John Nurnberger

  • Joyce & Iver Small Professor of Psychiatry, Psychiatry
  • 35346 Citations
  • 91 h-Index
1968 …2019
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Publications 1968 2019

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Article
2009
10 Citations (Scopus)

A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA)

Kramer, J. R., Chan, G., Kuperman, S., Bucholz, K. K., Edenberg, H., Schuckit, M. A., Polgreen, L. A., Kapp, E. S., Hesselbrock, V. M., Nurnberger, J. & Bierut, L. J., 2009, In : Journal of Studies on Alcohol and Drugs. 70, 4, p. 623-627 5 p.

Research output: Contribution to journalArticle

telephone interview
Telephone
alcoholism
Alcoholism
Interviews
413 Citations (Scopus)

A genome-wide linkage and association scan reveals novel loci for autism

Weiss, L. A., Arking, D. E., Daly, M. J., Chakravarti, A., Brune, C. W., West, K., O'Connor, A., Hilton, G., Tomlinson, R. L., West, A. B., Cook, E. H., Green, T., Chang, S. C., Gabriel, S., Gates, C., Hanson, E. M., Kirby, A., Korn, J., Kuruvilla, F., McCarroll, S. & 169 others, Morrow, E. M., Neale, B., Purcell, S., Sasanfar, R., Sougnez, C., Stevens, C., Altshuler, D., Gusella, J., Santangelo, S. L., Sklar, P., Tanzi, R., Anney, R., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Betancur, C., Bölte, S., Bolton, P. F., Brian, J., Bryson, S. E., Buxbaum, J. D., Cabrito, I., Cai, G., Cantor, R. M., Coon, H., Conroy, J., Correia, C., Corsello, C., Crawford, E. L., Cuccaro, M. L., Dawson, G., De Jonge, M., Devlin, B., Duketis, E., Ennis, S., Estes, A., Farrar, P., Fombonne, E., Freitag, C. M., Gallagher, L., Geschwind, D. H., Gilbert, J., Gill, M., Gillberg, C., Goldberg, J., Green, A., Green, J., Guter, S. J., Haines, J. L., Hallmayer, J. F., Hus, V., Klauck, S. M., Korvatska, O., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventha, B. L., Liu, X. Q., Lord, C., Lotspeich, L. J., Maestrini, E., Magalhaes, T., Mahoney, W., Mantoulan, C., McConachie, H., McDougle, C. J., McMahon, W. M., Marshall, C. R., Miller, J., Minshew, N. J., Monaco, A. P., Munson, J., Nurnberger, J., Oliveira, G., Pagnamenta, A., Papanikolaou, K., Parr, J. R., Paterson, A. D., Pericak-Vance, M. A., Pickles, A., Pinto, D., Piven, J., Posey, D. J., Poustka, A., Poustka, F., Regan, R., Reichert, J., Renshaw, K., Roberts, W., Roge, B., Rutter, M. L., Salt, J., Schellenberg, G. D., Scherer, S. W., Sheffield, V., Sutcliffe, J. S., Szatmari, P., Tansey, K., Thompson, A. P., Tsiantis, J., Van Engeland, H., Vicente, A. M., Vieland, V. J., Volkmar, F., Wallace, S., Wassink, T. H., Wijsman, E. M., Wing, K., Wittemeyer, K., Yaspan, B. L., Zwaigenbaum, L., Yoo, S. Y., Hill, R. S., Mukaddes, N. M., Balkhy, S., Gascon, G., Al-Saad, S., Hashmi, A., Ware, J., Joseph, R. M., LeClair, E., Partlow, J. N., Barry, B., Walsh, C. A., Pauls, D., Moilanen, I., Ebeling, H., Mattila, M. L., Kuusikko, S., Jussila, K., Ignatius, J., Tolouei, A., Ghadami, M., Rostami, M., Hosseinipour, A., Valujerdi, M., Andresen, K., Winkloski, B., Haddad, S., Kunkel, L., Kohane, Z., Tran, T., Won Kong, S., O'Neil, S. B., Hundley, R., Holm, I., Peters, H., Baroni, E., Cangialose, A., Jackson, L., Albers, L., Becker, R., Bridgemohan, C., Friedman, S., Munir, K., Nazir, R., Palfrey, J., Schonwald, A., Simmons, E., Rappaport, L. A., Gauthier, J., Mottron, L., Joober, R., Rouleau, G., Rehnstrom, K., Von Wendt, L. & Peltonen, L., Oct 8 2009, In : Nature. 461, 7265, p. 802-808 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Autistic Disorder
Chromosome Mapping
Single Nucleotide Polymorphism
Chromosomes
47 Citations (Scopus)

Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence

Chen, A. C. H., Tang, Y., Rangaswamy, M., Wang, J. C., Almasy, L., Foroud, T., Edenberg, H., Hesselbrock, V., Nurnberger, J., Kuperman, S., O'Connor, S., Schuckit, M. A., Bauer, L. O., Tischfield, J., Rice, J. P., Bierut, L., Goate, A. & Porjesz, B., Apr 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 3, p. 359-368 10 p.

