John Nurnberger

  • Joyce & Iver Small Professor of Psychiatry, Psychiatry
  • 38321 Citations
  • 94 h-Index
1968 …2020

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Publications

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Article
2020

A Family-Based Genome Wide Association Study of Externalizing Behaviors

Barr, P. B., Salvatore, J. E., Wetherill, L., Anokhin, A., Chan, G., Edenberg, H. J., Kuperman, S., Meyers, J., Nurnberger, J., Porjesz, B., Schuckit, M. & Dick, D. M., May 1 2020, In : Behavior Genetics. 50, 3, p. 175-183 9 p.

Research output: Contribution to journalArticle

A randomized proof-of-mechanism trial applying the ‘fast-fail’ approach to evaluating κ-opioid antagonism as a treatment for anhedonia

Krystal, A. D., Pizzagalli, D. A., Smoski, M., Mathew, S. J., Nurnberger, J., Lisanby, S. H., Iosifescu, D., Murrough, J. W., Yang, H., Weiner, R. D., Calabrese, J. R., Sanacora, G., Hermes, G., Keefe, R. S. E., Song, A., Goodman, W., Szabo, S. T., Whitton, A. E., Gao, K. & Potter, W. Z., May 1 2020, In : Nature Medicine. 26, 5, p. 760-768 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations

Lai, D., Kapoor, M., Wetherill, L., Schwandt, M., Ramchandani, V. A., Goldman, D., Chao, M., Almasy, L., Bucholz, K., Hart, R. P., Kamarajan, C., Meyers, J. L., Nurnberger, J. I., Tischfield, J., Edenberg, H. J., Schuckit, M., Goate, A., Scott, D. M., Porjesz, B., Agrawal, A. & 1 others, Foroud, T., 2020, (Accepted/In press) In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

Research output: Contribution to journalArticle

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. J. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Mar 1 2020, In : Addiction Biology. 25, 2, e12800.

Research output: Contribution to journalArticle

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 332 others, Hanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacos Mayora, M., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Nacmias, B., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op't Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Grove, J., Henders, A. K., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Mortensen, P. B., Polimanti, R., McClintick, J. N., Adkins, A. E., Aliev, F., Bacanu, S. A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L. S., Clarke, T. K., Degenhardt, F., Docherty, A. R., Edwards, A. C., Foo, J. C., Fox, L., Frank, J., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Hodgkinson, C., Hoffmann, P., Hottenga, J. J., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Peterson, R. E., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J. C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Zhou, H., Boardman, J. D., Chen, D., Choi, D. S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Frye, M. A., Gäbel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Koller, G., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S. H., Wodarz, N., Zill, P., Adkins, D. E., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Costello, E. J., de Wit, H., Diazgranados, N., Eriksson, J. G., Farrer, L. A., Foroud, T. M., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Johnson, E. O., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P. K. E., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R. J., Shen, P. H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Wade, T. D., Heath, A. C., Montgomery, G. W., Martin, N. G., Sullivan, P. F., Kaprio, J., Breen, G., Gelernter, J., Edenberg, H. J., Bulik, C. M. & Agrawal, A., 2020, (Accepted/In press) In : Addiction Biology. e12880.

Research output: Contribution to journalArticle

The association between lithium use and neurocognitive performance in patients with bipolar disorder

Burdick, K. E., Millett, C. E., Russo, M., Alda, M., Alliey-Rodriguez, N., Anand, A., Balaraman, Y., Berrettini, W., Bertram, H., Calabrese, J. R., Calkin, C., Conroy, C., Coryell, W., DeModena, A., Feeder, S., Fisher, C., Frazier, N., Frye, M., Gao, K., Garnham, J. & 30 others, Gershon, E. S., Glazer, K., Goes, F. S., Goto, T., Harrington, G. J., Jakobsen, P., Kamali, M., Kelly, M., Leckband, S., Løberg, E. M., Lohoff, F. W., Maihofer, A. X., McCarthy, M. J., McInnis, M., Morken, G., Nievergelt, C. M., Nurnberger, J., Oedegaard, K. J., Ortiz, A., Ritchey, M., Ryan, K., Schinagle, M., Schwebel, C., Shaw, M., Shilling, P., Slaney, C., Stapp, E., Tarwater, B., Zandi, P. & Kelsoe, J. R., 2020, (Accepted/In press) In : Neuropsychopharmacology.

