Karen Pollok

  • 4572 Citations
  • 34 h-Index
1989 …2020

Research output per year

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Publications

  • 4572 Citations
  • 34 h-Index
  • 97 Article
  • 8 Review article
  • 1 Comment/debate

4‐1BB T‐cell antigen binds to mature B cells and macrophages, and costimulates anti‐μ‐primed splenic B cells

Pollok, K. E., Kim, YJ. J., Hurtado, J., Zhou, Z., Kim, K. K. & Kwon, B. S., Feb 1994, In : European Journal of Immunology. 24, 2, p. 367-374 8 p.

Research output: Contribution to journalArticle

194 Scopus citations

Acridine Orange as a Novel Photosensitizer for Photodynamic Therapy in Glioblastoma

Osman, H., Elsahy, D., Saadatzadeh, M. R., Pollok, K. E., Yocom, S., Hattab, E. M., Georges, J. & Cohen-Gadol, A. A., Jun 2018, In : World Neurosurgery. 114, p. e1310-e1315

Research output: Contribution to journalArticle

7 Scopus citations

Activation of death-associated protein kinase in human peritumoral tissue: A potential therapeutic target

Gao, X., Wang, H., Pollok, K. E., Chen, J. & Cohen-Gadol, A. A., Oct 1 2015, In : Journal of Clinical Neuroscience. 22, 10, p. 1655-1660 6 p., 6063.

Research output: Contribution to journalArticle

2 Scopus citations

A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo

Handlogten, M. W., Serezani, A. P., Sinn, A. L., Pollok, K. E., Kaplan, M. H. & Bilgicer, B., Mar 1 2014, In : Journal of Immunology. 192, 5, p. 2035-2041 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

A novel competitive repopulation strategy to quantitate engraftment of ex vivo manipulated murine marrow cells in submyeloablated hosts

Wyss, B. K., Meyers, J. L., Sinn, A. L., Cai, S., Pollok, K. E. & Goebel, W. S., Jan 1 2008, In : Experimental Hematology. 36, 4, p. 513-521 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential

Estes, M. L., Mund, J. A., Mead, L. E., Prater, D. N., Cai, S., Wang, H., Pollok, K. E., Murphy, M. P., An, C. S. T., Srour, E. F., Ingram, D. A. & Case, J., Sep 2010, In : Cytometry Part A. 77, 9, p. 831-839 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

A theoretically optimized method for cord blood stem cell cryopreservation

Woods, E. J., Liu, J., Pollok, K., Hartwell, J., Smith, F. O., Williams, D. A., Yoder, M. C. & Critser, J. K., Jun 1 2003, In : Journal of Hematotherapy and Stem Cell Research. 12, 3, p. 341-350 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

CD4+ Epstein-Barr virus-specific cytotoxic T-lymphocytes from human umbilical cord blood

Sun, Q., Burton, R. L., Pollok, K. E., Emanuel, D. J. & Lucas, K. G., Aug 1 1999, In : Cellular Immunology. 195, 2, p. 81-88 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

C-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells

Day, T. W., Sinn, A. L., Huang, S., Pollok, K. E., Sandusky, G. E. & Safa, A. R., Oct 1 2009, In : Anticancer Research. 29, 10, p. 3883-3886 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Characterization of human homologue of 4-1BB and its ligand

Zhou, Z., Kim, S., Hurtado, J., Lee, Z. H., Kim, K. K., Pollok, K. E. & Kwon, B. S., Feb 1995, In : Immunology Letters. 45, 1-2, p. 67-73 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Characterization of thermally activated metalloenediyne cytotoxicity in human melanoma cells

Keller, E. J., Porter, M., Garrett, J. E., Varie, M., Wang, H., Pollok, K. E., Turchi, J. J., Zaleski, J. M. & Dynlacht, J. R., Aug 1 2018, In : Radiation research. 190, 2, p. 107-116 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Chemotherapeutic selectivity conferred by selenium: A role for p53-dependent DNA repair

Fischer, J. L., Mihelc, E. M., Pollok, K. E. & Smith, M. L., Jan 2007, In : Molecular cancer therapeutics. 6, 1, p. 355-361 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Combination therapy in a xenograft model of glioblastoma: Enhancement of the antitumor activity of temozolomide by an MDM2 antagonist

