Karen Pollok

  • 4572 Citations
  • 34 h-Index
1989 …2020

Research output per year

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Publications

  • 4572 Citations
  • 34 h-Index
  • 97 Article
  • 8 Review article
  • 1 Comment/debate
1989

Isolation and immunological characterization of a group of new B lymphomas from CBA mice

Udhayakumar, V., Brodeur, P. H., Rajagopalan, M. S., Zimmer, S., Pollok, K. E. & Subbarao, B., May 1989, In : Clinical Immunology and Immunopathology. 51, 2, p. 240-251 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Phosphorylation of class I but not class II MHC molecules by membrane-localized protein kinase C

Burke, T., Pollok, K., Cushley, W. & Charles Snow, E., Dec 1989, In : Molecular Immunology. 26, 12, p. 1095-1104 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
1990

Delivery of the major growth stimulus to resting B cells

Snow, E. C., DeBenedette, M. & Pollok, K. E., 1990, In : Research in Immunology. 141, 4, p. 408-412 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
1991

The development of competence in resting B cells. The induction of cyclic AMP and ornithine decarboxylase activity after direct contact between B and T helper cells

Pollok, K. E., O'Brien, V., Marshall, L., Olson, J. W., Noelle, R. J. & Snow, E. C., Jan 1 1991, In : Journal of Immunology. 146, 5, p. 1633-1641 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
12 Scopus citations
1993

Inducible T cell antigen 4-1BB: Analysis of expression and function

Pollok, K. E., Kim, Y. J., Zhou, Z., Hurtado, J., Kim, K. K., Pickard, R. T. & Kwon, B. S., Jan 1 1993, In : Journal of Immunology. 150, 3, p. 771-781 11 p.

Research output: Contribution to journalArticle

343 Scopus citations

Macrophage inflammatory protein-1α rapidly modulates its receptors and inhibits the anti-CD3 mAb-mediated proliferation of T lymphocytes

Zhou, Z., Kim, Y. J., Pollok, K., Hurtado, J., Lee, J. K., Broxmeyer, H. E. & Kwon, B. S., Jan 1 1993, In : Journal of Immunology. 151, 8, p. 4333-4341 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Molecular events in B lymphocyte activation: Consequences of signals transduced through MHC class ii molecules

Baluyut, A. R., Pollok, K. E. & Bondada, S., Apr 1993, In : Cellular Immunology. 147, 2, p. 353-366 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Novel T cell antigen 4-1BB associates with the protein tyrosine kinase p56(lck1)

Kim, Y. J., Pollok, K. E., Zhou, Z., Shaw, A., Bohlen, J. B., Fraser, M. & Kwon, B. S., Jan 1 1993, In : Journal of Immunology. 151, 3, p. 1255-1262 8 p.

Research output: Contribution to journalArticle

51 Scopus citations
1994

4‐1BB T‐cell antigen binds to mature B cells and macrophages, and costimulates anti‐μ‐primed splenic B cells

Pollok, K. E., Kim, YJ. J., Hurtado, J., Zhou, Z., Kim, K. K. & Kwon, B. S., Feb 1994, In : European Journal of Immunology. 24, 2, p. 367-374 8 p.

Research output: Contribution to journalArticle

194 Scopus citations

Functional analysis of T-cell antigen 4-1BB in activated intestinal intra-epithelial T lymphocytes

Zhou, Z., Pollok, K. E., Kim, K. K., Kim, Y. J. & Kwon, B. S., Jul 1994, In : Immunology Letters. 41, 2-3, p. 177-184 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
1995

Characterization of human homologue of 4-1BB and its ligand

Zhou, Z., Kim, S., Hurtado, J., Lee, Z. H., Kim, K. K., Pollok, K. E. & Kwon, B. S., Feb 1995, In : Immunology Letters. 45, 1-2, p. 67-73 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Potential role of 4-1BB in T cell activation: Comparison with the costimulatory molecule CD28

Hurtado, J. C., Kim, S. H., Pollok, K. E., Lee, Z. H. & Kwon, B. S., Jan 1 1995, In : Journal of Immunology. 155, 7, p. 3360-3367 8 p.