Research output: Contribution to journalArticle

Glutamate Receptors
Alcoholism
Single Nucleotide Polymorphism
Genes
Delta Rhythm
872 Citations (Scopus)

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

Glessner, J. T., Wang, K., Cai, G., Korvatska, O., Kim, C. E., Wood, S., Zhang, H., Estes, A., Brune, C. W., Bradfield, J. P., Imielinski, M., Frackelton, E. C., Reichert, J., Crawford, E. L., Munson, J., Sleiman, P. M. A., Chiavacci, R., Annaiah, K., Thomas, K., Hou, C. & 39 others, Glaberson, W., Flory, J., Otieno, F., Garris, M., Soorya, L., Klei, L., Piven, J., Meyer, K. J., Anagnostou, E., Sakurai, T., Game, R. M., Rudd, D. S., Zurawiecki, D., McDougle, C. J., Davis, L. K., Miller, J., Posey, D. J., Michaels, S., Kolevzon, A., Silverman, J. M., Bernier, R., Levy, S. E., Schultz, R. T., Dawson, G., Owley, T., McMahon, W. M., Wassink, T. H., Sweeney, J. A., Nurnberger, J., Coon, H., Sutcliffe, J. S., Minshew, N. J., Grant, S. F. A., Bucan, M., Cook, E. H., Buxbaum, J. D., Devlin, B., Schellenberg, G. D. & Hakonarson, H., May 28 2009, In : Nature. 459, 7246, p. 569-572 4 p.

Research output: Contribution to journalArticle

Autistic Disorder
Ubiquitin
Genome
Genes
Neuronal Cell Adhesion Molecules
665 Citations (Scopus)

Common genetic variants on 5p14.1 associate with autism spectrum disorders

Wang, K., Zhang, H., Ma, D., Bucan, M., Glessner, J. T., Abrahams, B. S., Salyakina, D., Imielinski, M., Bradfield, J. P., Sleiman, P. M. A., Kim, C. E., Hou, C., Frackelton, E., Chiavacci, R., Takahashi, N., Sakurai, T., Rappaport, E., Lajonchere, C. M., Munson, J., Estes, A. & 36 others, Korvatska, O., Piven, J., Sonnenblick, L. I., Alvarez Retuerto, A. I., Herman, E. I., Dong, H., Hutman, T., Sigman, M., Ozonoff, S., Klin, A., Owley, T., Sweeney, J. A., Brune, C. W., Cantor, R. M., Bernier, R., Gilbert, J. R., Cuccaro, M. L., McMahon, W. M., Miller, J., State, M. W., Wassink, T. H., Coon, H., Levy, S. E., Schultz, R. T., Nurnberger, J., Haines, J. L., Sutcliffe, J. S., Cook, E. H., Minshew, N. J., Buxbaum, J. D., Dawson, G., Grant, S. F. A., Geschwind, D. H., Pericak-Vance, M. A., Schellenberg, G. D. & Hakonarson, H., May 28 2009, In : Nature. 459, 7246, p. 528-533 6 p.

Research output: Contribution to journalArticle

Cadherins
Single Nucleotide Polymorphism
Neuronal Cell Adhesion Molecules
Genome-Wide Association Study
Interpersonal Relations
133 Citations (Scopus)

Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

Le-Niculescu, H., Patel, S. D., Bhat, M., Kuczenski, R., Faraone, S. V., Tsuang, M. T., McMahon, F. J., Schork, N. J., Nurnberger, J. & Niculescu, A., Mar 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 2, p. 155-181 27 p.

Research output: Contribution to journalArticle

Genetic Association Studies
Genomics
Bipolar Disorder
Genome-Wide Association Study
Genome
7 Citations (Scopus)

Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter DOlvmorDhism

Maloney, B., Ray, B., Hayden, E. R., Nurnberger, J. & Lahiri, D., Apr 2009, In : Psychiatric Genetics. 19, 2, p. 72-82 11 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Genotype
DNA
Cheek
Polymerase Chain Reaction
46 Citations (Scopus)

Dissecting the phenotype in genome-wide association studies of psychiatric illness

Craddock, N., Kendler, K., Neale, M., Nurnberger, J., Purcell, S., Rietschel, M., Perlis, R., Santangelo, S. L., Schulze, T., Smoller, J. W. & Thapar, A., Aug 2009, In : British Journal of Psychiatry. 195, 2, p. 97-99 3 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Psychiatry
Phenotype
1 Citation (Scopus)

Erratum: Identifying blood biomarkers for mood disorders using convergent functional genomics (Molecular Psychiatry (2009) 14 (156-174) DOI: 10.1038/mp.2008.11)

Le-Niculescu, H., Kurian, S. M., Yehyawi, N., Dike, C., Patel, S. D., Edenberg, H., Tsuang, M. T., Salomon, D. R., Nurnberger, J. & Niculescu, A., Dec 2009, In : Molecular Psychiatry. 14, 12, p. 1143 1 p.

