Khalid Mohammad

  • 3719 Citations
  • 26 h-Index
19992020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

Filter
Article
2020
2019

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

Saito, H., Gasser, A., Bolamperti, S., Maeda, M., Matthies, L., Jähn, K., Long, C. L., Schlüter, H., Kwiatkowski, M., Saini, V., Pajevic, P. D., Bellido, T., van Wijnen, A. J., Mohammad, K. S., Guise, T. A., Taipaleenmäki, H. & Hesse, E., Dec 1 2019, In : Nature communications. 10, 1, 1354.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

Petrusca, D. N., Toscani, D., Wang, F. M., Park, C., Crean, C. D., Anderson, J. L., Marino, S., Mohammad, K. S., Zhou, D., Silbermann, R., Sun, Q., Kurihara, N., Galson, D. L., Giuliani, N. & Roodman, G. D., Oct 4 2018, In : Journal of Hematology and Oncology. 11, 1, 123.

Research output: Contribution to journalArticle

2 Scopus citations

Improved autologous cortical bone harvest and viability with 2Flute otologic burs

Roth, A. A., Tang, P. C., Ye, M. J., Mohammad, K. S. & Nelson, R. F., Jan 2018, In : Laryngoscope. 128, 1, p. E40-E46

Research output: Contribution to journalArticle

2017

Aromatase inhibitor-induced bone loss increases the progression of estrogen receptor-negative breast cancer in bone and exacerbates muscle weakness in vivo

Wright, L. E., Harhash, A. A., Kozlow, W. M., Waning, D. L., Regan, J. N., She, Y., John, S. K., Murthy, S., Niewolna, M., Marks, A. R., Mohammad, K. S. & Guise, T. A., Jan 1 2017, In : Oncotarget. 8, 5, p. 8406-8419 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Bone-induced expression of integrin b3 enables targeted nanotherapy of breast cancer metastases

Ross, M. H., Esser, A. K., Fox, G. C., Schmieder, A. H., Yang, X., Hu, G., Pan, D., Su, X., Xu, Y., Novack, D. V., Walsh, T., Colditz, G. A., Lukaszewicz, G. H., Cordell, E., Novack, J., Fitzpatrick, J. A. J., Waning, D. L., Mohammad, K. S., Guise, T. A., Lanza, G. M. & 1 others, Weilbaecher, K. N., Nov 15 2017, In : Cancer Research. 77, 22, p. 6299-6312 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Differential bone loss in mouse models of colon cancer cachexia

Bonetto, A., Kays, J. K., Parker, V. A., Matthews, R. R., Barreto, R., Puppa, M. J., Kang, K. S., Carson, J. A., Guise, T. A., Mohammad, K. S., Robling, A. G., Couch, M. E., Koniaris, L. G. & Zimmers, T. A., Jan 1 2017, In : Frontiers in Physiology. 7, JAN, 679.

Research output: Contribution to journalArticle

14 Scopus citations

Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

Juárez, P., Fournier, P. G. J., Mohammad, K. S., McKenna, R. C., Davis, H. W., Peng, X. H., Niewolna, M., Mauviel, A., Chirgwin, J. M. & Guise, T. A., Oct 17 2017, In : Oncotarget. 8, 49, p. 86447-86462 16 p.

Research output: Contribution to journalArticle

7 Scopus citations

Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells

Singh, P., Hoggatt, J., Kamocka, M., Mohammad, K., Saunders, M. R., Li, H., Speth, J., Carlesso, N., Guise, T. & Pelus, L., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4527-4540 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Osteocyte-Intrinsic TGF-β Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling

Dole, N. S., Mazur, C. M., Acevedo, C., Lopez, J. P., Monteiro, D. A., Fowler, T. W., Gludovatz, B., Walsh, F., Regan, J. N., Messina, S., Evans, D. S., Lang, T. F., Zhang, B., Ritchie, R. O., Mohammad, K. S. & Alliston, T., Nov 28 2017, In : Cell Reports. 21, 9, p. 2585-2596 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Osteolytic breast cancer causes skeletal muscle weakness in an immunocompetent syngeneic mouse model

Regan, J. N., Mikesell, C., Reiken, S., Xu, H., Marks, A. R., Mohammad, K. S., Guise, T. A. & Waning, D. L., Dec 19 2017, In : Frontiers in Endocrinology. 8, DEC, 358.

