Kenneth Dunn

  • 4526 Citations
  • 35 h-Index
1988 …2020
If you made any changes in Pure, your changes will be visible here soon.

Publications 1988 2019

  • 4526 Citations
  • 35 h-Index
  • 85 Article
  • 16 Conference contribution
  • 1 Conference article
  • 1 Editorial
2019

A simple automated method for continuous fieldwise measurement of microvascular hemodynamics

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A. J., Klaunig, J. E., Glazier, J. A. & Dunn, K., May 1 2019, In : Microvascular Research. 123, p. 7-13 7 p.

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Hemodynamics
Motion Pictures
Blood Vessels
Spreadsheets

Automatic segmentation of intravital fluorescence microscopy images by K-means clustering of FLIM phasors

Zhang, Y., Hato, T., Dagher, P., Nichols, E. L., Smith, C. J., Dunn, K. & Howard, S. S., Aug 15 2019, In : Optics Letters. 44, 16, p. 3928-3931 4 p.

Research output: Contribution to journalArticle

microscopy
life (durability)
fluorescence
marking
machine learning

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

Reissaus, C. A., Piñeros, A. R., Twigg, A. N., Orr, K. S., Conteh, A. M., Martinez, M. M., Kamocka, M., Day, R., Tersey, S. A., Mirmira, R., Dunn, K. & Linnemann, A., Dec 1 2019, In : Scientific Reports. 9, 1, 8449.

Research output: Contribution to journalArticle

Open Access
Biosensing Techniques
Cell Biology
Cell Physiological Phenomena
Aptitude
Calcium Signaling

Center-extraction-based three dimensional nuclei instance segmentation of fluorescence microscopy images

Ho, D. J., Han, S., Fu, C., Salama, P., Dunn, K. W. & Delp, E. J., May 2019, 2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 8834516. (2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Fluorescence Microscopy
Microscopic examination
Tissue
Microscopy

Nuclei counting in microscopy images with three dimensional generative adversarial networks

Han, S., Lee, S., Fu, C., Salama, P., Dunn, K. & Delp, E. J., Jan 1 2019, Medical Imaging 2019: Image Processing. Landman, B. A., Angelini, E. D., Angelini, E. D. & Angelini, E. D. (eds.). SPIE, 109492Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10949).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Three-Dimensional Imaging
Fluorescence microscopy
Fluorescence Microscopy
Microscopy
Microscopic examination
2018
1 Citation (Scopus)

Intravital multiphoton microscopy with fluorescent bile salts in rats as an in vivo biomarker for hepatobiliary transport inhibition

Ryan, J., Morgan, R. E., Chen, Y., Volak, L. P., Dunn, R. T. & Dunn, K., May 1 2018, In : Drug Metabolism and Disposition. 46, 5, p. 704-718 15 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Biomarkers
Intravital Microscopy
Pharmaceutical Preparations
Chemical and Drug Induced Liver Injury
3 Citations (Scopus)

Kinetic analysis of vasculogenesis quantifies dynamics of vasculogenesis and angiogenesis in vitro

Varberg, K. M., Winfree, S., Dunn, K. & Haneline, L., Jan 31 2018, In : Journal of Visualized Experiments. 2018, 131, e57044.

Research output: Contribution to journalArticle

Medical problems
Kinetics
Network components
Diabetes Mellitus
Endothelial cells
3 Citations (Scopus)

Live-Animal Imaging of Renal Function by Multiphoton Microscopy

Dunn, K., Sutton, T. & Sandoval, R. M., Jan 18 2018, In : Current Protocols in Cytometry. 83, p. 12.9.1-12.9.25

Research output: Contribution to journalArticle

Microscopy
Microscopic examination
Animals
Kidney
Fluorescent Dyes
3 Citations (Scopus)

Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models

Fu, X., Sluka, J. P., Clendenon, S. G., Dunn, K., Wang, Z., Klaunig, J. E. & Glazier, J. A., Sep 1 2018, In : PLoS One. 13, 9, e0198060.

