshew, N. J., Buxbaum, J. D., Dawson, G., Grant, S. F. A., Geschwind, D. H., Pericak-Vance, M. A., Schellenberg, G. D. & Hakonarson, H., May 28 2009, In : Nature. 459, 7246, p. 528-533 6 p.

Research output: Contribution to journalArticle

693 Scopus citations

Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

Le-Niculescu, H., Patel, S. D., Bhat, M., Kuczenski, R., Faraone, S. V., Tsuang, M. T., McMahon, F. J., Schork, N. J., Nurnberger, J. I. & Niculescu, A. B., Mar 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 2, p. 155-181 27 p.

Research output: Contribution to journalArticle

139 Scopus citations

Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter DOlvmorDhism

Maloney, B., Ray, B., Hayden, E. R., Nurnberger, J. I. & Lahiri, D. K., Apr 1 2009, In : Psychiatric genetics. 19, 2, p. 72-82 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dissecting the phenotype in genome-wide association studies of psychiatric illness

Craddock, N., Kendler, K., Neale, M., Nurnberger, J., Purcell, S., Rietschel, M., Perlis, R., Santangelo, S. L., Schulze, T., Smoller, J. W. & Thapar, A., Aug 1 2009, In : British Journal of Psychiatry. 195, 2, p. 97-99 3 p.

Research output: Contribution to journalReview article

48 Scopus citations

Erratum: Identifying blood biomarkers for mood disorders using convergent functional genomics (Molecular Psychiatry (2009) 14 (156-174) DOI: 10.1038/mp.2008.11)

Le-Niculescu, H., Kurian, S. M., Yehyawi, N., Dike, C., Patel, S. D., Edenberg, H. J., Tsuang, M. T., Salomon, D. R., Nurnberger, J. I. & Niculescu, A. B., Dec 1 2009, In : Molecular Psychiatry. 14, 12, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence

Agrawal, A., Wetherill, L., Dick, D. M., Xuei, X., Hinrichs, A., Hesselbrock, V., Kramer, J., Nurnberger, J. I., Schuckit, M., Bierut, L. J., Edenberg, H. J. & Foroud, T., Jul 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 5, p. 736-740 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Eyeblink conditioning anomalies in bipolar disorder suggest cerebellar dysfunction

Bolbecker, A. R., Mehta, C., Johannesen, J. K., Edwards, C. R., O'donnell, B. F., Shekhar, A., Nurnberger, J. I., Steinmetz, J. E. & Hetrick, W. P., Jan 19 2009, In : Bipolar Disorders. 11, 1, p. 19-32 14 p.

Research output: Contribution to journalArticle

33 Scopus citations

Family-based association of FKBP5 in bipolar disorder

Willour, V. L., Chen, H., Toolan, J., Belmonte, P., Cutler, D. J., Goes, F. S., Zandi, P. P., Lee, R. S., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., DePaulo, J. R., Gershon, E., McMahon, F. J., Potash, J. B., Miller, E., Pearl, J., Kassem, L., Lopez, V., Nurnberger, J. & 46 others, Miller, M. J., Bowman, E. S., Reich, T., Goate, A., Rice, J., Stine, C., Kazuba, D., Maxwell, E., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Bierut, L., McInnis, M., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Badner, J., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Jan 1 2009, In : Molecular Psychiatry. 14, 3, p. 261-268 8 p.

Research output: Contribution to journalArticle

124 Scopus citations

Family-based association of YWHAH in psychotic bipolar disorder

Grover, D., Verma, R., Goes, F. S., Belmonte Mahon, P. L., Gershon, E. S., McMahon, F. J., Potash, J. B., Steele, J., Kassem, L., Pearl, J., Schulze, T., MacKinnon, D. F., Miller, E., Toolan, J., Zandi, P. P., Simpson, S., Nurnberger, J., Miller, M. J., Bowman, E. S., Reich, T. & 45 others, Goate, A., Rice, J., DePaulo, J. R., Stine, C., Kazuba, D., Maxwell, E., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Bierut, L., McInnis, M., Mondimore, F. M., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Badner, J., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Oct 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 7, p. 977-983 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

Wang, J. C., Grucza, R., Cruchaga, C., Hinrichs, A. L., Bertelsen, S., Budde, J. P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B. & 3 others, Edenberg, H. J., Bierut, L. J. & Goate, A. M., May 1 2009, In : Molecular Psychiatry. 14, 5, p. 501-510 10 p.