Research output: Contribution to journalArticle

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2020, In : Biological psychiatry. 88, 2, p. 169-184 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk

Cho, S. B., Smith, R. L., Bucholz, K., Chan, G., Edenberg, H. J., Hesselbrock, V., Kramer, J., Mccutcheon, V. V., Nurnberger, J., Schuckit, M., Zang, Y., Dick, D. M. & Salvatore, J. E., 2020, (Accepted/In press) In : Development and Psychopathology.

Research output: Contribution to journalArticle

Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples

Barr, P. B., Ksinan, A., Su, J., Johnson, E. C., Meyers, J. L., Wetherill, L., Latvala, A., Aliev, F., Chan, G., Kuperman, S., Nurnberger, J., Kamarajan, C., Anokhin, A., Agrawal, A., Rose, R. J., Edenberg, H. J., Schuckit, M., Kaprio, J. & Dick, D. M., Dec 1 2020, In : Translational psychiatry. 10, 1, 196.

Research output: Contribution to journalArticle

Open Access
2019

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J. C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., Tischfield, J., Harari, O., Zeran, L., Hesselbrock, V., Bauer, L., Raj, T., Porjesz, B., Agrawal, A., Foroud, T., Edenberg, H. J. & 2 others, Mayfield, R. D. & Goate, A., Dec 1 2019, In : Translational psychiatry. 9, 1, 89.

Research output: Contribution to journalArticle

8 Scopus citations

A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults

Chan, G., Kramer, J. R., Schuckit, M. A., Hesselbrock, V., Bucholz, K. K., Edenberg, H. J., Acion, L., Langbehn, D., McCutcheon, V., Nurnberger, J. I., Hesselbrock, M., Porjesz, B., Bierut, L., Marenna, B. C., Cookman, A. & Kuperman, S., 2019, In : Alcoholism: Clinical and Experimental Research. 43, 8, p. 1759-1768 10 p.

Research output: Contribution to journalArticle

Association of polygenic liability for alcohol dependence and EEG connectivity in adolescence and young adulthood

Meyers, J. L., Chorlian, D. B., Johnson, E. C., Pandey, A. K., Kamarajan, C., Salvatore, J. E., Aliev, F., de Viteri, S. S. S., Zhang, J., Chao, M., Kapoor, M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Tischfield, J., Goate, A., Foroud, T., Dick, D. M., Edenberg, H. J. & 2 others, Agrawal, A. & Porjesz, B., Oct 2019, In : Brain Sciences. 9, 10, 280.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

McCarthy, M. J., Wei, H., Nievergelt, C. M., Stautland, A., Maihofer, A. X., Welsh, D. K., Shilling, P., Alda, M., Alliey-Rodriguez, N., Anand, A., Andreasson, O. A., Balaraman, Y., Berrettini, W. H., Bertram, H., Brennand, K. J., Calabrese, J. R., Calkin, C. V., Claasen, A., Conroy, C., Coryell, W. H. & 42 others, Craig, D. W., D’Arcangelo, N., Demodena, A., Djurovic, S., Feeder, S., Fisher, C., Frazier, N., Frye, M. A., Gage, F. H., Gao, K., Garnham, J., Gershon, E. S., Glazer, K., Goes, F., Goto, T., Harrington, G., Jakobsen, P., Kamali, M., Karberg, E., Kelly, M., Leckband, S. G., Lohoff, F., McInnis, M. G., Mondimore, F., Morken, G., Nurnberger, J. I., Obral, S., Oedegaard, K. J., Ortiz, A., Ritchey, M., Ryan, K., Schinagle, M., Schoeyen, H., Schwebel, C., Shaw, M., Shekhtman, T., Slaney, C., Stapp, E., Szelinger, S., Tarwater, B., Zandi, P. P. & Kelsoe, J. R., Feb 1 2019, In : Neuropsychopharmacology. 44, 3, p. 620-628 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H. J., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 2019, In : European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement

Johnson, E. C., Tillman, R., Aliev, F., Meyers, J. L., Salvatore, J. E., Anokhin, A. P., Dick, D. M., Edenberg, H. J., Kramer, J. R., Kuperman, S., McCutcheon, V. V., Nurnberger, J. I., Porjesz, B., Schuckit, M. A., Tischfield, J., Bucholz, K. K. & Agrawal, A., Apr 2019, In : Addiction. 114, 4, p. 687-697 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria

Lai, D., Wetherill, L., Bertelsen, S., Carey, C. E., Kamarajan, C., Kapoor, M., Meyers, J. L., Anokhin, A. P., Bennett, D. A., Bucholz, K. K., Chang, K. K., De Jager, P. L., Dick, D. M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Raj, T., Schuckit, M., Scott, D. M. & 9 others, Taylor, R. E., Tischfield, J., Hariri, A. R., Edenberg, H. J., Agrawal, A., Bogdan, R., Porjesz, B., Goate, A. M. & Foroud, T., Jul 2019, In : Genes, Brain and Behavior. 18, 6, e12579.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J. I., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H. J., Foroud, T., Bogdan, R. & Agrawal, A., Jul 2019, In : Genes, Brain and Behavior. 18, 6, e12580.

Research output: Contribution to journalArticle

1 Scopus citations

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Wellcome Trust Case-Control Consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, 23andMe Research Team & Psychosis Endophenotypes International Consortium, Dec 12 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to journalArticle

22 Scopus citations
Open Access
1 Scopus citations

Patterns and predictors of family environment among adolescents at high and low risk for familial bipolar disorder

Stapp, E. K., Musci, R. J., Fullerton, J. M., Glowinski, A. L., McInnis, M., Mitchell, P. B., Hulvershorn, L. A., Ghaziuddin, N., Roberts, G. M. P., Merikangas, K. R., Nurnberger, J. I. & Wilcox, H. C., Jul 2019, In : Journal of Psychiatric Research. 114, p. 153-160 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Salivary melatonin onset in youth at familial risk for bipolar disorder

Bipolar High Risk Research Group, Apr 2019, In : Psychiatry Research. 274, p. 49-57 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample

Johnson, E. C., St. Pierre, C. L., Meyers, J. L., Aliev, F., McCutcheon, V. V., Lai, D., Dick, D. M., Goate, A. M., Kramer, J., Kuperman, S., Nurnberger, J. I., Schuckit, M. A., Porjesz, B., Edenberg, H. J., Bucholz, K. K. & Agrawal, A., Jun 2019, In : Alcoholism: Clinical and Experimental Research. 43, 6, p. 1113-1125 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

21st-Century Genetics in Psychiatric Residency Training: How Do We Get There?

Besterman, A. D., Moreno-De-Luca, D. & Nurnberger, J., Jan 1 2018, (Accepted/In press) In : JAMA Psychiatry.

Research output: Contribution to journalArticle

2 Scopus citations

A Biomarker Characterizing Neurodevelopment with applications in Autism

Wu, D., José, J. V., Nurnberger, J. I. & Torres, E. B., Dec 1 2018, In : Scientific reports. 8, 1, 614.

Research output: Contribution to journalArticle

14 Scopus citations

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Jun 25 2018, In : BMC genomics. 19, 1, 494.

Research output: Contribution to journalArticle

3 Scopus citations

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Dec 1 2018, In : Communications Biology. 1, 1, 163.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families

McCutcheon, V. V., Agrawal, A., Kuo, S. I. C., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H. J., Nurnberger, J. I., Kramer, J. R., Kuperman, S., Schuckit, M. A., Hesselbrock, V. M., Brooks, A., Porjesz, B. & Bucholz, K. K., Feb 1 2018, In : Addiction. 113, 2, p. 336-345 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Collaborative meta-Analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J. J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van Der Auwera, S., Wainwright, N., Wang, J. C., Willemsen, G., Anderson, I. M., Arolt, V., Aslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., De Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J. I., Breslau, N. & Bierut, L. J., Jan 1 2018, In : Molecular Psychiatry. 23, 1, p. 133-142 10 p.