Wang, H., Cai, S., Bailey, B. J., Saadatzadeh, M. R., Ding, J., Tonsing-Carter, E., Georgiadis, T. M., Gunter, T. Z., Long, E. C., Minto, R. E., Gordon, K. R., Sen, S. E., Cai, W., Eitel, J. A., Waning, D. L., Bringman, L. R., Wells, C. D., Murray, M. E., Sarkaria, J. N., Gelbert, L. M. & 5 others, Jones, D. R., Cohen-Gadol, A. A., Mayo, L. D., Shannon, H. E. & Pollok, K. E., Feb 2017, In : Journal of neurosurgery. 126, 2, p. 446-459 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells

Leurs, C., Jansen, M., Pollok, K. E., Heinkelein, M., Schmidt, M., Wissler, M., Lindemann, D., Von Kalle, C., Rethwilm, A., Williams, D. A. & Hanenberg, H., Apr 10 2003, In : Human gene therapy. 14, 6, p. 509-519 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Cord blood mononuclear cell transformation assay for screening for the presence of epstein-barr virus

Lucas, K. G., Burton, R., Heilman, D. K., Pollok, K. & Emanuel, D., Dec 1997, In : Journal of Hematotherapy and Stem Cell Research. 6, 6, p. 587-590 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cord blood stem cell cryopreservation

Woods, E. J., Pollok, K. E., Byers, M. A., Perry, B. C., Purtteman, J., Heimfeld, S. & Gao, D., Aug 1 2007, In : Transfusion Medicine and Hemotherapy. 34, 4, p. 276-285 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Costimulation of transduced T lymphocytes via T cell receptor-CD3 complex and CD28 leads to increased transcription of integrated retrovirus

Pollok, K. E., Van Der Loo, J. C. M., Cooper, R. J., Kennedy, L. & Williams, D. A., Sep 1 1999, In : Human gene therapy. 10, 13, p. 2221-2236 16 p.

Research output: Contribution to journalArticle

53 Scopus citations

Delivery of the major growth stimulus to resting B cells

Snow, E. C., DeBenedette, M. & Pollok, K. E., 1990, In : Research in Immunology. 141, 4, p. 408-412 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Design, synthesis, and evaluation of curcumin-derived arylheptanoids for glioblastoma and neuroblastoma cytotoxicity

Campos, C. A., Gianino, J. B., Bailey, B. J., Baluyut, M. E., Wiek, C., Hanenberg, H., Shannon, H. E., Pollok, K. E. & Ashfeld, B. L., Dec 15 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 24, p. 6874-6878 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Differential transduction efficiency of SCID-repopulating cells derived from umbilical cord blood and granulocyte colony-stimulating factor-mobilized peripheral blood

Pollok, K. E., Van der Loo, J. C. M., Cooper, R. J., Hartwell, J. R., Miles, K. R., Breese, R., Williams, E. P., Montel, A., Seshadri, R., Hanenberg, H. & Williams, D. A., Nov 20 2001, In : Human gene therapy. 12, 17, p. 2095-2108 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer

Solzak, J. P., Atale, R. V., Hancock, B. A., Sinn, A. L., Pollok, K. E., Jones, D. R. & Radovich, M., Dec 1 2017, In : npj Breast Cancer. 3, 1, 0016.

Research output: Contribution to journalArticle

14 Scopus citations

Emerging targets for glioblastoma stem cell therapy

Safa, A. R., Saadatzadeh, M. R., Cohen-Gadol, A. A., Pollok, K. E. & Bijangi-Vishehsaraei, K., 2016, In : Journal of Biomedical Research. 30, 1, p. 19-31 13 p.

Research output: Contribution to journalReview article

23 Scopus citations

Enhanced anticancer properties of lomustine in conjunction with docosahexaenoic acid in glioblastoma cell lines

Harvey, K. A., Xu, Z., Saaddatzadeh, M. R., Wang, H., Pollok, K., Cohen-Gadol, A. A. & Siddiqui, R. A., Mar 2015, In : Journal of neurosurgery. 122, 3, p. 547-556 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Enhanced homing and engraftment of fresh but not ex vivo cultured murine marrow cells in submyeloablated hosts following CD26 inhibition by Diprotin A

Wyss, B. K., Donnelly, A. F. W., Zhou, D., Sinn, A. L., Pollok, K. E. & Goebel, W. S., Jul 1 2009, In : Experimental Hematology. 37, 7, p. 814-823 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Erratum: Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo (Oncogene (2016) 35 (783-792) DOI:10.1038/onc.2015.215)