Research output: Contribution to journalArticle

4 Scopus citations

The P2Y2 nucleotide receptor is an inhibitor of vascular calcification

Qian, S., Regan, J., Shelton, M. T., Hoggatt, A., Mohammad, K., Herring, B. & Seye, C., Feb 1 2017, In : Atherosclerosis. 257, p. 38-46 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

Trivedi, T., Zheng, Y., Fournier, P. G. J., Murthy, S., John, S., Schillo, S., Dunstan, C. R., Mohammad, K. S., Zhou, H., Seibel, M. J. & Guise, T. A., Jan 1 2017, In : Oncotarget. 8, 16, p. 26687-26701 15 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016
71 Scopus citations

Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo

Teramachi, J., Silbermann, R., Yang, P., Zhao, W., Mohammad, K. S., Guo, J., Anderson, J. L., Zhou, D., Feng, R., Myint, K. Z., Maertz, N., Beumer, J. H., Eiseman, J. L., Windle, J. J., Xie, X. Q., Roodman, G. D. & Kurihara, N., Feb 1 2016, In : Leukemia. 30, 2, p. 390-398 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cell adhesion molecule CD166 drives malignant progression and osteolytic disease in multiple myeloma

Xu, L., Mohammad, K. S., Wu, H., Crean, C., Poteat, B., Cheng, Y., Cardoso, A. A., Machal, C., Hanenberg, H., Abonour, R., Kacena, M. A., Chirgwin, J., Suvannasankha, A. & Srour, E. F., Dec 1 2016, In : Cancer Research. 76, 23, p. 6901-6910 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Hypercalcemia of malignancy: A new twist on an old problem

Mohammad, K. & Guise, T., May 1 2016, In : Journal of Oncology Practice. 12, 5, p. 435-436 2 p.

Research output: Contribution to journalArticle

Loss of Asxl1 alters self-renewal and cell fate of bone marrow stromal cell, leading to bohring-opitz-like syndrome in mice

Zhang, P., Xing, C., Rhodes, S. D., He, Y., Deng, K., Li, Z., He, F., Zhu, C., Nguyen, L., Zhou, Y., Chen, S., Mohammad, K. S., Guise, T. A., Abdel-Wahab, O., Xu, M., Wang, Q. F. & Yang, F. C., Jun 14 2016, In : Stem Cell Reports. 6, 6, p. 914-925 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease

Teramachi, J., Nagata, Y., Mohammad, K., Inagaki, Y., Ohata, Y., Guise, T., Michou, L., Brown, J. P., Windle, J. J., Kurihara, N. & Roodman, G. D., Mar 1 2016, In : Journal of Clinical Investigation. 126, 3, p. 1012-1022 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
2015

Dystrophic spinal deformities in a neurofibromatosis type 1 murine model

Rhodes, S. D., Zhang, W., Yang, D., Yang, H., Chen, S., Wu, X., Li, X., Yang, X., Mohammad, K. S., Guise, T. A., Bergner, A. L., Stevenson, D. A. & Yang, F. C., Mar 18 2015, In : PloS one. 10, 3, e0119093.

Research output: Contribution to journalArticle

5 Scopus citations

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

Waning, D. L., Mohammad, K. S., Reiken, S., Xie, W., Andersson, D. C., John, S., Chiechi, A., Wright, L. E., Umanskaya, A., Niewolna, M., Trivedi, T., Charkhzarrin, S., Khatiwada, P., Wronska, A., Haynes, A., Benassi, M. S., Witzmann, F. A., Zhen, G., Wang, X., Cao, X. & 3 others, Roodman, G. D., Marks, A. R. & Guise, T. A., Nov 1 2015, In : Nature Medicine. 21, 11, p. 1262-1271 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