Research output: Contribution to journalArticle

104 Scopus citations

CYP2A6 metabolism in the development of smoking behaviors in young adults

Olfson, E., Bloom, J., Bertelsen, S., Budde, J. P., Breslau, N., Brooks, A., Culverhouse, R., Chan, G., Chen, L. S., Chorlian, D., Dick, D. M., Edenberg, H. J., Hartz, S., Hatsukami, D., Hesselbrock, V. M., Johnson, E. O., Kramer, J. R., Kuperman, S., Meyers, J. L., Nurnberger, J. & 8 others, Porjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J., Jan 2018, In : Addiction Biology. 23, 1, p. 437-447 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D. & 32 others, Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In : International Journal of Bipolar Disorders. 6, 1, 24.

Research output: Contribution to journalArticle

2 Scopus citations

Early-onset tobacco use and suicide-related behavior – A prospective study from adolescence to young adulthood

Korhonen, T., Sihvola, E., Latvala, A., Dick, D. M., Pulkkinen, L., Nurnberger, J., Rose, R. J. & Kaprio, J., Apr 2018, In : Addictive Behaviors. 79, p. 32-38 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Genome-wide association study identifies a novel locus for cannabis dependence

Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L. & 16 others, Farrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, Jun 14 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

121 Scopus citations

Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective

Su, J., Kuo, S. I. C., Aliev, F., Guy, M. C., Derlan, C. L., Edenberg, H. J., Nurnberger, J. I., Kramer, J. R., Bucholz, K. K., Salvatore, J. E. & Dick, D. M., Sep 2018, In : Alcoholism: Clinical and Experimental Research. 42, 9, p. 1783-1794 12 p.

Research output: Contribution to journalArticle

Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder

McLean, C. K., Narayan, S., Lin, S. Y., Rai, N., Chung, Y., Hipolito, M. M. S., Cascella, N. G., Nurnberger, J. I., Ishizuka, K., Sawa, A. S. & Nwulia, E. A., Dec 1 2018, In : Translational psychiatry. 8, 1, 81.

Research output: Contribution to journalArticle

3 Scopus citations

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Dec 1 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations
2017

A GABRA2 polymorphism improves a model for prediction of drinking initiation

Kuperman, S., Chan, G., Kramer, J., Wetherill, L., Acion, L., Edenberg, H. J., Foroud, T. M., Nurnberger, J., Agrawal, A., Anokhin, A., Brooks, A., Hesselbrock, V., Hesselbrock, M., Schuckit, M., Tischfield, J. & Liu, X., Sep 2017, In : Alcohol. 63, p. 1-8 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

A genome wide association study of fast beta EEG in families of European ancestry

Meyers, J. L., Zhang, J., Manz, N., Rangaswamy, M., Kamarajan, C., Wetherill, L., Chorlian, D. B., Kang, S. J., Bauer, L., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Tischfield, J., Wang, J. C., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B., May 1 2017, In : International Journal of Psychophysiology. 115, p. 74-85 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study

Bucholz, K. K., McCutcheon, V. V., Agrawal, A., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J. I., Salvatore, J. E., Schuckit, M. A., Bierut, L. J., Foroud, T. M., Chan, G., Hesselbrock, M., Meyers, J. L., Edenberg, H. J. & Porjesz, B., Feb 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 2, p. 359-368 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Diagnostic Interview for Genetic Studies: Validity and reliability of the Croatian version

Kralj, A., Dedić, M., Kovačević, A., Malički, M., Dedić, J., Pelivan, M., Vuković, D., Fisher, C., Kember, R. L., Nurnberger, J., Bućan, M. & Britvić, D., Jan 1 2017, In : Psychiatric genetics. 27, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In : Biological psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