Research output: Contribution to journalArticle

Xenobiotics
xenobiotics
Metabolism
Liver
liver
1 Citation (Scopus)

Nuclei detection and segmentation of fluorescence microscopy images using three dimensional convolutional neural networks

Ho, D. J., Fu, C., Salama, P., Dunn, K. & Delp, E. J., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, Vol. 2018-April. p. 418-422 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Three-Dimensional Imaging
Fluorescence microscopy
Fluorescence Microscopy
Neural networks
Microscopy
1 Citation (Scopus)

Quantitative Large-Scale Three-Dimensional Imaging of Human Kidney Biopsies: A Bridge to Precision Medicine in Kidney Disease

Winfree, S., Dagher, P., Dunn, K., Eadon, M., Ferkowicz, M., Barwinska, D., Kelly, K., Sutton, T. & Ashkar (El-Achkar), T., Jun 5 2018, (Accepted/In press) In : Nephron. p. 1-6 6 p.

Research output: Contribution to journalArticle

Precision Medicine
Three-Dimensional Imaging
Kidney Diseases
Kidney
Biopsy

Segmentation of biological images containing multitarget labeling using the jelly filling framework

Gadgil, N. J., Salama, P., Dunn, K. & Delp, E. J., Oct 1 2018, In : Journal of Medical Imaging. 5, 4, 044006.

Research output: Contribution to journalArticle

Three-Dimensional Imaging
Fluorescence Microscopy
Artifacts
1 Citation (Scopus)

Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease

Swallow, E. A., Aref, M. W., Chen, X. N., Byiringiro, I., Hammond, M. A., McCarthy, B. P., Territo, P., Kamocka, M., Winfree, S., Dunn, K., Moe, S. & Allen, M., Jun 11 2018, (Accepted/In press) In : Osteoporosis International. p. 1-8 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Chronic Renal Insufficiency
Tibia
Kidney
Bone and Bones
4 Citations (Scopus)

Three dimensional fluorescence microscopy image synthesis and segmentation

Fu, C., Lee, S., Ho, D. J., Han, S., Salama, P., Dunn, K. & Delp, E. J., Dec 13 2018, Proceedings - 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2018. IEEE Computer Society, Vol. 2018-June. p. 2302-2310 9 p. 8575470

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Image quality
Microscopic examination
Tissue
Deep learning
2 Citations (Scopus)

Tubule segmentation of fluorescence microscopy images based on convolutional neural networks with inhomogeneity correction

Lee, S., Fu, C., Salama, P., Dunn, K. & Delp, E. J., Jan 1 2018, In : IS and T International Symposium on Electronic Imaging Science and Technology. Part F138654, S11.

Research output: Contribution to journalConference article

Fluorescence microscopy
inhomogeneity
microscopy
Neural networks
fluorescence
2017
2 Citations (Scopus)

Boundary segmentation for fluorescence microscopy using steerable filters

Ho, D. J., Salama, P., Dunn, K. & Delp, E. J., 2017, Medical Imaging 2017: Image Processing. SPIE, Vol. 10133. 101330E

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Fluorescence Microscopy
microscopy
filters
fluorescence

Imaging cell biology and physiology in vivo using intravital microscopy

Dunn, K. & Day, R., Sep 1 2017, In : Methods. 128, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Cell Physiological Phenomena
Cell Biology
Intravital Microscopy
2 Citations (Scopus)

Kinetic analyses of vasculogenesis inform mechanistic studies

Varberg, K. M., Winfree, S., Chu, C., Tu, W., Blue, E. K., Gohn, C. R., Dunn, K. & Haneline, L., Apr 7 2017, In : American Journal of Physiology - Cell Physiology. 312, 4, p. C446-C458

Research output: Contribution to journalArticle

Diabetes Mellitus
Fiji
Maternal Exposure
Cell Movement
Stem Cells
2 Citations (Scopus)

Large-scale 3-dimensional quantitative imaging of tissues: State-of-the-art and translational implications

Winfree, S., Ferkowicz, M. J., Dagher, P., Kelly, K., Eadon, M., Sutton, T., Markel, T. A., Yoder, M., Dunn, K. & Ashkar (El-Achkar), T., 2017, (Accepted/In press) In : Translational Research.

