Khalid Mohammad

  • 3584 Citations
  • 25 h-Index
19992019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1999 2019

  • 3584 Citations
  • 25 h-Index
  • 66 Article
  • 1 Chapter
  • 1 Letter
  • 1 Short survey
Filter
Article
2019
2 Citations (Scopus)

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

Saito, H., Gasser, A., Bolamperti, S., Maeda, M., Matthies, L., Jähn, K., Long, C. L., Schlüter, H., Kwiatkowski, M., Saini, V., Pajevic, P. D., Bellido, T., van Wijnen, A. J., Mohammad, K., Guise, T., Taipaleenmäki, H. & Hesse, E., Dec 1 2019, In : Nature Communications. 10, 1, 1354.

Research output: Contribution to journalArticle

Open Access
hormones
Bone Remodeling
Parathyroid Hormone
bones
osteogenesis
2018

A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone

Waning, D. L., Guise, T. & Mohammad, K., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Bone Neoplasms
Connexins
Bone and Bones
Neoplasm Metastasis
Neoplasms
1 Citation (Scopus)

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

Petrusca, D., Toscani, D., Wang, F. M., Park, C., Crean, C. D., Anderson, J. L., Marino, S., Mohammad, K., Zhou, D., Silbermann, R., Sun, Q., Kurihara, N., Galson, D. L., Giuliani, N. & Roodman, G. D., Oct 4 2018, In : Journal of Hematology and Oncology. 11, 1, 123.

Research output: Contribution to journalArticle

Multiple Myeloma
Osteogenesis
Intercellular Signaling Peptides and Proteins
Survival
Growth
2017
11 Citations (Scopus)

Aromatase inhibitor-induced bone loss increases the progression of estrogen receptor-negative breast cancer in bone and exacerbates muscle weakness in vivo

Wright, L., Harhash, A. A., Kozlow, W. M., Waning, D. L., Regan, J., She, Y., John, S. K., Murthy, S., Niewolna, M., Marks, A. R., Mohammad, K. & Guise, T., 2017, In : Oncotarget. 8, 5, p. 8406-8419 14 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Aromatase Inhibitors
Muscle Weakness
Estrogen Receptors
Breast Neoplasms
13 Citations (Scopus)

Bone-induced expression of integrin b3 enables targeted nanotherapy of breast cancer metastases

Ross, M. H., Esser, A. K., Fox, G. C., Schmieder, A. H., Yang, X., Hu, G., Pan, D., Su, X., Xu, Y., Novack, D. V., Walsh, T., Colditz, G. A., Lukaszewicz, G. H., Cordell, E., Novack, J., Fitzpatrick, J. A. J., Waning, D. L., Mohammad, K., Guise, T., Lanza, G. M. & 1 others, Weilbaecher, K. N., Nov 15 2017, In : Cancer Research. 77, 22, p. 6299-6312 14 p.

Research output: Contribution to journalArticle

docetaxel
Integrins
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
12 Citations (Scopus)

Differential bone loss in mouse models of colon cancer cachexia

Bonetto, A., Kays, J. K., Parker, V. A., Matthews, R. R., Barreto, R., Puppa, M. J., Kang, K. S., Carson, J. A., Guise, T., Mohammad, K., Robling, A., Couch, M. E., Koniaris, L. & Zimmers, T., 2017, In : Frontiers in Physiology. 7, JAN, 679.

Research output: Contribution to journalArticle

Cachexia
Colonic Neoplasms
Bone and Bones
Muscles
Bone Density
6 Citations (Scopus)

Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

Juárez, P., Fournier, P. G. J., Mohammad, K., McKenna, R. C., Davis, H. W., Peng, X. H., Niewolna, M., Mauviel, A., Chirgwin, J. & Guise, T., Oct 17 2017, In : Oncotarget. 8, 49, p. 86447-86462 16 p.

