John Nurnberger

  • Joyce & Iver Small Professor of Psychiatry, Psychiatry
  • 35058 Citations
  • 90 h-Index
1968 …2019
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Publications 1968 2019

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2019

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J. C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., Tischfield, J., Harari, O., Zeran, L., Hesselbrock, V., Bauer, L., Raj, T., Porjesz, B., Agrawal, A., Foroud, T., Edenberg, H. & 2 others, Mayfield, R. D. & Goate, A., Dec 1 2019, In : Translational psychiatry. 9, 1, 89.

Research output: Contribution to journalArticle

Alcoholism
Genome
Alcohol Drinking
Brain
Genes

A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults

Chan, G., Kramer, J. R., Schuckit, M. A., Hesselbrock, V., Bucholz, K. K., Edenberg, H., Acion, L., Langbehn, D., McCutcheon, V., Nurnberger, J., Hesselbrock, M., Porjesz, B., Bierut, L., Marenna, B. C., Cookman, A. & Kuperman, S., Jan 1 2019, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Drinking
Alcohols
Alcohol Drinking
Alcoholism
Medical problems
1 Citation (Scopus)

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

McCarthy, M. J., Wei, H., Nievergelt, C. M., Stautland, A., Maihofer, A. X., Welsh, D. K., Shilling, P., Alda, M., Alliey-Rodriguez, N., Anand, A., Andreasson, O. A., Balaraman, Y., Berrettini, W. H., Bertram, H., Brennand, K. J., Calabrese, J. R., Calkin, C. V., Claasen, A., Conroy, C., Coryell, W. H. & 42 others, Craig, D. W., D’Arcangelo, N., Demodena, A., Djurovic, S., Feeder, S., Fisher, C., Frazier, N., Frye, M. A., Gage, F. H., Gao, K., Garnham, J., Gershon, E. S., Glazer, K., Goes, F., Goto, T., Harrington, G., Jakobsen, P., Kamali, M., Karberg, E., Kelly, M., Leckband, S. G., Lohoff, F., McInnis, M. G., Mondimore, F., Morken, G., Nurnberger, J., Obral, S., Oedegaard, K. J., Ortiz, A., Ritchey, M., Ryan, K., Schinagle, M., Schoeyen, H., Schwebel, C., Shaw, M., Shekhtman, T., Slaney, C., Stapp, E., Szelinger, S., Tarwater, B., Zandi, P. P. & Kelsoe, J. R., Feb 1 2019, In : Neuropsychopharmacology. 44, 3, p. 620-628 9 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Bipolar Disorder
Lithium
Therapeutics
Sleep Initiation and Maintenance Disorders

Dr Nurnberger and Colleagues Reply

Nurnberger, J., Austin, J., Berrettini, W. H., Besterman, A. D., DeLisi, L. E., Grice, D. E., Kennedy, J. L., Moreno-De-Luca, D., Potash, J. B., Ross, D. A., Schulze, T. G. & Zai, G., Apr 9 2019, In : The Journal of clinical psychiatry. 80, 3

Research output: Contribution to journalArticle

Open Access

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 1 2019, In : European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Single Nucleotide Polymorphism
Haplotypes
Genes
Chromosomes, Human, Pair 15
1 Citation (Scopus)

Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement

Johnson, E. C., Tillman, R., Aliev, F., Meyers, J. L., Salvatore, J. E., Anokhin, A. P., Dick, D. M., Edenberg, H., Kramer, J. R., Kuperman, S., McCutcheon, V. V., Nurnberger, J., Porjesz, B., Schuckit, M. A., Tischfield, J., Bucholz, K. K. & Agrawal, A., Jan 1 2019, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Cannabis
Odds Ratio
Genome-Wide Association Study

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria

Lai, D., Wetherill, L., Bertelsen, S., Carey, C. E., Kamarajan, C., Kapoor, M., Meyers, J. L., Anokhin, A. P., Bennett, D. A., Bucholz, K. K., Chang, K. K., De Jager, P. L., Dick, D. M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Raj, T., Schuckit, M., Scott, D. M. & 9 others, Taylor, R. E., Tischfield, J., Hariri, A. R., Edenberg, H., Agrawal, A., Bogdan, R., Porjesz, B., Goate, A. M. & Foroud, T., Jul 1 2019, In : Genes, Brain and Behavior. 18, 6, e12579.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Diagnostic and Statistical Manual of Mental Disorders
Alcoholism
Drinking
Meta-Analysis