Research output: Contribution to journalArticle

Tissue
Imaging techniques
Research Personnel
Technology
Precision Medicine
6 Citations (Scopus)

Nuclei segmentation of fluorescence microscopy images using convolutional neural networks

Fu, C., Ho, D. J., Han, S., Salama, P., Dunn, K. & Delp, E. J., Jun 15 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging, ISBI 2017. IEEE Computer Society, p. 704-708 5 p. 7950617

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Fluorescence Microscopy
Cytology
Tissue
Neural networks
4 Citations (Scopus)

Nuclei Segmentation of Fluorescence Microscopy Images Using Three Dimensional Convolutional Neural Networks

Ho, D. J., Fu, C., Salama, P., Dunn, K. & Delp, E. J., Aug 22 2017, Proceedings - 30th IEEE Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2017. IEEE Computer Society, Vol. 2017-July. p. 834-842 9 p. 8014850

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Tissue
Neural networks
Microscopic examination
Photons
7 Citations (Scopus)

Quantitative three-dimensional tissue cytometry to study kidney tissue and resident immune cells

Winfree, S., Khan, S., Micanovic, R., Eadon, M., Kelly, K., Sutton, T., Phillips, C., Dunn, K. & Ashkar (El-Achkar), T., Jul 1 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2108-2118 11 p.

Research output: Contribution to journalArticle

Kidney
Flow Cytometry
Software
Biopsy
Spatial Analysis
6 Citations (Scopus)

Segmentation of fluorescence microscopy images using three dimensional active contours with inhomogeneity correction

Lee, S., Salama, P., Dunn, K. & Delp, E. J., Jun 15 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging, ISBI 2017. IEEE Computer Society, p. 709-713 5 p. 7950618

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Three-Dimensional Imaging
Fluorescence microscopy
Fluorescence Microscopy
Image segmentation
Chemical analysis
20 Citations (Scopus)

Two-photon intravital fluorescence lifetime imaging of the kidney reveals cell-type specific metabolic signatures

Hato, T., Winfree, S., Day, R., Sandoval, R. M., Molitoris, B., Yoder, M., Wiggins, R. C., Zheng, Y., Dunn, K. & Dagher, P., Aug 1 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2420-2430 11 p.

Research output: Contribution to journalArticle

Optical Imaging
Photons
Microscopy
Kidney
Metabolome
4 Citations (Scopus)

Using quantitative intravital multiphoton microscopy to dissect hepatic transport in rats

Dunn, K. & Ryan, J. C., Feb 1 2017, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

Liver
Rats
Microscopic examination
Solute transport
Fluorescence microscopy
2016
10 Citations (Scopus)

A simple approach for measuring FRET in fluorescent biosensors using two-photon microscopy

Day, R., Tao, W. & Dunn, K., Nov 1 2016, In : Nature Protocols. 11, 11, p. 2066-2080 15 p.

Research output: Contribution to journalArticle

Energy Transfer
Biosensing Techniques
Photons
Biosensors
Energy transfer

Four Dimensional Image Registration for Intravital Microscopy

Fu, C., Gadgil, N., Tahboub, K. K., Salama, P., Dunn, K. & Delp, E. J., Dec 16 2016, Proceedings - 29th IEEE Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2016. IEEE Computer Society, p. 1390-1398 9 p. 7789665

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Image registration
Tissue
Fluorescence microscopy
Splines
Animals
2 Citations (Scopus)

Gene targets of mouse miR-709: Regulation of distinct pools

Surendran, S., Jideonwo, V. N., Merchun, C., Ahn, M., Murray, J., Ryan, J., Dunn, K., Kota, J. & Morral, N., Jan 8 2016, In : Scientific Reports. 6, 18958.