Research output: Contribution to journalArticle

zoledronic acid
Bone Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones

Improved autologous cortical bone harvest and viability with 2Flute otologic burs

Roth, A. A., Tang, P. C., Ye, M. J., Mohammad, K. & Nelson, R., 2017, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Bone and Bones
Osteoblasts
Osteogenesis
Cortical Bone
Cell Count
12 Citations (Scopus)

Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells

Singh, P., Hoggatt, J., Kamocka, M., Mohammad, K., Saunders, M. R., Li, H., Speth, J., Carlesso, N., Guise, T. & Pelus, L., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4527-4540 14 p.

Research output: Contribution to journalArticle

Neuropeptide Y
Hematopoietic Stem Cells
Blood Vessels
Endothelial Cells
Hematopoietic Stem Cell Mobilization
16 Citations (Scopus)

Osteocyte-Intrinsic TGF-β Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling

Dole, N. S., Mazur, C. M., Acevedo, C., Lopez, J. P., Monteiro, D. A., Fowler, T. W., Gludovatz, B., Walsh, F., Regan, J., Messina, S., Evans, D. S., Lang, T. F., Zhang, B., Ritchie, R. O., Mohammad, K. & Alliston, T., Nov 28 2017, In : Cell Reports. 21, 9, p. 2585-2596 12 p.

Research output: Contribution to journalArticle

Osteocytes
Transforming Growth Factor beta
Bone
Bone and Bones
Quality Control
4 Citations (Scopus)

Osteolytic breast cancer causes skeletal muscle weakness in an immunocompetent syngeneic mouse model

Regan, J., Mikesell, C., Reiken, S., Xu, H., Marks, A. R., Mohammad, K., Guise, T. & Waning, D. L., Dec 19 2017, In : Frontiers in Endocrinology. 8, DEC, 358.

Research output: Contribution to journalArticle

Muscle Weakness
Bone Neoplasms
Skeletal Muscle
Ryanodine Receptor Calcium Release Channel
Cachexia
8 Citations (Scopus)

The P2Y2 nucleotide receptor is an inhibitor of vascular calcification

Qian, S., Regan, J., Shelton, M. T., Hoggatt, A., Mohammad, K., Herring, B. & Seye, C., Feb 1 2017, In : Atherosclerosis. 257, p. 38-46 9 p.

Research output: Contribution to journalArticle

Purinergic P2Y2 Receptors
Vascular Calcification
Nucleotides
Tunica Intima
Vascular Smooth Muscle
8 Citations (Scopus)

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

Trivedi, T., Zheng, Y., Fournier, P. G. J., Murthy, S., John, S., Schillo, S., Dunstan, C. R., Mohammad, K., Zhou, H., Seibel, M. J. & Guise, T., 2017, In : Oncotarget. 8, 16, p. 26687-26701 15 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Cytoplasm
Breast Neoplasms
Ligands
Growth
2016
64 Citations (Scopus)
Osteocytes
Tumor Microenvironment
Multiple Myeloma
Bone Marrow
Cell Proliferation
16 Citations (Scopus)

Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo

Teramachi, J., Silbermann, R., Yang, P., Zhao, W., Mohammad, K., Guo, J., Anderson, J. L., Zhou, D., Feng, R., Myint, K. Z., Maertz, N., Beumer, J. H., Eiseman, J. L., Windle, J. J., Xie, X. Q., Roodman, G. D. & Kurihara, N., Feb 1 2016, In : Leukemia. 30, 2, p. 390-398 9 p.

Research output: Contribution to journalArticle

Osteoclasts
Multiple Myeloma
Osteogenesis
Bone and Bones
Growth
4 Citations (Scopus)

Cell adhesion molecule CD166 drives malignant progression and osteolytic disease in multiple myeloma

Xu, L., Mohammad, K., Wu, H., Crean, C., Poteat, B., Cheng, Y., Cardoso, A. A., Machal, C., Hanenberg, H., Abonour, R., Kacena, M., Chirgwin, J., Suvannasankha, A. & Srour, E., Dec 1 2016, In : Cancer Research. 76, 23, p. 6901-6910 10 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Multiple Myeloma
Disease Progression
Bone Marrow Cells
Bone Marrow

Hypercalcemia of malignancy: A new twist on an old problem

Mohammad, K. & Guise, T., May 1 2016, In : Journal of Oncology Practice. 12, 5, p. 435-436 2 p.