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Jan 1 2019, In : Addiction Biology. e12800.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alcoholism
Ethanol
Alcohols
Drinking
11 Citations (Scopus)

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Genome
Neurotransmitter Transport Proteins
Endocannabinoids

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H., Foroud, T., Bogdan, R. & Agrawal, A., Jan 1 2019, In : Genes, Brain and Behavior. e12580.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Reward
African Americans
Alcoholism
Substance-Related Disorders

Patterns and predictors of family environment among adolescents at high and low risk for familial bipolar disorder

Stapp, E. K., Musci, R. J., Fullerton, J. M., Glowinski, A. L., McInnis, M., Mitchell, P. B., Hulvershorn, L., Ghaziuddin, N., Roberts, G. M. P., Merikangas, K. R., Nurnberger, J. & Wilcox, H. C., Jul 1 2019, In : Journal of Psychiatric Research. 114, p. 153-160 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Mothers
Interviews
Conflict (Psychology)
Family Relations

Salivary melatonin onset in youth at familial risk for bipolar disorder

Bipolar High Risk Research Group, Apr 1 2019, In : Psychiatry Research. 274, p. 49-57 9 p.

Research output: Contribution to journalArticle

Melatonin
Bipolar Disorder
Light
Polysomnography
Saliva

The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample

Johnson, E. C., St. Pierre, C. L., Meyers, J. L., Aliev, F., McCutcheon, V. V., Lai, D., Dick, D. M., Goate, A. M., Kramer, J., Kuperman, S., Nurnberger, J., Schuckit, M. A., Porjesz, B., Edenberg, H., Bucholz, K. K. & Agrawal, A., Jun 1 2019, In : Alcoholism: Clinical and Experimental Research. 43, 6, p. 1113-1125 13 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Drinking
Alcohols
Alcoholism
Area Under Curve
2018

21st-Century Genetics in Psychiatric Residency Training: How Do We Get There?

Besterman, A. D., Moreno-De-Luca, D. & Nurnberger, J., Jan 1 2018, (Accepted/In press) In : JAMA Psychiatry.

Research output: Contribution to journalArticle

Internship and Residency
Psychiatry
6 Citations (Scopus)

A Biomarker Characterizing Neurodevelopment with applications in Autism

Wu, D., José, J. V., Nurnberger, J. & Torres, E. B., Dec 1 2018, In : Scientific Reports. 8, 1, 614.

Research output: Contribution to journalArticle

Autistic Disorder
Biomarkers
Electromagnetic Phenomena
Coordination Complexes
Neurosciences

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Jun 25 2018, In : BMC Genomics. 19, 1, 494.

Research output: Contribution to journalArticle

Genome-Wide Association Study

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D. & 32 others, Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In : International Journal of Bipolar Disorders. 6, 1, 24.

Research output: Contribution to journalArticle

Marketing
Bipolar Disorder
Genome-Wide Association Study
Genetic Research
Data Mining
1 Citation (Scopus)

Early-onset tobacco use and suicide-related behavior – A prospective study from adolescence to young adulthood

Korhonen, T., Sihvola, E., Latvala, A., Dick, D. M., Pulkkinen, L., Nurnberger, J., Rose, R. J. & Kaprio, J., Apr 1 2018, In : Addictive Behaviors. 79, p. 32-38 7 p.

Research output: Contribution to journalArticle

Tobacco
Tobacco Use
Suicide
Prospective Studies
Odds Ratio
4 Citations (Scopus)

Genome-wide association study identifies a novel locus for cannabis dependence

Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L. & 16 others, Farrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

Marijuana Abuse
Genome-Wide Association Study
Cannabis
Genome
Single Nucleotide Polymorphism
44 Citations (Scopus)

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, Jun 14 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

Dissection
Bipolar Disorder
Schizophrenia
Genes
Potassium

Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective

Su, J., Kuo, S. I. C., Aliev, F., Guy, M. C., Derlan, C. L., Edenberg, H., Nurnberger, J., Kramer, J. R., Bucholz, K. K., Salvatore, J. E. & Dick, D. M., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Parenting
Alcoholism
Alcohols
Fathers
Mothers
3 Citations (Scopus)

Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder

McLean, C. K., Narayan, S., Lin, S. Y., Rai, N., Chung, Y., Hipolito, M. M. S., Cascella, N. G., Nurnberger, J., Ishizuka, K., Sawa, A. S. & Nwulia, E. A., Dec 1 2018, In : Translational Psychiatry. 8, 1, 81.