Research output: Contribution to journalArticle

153 Scopus citations

Regulation of 4‐1BB expression by cell‐cell interactions and the cytokines, interleukin‐2 and interleukin‐4

Pollok, K. E., Kim, S. H. & Kwon, B. S., Feb 1995, In : European Journal of Immunology. 25, 2, p. 488-494 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by camp

DeBenedette, M. A., Randall Chu, N., Pollok, K. E., Hurtado, J., Wade, W. F., Kwon, B. S. & Watts, T. H., Mar 1 1995, In : Journal of Experimental Medicine. 181, 3, p. 985-992 8 p.

Research output: Contribution to journalArticle

158 Scopus citations
1997

Cord blood mononuclear cell transformation assay for screening for the presence of epstein-barr virus

Lucas, K. G., Burton, R., Heilman, D. K., Pollok, K. & Emanuel, D., Dec 1997, In : Journal of Hematotherapy and Stem Cell Research. 6, 6, p. 587-590 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

High gene transfer efficiency utilizing recombinant fibronectin fragments in cd3/c d28-expanded peripheral blood lymphocytes prom an adenosine-deaminase-defioent patient

Pollok, K. E., Hanenberg, H., Nobhrt, T. W., Schroeder, W. L., Asada, K., Kato, I., Emanuel, D. & Williaims, D. A., Dec 1 1997, In : Experimental Hematology. 25, 8, 1 p.

Research output: Contribution to journalArticle

Post-transplant EBV induced lymphoproliferative disorders

Lucas, K. G., Pollok, K. E. & Emanuel, D. J., Jan 1 1997, In : Leukemia and Lymphoma. 25, 1-2, p. 1-8 8 p.

Research output: Contribution to journalReview article

51 Scopus citations

Treatment of posttransplant lymphoproliferative disease in the central nervous system of a lung transplant recipient using allogeneic leukocytes

Emanuel, D. J., Lucas, K. G., Mallory, G. B., Edwards-Brown, M. K., Pollok, K. E., Conrad, P. D., Robertson, K. A. & Smith, F. O., Jun 15 1997, In : Transplantation. 63, 11, p. 1691-1694 4 p.

Research output: Contribution to journalArticle

52 Scopus citations
1998

High-efficiency gene transfer into normal and adenosine deaminase- deficient T lymphocytes is mediated by transduction on recombinant fibronectin fragments

Pollok, K. E., Hanenberg, H., Noblitt, T. W., Schroeder, W. L., Kato, I., Emanuel, D. & Williams, D. A., Jun 1 1998, In : Journal of virology. 72, 6, p. 4882-4892 11 p.

Research output: Contribution to journalArticle

109 Scopus citations
1999

CD4+ Epstein-Barr virus-specific cytotoxic T-lymphocytes from human umbilical cord blood

Sun, Q., Burton, R. L., Pollok, K. E., Emanuel, D. J. & Lucas, K. G., Aug 1 1999, In : Cellular Immunology. 195, 2, p. 81-88 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Costimulation of transduced T lymphocytes via T cell receptor-CD3 complex and CD28 leads to increased transcription of integrated retrovirus

Pollok, K. E., Van Der Loo, J. C. M., Cooper, R. J., Kennedy, L. & Williams, D. A., Sep 1 1999, In : Human gene therapy. 10, 13, p. 2221-2236 16 p.

Research output: Contribution to journalArticle

53 Scopus citations
17 Scopus citations

Green fluorescent protein as a selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes

Dardalhon, V., Noraz, N., Pollok, K., Rebouissou, C., Boyer, M., Bakker, A. Q., Spits, H. & Taylor, N., Jan 1 1999, In : Human gene therapy. 10, 1, p. 5-14 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Simultaneous ex vivo expansion of cytomegalovirus and Epstein-Barr virus-specific cytotoxic T lymphocytes using B-lymphoblastoid cell lines expressing cytomegalovirus pp65