Research output: Contribution to journalArticle

Hypercalcemia
Neoplasms
9 Citations (Scopus)

Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice

Zhang, P., Xing, C., Rhodes, S. D., He, Y., Deng, K., Li, Z., He, F., Zhu, C., Nguyen, L., Zhou, Y., Chen, S., Mohammad, K., Guise, T., Abdel-Wahab, O., Xu, M., Wang, Q. F. & Yang, F. C., Jan 26 2016, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone
Genes
Osteoblasts
Defects
15 Citations (Scopus)

Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease

Teramachi, J., Nagata, Y., Mohammad, K., Inagaki, Y., Ohata, Y., Guise, T., Michou, L., Brown, J. P., Windle, J. J., Kurihara, N. & Roodman, G. D., Mar 1 2016, In : Journal of Clinical Investigation. 126, 3, p. 1012-1022 11 p.

Research output: Contribution to journalArticle

Osteoclasts
Osteoblasts
Bone Resorption
Osteogenesis
Interleukin-6
2015
3 Citations (Scopus)

Dystrophic spinal deformities in a neurofibromatosis type 1 murine model

Rhodes, S. D., Zhang, W., Yang, D., Yang, H., Chen, S., Wu, X., Li, X., Yang, X., Mohammad, K., Guise, T., Bergner, A. L., Stevenson, D. A. & Yang, F. C., Mar 18 2015, In : PLoS One. 10, 3, e0119093.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Fusion reactions
animal models
intervertebral disks
Intervertebral Disc
105 Citations (Scopus)

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

Waning, D. L., Mohammad, K., Reiken, S., Xie, W., Andersson, D. C., John, S., Chiechi, A., Wright, L., Umanskaya, A., Niewolna, M., Trivedi, T., Charkhzarrin, S., Khatiwada, P., Wronska, A., Haynes, A., Benassi, M. S., Witzmann, F., Zhen, G., Wang, X., Cao, X. & 3 others, Roodman, G. D., Marks, A. R. & Guise, T., Nov 1 2015, In : Nature Medicine. 21, 11, p. 1262-1271 10 p.

Research output: Contribution to journalArticle

Muscle Weakness
Transforming Growth Factors
Ryanodine Receptor Calcium Release Channel
Muscle
Bone
2 Citations (Scopus)

Nf1 haploinsufficiency alters myeloid lineage commitment and function, leading to deranged skeletal homeostasis

Rhodes, S. D., Yang, H., Dong, R., Menon, K., He, Y., Li, Z., Chen, S., Staser, K. W., Jiang, L., Wu, X., Yang, X., Peng, X., Mohammad, K., Guise, T., Xu, M. & Yang, F. C., Oct 1 2015, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 10, p. 1840-1851 12 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Neurofibromatosis 1
Osteoclasts
Homeostasis
Osteogenesis
28 Citations (Scopus)

Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

Wu, C., Rankin1, E. B., Castellini, L., Fernandez-Alcudia, J., Lagory, E. L., Andersen, R., Rhodes, S. D., Wilson, T. L. S., Mohammad, K., Castillo, A. B., Guise, T., Schipani, E. & Giaccia, A. J., 2015, In : Genes and Development. 29, 8, p. 817-831 15 p.

Research output: Contribution to journalArticle

Osteoprotegerin
Homeostasis
Oxygen
Bone and Bones
Prolyl Hydroxylases
26 Citations (Scopus)

Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model

Wright, L., Buijs, J. T., Kim, H. S., Coats, L. E., Scheidler, A. M., John, S. K., She, Y., Murthy, S., Ma, N., Chin-Sinex, H. J., Bellido, T., Bateman, T. A., Mendonca, M., Mohammad, K. & Guise, T., Jul 1 2015, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 7, p. 1268-1279 12 p.

Research output: Contribution to journalArticle

Extremities
Bone and Bones
Osteoblasts
Osteocytes
Hindlimb
2 Citations (Scopus)

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; The effect of pharmacological targeting TGFβ receptor i kinase

Buijs, J. T., Matula, K. M., Cheung, H., Kruithof-De Julio, M., Van Der Mark, M. H., Snoeks, T. J., Cohen, R., Corver, W. E., Mohammad, K., Jonkers, J., Guise, T. & Van Der Pluijm, G., Apr 1 2015, In : Journal of Pathology. 235, 5, p. 745-759 15 p.

