John Nurnberger

  • Joyce & Iver Small Professor of Psychiatry, Psychiatry
  • 38321 Citations
  • 94 h-Index
1968 …2020

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Publications

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2002

A comparison of alcohol-induced and independent depression in alcoholics with histories of suicide attempts

Preuss, U. W., Schuckit, M. A., Smith, T. L., Danko, G. P., Dasher, A. C., Hesselbrock, M. N., Hesselbrock, V. M. & Nurnberger, J. I., Jan 1 2002, In : Journal of Studies on Alcohol. 63, 4, p. 498-502 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

Apparent replication of suggestive linkage on chromosome 16 in the NIMH genetics initiative bipolar pedigrees

Dick, D. M., Foroud, T., Edenberg, H. J., Miller, M., Bowman, E., Leela Rau, N., Raymond Depaulo, J., McInnis, M., Gershon, E., McMahon, F., Rice, J. P., Bierut, L. J., Reich, T. & Nurnberger, J., May 8 2002, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 114, 4, p. 407-412 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Comorbid bipolar disorder and panic disorder in families with a high prevalence of bipolar disorder

MacKinnon, D. F., Zandi, P. P., Cooper, J., Potash, J. B., Simpson, S. G., Gershon, E., Nurnberger, J., Reich, T. & DePaulo, J. R., Jan 1 2002, In : American Journal of Psychiatry. 159, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

143 Scopus citations

Defining alcohol-related phenotypes in humans: The collaborative study on the genetics of alcoholism

Bierut, L. J., Saccone, N. L., Rice, J. P., Goate, A., Foroud, T., Edenberg, H., Almasy, L., Conneally, P. M., Crowe, R., Hesselbrock, V., Li, T. K., Nurnberger, J., Porjesz, B., Schuckit, M. A., Tischfield, J., Begleiter, H. & Reich, T., Dec 1 2002, In : Alcohol Research and Health. 26, 3, p. 208-213 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Developmental expression of the β-amyloid precursor protein and heat-shock protein 70 in the cerebral hemisphere region of the rat brain

Lahiri, D. K., Nall, C., Chen, D., Zaphiriou, M., Morgan, C. & Nurnberger, J. I., Jan 1 2002, In : Annals of the New York Academy of Sciences. 965, p. 324-333 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Is there a genetic relationship between alcoholism and depression?

Nurnberger, J. I., Foroud, T., Flury, L., Meyer, E. T. & Wiegand, R., Dec 1 2002, In : Alcohol Research and Health. 26, 3, p. 233-240 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Linkage for platelet monoamine oxidase (MAO) activity: Results from a replication sample

Saccone, N. L., Rice, J. P., Rochberg, N., Williams, J. T., Goate, A., Reich, T., Edenberg, H. J., Foroud, T., Nurnberger, J. I., Bierut, L. J., Crowe, R. & Li, T. K., Jan 1 2002, In : Alcoholism: Clinical and Experimental Research. 26, 5, p. 603-609 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype

Dick, D. M., Nurnberger, J., Edenberg, H. J., Goate, A., Crowe, R., Rice, J., Bucholz, K. K., Kramer, J., Schuckit, M. A., Smith, T. L., Porjesz, B., Begleiter, H., Hesselbrock, V. & Foroud, T., Oct 2002, In : Alcoholism: Clinical and Experimental Research. 26, 10, p. 1453-1460 8 p.

Research output: Contribution to journalArticle

72 Scopus citations
2001

A bootstrapped commingling analysis of platelet monoamine oxidase activity levels corrected for cigarette smoking

Daw, E. W., Rice, J. P., Anthenelli, R. M., Schuckit, M. A., Tipp, J., Saccone, N. L., Reich, T., Nurnberger, J. I. & Li, T. K., Dec 1 2001, In : Psychiatric genetics. 11, 4, p. 177-185 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alcoholism and mania: Is there a genetic relationship?

Nurnberger, J. I., Meyer, E. T., Flury, L., Hu, K. & Foroud, T., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

Alcohol use and dependence in parents and offspring

Moe, P. R., Nurnberger, J. I., Meyer, E. T. & Wildblood, R., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

A multiple threshold liability model suggests linkage of alcohol dependence to three loci in the COGA data set

Corbett, J., Rice, J. P., Goate, A., Bierut, L. J., Edenberg, H. J., Nurnberger, J. & Reich, T., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

A quantitative estimate of genetic vulnerability for a multifactorial condition

Nurnberger, J. I., Foroud, T., Hu, K., Castellucio, P., Edenberg, H. J. & Meyer, E. T., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder

Nurnberger, J. I., Foroud, T., Flury, L., Su, J., Meyer, E. T., Hu, K., Crowe, R., Edenberg, H., Goate, A., Bierut, L., Reich, T., Schuckit, M. & Reich, W., May 2001, In : American Journal of Psychiatry. 158, 5, p. 718-724 7 p.