Research output: Contribution to journalArticle

Bipolar Disorder
Lithium
Neurons
Therapeutics
Antimanic Agents
21 Citations (Scopus)

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Dec 1 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Alcoholism
Psychiatry
Genome
Drinking Behavior

What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics

Nurnberger, J., Austin, J., Berrettini, W. H., Besterman, A. D., DeLisi, L. E., Grice, D. E., Kennedy, J. L., Moreno-De-Luca, D., Potash, J. B., Ross, D. A., Schulze, T. G. & Zai, G., Nov 27 2018, In : The Journal of clinical psychiatry. 80, 1

Research output: Contribution to journalArticle

Internship and Residency
Psychiatry
Education
Committee Membership
Exome
2017
1 Citation (Scopus)

A GABRA2 polymorphism improves a model for prediction of drinking initiation

Kuperman, S., Chan, G., Kramer, J., Wetherill, L., Acion, L., Edenberg, H., Foroud, T., Nurnberger, J., Agrawal, A., Anokhin, A., Brooks, A., Hesselbrock, V., Hesselbrock, M., Schuckit, M., Tischfield, J. & Liu, X., Sep 1 2017, In : Alcohol. 63, p. 1-8 8 p.

Research output: Contribution to journalArticle

Polymorphism
Drinking
Genotype
Self Report
Single Nucleotide Polymorphism
1 Citation (Scopus)

Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families

Mccutcheon, V. V., Agrawal, A., Kuo, S. I. C., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H., Nurnberger, J., Kramer, J. R., Kuperman, S., Schuckit, M. A., Hesselbrock, V. M., Brooks, A., Porjesz, B. & Bucholz, K. K., 2017, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Cannabis
Tobacco Products
Alcohols
Parents
Tobacco Use
62 Citations (Scopus)

Autism genetics: opportunities and challenges for clinical translation

Vorstman, J. A. S., Parr, J. R., Moreno-De-Luca, D., Anney, R. J. L., Nurnberger, J. & Hallmayer, J. F., Mar 6 2017, (Accepted/In press) In : Nature Reviews Genetics.

Research output: Contribution to journalArticle

Autistic Disorder
Genetic Pleiotropy
Penetrance
Protein Biosynthesis
Research
59 Citations (Scopus)

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J. J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., van der Auwera, S., Wainwright, N., Wang, J. C., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J., Breslau, N. & Bierut, L. J., Apr 4 2017, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Meta-Analysis
Genotype
Depression
Alleles
Serotonin Plasma Membrane Transport Proteins
10 Citations (Scopus)

Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study

Bucholz, K. K., McCutcheon, V. V., Agrawal, A., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J., Salvatore, J. E., Schuckit, M. A., Bierut, L. J., Foroud, T., Chan, G., Hesselbrock, M., Meyers, J. L., Edenberg, H. & Porjesz, B., Feb 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 2, p. 359-368 10 p.

Research output: Contribution to journalArticle

Cannabis
Psychiatry
Alcohols
Prospective Studies
Wounds and Injuries
19 Citations (Scopus)

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In : Biological Psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Attention Deficit Disorder with Hyperactivity
Bipolar Disorder
Meta-Analysis
Nucleotides
14 Citations (Scopus)

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

Alcoholism
Ethanol
Genes
Alcohols
Long Noncoding RNA
27 Citations (Scopus)

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

Borderline Personality Disorder
Genome-Wide Association Study
Bipolar Disorder
Schizophrenia
Depression
31 Citations (Scopus)