Sun, Q., Pollok, K. E., Burton, R. L., Dai, L. J., Britt, W., Emanuel, D. J. & Lucas, K. G., Nov 1 1999, In : Blood. 94, 9, p. 3242-3250 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

Simultaneous infection with retroviruses pseudotyped with different envelope proteins bypasses viral receptor interference associated with colocalization of gp70 and target cells on fibronectin CH-296

MacNeill, E. C., Hanenberg, H., Pollok, K. E., Van Der Loo, J. C. M., Bierhuizen, M. F. A., Wagemaker, G. & Williams, D. A., 1999, In : Journal of virology. 73, 5, p. 3960-3967 8 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations
2001

Differential transduction efficiency of SCID-repopulating cells derived from umbilical cord blood and granulocyte colony-stimulating factor-mobilized peripheral blood

Pollok, K. E., Van der Loo, J. C. M., Cooper, R. J., Hartwell, J. R., Miles, K. R., Breese, R., Williams, E. P., Montel, A., Seshadri, R., Hanenberg, H. & Williams, D. A., Nov 20 2001, In : Human gene therapy. 12, 17, p. 2095-2108 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Interleukin-5 inhibition of biliary cell chloride currents and bile flow

McGill, J. M., Yen, M. S., Cummings, O. W., Alpini, G., Lesage, G., Pollok, K. E., Miller, B., Engle, S. K. & Stansfield, A. P., Apr 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 280, 4 43-4, p. G738-G745

Research output: Contribution to journalArticle

12 Scopus citations
2002

Phenotypic correction of primary Fanconi anemia T cells with retroviral vectors as a diagnostic tool

Hanenberg, H., Pollok, K. E., Vieten, L., Verlander, P. C., Leurs, C., Cooper, R. J., Göttsche, K., Haneline, L., Clapp, D. W., Lobitz, S., Williams, D. A. & Auerbach, A. D., 2002, In : Experimental Hematology. 30, 5, p. 410-420 11 p.

Research output: Contribution to journalArticle

75 Scopus citations
2003

A theoretically optimized method for cord blood stem cell cryopreservation

Woods, E. J., Liu, J., Pollok, K., Hartwell, J., Smith, F. O., Williams, D. A., Yoder, M. C. & Critser, J. K., Jun 1 2003, In : Journal of Hematotherapy and Stem Cell Research. 12, 3, p. 341-350 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells

Leurs, C., Jansen, M., Pollok, K. E., Heinkelein, M., Schmidt, M., Wissler, M., Lindemann, D., Von Kalle, C., Rethwilm, A., Williams, D. A. & Hanenberg, H., Apr 10 2003, In : Human gene therapy. 14, 6, p. 509-519 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Hematopoietic expression of O6-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O6-benzylguanine and 1,3-bis-(2-chloroethyl)-1- nitrosourea

Kreklau, E. L., Pollok, K. E., Bailey, B. J., Liu, N., Hartwell, J. R., Williams, D. A. & Erickson, L. C., Dec 1 2003, In : Molecular cancer therapeutics. 2, 12, p. 1321-1329 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

In vivo protection of hematopoietic cells from alkylator-mediated DNA damage.

Pollok, K. E., Jul 2003, In : Current hematology reports. 2, 4, p. 341-347 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

In Vivo Selection of Human Hematopoietic Cells in a Xenograft Model Using Combined Pharmacologic and Genetic Manipulations

Pollok, K. E., Hartwell, J. R., Braber, A., Cooper, R. J., Jansen, M., Ragg, S., Bailey, B. J., Erickson, L. C., Kreklau, E. L. & Williams, D. A., Dec 10 2003, In : Human gene therapy. 14, 18, p. 1703-1714 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
2004

Evaluation of Plasmid DNA Removal from Lentiviral Vectors by Benzonase Treatment

Sastry, L., Xu, Y., Cooper, R., Pollok, K. & Cornetta, K., Feb 1 2004, In : Human gene therapy. 15, 2, p. 221-226 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

Ingram, D. A., Mead, L. E., Tanaka, H., Meade, V., Fenoglio, A., Mortell, K., Pollok, K., Ferkowicz, M. J., Gilley, D. & Yoder, M. C., Nov 1 2004, In : Blood. 104, 9, p. 2752-2760 9 p.