Research output: Contribution to journalArticle

Genomics
Mood Disorders
Psychiatry
Biomarkers
39 Citations (Scopus)

Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence

Agrawal, A., Wetherill, L., Dick, D. M., Xuei, X., Hinrichs, A., Hesselbrock, V., Kramer, J., Nurnberger, J., Schuckit, M., Bierut, L. J., Edenberg, H. & Foroud, T., Jul 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 5, p. 736-740 5 p.

Research output: Contribution to journalArticle

Marijuana Abuse
Cannabinoid Receptors
Single Nucleotide Polymorphism
Genes
Chromosomes, Human, Pair 15
31 Citations (Scopus)

Eyeblink conditioning anomalies in bipolar disorder suggest cerebellar dysfunction

Bolbecker, A. R., Mehta, C., Johannesen, J. K., Edwards, C. R., O'Donnell, B., Shekhar, A., Nurnberger, J., Steinmetz, J. E. & Hetrick, W. P., 2009, In : Bipolar Disorders. 11, 1, p. 19-32 14 p.

Research output: Contribution to journalArticle

Cerebellar Diseases
Bipolar Disorder
Cerebellum
Research
Cues
121 Citations (Scopus)

Family-based association of FKBP5 in bipolar disorder

Willour, V. L., Chen, H., Toolan, J., Belmonte, P., Cutler, D. J., Goes, F. S., Zandi, P. P., Lee, R. S., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., DePaulo, J. R., Gershon, E. S., McMahon, F. J., Potash, J. B., McMahon, F., Steele, J., Pearl, J., Kassem, L., Lopez, V. & 64 others, Potash, J., MacKinnon, D., Miller, E., Toolan, J., Zandi, P., Schulze, T., Nwulia, E., Simpson, S., Nurnberger, J., Miller, M., Bowman, E., Reich, T., Goate, A., Rice, J., DePaulo, J. R., Stine, C., Gershon, E., Kazuba, D., Maxwell, E., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Bierut, L., McInnis, M., MacKinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Badner, J., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F. J., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Mar 2009, In : Molecular Psychiatry. 14, 3, p. 261-268 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Single Nucleotide Polymorphism
Genetic Models
Glucocorticoid Receptors
Antidepressive Agents
33 Citations (Scopus)

Family-based association of YWHAH in psychotic bipolar disorder

Grover, D., Verma, R., Goes, F. S., Belmonte Mahon, P. L., Gershon, E. S., McMahon, F. J., Potash, J. B., McMahon, F. J., Steele, J., Pearl, J., Kassem, L., Lopez, V., Schulze, T., Potash, J., MacKinnon, D., Miller, E., Toolan, J., Zandi, P., Simpson, S., Nurnberger, J. & 64 others, Miller, M., Bowman, E., Reich, T., Goate, A., Rice, J., DePaulo, J. R., Simpson, S., Stine, C., Gershon, E., Kazuba, D., Maxwell, E., Nurnberger, J., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Rice, J., Reich, T., Goate, A., Bierut, L., McInnis, M., DePaulo, J. R., MacKinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Gershon, E., Badner, J., McMahon, F., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F., Kassem, L., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Oct 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 7, p. 977-983 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Psychotic Disorders
Schizophrenia
Single Nucleotide Polymorphism
Chromosome Disorders
155 Citations (Scopus)

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

Wang, J. C., Grucza, R., Cruchaga, C., Hinrichs, A. L., Bertelsen, S., Budde, J. P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B. & 3 others, Edenberg, H., Bierut, L. J. & Goate, A. M., May 2009, In : Molecular Psychiatry. 14, 5, p. 501-510 10 p.

Research output: Contribution to journalArticle

Alcoholism
Messenger RNA
Genes
Tobacco Use Disorder
Smoking
275 Citations (Scopus)

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

Bucan, M., Abrahams, B. S., Wang, K., Glessner, J. T., Herman, E. I., Sonnenblick, L. I., Alvarez Retuerto, A. I., Imielinski, M., Hadley, D., Bradfield, J. P., Kim, C., Gidaya, N. B., Lindquist, I., Hutman, T., Sigman, M., Kustanovich, V., Lajonchere, C. M., Singleton, A., Kim, J., Wassink, T. H. & 16 others, McMahon, W. M., Owley, T., Sweeney, J. A., Coon, H., Nurnberger, J., Li, M., Cantor, R. M., Minshew, N. J., Sutcliffe, J. S., Cook, E. H., Dawson, G., Buxbaum, J. D., Grant, S. F. A., Schellenberg, G. D., Geschwind, D. H. & Hakonarson, H., Jun 2009, In : PLoS Genetics. 5, 6, e1000536.