Research output: Contribution to journalArticle

158 Scopus citations

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

Bucan, M., Abrahams, B. S., Wang, K., Glessner, J. T., Herman, E. I., Sonnenblick, L. I., Alvarez Retuerto, A. I., Imielinski, M., Hadley, D., Bradfield, J. P., Kim, C., Gidaya, N. B., Lindquist, I., Hutman, T., Sigman, M., Kustanovich, V., Lajonchere, C. M., Singleton, A., Kim, J., Wassink, T. H. & 16 others, McMahon, W. M., Owley, T., Sweeney, J. A., Coon, H., Nurnberger, J. I., Li, M., Cantor, R. M., Minshew, N. J., Sutcliffe, J. S., Cook, E. H., Dawson, G., Buxbaum, J. D., Grant, S. F. A., Schellenberg, G. D., Geschwind, D. H. & Hakonarson, H., Jun 1 2009, In : PLoS Genetics. 5, 6, e1000536.

Research output: Contribution to journalArticle

287 Scopus citations

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Cichon, S., Craddock, N., Daly, M., Faraone, S. V., Gejman, P. V., Kelsoe, J., Lehner, T., Levinson, D. F., Moran, A., Sklar, P., Sullivan, P. F., Anney, R., Gill, M., Corvin, A., Buitelaar, J., Franke, B., Elia, J., Hakonarson, H., Kent, L., McGough, J. & 103 others, Smalley, S., Ophoff, R., Mick, E., Santangelo, S., Ferreira, M., Purcell, S., Ruderfer, D., Smoller, J., Perlis, R., Neale, B., Stone, J., Nisenbaum, L., Thapar, A., Moskvina, V., Holmans, P., O'Donovan, M., Owen, M., Todd, R., Todorov, A., Rice, J., Devlin, B., Arking, D., Chakravarti, A., Potash, J. B., Pulver, A., Buxbaum, J. D., Cook, E., Peltonen, L., Suvisaari, J., Piven, J., Lin, D., Sullivan, P., Rouleau, G., Awadalla, P., Schellenberg, G., Scherer, S., Sutcliffe, J., Szatmari, P., Vieland, V., Andreassen, O. A., Frigessi, A., Blackwood, D., Muir, W., Boehnke, M., Burmeister, M., Flickinger, M., Guan, W., Li, J., Scott, L., Breuer, R., Rietschel, M., Schulze, T., Greenwood, T., Schork, N., Gurling, H., Muglia, P., Upmanyu, R., Tozzi, F., Noethen, M., Wienker, T., Steffens, M., Nurnberger, J., Kendler, K., Riley, B., van den Oord, E., Boomsma, D., de Geus, E., Hoogendijk, W., Penninx, B., Willemsen, A. H. M., Posthuma, D., Coryell, W., Hamilton, S., Kloiber, S., Lucae, S., Ripke, S., Lawson, W. B., Lewis, C., McGuffin, P., Martin, N., Wray, N., McGrath, P., Weissman, M. M., Offord, J., Scheftner, W. A., Slager, S., Fanous, A., Hultman, C., Kivikko, S., Laurent, C., Lencz, T., Malhotra, A., Mowry, B., Holliday, E., Sanders, A., Schwab, S., Wildenaver, D., St. Clair, D., Dudbridge, F., Pickering, E., Posthuma, D., Sebat, J. & Tzeng, J. Y., May 2009, In : American Journal of Psychiatry. 166, 5, p. 540-556 17 p.

Research output: Contribution to journalReview article

308 Scopus citations

Genome-wide association study of bipolar disorder in European American and African American individuals

Smith, E. N., Bloss, C. S., Badner, J. A., Barrett, T., Belmonte, P. L., Berrettini, W., Byerley, W., Coryell, W., Craig, D., Edenberg, H. J., Eskin, E., Foroud, T., Gershon, E., Greenwood, T. A., Hipolito, M., Koller, D. L., Lawson, W. B., Liu, C., Lohoff, F., McInnis, M. G. & 17 others, McMahon, F. J., Mirel, D. B., Murray, S. S., Nievergelt, C., Nurnberger, J., Nwulia, E. A., Paschall, J., Potash, J. B., Rice, J., Schulze, T. G., Scheftner, W., Panganiban, C., Zaitlen, N., Zandi, P. P., Zöllner, S., Schork, N. J. & Kelsoe, J. R., Aug 1 2009, In : Molecular Psychiatry. 14, 8, p. 755-763 9 p.

Research output: Contribution to journalArticle

247 Scopus citations

Genome-wide linkage and follow-up association study of postpartum mood symptoms

NIMH Bipolar Disorder Genetics Initiative, the "Molecular Genetics of Schizophrenia II" (MGS-2) collaboration, Bipolar Genetics Studies (BiGS) Collaboration & NIMH Genetics of Recurrent Early-Onset Depression (GenRED) project, Nov 1 2009, In : American Journal of Psychiatry. 166, 11, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Identifying blood biomarkers for mood disorders using convergent functional genomics

Le-Niculescu, H., Kurian, S. M., Yehyawi, N., Dike, C., Patel, S. D., Edenberg, H. J., Tsuang, M. T., Salomon, D. R., Nurnberger, J. I. & Niculescu, A. B., Feb 2009, In : Molecular Psychiatry. 14, 2, p. 156-174 19 p.