Research output: Contribution to journalArticle

1166 Scopus citations
2005
16 Scopus citations

Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents

Cai, S., Xu, Y., Cooper, R. J., Ferkowiez, M. J., Hartwell, J. R., Pollok, K. E. & Kelley, M. R., Apr 15 2005, In : Cancer Research. 65, 8, p. 3319-3327 9 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

Real-Time PCR: An effective tool for measuring transduction efficiency in human hematopoietic progenitor cells

Villella, A. D., Yao, J., Getty, R. R., Juliar, B. E., Yiannoutsos, C., Hartwell, J. R., Cai, S., Sadat, M. A., Cornetta, K., Williams, D. A. & Pollok, K. E., Mar 2005, In : Molecular Therapy. 11, 3, p. 483-491 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2006

G2 Cell Cycle Arrest and Cyclophilin A in Lentiviral Gene Transfer

Zhang, S., Joseph, G., Pollok, K., Berthoux, L., Sastry, L., Luban, J. & Cornetta, K., Oct 1 2006, In : Molecular Therapy. 14, 4, p. 546-554 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

In Vivo Effects of Myeloablative Alkylator Therapy on Survival and Differentiation of MGMTP140K-Transduced Human G-CSF-Mobilized Peripheral Blood Cells

Cai, S., Hartwell, J. R., Cooper, R. J., Juliar, B. E., Kreklau, E., Abonour, R., Goebel, W. S. & Pollok, K. E., May 1 2006, In : Molecular Therapy. 13, 5, p. 1016-1026 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
16 Scopus citations
2007

Chemotherapeutic selectivity conferred by selenium: A role for p53-dependent DNA repair

Fischer, J. L., Mihelc, E. M., Pollok, K. E. & Smith, M. L., Jan 2007, In : Molecular cancer therapeutics. 6, 1, p. 355-361 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Cord blood stem cell cryopreservation

Woods, E. J., Pollok, K. E., Byers, M. A., Perry, B. C., Purtteman, J., Heimfeld, S. & Gao, D., Aug 1 2007, In : Transfusion Medicine and Hemotherapy. 34, 4, p. 276-285 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice

Campbell, T. B., Hangoc, G., Liu, Y., Pollok, K. & Broxmeyer, H. E., Jun 2007, In : Stem cells and development. 16, 3, p. 347-353 7 p.

Research output: Contribution to journalArticle

94 Scopus citations
2008

A novel competitive repopulation strategy to quantitate engraftment of ex vivo manipulated murine marrow cells in submyeloablated hosts

Wyss, B. K., Meyers, J. L., Sinn, A. L., Cai, S., Pollok, K. E. & Goebel, W. S., Jan 1 2008, In : Experimental Hematology. 36, 4, p. 513-521 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Generation of stable vector-producing cells for retroviral vectors

Cornetta, K., Pollok, K. E. & Miller, A. D., Apr 1 2008, In : Cold Spring Harbor protocols. 3, 4

Research output: Contribution to journalArticle

1 Scopus citations

Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34+ NOD/SCID-repopulating cells

Liu, Y., Hangoc, G., Campbell, T. B., Goodman, M., Tao, W., Pollok, K., Srour, E. F. & Broxmeyer, H. E., Aug 1 2008, In : Experimental Hematology. 36, 8, p. 947-956 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMTP140K vector

Cai, S., Ernstberger, A., Wang, H., Bailey, B. J., Hartwell, J. R., Sinn, A. L., Eckermann, O., Linka, Y., Goebel, W. S., Hanenberg, H. & Pollok, K. E., Mar 2008, In : Experimental Hematology. 36, 3, p. 283-292 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Retroviral vector production by transient transfection

Cornetta, K., Pollok, K. E. & Miller, A. D., Apr 1 2008, In : Cold Spring Harbor protocols. 3, 4

Research output: Contribution to journalArticle

2 Scopus citations