Research output: Contribution to journalArticle

Autistic Disorder
genome
Genome
Gene Duplication
gene
298 Citations (Scopus)

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Cichon, S., Craddock, N., Daly, M., Faraone, S. V., Gejman, P. V., Kelsoe, J., Lehner, T., Levinson, D. F., Moran, A., Sklar, P., Sullivan, P. F., Anney, R., Gill, M., Corvin, A., Buitelaar, J., Franke, B., Elia, J., Hakonarson, H., Kent, L., McGough, J. & 103 others, Smalley, S., Ophoff, R., Mick, E., Santangelo, S., Ferreira, M., Purcell, S., Ruderfer, D., Smoller, J., Perlis, R., Neale, B., Stone, J., Nisenbaum, L., Thapar, A., Moskvina, V., Holmans, P., O'Donovan, M., Owen, M., Todd, R., Todorov, A., Rice, J., Devlin, B., Arking, D., Chakravarti, A., Potash, J. B., Pulver, A., Buxbaum, J. D., Cook, E., Peltonen, L., Suvisaari, J., Piven, J., Lin, D., Sullivan, P., Rouleau, G., Awadalla, P., Schellenberg, G., Scherer, S., Sutcliffe, J., Szatmari, P., Vieland, V., Andreassen, O. A., Frigessi, A., Blackwood, D., Muir, W., Boehnke, M., Burmeister, M., Flickinger, M., Guan, W., Li, J., Scott, L., Breuer, R., Rietschel, M., Schulze, T., Greenwood, T., Schork, N., Gurling, H., Muglia, P., Upmanyu, R., Tozzi, F., Noethen, M., Wienker, T., Steffens, M., Nurnberger, J., Kendler, K., Riley, B., van den Oord, E., Boomsma, D., de Geus, E., Hoogendijk, W., Penninx, B., Willemsen, A. H. M., Posthuma, D., Coryell, W., Hamilton, S., Kloiber, S., Lucae, S., Ripke, S., Lawson, W. B., Lewis, C., McGuffin, P., Martin, N., Wray, N., McGrath, P., Weissman, M. M., Offord, J., Scheftner, W. A., Slager, S., Fanous, A., Hultman, C., Kivikko, S., Laurent, C., Lencz, T., Malhotra, A., Mowry, B., Holliday, E., Sanders, A., Schwab, S., Wildenaver, D., St. Clair, D., Dudbridge, F., Pickering, E., Posthuma, D., Sebat, J. & Tzeng, J. Y., May 2009, In : American Journal of Psychiatry. 166, 5, p. 540-556 17 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Psychiatry
History
Meta-Analysis
Linkage Disequilibrium
234 Citations (Scopus)

Genome-wide association study of bipolar disorder in European American and African American individuals

Smith, E. N., Bloss, C. S., Badner, J. A., Barrett, T., Belmonte, P. L., Berrettini, W., Byerley, W., Coryell, W., Craig, D., Edenberg, H., Eskin, E., Foroud, T., Gershon, E., Greenwood, T. A., Hipolito, M., Koller, D. L., Lawson, W. B., Liu, C., Lohoff, F., McInnis, M. G. & 17 others, McMahon, F. J., Mirel, D. B., Murray, S. S., Nievergelt, C., Nurnberger, J., Nwulia, E. A., Paschall, J., Potash, J. B., Rice, J., Schulze, T. G., Scheftner, W., Panganiban, C., Zaitlen, N., Zandi, P. P., Zöllner, S., Schork, N. J. & Kelsoe, J. R., Aug 2009, In : Molecular Psychiatry. 14, 8, p. 755-763 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
African Americans
Single Nucleotide Polymorphism
Intergenic DNA
56 Citations (Scopus)

Genome-wide linkage and follow-up association study of postpartum mood symptoms

Mahon, P. B., Payne, J. L., MacKinnon, D. F., Mondimore, F. M., Goes, F. S., Schweizer, B., Jancic, D., Coryell, W. H., Holmans, P. A., Shi, J., Knowles, J. A., Scheftner, W. A., Weissman, M. M., Levinson, D. F., DePaulo, J. R., Zandi, P. P., Potash, J. B., Kelsoe, J. R., Greenwood, T. A., Nievergelt, C. & 22 others, Schork, N., Smith, E. N., Bloss, C., Nurnberger, J., Edenberg, H. J., Foroud, T., Nurnberger, J., Liu, C., Badner, J. A., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F., Schulze, T. G., Berrettini, W., McInnis, M. G., Zöllner, S., Craig, D. & Edenberg, H., Nov 1 2009, In : American Journal of Psychiatry. 166, 11, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

