Kenneth Dunn

  • 4900 Citations
  • 36 h-Index
1988 …2020

Research output per year

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Publications

2020

Mitochondrial depolarization and repolarization in the early stages of acetaminophen hepatotoxicity in mice

Dunn, K. W., Martinez, M. M., Wang, Z., Mang, H. E., Clendenon, S. G., Sluka, J. P., Glazier, J. A. & Klaunig, J. E., Jun 2020, In : Toxicology. 439, 152464.

Research output: Contribution to journalArticle

Open Access

PIE-FLIM Measurements of Two Different FRET-Based Biosensor Activities in the Same Living Cells

Reissaus, C. A., Day, K. H., Mirmira, R. G., Dunn, K. W., Pavalko, F. M. & Day, R. N., Apr 21 2020, In : Biophysical journal. 118, 8, p. 1820-1829 10 p.

Research output: Contribution to journalArticle

Three Dimensional Nuclei Segmentation and Classification of Fluorescence Microscopy Images

Han, S., Lee, S., Chen, A., Yang, C., Salama, P., Dunn, K. W. & Delp, E. J., Apr 2020, ISBI 2020 - 2020 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 526-530 5 p. 9098560. (Proceedings - International Symposium on Biomedical Imaging; vol. 2020-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2019

A simple automated method for continuous fieldwise measurement of microvascular hemodynamics

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A. J., Klaunig, J. E., Glazier, J. A. & Dunn, K. W., May 2019, In : Microvascular Research. 123, p. 7-13 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Automatic segmentation of intravital fluorescence microscopy images by K-means clustering of FLIM phasors

Zhang, Y., Hato, T., Dagher, P. C., Nichols, E. L., Smith, C. J., Dunn, K. W. & Howard, S. S., Aug 15 2019, In : Optics Letters. 44, 16, p. 3928-3931 4 p.

Research output: Contribution to journalArticle

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

Reissaus, C. A., Piñeros, A. R., Twigg, A. N., Orr, K. S., Conteh, A. M., Martinez, M. M., Kamocka, M. M., Day, R. N., Tersey, S. A., Mirmira, R. G., Dunn, K. W. & Linnemann, A. K., Dec 1 2019, In : Scientific reports. 9, 1, 8449.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Center-extraction-based three dimensional nuclei instance segmentation of fluorescence microscopy images

Ho, D. J., Han, S., Fu, C., Salama, P., Dunn, K. W. & Delp, E. J., May 2019, 2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 8834516. (2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

DeepSynth: Three-dimensional nuclear segmentation of biological images using neural networks trained with synthetic data

Dunn, K. W., Fu, C., Ho, D. J., Lee, S., Han, S., Salama, P. & Delp, E. J., Dec 1 2019, In : Scientific reports. 9, 1, 18295.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Nuclei counting in microscopy images with three dimensional generative adversarial networks

Han, S., Lee, S., Fu, C., Salama, P., Dunn, K. W. & Delp, E. J., Jan 1 2019, Medical Imaging 2019: Image Processing. Angelini, E. D., Angelini, E. D., Angelini, E. D. & Landman, B. A. (eds.). SPIE, 109492Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10949).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Quantitative Kinetic Models from Intravital Microscopy: A Case Study Using Hepatic Transport

Tavakoli, M., Tsekouras, K., Day, R., Dunn, K. W. & Pressé, S., May 19 2019, In : Journal of Physical Chemistry B. 123, 34, p. 7302-7312 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Spatial temporal analysis of fieldwise flow in microvasculature

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A., Klaunig, J. E., Glazier, J. A. & Dunn, K. W., Nov 2019, In : Journal of Visualized Experiments. 2019, 153, e60493.

Research output: Contribution to journalArticle

Three dimensional blind image deconvolution for fluorescence microscopy using generative adversarial networks

Lee, S., Han, S., Salama, P., Dunn, K. W. & Delp, E. J., Apr 2019, ISBI 2019 - 2019 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 538-542 5 p. 8759250. (Proceedings - International Symposium on Biomedical Imaging; vol. 2019-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
2018

Intravital multiphoton microscopy with fluorescent bile salts in rats as an in vivo biomarker for hepatobiliary transport inhibition

Ryan, J., Morgan, R. E., Chen, Y., Volak, L. P., Dunn, R. T. & Dunn, K. W., May 2018, In : Drug Metabolism and Disposition. 46, 5, p. 704-718 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Kinetic analysis of vasculogenesis quantifies dynamics of vasculogenesis and angiogenesis in vitro

Varberg, K. M., Winfree, S., Dunn, K. W. & Haneline, L. S., Jan 31 2018, In : Journal of Visualized Experiments. 2018, 131, e57044.

Research output: Contribution to journalArticle

3 Scopus citations

Live-Animal Imaging of Renal Function by Multiphoton Microscopy

Dunn, K. W., Sutton, T. A. & Sandoval, R. M., Jan 1 2018, In : Current Protocols in Cytometry. 83, 1, p. 12.9.1-12.9.25

Research output: Contribution to journalArticle

5 Scopus citations

Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models

Fu, X., Sluka, J. P., Clendenon, S. G., Dunn, K. W., Wang, Z., Klaunig, J. E. & Glazier, J. A., Sep 2018, In : PloS one. 13, 9, e0198060.