43 Scopus citations

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, Walsh, C. A., Wallace, S., Vorstman, J. A. S., Vieland, V. J., Vicente, A. M., Vanengeland, H., Tsang, K., Thompson, A. P., Szatmari, P., Svantesson, O., Steinberg, S., Stefansson, K., Stefansson, H., State, M. W., Soorya, L., Silagadze, T., Scherer, S. W., Schellenberg, G. D., Sandin, S., Sanders, S. J., Saemundsen, E., Rouleau, G. A., Rogé, B., Roeder, K., Roberts, W., Reichert, J., Reichenberg, A., Rehnström, K., Regan, R., Poustka, F., Poultney, C. S., Piven, J., Pinto, D., Pericak-Vance, M. A., Pejovic-Milovancevic, M., Pedersen, M. G., Pedersen, C. B., Paterson, A. D., Parr, J. R., Pagnamenta, A. T., Oliveira, G., Nurnberger, J. I., Nordentoft, M., Murtha, M. T., Mouga, S., Mortensen, P. B., Mors, O., Morrow, E. M., Moreno-De-Luca, D., Monaco, A. P., Minshew, N., Merikangas, A., McMahon, W. M., McGrew, S. G., Mattheisen, M., Martsenkovsky, I., Martin, D. M., Mane, S. M., Magnusson, P., Magalhaes, T., Maestrini, E., Lowe, J. K., Lord, C., Levitt, P., Martin, C. L., Ledbetter, D. H., Leboyer, M., Lecouteur, A. S., Ladd-Acosta, C., Kolevzon, A., Klauck, S. M., Jacob, S., Iliadou, B., Hultman, C. M., Hougaard, D. M., Hertz-Picciotto, I., Hendren, R., Hansen, C. S., Haines, J. L., Guter, S. J., Grice, D. E., Green, J. M., Green, A., Goldberg, A. P., Gillberg, C., Gilbert, J., Gallagher, L., Freitag, C. M., Fombonne, E., Folstein, S. E., Fernandez, B., Fallin, M. D., Ercan-Sencicek, A. G., Ennis, S., Duque, F., Duketis, E., Delorme, R., Derubeis, S., Dejonge, M. V., Dawson, G., Cuccaro, M. L., Correia, C. T., Conroy, J., Conceição, I. C., Chiocchetti, A. G., Celestino-Soper, P. B. S., Casey, J., Cantor, R. M., Café, C., Bybjerg-Grauholm, J., Brennan, S., Bourgeron, T., Bolton, P. F., Bölte, S., Bolshakova, N., Betancur, C., Bernier, R., Beaudet, A. L., Battaglia, A., Bal, V. H., Baird, G., Bailey, A. J., Bækvad-Hansen, M., Bader, J. S., Bacchelli, E., Anagnostou, E., Amaral, D., Almeida, J., Børglum, A. D., Buxbaum, J. D., Chakravarti, A., Cook, E. H., Coon, H., Geschwind, D. H., Gill, M., Hallmayer, J., Palotie, A., Santangelo, S., Sutcliffe, J. S., Arking, D. E., Devlin, B., Daly, M. J. & Hakonarson, H., May 22 2017, In : Molecular Autism. 8, 1, 21.

Research output: Contribution to journalArticle

42 Scopus citations

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T. M., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

Psychiatric Genomics Consortium Autism Group & iPSYCH-Broad Autism Group, Jul 1 2017, In : Nature genetics. 49, 7, p. 978-985 8 p.

Research output: Contribution to journalArticle

134 Scopus citations

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

Agrawal, A., Tillman, R., Grucza, R. A., Nelson, E. C., McCutcheon, V. V., Few, L., Conner, K. R., Lynskey, M. T., Dick, D. M., Edenberg, H. J., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J. I., Schuckit, M. A., Porjesz, B. & Bucholz, K. K., Apr 15 2017, In : Journal of Affective Disorders. 213, p. 96-104 9 p.

Research output: Contribution to journalArticle

8 Scopus citations