Postpartum Period
Genome
Chromosomes
Mood Disorders
Single Nucleotide Polymorphism
138 Citations (Scopus)

Identifying blood biomarkers for mood disorders using convergent functional genomics

Le-Niculescu, H., Kurian, S. M., Yehyawi, N., Dike, C., Patel, S. D., Edenberg, H., Tsuang, M. T., Salomon, D. R., Nurnberger, J. & Niculescu, A., Feb 2009, In : Molecular Psychiatry. 14, 2, p. 156-174 19 p.

Research output: Contribution to journalArticle

Genomics
Mood Disorders
Biomarkers
Gene Expression
Brain Diseases
1 Citation (Scopus)

New hope for pharmacogenetic testing

Nurnberger, J., Jun 2009, In : American Journal of Psychiatry. 166, 6, p. 635-638 4 p.

Research output: Contribution to journalArticle

Psychomotor Disorders
Lithium Carbonate
Diabetes Insipidus
AMPA Receptors
Pharmacogenetics
9 Citations (Scopus)

Premenstrual mood symptoms: Study of familiality and personality correlates in mood disorder pedigrees

NIMH Genetics Initiative Bipolar Disorder Consortium, Feb 1 2009, In : Archives of Women's Mental Health. 12, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Pedigree
Mood Disorders
Personality
Bipolar Disorder
Major Depressive Disorder
113 Citations (Scopus)

Singleton deletions throughout the genome increase risk of bipolar disorder

Zhang, D., Cheng, L., Qian, Y., Alliey-Rodriguez, N., Kelsoe, J. R., Greenwood, T., Nievergelt, C., Barrett, T. B., McKinney, R., Schork, N., Smith, E. N., Bloss, C., Nurnberger, J., Edenberg, H., Foroud, T., Sheftner, W., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W. & 16 others, Rice, J., Byerley, W., McMahon, F., Schulze, T. G., Berrettini, W., Potash, J. B., Belmonte, P. L., Zandi, P. P., McInnis, M. G., Zöllner, S., Craig, D., Szelinger, S., Koller, D., Christian, S. L., Liu, C. & Gershon, E. S., Apr 2009, In : Molecular Psychiatry. 14, 4, p. 376-380 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Genome
Single Nucleotide Polymorphism
Genomic Structural Variation
Age of Onset
2008
39 Citations (Scopus)

A Multimethod Investigation of the Behavioral Activation System in Bipolar Disorder

Hayden, E. P., Bodkins, M., Brenner, C., Shekhar, A., Nurnberger, J., O'Donnell, B. & Hetrick, W. P., Feb 2008, In : Journal of Abnormal Psychology. 117, 1, p. 164-170 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Reward
Self Report
4 Citations (Scopus)

A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs

Ghosh, S., Bierut, L. J., Porjesz, B., Edenberg, H., Dick, D., Goate, A., Hesselbrock, V., Nurnberger, J., Foroud, T., Kramer, J., Rice, J. & Begleiter, H., Oct 5 2008, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 147, 7, p. 1301-1305 5 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 4
Alcoholism
Chromosomes, Human, Pair 15
Chromosomes, Human, Pair 1
Multigene Family
55 Citations (Scopus)

A regulatory variation in OPRK1, the gene encoding the κ-opioid receptor, is associated with alcohol dependence

Edenberg, H., Wang, J., Tian, H., Pochareddy, S., Xuei, X., Wetherill, L., Goate, A., Hinrichs, T., Kuperman, S., Nurnberger, J., Schuckit, M., Tischfield, J. A. & Foroud, T., Jun 15 2008, In : Human Molecular Genetics. 17, 12, p. 1783-1789 7 p.

Research output: Contribution to journalArticle

Opioid Receptors
Alcoholism
Genes
Transcription Initiation Site
DNA Sequence Analysis
100 Citations (Scopus)

A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence

Grucza, R. A., Wang, J. C., Stitzel, J. A., Hinrichs, A. L., Saccone, S. F., Saccone, N. L., Bucholz, K. K., Cloninger, C. R., Neuman, R. J., Budde, J. P., Fox, L., Bertelsen, S., Kramer, J., Hesselbrock, V., Tischfield, J., Nurnberger, J., Almasy, L., Porjesz, B., Kuperman, S., Schuckit, M. A. & 4 others, Edenberg, H., Rice, J. P., Goate, A. M. & Bierut, L. J., Dec 1 2008, In : Biological Psychiatry. 64, 11, p. 922-929 8 p.