Research output: Contribution to journalArticle

165 Scopus citations

Genome scan on fifty-six multiplex bipolar pedigrees collected by the NIMH Genetics Initiative (Bipolar Disorder)

Willour, V. L., Zandi, P. P., Gershon, E. S., Nurnberger, J. I., Reich, T., Depaulo, J. R. & McInnis, M. G., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Park city, utah molecular psychiatry meeting, february 2001

Nurnberger, J., Jun 13 2001, In : Psychiatric genetics. 11, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

Perceived Genetic Risks for Bipolar Disorder in a Patient Population: An Exploratory Study

Quaid, K. A., Aschen, S. R., Smiley, C. L. & Nurnberger, J. I., Dec 1 2001, In : Journal of Genetic Counseling. 10, 1, p. 41-51 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Replication of suggestive linkage on chromosomes 5 and 16 in the NIMH genetics initiative bipolar pedigrees

Dick, D. M., Nurnberger, J. I., Edenberg, H., McInnis, M. G., Reich, T., Gershon, E. S. & Foroud, T., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

Sequence analysis of an intronless gene within GNAL on 18q11 in individuals affected with bipolar disorder

Trofatter, J. A., Nurnberger, K. M., Berrettini, W. H. & Nurnberger, J. I., Oct 8 2001, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 7, 1 p.

Research output: Contribution to journalArticle

Traumatic brain injury and schizophrenia in members of schizophrenia and bipolar disorder pedigrees

Malaspina, D., Goetz, R. R., Friedman, J. H., Kaufmann, C. A., Faraone, S. V., Tsuang, M., Cloninger, C. R., Nurnberger, J. & Blehar, M. C., Mar 21 2001, In : American Journal of Psychiatry. 158, 3, p. 440-446 7 p.

Research output: Contribution to journalArticle

99 Scopus citations
2000

Alcoholism susceptibility loci: Confirmation studies in a replicate sample and further mapping

Foroud, T., Edenberg, H. J., Goate, A., Rice, J., Flury, L., Koller, D. L., Bierut, L. J., Conneally, P. M., Nurnberger, J. I., Bucholz, K. K., Li, T. K., Hesselbrock, V., Crowe, R., Schuckit, M., Porjesz, B., Begleiter, H. & Reich, T., Jul 2000, In : Alcoholism: Clinical and Experimental Research. 24, 7, p. 933-945 13 p.

Research output: Contribution to journalArticle

209 Scopus citations

Allele frequency heterogeneity in the collaborative study on the genetics of alcoholism (COGA)

Saccone, N. L., Rice, J. P., Goate, A., Conneally, P. M., Edenberg, H., Foroud, T., Nurnberger, J. & Reich, T., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, 1 p.

Research output: Contribution to journalArticle

Allelic distribution of CTG18.1 in Caucasian populations: Association studies in bipolar disorder, schizophrenia, and ataxia

McInnis, M. G., Swift-Scanlanl, T., Mahoney, A. T., Vincent, J., Verheyen, G., Hung Lan, T., Oruc, L., Riess, O., Van Broeckhoven, C., Chen, H., Kennedy, J. L., MacKinnon, D. F., Margolis, R. L., Simpson, S. G., McMahon, F. J., Gershon, E., Nürnberger, J., Reich, T., Depaulo, J. R. & Ross, C. A., Jan 1 2000, In : Molecular Psychiatry. 5, 4, p. 439-442 4 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women

Daeppen, J. B., Smith, T. L., Danko, G. P., Gordon, L., Landi, N. A., Nurnberger, J. I., Bucholz, K. K., Raimo, E., Schuckit, M. A., Li, T. K., Conneally, P. M., Edenberg, H., Crowe, R., Kuperman, S., Bloom, F., Hesselbrock, V., Begleiter, H., Porjesz, B., Reich, T., Cloninger, C. R. & 1 others, Rice, J., Jan 1 2000, In : Alcohol and Alcoholism. 35, 2, p. 171-175 5 p.