Research output: Contribution to journalArticle

5 Scopus citations

Nuclei detection and segmentation of fluorescence microscopy images using three dimensional convolutional neural networks

Ho, D. J., Fu, C., Salama, P., Dunn, K. W. & Delp, E. J., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, p. 418-422 5 p. (Proceedings - International Symposium on Biomedical Imaging; vol. 2018-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Quantitative large-scale three-dimensional imaging of human kidney biopsies: A bridge to precision medicine in kidney disease

Winfree, S., Dagher, P. C., Dunn, K. W., Eadon, M. T., Ferkowicz, M., Barwinska, D., Kelly, K. J., Sutton, T. A. & El-Achkar, T. M., Sep 1 2018, In : Nephron. 140, 2, p. 134-139 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

Segmentation of biological images containing multitarget labeling using the jelly filling framework

Gadgil, N. J., Salama, P., Dunn, K. W. & Delp, E. J., Oct 1 2018, In : Journal of Medical Imaging. 5, 4, 044006.

Research output: Contribution to journalArticle

Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease

Swallow, E. A., Aref, M. W., Chen, N., Byiringiro, I., Hammond, M. A., McCarthy, B. P., Territo, P. R., Kamocka, M. M., Winfree, S., Dunn, K. W., Moe, S. M. & Allen, M. R., Sep 1 2018, In : Osteoporosis International. 29, 9, p. 2139-2146 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Three dimensional fluorescence microscopy image synthesis and segmentation

Fu, C., Lee, S., Ho, D. J., Han, S., Salama, P., Dunn, K. & Delp, E. J., Dec 13 2018, Proceedings - 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2018. IEEE Computer Society, Vol. 2018-June. p. 2302-2310 9 p. 8575470

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations
5 Scopus citations
2017

Boundary segmentation for fluorescence microscopy using steerable filters

Ho, D. J., Salama, P., Dunn, K. W. & Delp, E. J., Jan 1 2017, Medical Imaging 2017: Image Processing. Angelini, E. D., Styner, M. A. & Angelini, E. D. (eds.). SPIE, 101330E. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10133).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Imaging cell biology and physiology in vivo using intravital microscopy

Dunn, K. & Day, R., Sep 1 2017, In : Methods. 128, p. 1-2 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Kinetic analyses of vasculogenesis inform mechanistic studies

Varberg, K. M., Winfree, S., Chu, C., Tu, W., Blue, E. K., Gohn, C. R., Dunn, K. W. & Haneline, L. S., Apr 7 2017, In : American Journal of Physiology - Cell Physiology. 312, 4, p. C446-C458

Research output: Contribution to journalArticle

2 Scopus citations

Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications

Winfree, S., Ferkowicz, M. J., Dagher, P. C., Kelly, K. J., Eadon, M. T., Sutton, T. A., Markel, T. A., Yoder, M. C., Dunn, K. W. & El-Achkar, T. M., Nov 2017, In : Translational Research. 189, p. 1-12 12 p.

Research output: Contribution to journalReview article

6 Scopus citations

Nuclei segmentation of fluorescence microscopy images using convolutional neural networks

Fu, C., Ho, D. J., Han, S., Salama, P., Dunn, K. & Delp, E. J., Jun 15 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging, ISBI 2017. IEEE Computer Society, p. 704-708 5 p. 7950617

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations

Nuclei Segmentation of Fluorescence Microscopy Images Using Three Dimensional Convolutional Neural Networks

Ho, D. J., Fu, C., Salama, P., Dunn, K. & Delp, E. J., Aug 22 2017, Proceedings - 30th IEEE Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2017. IEEE Computer Society, Vol. 2017-July. p. 834-842 9 p. 8014850

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Quantitative three-dimensional tissue cytometry to study kidney tissue and resident immune cells

Winfree, S., Khan, S., Micanovic, R., Eadon, M., Kelly, K., Sutton, T., Phillips, C., Dunn, K. & Ashkar (El-Achkar), T., Jul 1 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2108-2118 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Segmentation of fluorescence microscopy images using three dimensional active contours with inhomogeneity correction

Lee, S., Salama, P., Dunn, K. W. & Delp, E. J., Jun 15 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging, ISBI 2017. IEEE Computer Society, p. 709-713 5 p. 7950618. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Two-photon intravital fluorescence lifetime imaging of the kidney reveals cell-type specific metabolic signatures

Hato, T., Winfree, S., Day, R., Sandoval, R. M., Molitoris, B. A., Yoder, M. C., Wiggins, R. C., Zheng, Y., Dunn, K. W. & Dagher, P. C., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2420-2430 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Using quantitative intravital multiphoton microscopy to dissect hepatic transport in rats

Dunn, K. W. & Ryan, J. C., Sep 1 2017, In : Methods. 128, p. 40-51 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

A simple approach for measuring FRET in fluorescent biosensors using two-photon microscopy

Day, R. N., Tao, W. & Dunn, K. W., Nov 1 2016, In : Nature protocols. 11, 11, p. 2066-2080 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Four Dimensional Image Registration for Intravital Microscopy

Fu, C., Gadgil, N., Tahboub, K. K., Salama, P., Dunn, K. & Delp, E. J., Dec 16 2016, Proceedings - 29th IEEE Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2016. IEEE Computer Society, p. 1390-1398 9 p. 7789665

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gene targets of mouse miR-709: Regulation of distinct pools

Surendran, S., Jideonwo, V. N., Merchun, C., Ahn, M., Murray, J., Ryan, J., Dunn, K. W., Kota, J. & Morral, N., Jan 8 2016, In : Scientific reports. 6, 18958.