Research output: Contribution to journalArticle

Cocaine-Related Disorders
Tobacco Use Disorder
Alleles
Alcoholism
Genetic Models
5 Citations (Scopus)

A simulated genetic structure for bipolar illness

Nurnberger, J., Sep 5 2008, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 147, 6, p. 952-956 5 p.

Research output: Contribution to journalArticle

Genetic Structures
Alleles
Genes
Neurobiology
Genome-Wide Association Study
34 Citations (Scopus)

Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence

Xuei, X., Flury-Wetherill, L., Almasy, L., Bierut, L., Tischfield, J., Schuckit, M., Nurnberger, J., Foroud, T. & Edenberg, H., Mar 2008, In : Addiction Biology. 13, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

Street Drugs
Substance-Related Disorders
Single Nucleotide Polymorphism
Alcohols
Ligands
69 Citations (Scopus)

Association of NFKB1, which encodes a subunit of the transcription factor NF-κB, with alcohol dependence

Edenberg, H., Xuei, X., Wetherill, L. F., Bierut, L., Bucholz, K., Dick, D. M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M. A., Tischfield, J. A., Almasy, L. A., Nurnberger, J. & Foroud, T., Apr 1 2008, In : Human Molecular Genetics. 17, 7, p. 963-970 8 p.

Research output: Contribution to journalArticle

Alcoholism
Transcription Factors
Single Nucleotide Polymorphism
Genes
Alcoholics
50 Citations (Scopus)

Association study of Wnt signaling pathway genes in bipolar disorder

Zandi, P. P., Belmonte, P. L., Willour, V. L., Goes, F. S., Badner, J. A., Simpson, S. G., Gershon, E. S., McMahon, F. J., DePaulo, J. R., Potash, J. B., Steele, J., Pearl, J., Kassem, L., Lopez, V., MacKinnon, D., Miller, E., Toolan, J., Schulze, T., Byerley, W., Coryell, W. & 3 others, Kelsoe, J., Rice, J. & Nurnberger, J., Jul 2008, In : Archives of General Psychiatry. 65, 7, p. 785-793 9 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Bipolar Disorder
Single Nucleotide Polymorphism
Genes
Odds Ratio
36 Citations (Scopus)

A Systematic Single Nucleotide Polymorphism Screen to Fine-Map Alcohol Dependence Genes on Chromosome 7 Identifies Association With a Novel Susceptibility Gene ACN9

Dick, D. M., Aliev, F., Wang, J. C., Saccone, S., Hinrichs, A., Bertelsen, S., Budde, J., Saccone, N., Foroud, T., Nurnberger, J., Xuei, X., Conneally, P. M., Schuckit, M., Almasy, L., Crowe, R., Kuperman, S., Kramer, J., Tischfield, J. A., Hesselbrock, V., Edenberg, H. & 4 others, Porjesz, B., Rice, J. P., Bierut, L. & Goate, A., Jun 1 2008, In : Biological Psychiatry. 63, 11, p. 1047-1053 7 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 7
Alcoholism
Single Nucleotide Polymorphism
Genes
HapMap Project
49 Citations (Scopus)

Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism

Hayden, E. P., Dougherty, L. R., Maloney, B., Olino, T. M., Sheikh, H., Durbin, C. E., Nurnberger, J., Lahiri, D. & Klein, D. N., Apr 2008, In : Journal of Affective Disorders. 107, 1-3, p. 227-230 4 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Genetic Promoter Regions
Genotype
Depression
Automatic Data Processing
42 Citations (Scopus)

Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder

Liu, L., Foroud, T., Xuei, X., Berrettini, W., Byerley, W., Coryell, W., El-Mallakh, R., Gershon, E. S., Kelsoe, J. R., Lawson, W. B., MacKinnon, D. F., McInnis, M., McMahon, F. J., Murphy, D. L., Rice, J., Scheftner, W., Zandi, P. R., Lohoff, F. W., Niculescu, A., Meyer, E. T. & 2 others, Edenberg, H. & Nurnberger, J., Dec 2008, In : Psychiatric Genetics. 18, 6, p. 267-274 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Bipolar Disorder
Single Nucleotide Polymorphism
Genes
Mood Disorders
28 Citations (Scopus)

Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees

Payne, J. L., Mackinnon, D. F., Mondimore, F. M., Mcinnis, M. G., Schweizer, B., Zamoiski, R. B., Mcmahon, F. J., Nurnberger, J., Rice, J. P., Scheftner, W., Coryell, W., Berrettini, W. H., Kelsoe, J. R., Byerley, W., Gershon, E. S., Depaulo, J. R. & Potash, J. B., Feb 2008, In : Bipolar Disorders. 10, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

Pedigree
Bipolar Disorder
Postpartum Period
Interviews
Depression
11 Citations (Scopus)

Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20

Ross, J., Berrettini, W., Coryell, W., Gershon, E. S., Badner, J. A., Kelsoe, J. R., McInnis, M. G., McMahon, F. J., Murphy, D. L., Nurnberger, J., Foroud, T., Rice, J. P., Scheftner, W. B., Zandi, P., Edenberg, H. & Byerley, W., Aug 2008, In : Psychiatric Genetics. 18, 4, p. 191-198 8 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 20
Chromosomes, Human, Pair 16
Pedigree
Genome
Bipolar Disorder
51 Citations (Scopus)

Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample

Agrawal, A., Hinrichs, A. L., Dunn, G., Bertelsen, S., Dick, D. M., Saccone, S. F., Saccone, N. L., Grucza, R. A., Wang, J. C., Cloninger, C. R., Edenberg, H., Foroud, T., Hesselbrock, V., Kramer, J., Bucholz, K. K., Kuperman, S., Nurnberger, J., Porjesz, B., Schuckit, M. A., Goate, A. M. & 1 others, Bierut, L. J., Jan 11 2008, In : Drug and Alcohol Dependence. 93, 1-2, p. 12-20 9 p.

Research output: Contribution to journalArticle

alcoholism
Alcoholism
Substance-Related Disorders
drug dependence
alcohol
22 Citations (Scopus)

Multiple-domain predictors of problematic alcohol use in young adulthood

Kramer, J. R., Chan, G., Dick, D. M., Kuperman, S., Bucholz, K. K., Edenberg, H., Polgreen, L. A., Hesselbrock, V. M., Schuckit, M. A., Nurnberger, J., Kapp, E. S., Porjesz, B. & Bierut, L. J., Sep 2008, In : Journal of Studies on Alcohol and Drugs. 69, 5, p. 649-659 11 p.

Research output: Contribution to journalArticle

adulthood
alcohol
Alcohols
Young Adult
young adult
58 Citations (Scopus)

Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence

Wetherill, L., Schuckit, M. A., Hesselbrock, V., Xuei, X., Liang, T., Dick, D. M., Kramer, J., Nurnberger, J., Tischfield, J. A., Porjesz, B., Edenberg, H. & Foroud, T., Dec 2008, In : Alcoholism: Clinical and Experimental Research. 32, 12, p. 2031-2040 10 p.

Research output: Contribution to journalArticle

Neuropeptide Y Receptors
Cocaine-Related Disorders
Cocaine
Alcoholism
Genes
82 Citations (Scopus)

Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism

Le-Niculescu, H., McFarland, M. J., Ogden, C. A., Balaraman, Y., Patel, S., Tan, J., Rodd, Z., Paulus, M., Geyer, M. A., Edenberg, H., Glatt, S. J., Faraone, S. V., Nurnberger, J., Kuczenski, R., Tsuang, M. T. & Niculescu, A., Mar 5 2008, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 147, 2, p. 134-166 33 p.

Research output: Contribution to journalArticle

Genetic Models
Bipolar Disorder
Alcoholism
Animal Models
Biomarkers
36 Citations (Scopus)

The prognostic implications of DSM-IV abuse criteria in drinking adolescents

Schuckit, M. A., Danko, G. P., Smith, T. L., Bierut, L. J., Bucholz, K. K., Edenberg, H., Hesselbrock, V., Kramer, J., Nurnberger, J., Trim, R., Allen, R., Kreikebaum, S. & Hinga, B., Sep 1 2008, In : Drug and Alcohol Dependence. 97, 1-2, p. 94-104 11 p.

Research output: Contribution to journalArticle

Diagnostic and Statistical Manual of Mental Disorders
Alcoholism
abuse
Alcohols
adolescent
30 Citations (Scopus)

The tachykinin receptor 3 is associated with alcohol and cocaine dependence

Foroud, T., Wetherill, L. F., Kramer, J., Tischfield, J. A., Nurnberger, J., Schuckit, M. A., Xuei, X. & Edenberg, H., Jun 2008, In : Alcoholism: Clinical and Experimental Research. 32, 6, p. 1023-1030 8 p.