Huang, W., Dong, Z., Chen, Y., Wang, F., Wang, C. J., Peng, H., He, Y., Hangoc, G., Pollok, K., Sandusky, G., Fu, X. Y., Broxmeyer, H. E., Zhang, Z. Y., Liu, J. Y. & Zhang, J. T., Feb 11 2016, In : Oncogene. 35, 6, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Evaluation of Plasmid DNA Removal from Lentiviral Vectors by Benzonase Treatment

Sastry, L., Xu, Y., Cooper, R., Pollok, K. & Cornetta, K., Feb 1 2004, In : Human gene therapy. 15, 2, p. 221-226 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

Exploring a structural protein-drug interactome for new therapeutics in lung cancer

Peng, X., Wang, F., Li, L., Bum-Erdene, K., Xu, D., Wang, B., Sinn, A. A., Pollok, K. E., Sandusky, G. E., Li, L., Turchi, J. J., Jalal, S. I. & Meroueh, S. O., Mar 2014, In : Molecular BioSystems. 10, 3, p. 581-591 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
17 Scopus citations

Functional analysis of T-cell antigen 4-1BB in activated intestinal intra-epithelial T lymphocytes

Zhou, Z., Pollok, K. E., Kim, K. K., Kim, Y. J. & Kwon, B. S., Jul 1994, In : Immunology Letters. 41, 2-3, p. 177-184 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

G2 Cell Cycle Arrest and Cyclophilin A in Lentiviral Gene Transfer

Zhang, S., Joseph, G., Pollok, K., Berthoux, L., Sastry, L., Luban, J. & Cornetta, K., Oct 1 2006, In : Molecular Therapy. 14, 4, p. 546-554 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Gene co-expression networks restructured gene fusion in rhabdomyosarcoma cancers

Helm, B. R., Zhan, X., Pandya, P. H., Murray, M. E., Pollok, K. E., Renbarger, J. L., Ferguson, M. J., Han, Z., Ni, D., Zhang, J. & Huang, K., Sep 2019, In : Genes. 10, 9, 665.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Generation of stable vector-producing cells for retroviral vectors

Cornetta, K., Pollok, K. E. & Miller, A. D., Apr 1 2008, In : Cold Spring Harbor protocols. 3, 4

Research output: Contribution to journalArticle

1 Scopus citations

Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs

Safa, A. R., Saadatzadeh, M. R., Cohen-Gadol, A. A., Pollok, K. E. & Bijangi-Vishehsaraei, K., Jun 1 2015, In : Genes and Diseases. 2, 2, p. 152-163 12 p.

Research output: Contribution to journalReview article

80 Scopus citations

Green fluorescent protein as a selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes

Dardalhon, V., Noraz, N., Pollok, K., Rebouissou, C., Boyer, M., Bakker, A. Q., Spits, H. & Taylor, N., Jan 1 1999, In : Human gene therapy. 10, 1, p. 5-14 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Hematopoietic expression of O6-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O6-benzylguanine and 1,3-bis-(2-chloroethyl)-1- nitrosourea

Kreklau, E. L., Pollok, K. E., Bailey, B. J., Liu, N., Hartwell, J. R., Williams, D. A. & Erickson, L. C., Dec 1 2003, In : Molecular cancer therapeutics. 2, 12, p. 1321-1329 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

High-efficiency gene transfer into normal and adenosine deaminase- deficient T lymphocytes is mediated by transduction on recombinant fibronectin fragments

Pollok, K. E., Hanenberg, H., Noblitt, T. W., Schroeder, W. L., Kato, I., Emanuel, D. & Williams, D. A., Jun 1 1998, In : Journal of virology. 72, 6, p. 4882-4892 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

High gene transfer efficiency utilizing recombinant fibronectin fragments in cd3/c d28-expanded peripheral blood lymphocytes prom an adenosine-deaminase-defioent patient

Pollok, K. E., Hanenberg, H., Nobhrt, T. W., Schroeder, W. L., Asada, K., Kato, I., Emanuel, D. & Williaims, D. A., Dec 1 1997, In : Experimental Hematology. 25, 8, 1 p.

Research output: Contribution to journalArticle

How old is too old? In vivo engraftment of human peripheral bloodstem cells cryopreserved for up to 18 years - implications for clinical transplantation and stability programs

Underwood, J., Rahim, M., West, C., Britton, R., Skipworth, E., Graves, V., Sexton, S., Harris, H., Schwering, D., Sinn, A., Pollok, K. E., Robertson, K. A., Goebel, W. S. & Hege, K. M., May 26 2020, In : World Journal of Stem Cells. 12, 5, p. 359-367 9 p.