Research output: Contribution to journalArticle

Lobular Carcinoma
Phosphotransferases
Pharmacology
Breast Neoplasms
Neoplasm Metastasis
86 Citations (Scopus)

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

Fournier, P. G. J., Juárez, P., Jiang, G., Clines, G. A., Niewolna, M., Kim, H. S., Walton, H. W., Peng, X. H., Liu, Y., Mohammad, K., Wells, C., Chirgwin, J. & Guise, T., Jun 8 2015, In : Cancer Cell. 27, 6, p. 809-821 13 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Prostatic Neoplasms
Bone Neoplasms
Neoplasm Metastasis
Gene Expression
11 Citations (Scopus)

Tip110 regulates the cross talk between p53 and hypoxia-inducible factor 1α under hypoxia and promotes survival of cancer cells

Timani, K. A., Liu, Y., Fan, Y., Mohammad, K. & He, J. J., 2015, In : Molecular and Cellular Biology. 35, 13, p. 2254-2264 11 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Cell Survival
Neoplasms
Physiological Phenomena
Protein Stability
2014
18 Citations (Scopus)

Generation of the first autosomal dominant osteopetrosis type II (ADO2) disease models

Alam, I., Gray, A. K., Chu, K., Ichikawa, S., Mohammad, K., Capannolo, M., Capulli, M., Maurizi, A., Muraca, M., Teti, A., Econs, M. & Del Fattore, A., 2014, In : Bone. 59, p. 66-75 10 p.

Research output: Contribution to journalArticle

Osteopetrosis
Osteoclasts
Missense Mutation
Genes
Modifier Genes
17 Citations (Scopus)

Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis

Siclari, V. A., Mohammad, K., Tompkins, D. R., Davis, H., McKenna, C. R., Peng, X., Wessner, L. L., Niewolna, M., Guise, T., Suvannasankha, A. & Chirgwin, J., Dec 2 2014, In : Breast Cancer Research. 16, 1, 458.

Research output: Contribution to journalArticle

Adrenomedullin
Bone Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
2013
10 Citations (Scopus)

Cancer-Associated Osteoclast Differentiation Takes a Good Look in the miR(NA)ror

Waning, D., Mohammad, K. & Guise, T., Oct 14 2013, In : Cancer Cell. 24, 4, p. 407-409 3 p.

Research output: Contribution to journalArticle

Osteoclasts
Neoplasm Metastasis
MicroRNAs
Bone and Bones
Bone Neoplasms
16 Citations (Scopus)

Curcuminoids block TGF-β signaling in human breast cancer cells and limit osteolysis in a murine model of breast cancer bone metastasis

Wright, L., Frye, J. B., Lukefahr, A. L., Timmermann, B. N., Mohammad, K., Guise, T. & Funk, J. L., Mar 22 2013, In : Journal of Natural Products. 76, 3, p. 316-321 6 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Osteolysis
Transforming Growth Factors
Bone
Cells
77 Citations (Scopus)

Differential stem-and progenitor-cell trafficking by prostaglandin e 2

Hoggatt, J., Mohammad, K., Singh, P., Hoggatt, A. F., Chitteti, B. R., Speth, J. M., Hu, P., Poteat, B. A., Stilger, K. N., Ferraro, F., Silberstein, L., Wong, F. K., Farag, S., Czader, M., Milne, G. L., Breyer, R. M., Serezani, C. H., Scadden, D. T., Guise, T., Srour, E. & 1 others, Pelus, L., Mar 21 2013, In : Nature. 495, 7441, p. 365-369 5 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Prostaglandins
Stem Cells
Prostaglandins E
Receptors, Prostaglandin E, EP2 Subtype
25 Citations (Scopus)

Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model

Rhodes, S. D., Wu, X., He, Y., Chen, S., Yang, H., Staser, K. W., Wang, J., Zhang, P., Jiang, C., Yokota, H., Dong, R., Peng, X., Yang, X., Murthy, S., Azhar, M., Mohammad, K., Xu, M., Guise, T. & Yang, F. C., Dec 2013, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 28, 12, p. 2476-2489 14 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Transforming Growth Factors
Transforming Growth Factor beta
Osteoblasts
Pseudarthrosis
11 Citations (Scopus)

Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness.