Research output: Contribution to journalArticle

139 Scopus citations

New hope for pharmacogenetic testing

Nurnberger, J. I., Jun 1 2009, In : American Journal of Psychiatry. 166, 6, p. 635-638 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Premenstrual mood symptoms: Study of familiality and personality correlates in mood disorder pedigrees

NIMH Genetics Initiative Bipolar Disorder Consortium, Feb 1 2009, In : Archives of Women's Mental Health. 12, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Singleton deletions throughout the genome increase risk of bipolar disorder

Zhang, D., Cheng, L., Qian, Y., Alliey-Rodriguez, N., Kelsoe, J. R., Greenwood, T., Nievergelt, C., Barrett, T. B., McKinney, R., Schork, N., Smith, E. N., Bloss, C., Nurnberger, J., Edenberg, H. J., Foroud, T., Sheftner, W., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W. & 16 others, Rice, J., Byerley, W., McMahon, F., Schulze, T. G., Berrettini, W., Potash, J. B., Belmonte, P. L., Zandi, P. P., McInnis, M. G., Zöllner, S., Craig, D., Szelinger, S., Koller, D., Christian, S. L., Liu, C. & Gershon, E. S., Apr 1 2009, In : Molecular Psychiatry. 14, 4, p. 376-380 5 p.

Research output: Contribution to journalArticle

113 Scopus citations
2008

A Multimethod Investigation of the Behavioral Activation System in Bipolar Disorder

Hayden, E. P., Bodkins, M., Brenner, C., Shekhar, A., Nurnberger, J. I., O'Donnell, B. F. & Hetrick, W. P., Feb 2008, In : Journal of Abnormal Psychology. 117, 1, p. 164-170 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs

Ghosh, S., Bierut, L. J., Porjesz, B., Edenberg, H. J., Dick, D., Goate, A., Hesselbrock, V., Nurnberger, J., Foroud, T., Kramer, J., Rice, J. & Begleiter, H., Oct 5 2008, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 147, 7, p. 1301-1305 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

A regulatory variation in OPRK1, the gene encoding the κ-opioid receptor, is associated with alcohol dependence

Edenberg, H. J., Wang, J., Tian, H., Pochareddy, S., Xuei, X., Wetherill, L., Goate, A., Hinrichs, T., Kuperman, S., Nurnberger, J. I., Schuckit, M., Tischfield, J. A. & Foroud, T., Jun 15 2008, In : Human molecular genetics. 17, 12, p. 1783-1789 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence

Grucza, R. A., Wang, J. C., Stitzel, J. A., Hinrichs, A. L., Saccone, S. F., Saccone, N. L., Bucholz, K. K., Cloninger, C. R., Neuman, R. J., Budde, J. P., Fox, L., Bertelsen, S., Kramer, J., Hesselbrock, V., Tischfield, J., Nurnberger, J. I., Almasy, L., Porjesz, B., Kuperman, S., Schuckit, M. A. & 4 others, Edenberg, H. J., Rice, J. P., Goate, A. M. & Bierut, L. J., Dec 1 2008, In : Biological psychiatry. 64, 11, p. 922-929 8 p.

Research output: Contribution to journalArticle

102 Scopus citations

A simulated genetic structure for bipolar illness

Nurnberger, J. I., Sep 5 2008, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 147, 6, p. 952-956 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence

Xuei, X., Flury-Wetherill, L., Almasy, L., Bierut, L., Tischfield, J., Schuckit, M., Nurnberger, J. I., Foroud, T. & Edenberg, H. J., Mar 1 2008, In : Addiction Biology. 13, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Association of NFKB1, which encodes a subunit of the transcription factor NF-κB, with alcohol dependence

Edenberg, H. J., Xuei, X., Wetherill, L. F., Bierut, L., Bucholz, K., Dick, D. M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M. A., Tischfield, J. A., Almasy, L. A., Nurnberger, J. I. & Foroud, T., Apr 1 2008, In : Human molecular genetics. 17, 7, p. 963-970 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

Association study of Wnt signaling pathway genes in bipolar disorder

Zandi, P. P., Belmonte, P. L., Willour, V. L., Goes, F. S., Badner, J. A., Simpson, S. G., Gershon, E. S., McMahon, F. J., DePaulo, J. R., Potash, J. B., Steele, J., Pearl, J., Kassem, L., Lopez, V., MacKinnon, D., Miller, E., Toolan, J., Schulze, T., Byerley, W., Coryell, W. & 3 others, Kelsoe, J., Rice, J. & Nurnberger, J., Jul 1 2008, In : Archives of general psychiatry. 65, 7, p. 785-793 9 p.

Research output: Contribution to journalArticle

56 Scopus citations