Research output: Contribution to journalArticle

MicroRNAs
Cytoskeleton
Genes
Hepatocytes
Gene Pool
3 Citations (Scopus)

Jelly filling segmentation of fluorescence microscopy images containing incomplete labeling

Gadgil, N. J., Salama, P., Dunn, K. & Delp, E. J., Jun 15 2016, 2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Proceedings. IEEE Computer Society, Vol. 2016-June. p. 531-535 5 p. 7493324

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Fluorescence Microscopy
Labeling
Rats
Luminance
9 Citations (Scopus)

Nuclei segmentation of fluorescence microscopy images based on midpoint analysis and marked point process

Gadgil, N. J., Salama, P., Dunn, K. & Delp, E. J., Apr 25 2016, 2016 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2016 - Proceedings. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-April. p. 37-40 4 p. 7459169

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Image analysis
Luminance
Microscopes
Tissue
2015
10 Citations (Scopus)

A practical method for monitoring FRET-based biosensors in living animals using two-photon microscopy

Tao, W., Rubart-von der Lohe, M., Ryan, J., Xiao, X., Qiao, C., Hato, T., Davidson, M. W., Dunn, K. & Day, R., 2015, In : American Journal of Physiology - Cell Physiology. 309, 11, p. C724-C735

Research output: Contribution to journalArticle

Energy Transfer
Biosensing Techniques
Photons
Microscopy
Cyclic AMP-Dependent Protein Kinases
5 Citations (Scopus)

Boundary fitting based segmentation of fluorescence microscopy images

Lee, S., Salama, P., Dunn, K. & Delp, E. J., 2015, Proceedings of SPIE - The International Society for Optical Engineering. SPIE, Vol. 9408. 940805

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence Microscopy
Fluorescence microscopy
Microscopic examination
Segmentation
microscopy

Correction: RhoB-dependent modulation of early endocytic traffic in Madin-Darby canine kidney cells (Journal of Biological Chemistry (2004))

Rojas, R., Ruiz, W. G., Wang, E., Kinlough, C. L., Poland, P. A., Hughey, R. P., Dunn, K. & Apodaca, G., Aug 7 2015, In : Journal of Biological Chemistry. 290, 32, p. 19542 1 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
2014
35 Citations (Scopus)

Diversity of two forms of DNA methylation in the brain

Chen, Y., Damayanti, N. P., Irudayaraj, J., Dunn, K. & Zhou, F., 2014, In : Frontiers in Genetics. 5, MAR, Article 46.

Research output: Contribution to journalArticle

5-Methylcytosine
DNA Methylation
Brain
Chromatin
Neural Stem Cells
13 Citations (Scopus)
Fluorescein
Chronic Renal Insufficiency
Liver
Hepatocytes
Nephrectomy
2013
1 Citation (Scopus)

High resolution 4-dimension imaging of metanephric embryonic kidney morphogenesis

Clendenon, S. G., Ward, H. H., Dunn, K. & Bacallao, R., Apr 2013, In : Kidney International. 83, 4, p. 757-761 5 p.

Research output: Contribution to journalArticle

Organ Culture Techniques
Morphogenesis
Kidney
Multiphoton Fluorescence Microscopy
Three-Dimensional Imaging
45 Citations (Scopus)

Statistical tests for measures of colocalization in biological microscopy

Mcdonald, J. H. & Dunn, K., Dec 2013, In : Journal of Microscopy. 252, 3, p. 295-302 8 p.

Research output: Contribution to journalArticle

Microscopy
Students
Statistical Data Interpretation
Spatial Analysis
Random Allocation
11 Citations (Scopus)

Three dimensional segmentation of fluorescence microscopy images using active surfaces

Lorenz, K. S., Salama, P., Dunn, K. & Delp, E. J., 2013, 2013 IEEE International Conference on Image Processing, ICIP 2013 - Proceedings. p. 1153-1157 5 p. 6738238

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Tissue
Optical microscopy
Rats
Microscopic examination
2012
4 Citations (Scopus)

A multi-resolution approach to non-rigid registration of microscopy images

Lorenz, K. S., Salama, P., Dunn, K. & Delp, E. J., 2012, Proceedings - International Symposium on Biomedical Imaging. p. 198-201 4 p. 6235518

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Image registration
Artifacts
Microscopy
Microscopic examination
Lung
9 Citations (Scopus)

Digital correction of motion artefacts in microscopy image sequences collected from living animals using rigid and nonrigid registration

Lorenz, K. S., Salama, P., Dunn, K. & Delp, E. J., Feb 2012, In : Journal of Microscopy. 245, 2, p. 148-160 13 p.