Hoggatt, J., Mohammad, K., Singh, P. & Pelus, L., Oct 24 2013, In : Blood. 122, 17, p. 2997-3000 4 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Dinoprostone
Stem Cells
Transplantation
44 Citations (Scopus)

RANKL/RANK/MMP-1 Molecular Triad Contributes to the Metastatic Phenotype of Breast and Prostate Cancer Cells In Vitro

Casimiro, S., Mohammad, K., Pires, R., Tato-Costa, J., Alho, I., Teixeira, R., Carvalho, A., Ribeiro, S., Lipton, A., Guise, T. & Costa, L., May 16 2013, In : PLoS One. 8, 5, e63153.

Research output: Contribution to journalArticle

interstitial collagenase
prostatic neoplasms
Matrix Metalloproteinases
breast neoplasms
Prostatic Neoplasms
2012
14 Citations (Scopus)

c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions

He, Y., Rhodes, S. D., Chen, S., Wu, X., Yuan, J., Yang, X., Jiang, L., Li, X., Takahashi, N., Xu, M., Mohammad, K., Guise, T. & Yang, F. C., Nov 7 2012, In : PLoS One. 7, 11, e46900.

Research output: Contribution to journalArticle

osteoclasts
Neurofibromatosis 1
Osteoclasts
macrophage colony-stimulating factor
Macrophage Colony-Stimulating Factor
23 Citations (Scopus)

Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat pad

Nickerson, N. K., Mohammad, K., Gilmore, J. L., Crismore, E., Bruzzaniti, A., Guise, T. & Foley, J., Jan 19 2012, In : PLoS One. 7, 1, e30255.

Research output: Contribution to journalArticle

Bone Development
Epidermal Growth Factor Receptor
breast neoplasms
breasts
Adipose Tissue
25 Citations (Scopus)

Halofuginone inhibits the establishment and progression of melanoma bone metastases

Juaŕez, P., Mohammad, K., Yin, J. J., Fournier, P. G. J., McKenna, R. C., Davis, H. W., Peng, X. H., Niewolna, M., Javelaud, D., Chirgwin, J., Mauviel, A. & Guise, T., Dec 1 2012, In : Cancer Research. 72, 23, p. 6247-6256 10 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
Bone and Bones
halofuginone
Interleukin-11
20 Citations (Scopus)

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

Pollari, S., Käkönen, R. S., Mohammad, K., Rissanen, J. P., Halleen, J. M., Wärri, A., Nissinen, L., Pihlavisto, M., Marjamäki, A., Perälä, M., Guise, T., Kallioniemi, O. & Käkönen, S. M., May 2012, In : Molecular Cancer Research. 10, 5, p. 597-604 8 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Polysaccharides
Heparin
Interleukin-11
Breast Neoplasms
121 Citations (Scopus)

Tissue transglutaminase links TGF-Β, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer

Cao, L., Shao, M., Schilder, J., Guise, T., Mohammad, K. & Matei, D., May 17 2012, In : Oncogene. 31, 20, p. 2521-2534 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Transforming Growth Factors
Ovarian Neoplasms
Stem Cells
Phenotype
2011

Correction: TGF-β-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases (Cancer Research (2011) 71, (175-184))

Mohammad, K., Javelaud, D., Fournier, P. G. J., Niewolna, M., McKenna, C. R., Peng, X. H., Duong, V., Dunn, L. K., Mauviel, A. & Guise, T., Mar 1 2011, In : Cancer Research. 71, 5, p. 2023 1 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Transforming Growth Factor beta
Melanoma
Phosphotransferases
Neoplasm Metastasis
22 Citations (Scopus)

Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor

Clines, G. A., Mohammad, K., Grunda, J. M., Clines, K. L., Niewolna, M., McKenna, C. R., McKibbin, C. R., Yanagisawa, M., Suva, L. J., Chirgwin, J. & Guise, T., Oct 2011, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 26, 10, p. 2523-2536 14 p.