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, Walsh, C. A., Wallace, S., Vorstman, J. A. S., Vieland, V. J., Vicente, A. M., Vanengeland, H., Tsang, K., Thompson, A. P., Szatmari, P., Svantesson, O., Steinberg, S., Stefansson, K., Stefansson, H., State, M. W., Soorya, L., Silagadze, T., Scherer, S. W., Schellenberg, G. D., Sandin, S., Sanders, S. J., Saemundsen, E., Rouleau, G. A., Rogé, B., Roeder, K., Roberts, W., Reichert, J., Reichenberg, A., Rehnström, K., Regan, R., Poustka, F., Poultney, C. S., Piven, J., Pinto, D., Pericak-Vance, M. A., Pejovic-Milovancevic, M., Pedersen, M. G., Pedersen, C. B., Paterson, A. D., Parr, J. R., Pagnamenta, A. T., Oliveira, G., Nurnberger, J., Nordentoft, M., Murtha, M. T., Mouga, S., Mortensen, P. B., Mors, O., Morrow, E. M., Moreno-De-Luca, D., Monaco, A. P., Minshew, N., Merikangas, A., McMahon, W. M., McGrew, S. G., Mattheisen, M., Martsenkovsky, I., Martin, D. M., Mane, S. M., Magnusson, P., Magalhaes, T., Maestrini, E., Lowe, J. K., Lord, C., Levitt, P., Martin, C. L., Ledbetter, D. H., Leboyer, M., Lecouteur, A. S., Ladd-Acosta, C., Kolevzon, A., Klauck, S. M., Jacob, S., Iliadou, B., Hultman, C. M., Hougaard, D. M., Hertz-Picciotto, I., Hendren, R., Hansen, C. S., Haines, J. L., Guter, S. J., Grice, D. E., Green, J. M., Green, A., Goldberg, A. P., Gillberg, C., Gilbert, J., Gallagher, L., Freitag, C. M., Fombonne, E., Folstein, S. E., Fernandez, B., Fallin, M. D., Ercan-Sencicek, A. G., Ennis, S., Duque, F., Duketis, E., Delorme, R., Derubeis, S., Dejonge, M. V., Dawson, G., Cuccaro, M. L., Correia, C. T., Conroy, J., Conceição, I. C., Chiocchetti, A. G., Celestino-Soper, P. B. S., Casey, J., Cantor, R. M., Café, C., Bybjerg-Grauholm, J., Brennan, S., Bourgeron, T., Bolton, P. F., Bölte, S., Bolshakova, N., Betancur, C., Bernier, R., Beaudet, A. L., Battaglia, A., Bal, V. H., Baird, G., Bailey, A. J., Bækvad-Hansen, M., Bader, J. S., Bacchelli, E., Anagnostou, E., Amaral, D., Almeida, J., Børglum, A. D., Buxbaum, J. D., Chakravarti, A., Cook, E. H., Coon, H., Geschwind, D. H., Gill, M., Hallmayer, J., Palotie, A., Santangelo, S., Sutcliffe, J. S., Arking, D. E., Devlin, B., Daly, M. J. & Hakonarson, H., May 22 2017, In : Molecular Autism. 8, 1, 21.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Meta-Analysis
Schizophrenia
Genome
Genomics
14 Citations (Scopus)

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H., Nurnberger, J., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA Psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Alcoholism
Genome-Wide Association Study
Veterans
Meta-Analysis
83 Citations (Scopus)

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

Psychiatric Genomics Consortium Autism Group & iPSYCH-Broad Autism Group, Jul 1 2017, In : Nature Genetics. 49, 7, p. 978-985 8 p.

Research output: Contribution to journalArticle

Autism Spectrum Disorder
Schizophrenia
Phenotype
4 Citations (Scopus)

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

Agrawal, A., Tillman, R., Grucza, R. A., Nelson, E. C., McCutcheon, V. V., Few, L., Conner, K. R., Lynskey, M. T., Dick, D. M., Edenberg, H., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J., Schuckit, M. A., Porjesz, B. & Bucholz, K. K., Apr 15 2017, In : Journal of Affective Disorders. 213, p. 96-104 9 p.

Research output: Contribution to journalArticle

Suicidal Ideation
Suicide
Alcoholism
Substance-Related Disorders
Marijuana Abuse
1 Citation (Scopus)

Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?

Hulvershorn, L., King, J., Monahan, P., Wilcox, H. C., Mitchell, P. B., Fullerton, J. M., Edenberg, H., Roberts, G. M. P., Kamali, M., Glowinski, A. L., Ghaziuddin, N., McInnis, M., Iyer-Eimerbrink, P. A. & Nurnberger, J., Oct 1 2017, In : Comprehensive Psychiatry. 78, p. 130-139 10 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Substance-Related Disorders
Young Adult
Drive
Diagnostic and Statistical Manual of Mental Disorders
9 Citations (Scopus)
Drinking
Trajectories
Alcohols
Genes
Alcoholism
3 Citations (Scopus)

Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts

Wilcox, H. C., Fullerton, J. M., Glowinski, A. L., Benke, K., Kamali, M., Hulvershorn, L., Stapp, E. K., Edenberg, H., Roberts, G. M. P., Ghaziuddin, N., Fisher, C., Brucksch, C., Frankland, A., Toma, C., Shaw, A. D., Kastelic, E., Miller, L., McInnis, M. G., Mitchell, P. B. & Nurnberger, J., Dec 1 2017, In : Journal of the American Academy of Child and Adolescent Psychiatry. 56, 12, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Suicide
Substance-Related Disorders
Demography
Wounds and Injuries
2 Citations (Scopus)
Chromatin Assembly and Disassembly
Alcoholism
Chromatin
Sucrose
Alcohols
2016
18 Citations (Scopus)

A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region

Bipolar Genome Study (BiGS), Jan 1 2016, In : Journal of Affective Disorders. 189, p. 141-149 9 p., 7712.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Comorbidity
Genome
Mood Disorders
34 Citations (Scopus)

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

Schwantes-An, T. H., Zhang, J., Chen, L. S., Hartz, S. M., Culverhouse, R. C., Chen, X., Coon, H., Frank, J., Kamens, H. M., Konte, B., Kovanen, L., Latvala, A., Legrand, L. N., Maher, B. S., Melroy, W. E., Nelson, E. C., Reid, M. W., Robinson, J. D., Shen, P. H., Yang, B. Z. & 90 others, Andrews, J. A., Aveyard, P., Beltcheva, O., Brown, S. A., Cannon, D. S., Cichon, S., Corley, R. P., Dahmen, N., Degenhardt, L., Foroud, T., Gaebel, W., Giegling, I., Glatt, S. J., Grucza, R. A., Hardin, J., Hartmann, A. M., Heath, A. C., Herms, S., Hodgkinson, C. A., Hoffmann, P., Hops, H., Huizinga, D., Ising, M., Johnson, E. O., Johnstone, E., Kaneva, R. P., Kendler, K. S., Kiefer, F., Kranzler, H. R., Krauter, K. S., Levran, O., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Martin, N. G., Mattheisen, M., Montgomery, G. W., Müller-Myhsok, B., Murphy, M. F., Neale, M. C., Nikolov, M. A., Nishita, D., Nöthen, M. M., Nurnberger, J., Partonen, T., Pergadia, M. L., Reynolds, M., Ridinger, M., Rose, R. J., Rouvinen-Lagerström, N., Scherbaum, N., Schmäl, C., Soyka, M., Stallings, M. C., Steffens, M., Treutlein, J., Tsuang, M., Wall, T. L., Wodarz, N., Yuferov, V., Zill, P., Bergen, A. W., Chen, J., Cinciripini, P. M., Edenberg, H., Ehringer, M. A., Ferrell, R. E., Gelernter, J., Goldman, D., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Kaprio, J., Kreek, M. J., Kremensky, I. M., Madden, P. A. F., McGue, M., Munafò, M. R., Philibert, R. A., Rietschel, M., Roy, A., Rujescu, D., Saarikoski, S. T., Swan, G. E., Todorov, A. A., Vanyukov, M. M., Weiss, R. B., Bierut, L. J. & Saccone, N. L., Mar 1 2016, In : Behavior Genetics. 46, 2, p. 151-169 19 p.

Research output: Contribution to journalArticle

substance abuse
meta-analysis
liability
ancestry
Substance-Related Disorders
4 Citations (Scopus)

CYP2A6 metabolism in the development of smoking behaviors in young adults

Olfson, E., Bloom, J., Bertelsen, S., Budde, J. P., Breslau, N., Brooks, A., Culverhouse, R., Chan, G., Chen, L. S., Chorlian, D., Dick, D. M., Edenberg, H., Hartz, S., Hatsukami, D., Hesselbrock, V. M., Johnson, E. O., Kramer, J. R., Kuperman, S., Meyers, J. L., Nurnberger, J. & 8 others, Porjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J., 2016, (Accepted/In press) In : Addiction Biology.

Research output: Contribution to journalArticle

Tobacco Use Disorder
Cytochrome P-450 Enzyme System
Young Adult
Smoking
Nicotine

Diagnostic Interview for Genetic Studies: validity and reliability of the Croatian version

Kralj, Ž., Dedić, M., Kovačević, A., Malički, M., Dedić, J., Pelivan, M., Vuković, D., Fisher, C., Kember, R. L., Nurnberger, J., Bućan, M. & Britvić, D., Oct 21 2016, (Accepted/In press) In : Psychiatric Genetics.

