John Turchi

  • 3484 Citations
  • 35 h-Index
1991 …2019
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  • 4 Similar Profiles
DNA Medicine & Life Sciences
Cisplatin Medicine & Life Sciences
Replication Protein A Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
DNA-Activated Protein Kinase Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Repair Chemical Compounds
Proteins Medicine & Life Sciences

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NIH Grants 1995 2018

Clustered Regularly Interspaced Short Palindromic Repeats
Genome
DNA Repair
DNA
Zinc Fingers
Xeroderma Pigmentosum
DNA Damage
Lung Neoplasms
DNA Repair
Therapeutics
Recombinational DNA Repair
DNA Repair
Cisplatin
Neoplasms
Replication Protein A
Neoplasms
Cisplatin
Therapeutics
Platinum
DNA Adducts
Genomic Instability
Maintenance
Platinum
Replication Protein A
Therapeutics

Publications 1991 2019

  • 3484 Citations
  • 35 h-Index
  • 83 Article
  • 3 Chapter
  • 1 Review article

Small-molecule inhibitor screen for DNA repair proteins

Turchi, J. & VanderVere-Carozza, P. S., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 217-221 5 p. (Methods in Molecular Biology; vol. 1999).

Research output: Chapter in Book/Report/Conference proceedingChapter

DNA Repair
DNA Damage
Fluorescence Polarization
Acids
Protein Kinases

Characterization of thermally activated metalloenediyne cytotoxicity in human melanoma cells

Keller, E. J., Porter, M., Garrett, J. E., Varie, M., Wang, H., Pollok, K., Turchi, J., Zaleski, J. M. & Dynlacht, J., Aug 1 2018, In : Radiation Research. 190, 2, p. 107-116 10 p.

Research output: Contribution to journalArticle

hyperthermia
Melanoma
deoxyribonucleic acid
Temperature
Fever
17 Citations (Scopus)

Modulating DNA Repair Pathways to Improve Precision Genome Engineering

Pawelczak, K. S., Gavande, N. S., VanderVere-Carozza, P. S. & Turchi, J., Feb 16 2018, In : ACS Chemical Biology. 13, 2, p. 389-396 8 p.

Research output: Contribution to journalReview article

DNA Repair
Repair
Genes
Genome
DNA
2 Citations (Scopus)

Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein-DNA Interaction

Gavande, N. S., Vandervere-Carozza, P., Mishra, A. K., Vernon, T. L., Pawelczak, K. S. & Turchi, J., Oct 12 2017, In : Journal of Medicinal Chemistry. 60, 19, p. 8055-8070 16 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum Group A Protein
Xeroderma Pigmentosum
DNA Repair
Solubility
DNA
21 Citations (Scopus)

DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer

Sears, C., Cooney, S. A., Chin-Sinex, H., Mendonca, M. & Turchi, J., Apr 1 2016, In : DNA Repair. 40, p. 35-46 12 p.

Research output: Contribution to journalArticle

Ionizing radiation
Ionizing Radiation
Non-Small Cell Lung Carcinoma
Cisplatin
DNA Damage