Research output: Contribution to journalArticle

Tachykinin Receptors
Cocaine-Related Disorders
Cocaine
Alcoholism
Alcohols
55 Citations (Scopus)

Under the influence of genetics: How transdisciplinarity leads us to rethink social pathways to illness

Pescosolido, B. A., Perry, B. L., Long, J. S., Martin, J. K., Nurnberger, J. & Hesseibrock, V., 2008, In : American Journal of Sociology. 114, SUPPL. 1

Research output: Contribution to journalArticle

illness
alcohol
transdisciplinary
social process
deprivation
410 Citations (Scopus)

Variants in nicotinic receptors and risk for nicotine dependence

Bierut, L. J., Stitzel, J. A., Wang, J. C., Hinrichs, A. L., Grucza, R. A., Xuei, X., Saccone, N. L., Saccone, S. F., Bertelsen, S., Fox, L., Horton, W. J., Breslau, N., Budde, J., Cloninger, C. R., Dick, D. M., Foroud, T., Hatsukami, D., Hesselbrock, V., Johnson, E. O., Kramer, J. & 13 others, Kuperman, S., Madden, P. A. F., Mayo, K., Nurnberger, J., Pomerleau, O., Porjesz, B., Reyes, O., Schuckit, M., Swan, G., Tischfield, J. A., Edenberg, H., Rice, J. P. & Goate, A. M., Sep 2008, In : American Journal of Psychiatry. 165, 9, p. 1163-1171 9 p.

Research output: Contribution to journalArticle

Tobacco Use Disorder
Nicotinic Receptors
Smoking
Population
Amino Acids
2007
39 Citations (Scopus)

A comparison of factors associated with substance-induced versus independent depressions

Schuckit, M. A., Smith, T. L., Danko, G. P., Pierson, J., Trim, R., Nurnberger, J., Kramer, J., Kuperman, S., Bierut, L. J. & Hesselbrock, V., Nov 2007, In : Journal of Studies on Alcohol and Drugs. 68, 6, p. 805-812 8 p.

Research output: Contribution to journalArticle

Alcoholics
Alcoholism
alcoholism
Depression
Alcohols
66 Citations (Scopus)

Alcohol dependence with comorbid drug dependence: Genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk

Dick, D. M., Agrawal, A., Wang, J. C., Hinrichs, A., Bertelsen, S., Bucholz, K. K., Schuckit, M., Kramer, J., Nurnberger, J., Tischfield, J., Edenberg, H., Goate, A. & Bierut, L. J., Jul 2007, In : Addiction. 102, 7, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

Alcoholism
Substance-Related Disorders
Alcohols
Street Drugs
Muscarinic M2 Receptors
55 Citations (Scopus)

Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample

Dick, D. M., Plunkett, J., Hamlin, D., Nurnberger, J., Kuperman, S., Schuckit, M., Hesselbrock, V., Edenberg, H. & Bierut, L., Feb 2007, In : Psychiatric Genetics. 17, 1, p. 35-38 4 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Alcoholism
Depression
Genes
Unemployment
63 Citations (Scopus)

Association of alcohol craving with α-synuclein (SNCA)

Foroud, T., Wetherill, L. F., Liang, T., Dick, D. M., Hesselbrock, V., Kramer, J., Nurnberger, J., Schuckit, M., Carr, L., Porjesz, B., Xuei, X. & Edenberg, H., Apr 2007, In : Alcoholism: Clinical and Experimental Research. 31, 4, p. 537-545 9 p.

Research output: Contribution to journalArticle

Synucleins
Alcohols
Alcoholism
Single Nucleotide Polymorphism
Haplotypes
47 Citations (Scopus)

Association of CHRM2 with IQ: Converging evidence for a gene influencing intelligence

Dick, D. M., Aliev, F., Kramer, J., Wang, J. C., Hinrichs, A., Bertelsen, S., Kuperman, S., Schuckit, M., Nurnberger, J., Edenberg, H., Porjesz, B., Begleiter, H., Hesselbrock, V., Goate, A. & Bierut, L., Mar 2007, In : Behavior Genetics. 37, 2, p. 265-272 8 p.

Research output: Contribution to journalArticle

cholinergic agents
Muscarinic Receptors
Intelligence
Cholinergic Agents
receptors
54 Citations (Scopus)

Candidate genes, pathways and mechanisms for alcoholism: An expanded convergent functional genomics approach

Rodd, Z., Bertsch, B. A., Strother, W. N., Le-Niculescu, H., Balaraman, Y., Hayden, E., Jerome, R. E., Lumeng, L., Nurnberger, J., Edenberg, H., McBride, W. J. & Niculescu, A., Aug 2007, In : Pharmacogenomics Journal. 7, 4, p. 222-256 35 p.

Research output: Contribution to journalArticle

Genomics
Alcoholism
Alcohols
Genes
Angiotensin-Converting Enzyme Inhibitors
41 Citations (Scopus)

Convergent Functional Genomics of bipolar disorder: From animal model pharmacogenomics to human genetics and biomarkers

Le-Niculescu, H., McFarland, M. J., Mamidipalli, S., Ogden, C. A., Kuczenski, R., Kurian, S. M., Salomon, D. R., Tsuang, M. T., Nurnberger, J. & Niculescu, A., 2007, In : Neuroscience and Biobehavioral Reviews. 31, 6, p. 897-903 7 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Medical Genetics
Genomics
Bipolar Disorder
Animal Models