Research output: Contribution to journalArticle

Reproducibility of Results
Interviews
Mentally Ill Persons
Croatia
Aptitude
2 Citations (Scopus)

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder (Nature (2015) 527 (95-99) DOI: 10.1038/nature15526)

Mertens, J., Wang, Q. W., Kim, Y., Yu, D. X., Pham, S., Yang, B., Zheng, Y., Diffenderfer, K. E., Zhang, J., Soltani, S., Eames, T., Schafer, S. T., Boyer, L., Marchetto, M. C., Nurnberger, J., Calabrese, J. R., Oedegaard, K. J., McCarthy, M. J., Zandi, P. P., Alda, M. & 6 others, Nievergelt, C. M., Mi, S., Brennand, K. J., Kelsoe, J. R., Gage, F. H. & Yao, J., Feb 11 2016, In : Nature. 530, 7589, p. 242 1 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Interactions between alcohol metabolism genes and religious involvement in association with maximum drinks and alcohol dependence symptoms

Chartier, K. G., Dick, D. M., Almasy, L., Chan, G., Aliev, F., Schuckit, M. A., Scott, D. M., Kramer, J., Bucholz, K. K., Bierut, L. J., Nurnberger, J., Porjesz, B. & Hesselbrock, V. M., May 1 2016, In : Journal of Studies on Alcohol and Drugs. 77, 3, p. 393-404 12 p.

Research output: Contribution to journalArticle

Metabolism
Alcoholism
Genes
alcohol
Alcohols
4 Citations (Scopus)

Interhemispheric white matter integrity in young people with bipolar disorder and at high genetic risk

Roberts, G., Wen, W., Frankland, A., Perich, T., Holmes-Preston, E., Levy, F., Lenroot, R. K., Hadzi-Pavlovic, D., Nurnberger, J., Breakspear, M. & Mitchell, P. B., Aug 1 2016, In : Psychological Medicine. 46, 11, p. 2385-2396 12 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Corpus Callosum
Major Depressive Disorder
Anisotropy
White Matter
8 Citations (Scopus)

Risk factors for suicide in bipolar i disorder in two prospectively studied cohorts

Coryell, W., Kriener, A., Butcher, B., Nurnberger, J., McMahon, F., Berrettini, W. & Fiedorowicz, J., Jan 15 2016, In : Journal of Affective Disorders. 190, p. 1-5 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Suicide
Depression
Odds Ratio
National Institute of Mental Health (U.S.)
19 Citations (Scopus)

The Pharmacogenomics of Bipolar Disorder study (PGBD): Identification of genes for lithium response in a prospective sample

Oedegaard, K. J., Alda, M., Anand, A., Andreassen, O. A., Balaraman, Y., Berrettini, W. H., Bhattacharjee, A., Brennand, K. J., Burdick, K. E., Calabrese, J. R., Calkin, C. V., Claasen, A., Coryell, W. H., Craig, D., DeModena, A., Frye, M., Gage, F. H., Gao, K., Garnham, J., Gershon, E. & 18 others, Jakobsen, P., Leckband, S. G., McCarthy, M. J., McInnis, M. G., Maihofer, A. X., Mertens, J., Morken, G., Nievergelt, C. M., Nurnberger, J., Pham, S., Schoeyen, H., Shekhtman, T., Shilling, P. D., Szelinger, S., Tarwater, B., Yao, J., Zandi, P. P. & Kelsoe, J. R., May 5 2016, In : BMC Psychiatry. 16, 1, 129.

Research output: Contribution to journalArticle

Pharmacogenetics
Bipolar Disorder
Lithium
Genes
Genome-Wide Association Study
30 Citations (Scopus)

Toward precision psychiatry: Statistical platform for the personalized characterization of natural behaviors

Torres, E. B., Isenhower, R. W., Nguyen, J., Whyatt, C., Nurnberger, J., Jose, J. V., Silverstein, S. M., Papathomas, T. V., Sage, J. & Cole, J., Feb 2 2016, In : Frontiers in Neurology. 7, FEB, 8.

Research output: Contribution to journalArticle

Nervous System Diseases
Psychiatry
Behavioral Sciences
Numismatics
Brain Diseases