Research output: Contribution to journalArticle

Open Access
113 Scopus citations

Common and specific factors in the familial transmission of substance dependence

Bierut, L., Rice, J., Goate, A., Foroud, T., Edenberg, H., Crowe, R., Hesselbrock, V., Li, T. K., Nurnberger, J., Porjesz, B., Schuckit, M., Begleiter, H. & Reich, T., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking

Bierut, L. J., Rice, J. P., Edenberg, H. J., Goate, A., Foroud, T., Cloninger, C. R., Begleiter, H., Conneally, P. M., Crowe, R. R., Hesselbrock, V., Li, T. K., Nurnberger, J. I., Porjesz, B., Schuckit, M. A. & Reich, T., Feb 17 2000, In : American journal of medical genetics. 90, 4, p. 299-302 4 p.

Research output: Contribution to journalArticle

96 Scopus citations

Family studies of co-occurring bipolar disorder and substance abuse

Lawson, W. B., Meyer, E., Hu, K., DePaulo, R., Gershon, E., Reich, T., Nurnberger, J. & Roudebush, V. A. M. C., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, p. 505-506 2 p.

Research output: Contribution to journalArticle

Further analyses of the NIMH bipolar dataset: Follow up on suggestive linkage results on 1p and 10p

Corbett, J., Rice, J., Saccone, N., Goate, A., Reich, T., Foroud, T., Nurnberger, J., Edenberg, H., DePaulo, J. R. & Gershon, E., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, 1 p.

Research output: Contribution to journalArticle

Linkage disequilibrium analysis unveils evidence for a chromosome 11q23 bipolar disorder susceptibility locus

Detera-Wadleigh, S. D., Badner, J. A., Yoshikawa, T., Gershon, E. S., Sanders, A. R., Berrettini, W. H., Goldin, L. R., Nurnberger, J. I., Moses, T. Y., Turner, G. & Rollins, D. Y., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Melatonin suppression by light in euthymic bipolar and unipolar patients

Nurnberger, J. I., Adkins, S., Lahiri, D. K., Mayeda, A., Hu, K., Lewy, A., Miller, A., Bowman, E. S., Miller, M. J., Rau, L. N., Smiley, C. & Davis-Singh, D., Jun 2000, In : Archives of general psychiatry. 57, 6, p. 572-579 8 p.

Research output: Contribution to journalArticle

168 Scopus citations

Parents vs. Youth agreement on psy-chosocial variables in a semi-structured interview for genetic research

Reich, W., Fox, L., Rasmussen, E., Reich, T., Crowe, R., Edenberg, H., Hesselbrock, V., Li, T. K., Nurnberger, J., Porjesz, B., Rice, J., Schuckit, M. & Begleiter, H., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, p. 510-511 2 p.

Research output: Contribution to journalArticle

Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees

Foroud, T., Castelluccio, P. F., Koller, D. L., Edenberg, H. J., Miller, M., Bowman, E., Rau, N. L., Smiley, C., Rice, J. P., Goate, A., Armstrong, C., Bierut, L. J., Reich, T., Detera-Wadleigh, S. D., Goldin, L. R., Badner, J. A., Guroff, J. J., Gershon, E. S., McMahon, F. J., Simpson, S. & 6 others, MacKinnon, D., McInnis, M., Stine, O. C., DePaulo, J. R., Blehar, M. C. & Nurnberger, J. I., Feb 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

The familial aggregation of alcohol dependence, habitual smoking, and major depressive disorder in the collaborative study of the genetics of alcoholism

Bierut, L. J., Johnson, E. O., Breslau, N., Chase, G., Begleiter, H., Crowe, R., Hesselbrock, V., Nurnberger, J. I., Schuckit, M. & Reich, T., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, p. 463-464 2 p.

Research output: Contribution to journalArticle

Update on chromosomal locations for psychiatric disorders: Report of the interim meeting of chromosome workshop chairpersons from the VIIth World Congress of Psychiatric Genetics, Monterey; California, October 14-18, 1999

DeLisi, L. E., Craddock, N. J., Detera-Wadleigh, S., Foroud, T., Gejman, P., Kennedy, J. L., Lendon, C., Macciardi, F., McKeon, P., Mynett-Johnson, L., Nurnberger, J. I., Paterson, A., Schwab, S., Van Broeckhoven, C., Wildenauer, D. & Crow, T. J., Jun 12 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 3, p. 434-449 16 p.

Research output: Contribution to journalArticle

36 Scopus citations
1999

A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2

Detera-Wadleigh, S. D., Badner, J. A., Berrettini, W. H., Yoshikawa, T., Goldin, L. R., Turner, G., Rollins, D. Y., Moses, T., Sanders, A. R., Karkera, J. D., Esterling, L. E., Zeng, J., Ferraro, T. N., Guroff, J. J., Kazuba, D., Maxwell, M. E., Nurnberger, J. I. & Gershon, E. S., May 11 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 10, p. 5604-5609 6 p.