Nf1 haploinsufficiency alters myeloid lineage commitment and function, leading to deranged skeletal homeostasis

Rhodes, S. D., Yang, H., Dong, R., Menon, K., He, Y., Li, Z., Chen, S., Staser, K. W., Jiang, L., Wu, X., Yang, X., Peng, X., Mohammad, K. S., Guise, T. A., Xu, M. & Yang, F. C., Oct 1 2015, In : Journal of Bone and Mineral Research. 30, 10, p. 1840-1851 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

Wu, C., Rankin, E. B., Castellini, L., Fernandez-Alcudia, J., Lagory, E. L., Andersen, R., Rhodes, S. D., Wilson, T. L. S., Mohammad, K. S., Castillo, A. B., Guise, T. A., Schipani, E. & Giaccia, A. J., Jan 1 2015, In : Genes and Development. 29, 8, p. 817-831 15 p.

Research output: Contribution to journalArticle

32 Scopus citations

Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model

Wright, L. E., Buijs, J. T., Kim, H. S., Coats, L. E., Scheidler, A. M., John, S. K., She, Y., Murthy, S., Ma, N., Chin-Sinex, H. J., Bellido, T. M., Bateman, T. A., Mendonca, M. S., Mohammad, K. S. & Guise, T. A., Jul 1 2015, In : Journal of Bone and Mineral Research. 30, 7, p. 1268-1279 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; The effect of pharmacological targeting TGFβ receptor i kinase

Buijs, J. T., Matula, K. M., Cheung, H., Kruithof-De Julio, M., Van Der Mark, M. H., Snoeks, T. J., Cohen, R., Corver, W. E., Mohammad, K. S., Jonkers, J., Guise, T. A. & Van Der Pluijm, G., Apr 1 2015, In : Journal of Pathology. 235, 5, p. 745-759 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

Fournier, P. G. J., Juárez, P., Jiang, G., Clines, G. A., Niewolna, M., Kim, H. S., Walton, H. W., Peng, X. H., Liu, Y., Mohammad, K. S., Wells, C. D., Chirgwin, J. M. & Guise, T. A., Jun 8 2015, In : Cancer Cell. 27, 6, p. 809-821 13 p.

Research output: Contribution to journalArticle

97 Scopus citations

Tip110 regulates the cross talk between p53 and hypoxia-inducible factor 1α under hypoxia and promotes survival of cancer cells

Timani, K. A., Liu, Y., Fan, Y., Mohammad, K. S. & He, J. J., Jan 1 2015, In : Molecular and cellular biology. 35, 13, p. 2254-2264 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Generation of the first autosomal dominant osteopetrosis type II (ADO2) disease models

Alam, I., Gray, A. K., Chu, K., Ichikawa, S., Mohammad, K. S., Capannolo, M., Capulli, M., Maurizi, A., Muraca, M., Teti, A., Econs, M. J. & Del Fattore, A., Feb 2014, In : Bone. 59, p. 66-75 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis

Siclari, V. A., Mohammad, K. S., Tompkins, D. R., Davis, H., McKenna, C. R., Peng, X., Wessner, L. L., Niewolna, M., Guise, T. A., Suvannasankha, A. & Chirgwin, J. M., Dec 2 2014, In : Breast Cancer Research. 16, 1, 458.

Research output: Contribution to journalArticle

18 Scopus citations
2013

Curcuminoids block TGF-β signaling in human breast cancer cells and limit osteolysis in a murine model of breast cancer bone metastasis

Wright, L. E., Frye, J. B., Lukefahr, A. L., Timmermann, B. N., Mohammad, K. S., Guise, T. A. & Funk, J. L., Mar 22 2013, In : Journal of Natural Products. 76, 3, p. 316-321 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Differential stem-and progenitor-cell trafficking by prostaglandin e 2

Hoggatt, J., Mohammad, K. S., Singh, P., Hoggatt, A. F., Chitteti, B. R., Speth, J. M., Hu, P., Poteat, B. A., Stilger, K. N., Ferraro, F., Silberstein, L., Wong, F. K., Farag, S. S., Czader, M., Milne, G. L., Breyer, R. M., Serezani, C. H., Scadden, D. T., Guise, T. A., Srour, E. F. & 1 others, Pelus, L. M., Mar 21 2013, In : Nature. 495, 7441, p. 365-369 5 p.