Research output: Contribution to journalArticle

Artifacts
Microscopy
Salivary Glands
Rodentia
Kidney
19 Citations (Scopus)

Effects of IFN-γ on intracellular trafficking and activity of macrophage NADPH oxidase flavocytochrome b558

Casbon, A. J., Long, M. E., Dunn, K., Allen, L. A. H. & Dinauer, M. C., Oct 2012, In : Journal of Leukocyte Biology. 92, 4, p. 869-882 14 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Macrophages
Intracellular Membranes
Endosomes
Phagocytes

Functional studies in living animals using multiphoton microscopy

Dunn, K. & Sutton, T., 2012, In : ILAR Journal. 53, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

Microscopy
microscopy
Physiology
Microscopic examination
Animals
11 Citations (Scopus)
Microscopy
Microscopic examination
Animals
Kidney
Fluorescent Dyes
2011
604 Citations (Scopus)

A practical guide to evaluating colocalization in biological microscopy

Dunn, K., Kamocka, M. & McDonald, J. H., Apr 2011, In : American Journal of Physiology - Cell Physiology. 300, 4

Research output: Contribution to journalArticle

Fluorescence Microscopy
Microscopy
Cell Biology
Biomedical Research
Software
9 Citations (Scopus)

Deep tissue fluorescent imaging in scattering specimens using confocal microscopy

Clendenon, S. G., Young, P. A., Ferkowicz, M., Phillips, C. & Dunn, K., Aug 2011, In : Microscopy and Microanalysis. 17, 4, p. 614-617 4 p.

Research output: Contribution to journalArticle

clearing
Confocal microscopy
Scattering
Tissue
microscopy
71 Citations (Scopus)

Endotoxin uptake by S1 proximal tubular segment causes oxidative stress in the downstream S2 segment

Kalakeche, R., Hato, T., Rhodes, G., Dunn, K., Ashkar (El-Achkar), T., Plotkin, Z., Sandoval, R. M. & Dagher, P., 2011, In : Journal of the American Society of Nephrology. 22, 8, p. 1505-1516 12 p.

Research output: Contribution to journalArticle

Endotoxins
Oxidative Stress
Sirtuin 1
Acute Kidney Injury
Sepsis
1 Citation (Scopus)

Non-rigid registration of multiphoton microscopy images using B-splines

Lorenz, K. S., Salama, P., Dunn, K. & Delp, E. J., 2011, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7962. 796221

Research output: Chapter in Book/Report/Conference proceedingConference contribution

splines
Splines
Microscopy
Microscopic examination
microscopy
11 Citations (Scopus)

The effects of refractive index heterogeneity within kidney tissue on multiphoton fluorescence excitation microscopy

Young, P. A., Clendenon, S. G., Byars, J. M. & Dunn, K., May 2011, In : Journal of Microscopy. 242, 2, p. 148-156 9 p.

Research output: Contribution to journalArticle

Multiphoton Fluorescence Microscopy
Refractometry
Kidney
Fluorescence
13 Citations (Scopus)

The effects of spherical aberration on multiphoton fluorescence excitation microscopy

Young, P. A., Clendenon, S. G., Byars, J. M., Decca, R. S. & Dunn, K., May 2011, In : Journal of Microscopy. 242, 2, p. 157-165 9 p.

Research output: Contribution to journalArticle

Multiphoton Fluorescence Microscopy
Refractometry
Fluorescence
Photobleaching
Immersion
35 Citations (Scopus)

Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact

Presson, R., Brown, M. B., Fisher, A. J., Sandoval, R. M., Dunn, K., Lorenz, K. S., Delp, E. J., Salama, P., Molitoris, B. & Petrache, I., Jul 2011, In : American Journal of Pathology. 179, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Photons
Artifacts
Thorax
Microscopy
Leukocytes