Research output: Contribution to journalArticle

Endothelin A Receptors
Osteoblasts
Osteogenesis
Endothelin-1
Bone and Bones
13 Citations (Scopus)

Tetra-methoxystilbene modulates ductal growth of the developing murine mammary gland

Kim, T., Park, H., Yue, W., Wang, J. P., Atkins, K. A., Zhang, Z., Rogan, E. G., Cavalieri, E. L., Mohammad, K., Kim, S., Santen, R. J. & Aiyar, S. E., Apr 2011, In : Breast Cancer Research and Treatment. 126, 3, p. 779-789 11 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Breast
Cytochrome P-450 Enzyme System
Growth
Breast Neoplasms
113 Citations (Scopus)

TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

Javelaud, D., Alexaki, V. I., Dennler, S., Mohammad, K., Guise, T. & Mauviel, A., Sep 1 2011, In : Cancer Research. 71, 17, p. 5606-5610 5 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Neoplasms
Embryonic Development
Cell Differentiation
Transcription Factors
135 Citations (Scopus)

TGF-β-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

Mohammad, K., Javelaud, D., Fournier, P. G. J., Niewolna, M., McKenna, C. R., Peng, X. H., Duong, V., Dunn, L. K., Mauviel, A. & Guise, T., Jan 1 2011, In : Cancer Research. 71, 1, p. 175-184 10 p.

Research output: Contribution to journalArticle

Melanoma
Phosphotransferases
Neoplasm Metastasis
Bone and Bones
Bone Development
21 Citations (Scopus)

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

Wu, X., Chen, S., He, Y., Rhodes, S. D., Mohammad, K., Li, X., Yang, X., Jiang, L., Nalepa, G., Snider, P., Robling, A., Clapp, D., Conway, S., Guise, T. & Yang, F. C., Sep 29 2011, In : PLoS One. 6, 9, e24917.

Research output: Contribution to journalArticle

Spontaneous Fractures
Neurofibromatosis 1
stem cells
Repair
animal models
9 Citations (Scopus)

The reaction of bone to tumor growth from human breast cancer cells in a rat spine single metastasis model

Liang, H., Ma, S. Y., Mohammad, K., Guise, T., Balian, G. & Shen, F. H., Apr 1 2011, In : Spine. 36, 7, p. 497-504 8 p.

Research output: Contribution to journalArticle

Spine
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
X-Ray Microtomography
2010
116 Citations (Scopus)

GLI2-mediated melanoma invasion and metastasis

Alexaki, V. I., Javelaud, D., Van Kempen, L. C. L., Mohammad, K., Dennler, S., Luciani, F., Hoek, K. S., Jurez, P., Goydos, J. S., Fournier, P. J., Sibon, C., Bertolotto, C., Verrecchia, F., Saule, S., Delmas, V., Ballotti, R., Larue, L., Saiag, P., Guise, T. & Mauviel, A., Aug 4 2010, In : Journal of the National Cancer Institute. 102, 15, p. 1148-1159 12 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
Transforming Growth Factors
Cadherins
Reverse Transcription
2009
5 Citations (Scopus)

Agents targeting prostate cancer bone metastasis

Mohammad, K., Fournier, P. G., Guise, T. & Chirgwin, J., 2009, In : Anti-Cancer Agents in Medicinal Chemistry. 9, 10, p. 1079-1088 10 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
Morbidity
136 Citations (Scopus)

Hypoxia and TGF-β drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment

Dunn, L. K., Mohammad, K., Fournier, P. G. J., McKenna, C. R., Davis, H. W., Niewolna, M., Peng, X. H., Chirgwin, J. & Guise, T., Sep 3 2009, In : PLoS One. 4, 9, e6896.

Research output: Contribution to journalArticle

Cellular Microenvironment
Bone Neoplasms
transforming growth factors
Transforming Growth Factors
metastasis