Research output: Contribution to journalArticle

79 Scopus citations

Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model

Rhodes, S. D., Wu, X., He, Y., Chen, S., Yang, H., Staser, K. W., Wang, J., Zhang, P., Jiang, C., Yokota, H., Dong, R., Peng, X., Yang, X., Murthy, S., Azhar, M., Mohammad, K. S., Xu, M., Guise, T. A. & Yang, F. C., Dec 1 2013, In : Journal of Bone and Mineral Research. 28, 12, p. 2476-2489 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness

Hoggatt, J., Mohammad, K. S., Singh, P. & Pelus, L. M., Jan 1 2013, In : Blood. 122, 17, p. 2997-3000 4 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

RANKL/RANK/MMP-1 Molecular Triad Contributes to the Metastatic Phenotype of Breast and Prostate Cancer Cells In Vitro

Casimiro, S., Mohammad, K. S., Pires, R., Tato-Costa, J., Alho, I., Teixeira, R., Carvalho, A., Ribeiro, S., Lipton, A., Guise, T. A. & Costa, L., May 16 2013, In : PLoS ONE. 8, 5, e63153.

Research output: Contribution to journalArticle

46 Scopus citations
2012

c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions

He, Y., Rhodes, S. D., Chen, S., Wu, X., Yuan, J., Yang, X., Jiang, L., Li, X., Takahashi, N., Xu, M., Mohammad, K. S., Guise, T. A. & Yang, F. C., Nov 7 2012, In : PLoS ONE. 7, 11, e46900.

Research output: Contribution to journalArticle

15 Scopus citations

Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat pad

Nickerson, N. K., Mohammad, K. S., Gilmore, J. L., Crismore, E., Bruzzaniti, A., Guise, T. A. & Foley, J., Jan 19 2012, In : PloS one. 7, 1, e30255.

Research output: Contribution to journalArticle

24 Scopus citations

Halofuginone inhibits the establishment and progression of melanoma bone metastases

Juaŕez, P., Mohammad, K. S., Yin, J. J., Fournier, P. G. J., McKenna, R. C., Davis, H. W., Peng, X. H., Niewolna, M., Javelaud, D., Chirgwin, J. M., Mauviel, A. & Guise, T. A., Dec 1 2012, In : Cancer Research. 72, 23, p. 6247-6256 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

Pollari, S., Käkönen, R. S., Mohammad, K. S., Rissanen, J. P., Halleen, J. M., Wärri, A., Nissinen, L., Pihlavisto, M., Marjamäki, A., Perälä, M., Guise, T. A., Kallioniemi, O. & Käkönen, S. M., May 1 2012, In : Molecular Cancer Research. 10, 5, p. 597-604 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Tissue transglutaminase links TGF-Β, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer

Cao, L., Shao, M., Schilder, J., Guise, T., Mohammad, K. S. & Matei, D., May 17 2012, In : Oncogene. 31, 20, p. 2521-2534 14 p.

Research output: Contribution to journalArticle

125 Scopus citations
2011

Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor

Clines, G. A., Mohammad, K. S., Grunda, J. M., Clines, K. L., Niewolna, M., McKenna, C. R., McKibbin, C. R., Yanagisawa, M., Suva, L. J., Chirgwin, J. M. & Guise, T. A., Oct 1 2011, In : Journal of Bone and Mineral Research. 26, 10, p. 2523-2536 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Tetra-methoxystilbene modulates ductal growth of the developing murine mammary gland

Kim, T., Park, H., Yue, W., Wang, J. P., Atkins, K. A., Zhang, Z., Rogan, E. G., Cavalieri, E. L., Mohammad, K. S., Kim, S., Santen, R. J. & Aiyar, S. E., Apr 1 2011, In : Breast Cancer Research and Treatment. 126, 3, p. 779-789 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

TGF-β-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

Mohammad, K. S., Javelaud, D., Fournier, P. G. J., Niewolna, M., McKenna, C. R., Peng, X. H., Duong, V., Dunn, L. K., Mauviel, A. & Guise, T. A., Jan 1 2011, In : Cancer Research. 71, 1, p. 175-184 10 p.