Research output: Contribution to journalArticle

Open Access

Humanized bone marrow mouse model as a preclinical tool to assess therapy-mediated hematotoxicity

Cai, S., Wang, H., Bailey, B., Ernstberger, A., Juliar, B. E., Sinn, A. L., Chan, R. J., Jones, D. R., Mayo, L. D., Baluyut, A. R., Goebel, W. S. & Pollok, K. E., Apr 15 2011, In : Clinical Cancer Research. 17, 8, p. 2195-2206 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Human proangiogenic circulating hematopoietic stem and progenitor cells promote tumor growth in an orthotopic melanoma xenograft model

Mund, J. A., Shannon, H., Sinn, A. L., Cai, S., Wang, H., Pradhan, K. R., Pollok, K. E. & Case, J., Oct 2013, In : Angiogenesis. 16, 4, p. 953-962 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Hypoxia-inducible factor-1α regulates CD55 in airway epithelium

Pandya, P. H., Fisher, A. J., Mickler, E. A., Temm, C. J., Lipking, K. P., Gracon, A., Rothhaar, K., Sandusky, G. E., Murray, M., Pollok, K., Renbarger, J., Blum, J. S., Lahm, T. & Wilkes, D. S., Dec 2016, In : American journal of respiratory cell and molecular biology. 55, 6, p. 889-898 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
23 Scopus citations

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

Ingram, D. A., Mead, L. E., Tanaka, H., Meade, V., Fenoglio, A., Mortell, K., Pollok, K., Ferkowicz, M. J., Gilley, D. & Yoder, M. C., Nov 1 2004, In : Blood. 104, 9, p. 2752-2760 9 p.

Research output: Contribution to journalArticle

1166 Scopus citations

Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34+ NOD/SCID-repopulating cells

Liu, Y., Hangoc, G., Campbell, T. B., Goodman, M., Tao, W., Pollok, K., Srour, E. F. & Broxmeyer, H. E., Aug 1 2008, In : Experimental Hematology. 36, 8, p. 947-956 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Impact of APE1/ref-1 redox inhibition on pancreatic tumor growth

Fishel, M. L., Jiang, Y., Rajeshkumar, N. V., Scandura, G., Sinn, A. L., He, Y., Shen, C., Jones, D. R., Pollok, K. E., Ivan, M., Maitra, A. & Kelley, M. R., Sep 2011, In : Molecular cancer therapeutics. 10, 9, p. 1698-1708 11 p.

Research output: Contribution to journalArticle

56 Scopus citations

Inducible T cell antigen 4-1BB: Analysis of expression and function

Pollok, K. E., Kim, Y. J., Zhou, Z., Hurtado, J., Kim, K. K., Pickard, R. T. & Kwon, B. S., Jan 1 1993, In : Journal of Immunology. 150, 3, p. 771-781 11 p.

Research output: Contribution to journalArticle

343 Scopus citations

Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice

Campbell, T. B., Hangoc, G., Liu, Y., Pollok, K. & Broxmeyer, H. E., Jun 2007, In : Stem cells and development. 16, 3, p. 347-353 7 p.

Research output: Contribution to journalArticle

94 Scopus citations

Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma

Cheng, L., Pandya, P. H., Liu, E., Chandra, P., Wang, L., Murray, M. E., Carter, J., Ferguson, M., Saadatzadeh, M. R., Bijangi-Visheshsaraei, K., Marshall, M., Li, L., Pollok, K. E. & Renbarger, J. L., Jan 31 2019, In : BMC Medical Genomics. 12, 23.

Research output: Contribution to journalArticle

8 Scopus citations

Interleukin-5 inhibition of biliary cell chloride currents and bile flow

McGill, J. M., Yen, M. S., Cummings, O. W., Alpini, G., Lesage, G., Pollok, K. E., Miller, B., Engle, S. K. & Stansfield, A. P., Apr 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 280, 4 43-4, p. G738-G745

Research output: Contribution to journalArticle

12 Scopus citations

In Vivo Effects of Myeloablative Alkylator Therapy on Survival and Differentiation of MGMTP140K-Transduced Human G-CSF-Mobilized Peripheral Blood Cells

Cai, S., Hartwell, J. R., Cooper, R. J., Juliar, B. E., Kreklau, E., Abonour, R., Goebel, W. S. & Pollok, K. E., May 1 2006, In : Molecular Therapy. 13, 5, p. 1016-1026 11 p.

Research output: Contribution to journalArticle

13 Scopus citations