Research output: Contribution to journalArticle

364 Scopus citations

A preliminary study of acute responses to clamped alcohol concentration and family history of alcoholism

Ramchandani, V. A., O'Connor, S., Blekher, T., Kareken, D., Morzorati, S., Nurnberger, J. & Li, T. K., Jan 1 1999, In : Alcoholism: Clinical and Experimental Research. 23, 8, 1 p.

Research output: Contribution to journalArticle

52 Scopus citations

Chromosome 6 workshop report

Nurnberger, J. I. & Foroud, T., Jun 18 1999, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 88, 3, p. 233-238 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Description of the genetic analysis workshop 11 collaborative study on the genetics of alcoholism

Begleiter, H., Reich, T., Nurnberger, J., Li, T. K., Conneally, P. M., Edenberg, H., Crowe, R., Kuperman, S., Schuckit, M., Bloom, F., Hesselbrock, V., Porjesz, B., Cloninger, C. R., Rice, J. & Goate, A., 1999, In : Genetic epidemiology. 17, SUPPL. 1, p. S25-S30

Research output: Contribution to journalArticle

34 Scopus citations

Detection of specific protein bands with melatonin-like immunoreactivity in different cell lines and human brain regions

Lahiri, D. K., Davis, D. & Nurnberger, J. I., Nov 12 1999, In : IUBMB Life. 48, 1, p. 127-132 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Genome screen for platelet monoamine oxidase (MAO) activity

Saccone, N. L., Rice, J. P., Rochberg, N., Goate, A., Reich, T., Shears, S., Wu, W., Nurnberger, J. I., Foroud, T., Edenberg, H. J. & Li, T. K., Oct 15 1999, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 88, 5, p. 517-521 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Stress-induced changes of norepinephrine uptake sites in the locus coeruleus of C57BL/6J and DBA/2J mice: A quantitative autoradiographic study using [3H]-tomoxetine

Hwang, B. H., Kunkler, P. E., Tarricone, B. J., Hingtgen, J. N. & Nurnberger, J. I., Apr 23 1999, In : Neuroscience Letters. 265, 3, p. 151-154 4 p.

Research output: Contribution to journalArticle

23 Scopus citations
1998

A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism

Edenberg, H. J., Foroud, T., Koller, D. L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C. R., Nurnberger, J. I., Kowalczuk, M., Wu, B., Li, T. K., Conneally, P. M., Tischfield, J. A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B. & 1 others, Begleiter, H., 1998, In : Alcoholism: Clinical and Experimental Research. 22, 2, p. 505-512 8 p.

Research output: Contribution to journalArticle

98 Scopus citations

A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence

Edenberg, H. J., Reynolds, J., Koller, D. L., Begleiter, H., Bucholz, K. K., Conneally, P. M., Crowe, R., Goate, A., Hesselbrock, V., Li, T. K., Nurnberger, J. I., Porjesz, B., Reich, T., Rice, J. P., Schuckit, M., Tischfield, J. A. & Foroud, T., Aug 1998, In : Alcoholism: Clinical and Experimental Research. 22, 5, p. 1080-1085 6 p.

Research output: Contribution to journalArticle

84 Scopus citations

Anxiety proneness linked to epistatic loci in genome scan of human personality traits

Cloninger, C. R., Van Eerdewegh, P., Goate, A., Edenberg, H. J., Blangero, J., Hesselbrock, V., Reich, T., Nurnberger, J., Schuckit, M., Porjesz, B., Crowe, R., Rice, J. P., Foroud, T., Przybeck, T. R., Almasy, L., Bucholz, K., Wu, W., Shears, S., Carr, K., Crose, C. & 6 others, Willig, C., Zhao, J., Tischfield, J. A., Li, T. K., Conneally, P. M. & Begleiter, H., Jul 10 1998, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 81, 4, p. 313-317 5 p.

Research output: Contribution to journalArticle

133 Scopus citations

Chromosome 6 workshop

Nurnberger, J. I. & Foroud, T., Jan 1 1998, In : Psychiatric genetics. 8, 2, p. 79-83 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clinical relevance of the distinction between alcohol dependence with and without a physiological component

Schuckit, M. A., Smith, T. L., Daeppen, J. B., Eng, M., Li, T. K., Hesselbrock, V. M., Nurnberger, J. I. & Bucholz, K. K., Jun 13 1998, In : American Journal of Psychiatry. 155, 6, p. 733-740 8 p.

Research output: Contribution to journalArticle

83 Scopus citations