Research output: Contribution to journalArticle

140 Scopus citations

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

Wu, X., Chen, S., He, Y., Rhodes, S. D., Mohammad, K. S., Li, X., Yang, X., Jiang, L., Nalepa, G., Snider, P., Robling, A. G., Clapp, D. W., Conway, S. J., Guise, T. A. & Yang, F. C., Sep 29 2011, In : PLoS ONE. 6, 9, e24917.

Research output: Contribution to journalArticle

22 Scopus citations

The reaction of bone to tumor growth from human breast cancer cells in a rat spine single metastasis model

Liang, H., Ma, S. Y., Mohammad, K., Guise, T. A., Balian, G. & Shen, F. H., Apr 1 2011, In : Spine. 36, 7, p. 497-504 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2010

GLI2-mediated melanoma invasion and metastasis

Alexaki, V. I., Javelaud, D., Van Kempen, L. C. L., Mohammad, K. S., Dennler, S., Luciani, F., Hoek, K. S., Jurez, P., Goydos, J. S., Fournier, P. J., Sibon, C., Bertolotto, C., Verrecchia, F., Saule, S., Delmas, V., Ballotti, R., Larue, L., Saiag, P., Guise, T. A. & Mauviel, A., Aug 4 2010, In : Journal of the National Cancer Institute. 102, 15, p. 1148-1159 12 p.

Research output: Contribution to journalArticle

118 Scopus citations
2009

Hypoxia and TGF-β drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment

Dunn, L. K., Mohammad, K. S., Fournier, P. G. J., McKenna, C. R., Davis, H. W., Niewolna, M., Peng, X. H., Chirgwin, J. M. & Guise, T. A., Sep 3 2009, In : PLoS ONE. 4, 9, e6896.

Research output: Contribution to journalArticle

140 Scopus citations

Pharmacologic inhibition of the TGF-β type I receptor kinase has anabolic and anti-catabolic effects on bone

Mohammad, K. S., Chen, C. G., Balooch, G., Stebbins, E., McKenna, C. R., Davis, H., Niewolna, M., Peng, X. H., Nguyen, D. H. N., Ionova-Martin, S. S., Bracey, J. W., Hogue, W. R., Wong, D. H., Ritchie, R. O., Suva, L. J., Derynck, R., Guise, T. A. & Alliston, T., Apr 16 2009, In : PLoS ONE. 4, 4, e5275.

Research output: Contribution to journalArticle

110 Scopus citations
2007

Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation

Clines, G. A., Mohammad, K. S., Bao, Y., Stephens, O. W., Suva, L. J., Shaughnessy, J. D., Fox, J. W., Chirgwin, J. M. & Guise, T. A., Feb 1 2007, In : Molecular Endocrinology. 21, 2, p. 486-498 13 p.

Research output: Contribution to journalArticle

133 Scopus citations

Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis

Javelaud, D., Mohammad, K. S., McKenna, C. R., Fournier, P., Luciani, F., Niewolna, M., André, J., Delmas, V., Larue, L., Guise, T. A. & Mauviel, A., Mar 1 2007, In : Cancer Research. 67, 5, p. 2317-2324 8 p.

Research output: Contribution to journalArticle

145 Scopus citations
2005

Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-κB ligand pathway

Bendre, M. S., Margulies, A. G., Walser, B., Akel, N. S., Bhattacharrya, S., Skinner, R. A., Swain, F., Ramani, V., Mohammad, K. S., Wessner, L. L., Martinez, A., Guise, T. A., Chirgwin, J. M., Gaddy, D. & Suva, L. J., Dec 1 2005, In : Cancer Research. 65, 23, p. 11001-11009 9 p.

Research output: Contribution to journalArticle

180 Scopus citations