Research output: Contribution to journalArticle

2 Scopus citations

Jelly filling segmentation of fluorescence microscopy images containing incomplete labeling

Gadgil, N. J., Salama, P., Dunn, K. W. & Delp, E. J., Jun 15 2016, 2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Proceedings. IEEE Computer Society, p. 531-535 5 p. 7493324. (Proceedings - International Symposium on Biomedical Imaging; vol. 2016-June).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Nuclei segmentation of fluorescence microscopy images based on midpoint analysis and marked point process

Gadgil, N. J., Salama, P., Dunn, K. & Delp, E. J., Apr 25 2016, 2016 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2016 - Proceedings. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-April. p. 37-40 4 p. 7459169

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations
2015

A practical method for monitoring FRET-based biosensors in living animals using two-photon microscopy

Tao, W., Rubart, M., Ryan, J., Xiao, X., Qiao, C., Hato, T., Davidson, M. W., Dunn, K. W. & Day, R. N., Jan 1 2015, In : American Journal of Physiology - Cell Physiology. 309, 11, p. C724-C735

Research output: Contribution to journalArticle

13 Scopus citations

Boundary fitting based segmentation of fluorescence microscopy images

Lee, S., Salama, P., Dunn, K. W. & Delp, E. J., Jan 1 2015, Proceedings of SPIE-IS and T Electronic Imaging - Imaging and Multimedia Analytics in a Web and Mobile World 2015. Allebach, J. P., Fan, Z. & Lin, Q. (eds.). SPIE, 940805. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 9408).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Correction: RhoB-dependent modulation of early endocytic traffic in Madin-Darby canine kidney cells (Journal of Biological Chemistry (2004))

Rojas, R., Ruiz, W. G., Wang, E., Kinlough, C. L., Poland, P. A., Hughey, R. P., Dunn, K. W. & Apodaca, G., Aug 7 2015, In : Journal of Biological Chemistry. 290, 32, 1 p.

Research output: Contribution to journalComment/debate

2014

Diversity of two forms of DNA methylation in the brain

Chen, Y., Damayanti, N. P., Irudayaraj, J., Dunn, K. & Zhou, F. C., Jan 1 2014, In : Frontiers in Genetics. 5, MAR, Article 46.

Research output: Contribution to journalArticle

43 Scopus citations
16 Scopus citations
2013

High resolution 4-dimension imaging of metanephric embryonic kidney morphogenesis

Clendenon, S. G., Ward, H. H., Dunn, K. W. & Bacallao, R., Apr 2013, In : Kidney international. 83, 4, p. 757-761 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Statistical tests for measures of colocalization in biological microscopy

Mcdonald, J. H. & Dunn, K. W., Dec 1 2013, In : Journal of Microscopy. 252, 3, p. 295-302 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Three dimensional segmentation of fluorescence microscopy images using active surfaces

Lorenz, K. S., Salama, P., Dunn, K. W. & Delp, E. J., Dec 1 2013, 2013 IEEE International Conference on Image Processing, ICIP 2013 - Proceedings. p. 1153-1157 5 p. 6738238. (2013 IEEE International Conference on Image Processing, ICIP 2013 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations
2012

A multi-resolution approach to non-rigid registration of microscopy images

Lorenz, K. S., Salama, P., Dunn, K. W. & Delp, E. J., Aug 15 2012, 2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Proceedings. p. 198-201 4 p. 6235518. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Digital correction of motion artefacts in microscopy image sequences collected from living animals using rigid and nonrigid registration

Lorenz, K. S., Salama, P., Dunn, K. W. & Delp, E. J., Feb 1 2012, In : Journal of Microscopy. 245, 2, p. 148-160 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effects of IFN-γ on intracellular trafficking and activity of macrophage NADPH oxidase flavocytochrome b558

Casbon, A. J., Long, M. E., Dunn, K. W., Allen, L. A. H. & Dinauer, M. C., Oct 1 2012, In : Journal of Leukocyte Biology. 92, 4, p. 869-882 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Functional studies in living animals using multiphoton microscopy

Dunn, K. W. & Sutton, T. A., Sep 11 2012, In : ILAR Journal. 53, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

Live-animal imaging of renal function by multiphoton Microscopy

Dunn, K. W., Sutton, T. A. & Sandoval, R. M., Dec 1 2012, In : Current Protocols in Cytometry. SUPPL.62, p. 12.9

Research output: Contribution to journalArticle

12 Scopus citations