Liang Cheng

  • 29511 Citations
  • 84 h-Index
19962020

Research output per year

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Publications

2020

An evaluation of current prostate cancer diagnostic approaches with emphasis on liquid biopsies and prostate cancer

Mollica, V., Di Nunno, V., Santoni, M., Cimadamore, A., Scarpelli, M., Lopez-Beltran, A., Cheng, L., Mariani, C., Battelli, N., Montironi, R. & Massari, F., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 207-217 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Clinicopathologic analysis of upper urinary tract carcinoma with variant histology

Rolim, I., Henriques, V., Rolim, N., Blanca, A., Marques, R. C., Volavšek, M., Carvalho, I., Montironi, R., Cimadamore, A., Raspollini, M. R., Cheng, L. & Lopez-Beltran, A., Jan 1 2020, (Accepted/In press) In : Virchows Archiv.

Research output: Contribution to journalArticle

Comprehensive characterisation of pancreatic ductal adenocarcinoma with microsatellite instability: histology, molecular pathology and clinical implications

Luchini, C., Brosens, L. A. A., Wood, L. D., Chatterjee, D., Shin, J. I., Sciammarella, C., Fiadone, G., Malleo, G., Salvia, R., Kryklyva, V., Piredda, M. L., Cheng, L., Lawlor, R. T., Adsay, V. & Scarpa, A., Jan 1 2020, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

Open Access

Computational analysis of pathological images enables a better diagnosis of TFE3 Xp11.2 translocation renal cell carcinoma

Cheng, J., Han, Z., Mehra, R., Shao, W., Cheng, M., Feng, Q., Ni, D., Huang, K., Cheng, L. & Zhang, J., Dec 1 2020, In : Nature communications. 11, 1, 1778.

Research output: Contribution to journalArticle

Open Access

Current and emerging bladder cancer biomarkers with an emphasis on urine biomarkers

Lopez-Beltran, A., Cheng, L., Gevaert, T., Blanca, A., Cimadamore, A., Santoni, M., Massari, F., Scarpelli, M., Raspollini, M. R. & Montironi, R., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 231-243 13 p.

Research output: Contribution to journalReview article

Epigenetic modulations and lineage plasticity in advanced prostate cancer

Ge, R., Wang, Z., Montironi, R., Jiang, Z., Cheng, M., Santoni, M., Huang, K., Massari, F., Lu, X., Cimadamore, A., Lopez-Beltran, A. & Cheng, L., Apr 2020, In : Annals of Oncology. 31, 4, p. 470-479 10 p.

Research output: Contribution to journalReview article

Five decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia

MacLennan, G. T. & Cheng, L., Jan 2020, In : Human pathology. 95, p. 24-45 22 p.

Research output: Contribution to journalArticle

1 Scopus citations

Germline and somatic mutations in prostate cancer: Focus on defective DNA repair, PARP inhibitors and immunotherapy

Cimadamore, A., Lopez-Beltran, A., Massari, F., Santoni, M., Mazzucchelli, R., Scarpelli, M., Galosi, A. B., Cheng, L. & Montironi, R., Jan 1 2020, In : Future Oncology. 16, 5, p. 75-80 6 p.

Research output: Contribution to journalComment/debate

Gonadoblastoma: origin and outcome

Roth, L. M. & Cheng, L., Jan 1 2020, (Accepted/In press) In : Human pathology.

Research output: Contribution to journalArticle

Immunotherapy for urothelial cancer: from the diagnostic pathologist’s point of view

Cimadamore, A., Scarpelli, M., Massari, F., Eckstein, M., Gevaert, T., Cheng, L., Lopez-Beltran, A. & Montironi, R., Jun 2 2020, In : Expert Opinion on Biological Therapy. 20, 6, p. 539-544 6 p.

Research output: Contribution to journalEditorial

Open Access

Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded

Samaratunga, H., Delahunt, B., Egevad, L., Srigley, J. R., Billis, A., Bostwick, D. G., Camparo, P., Cheng, L., Clouston, D., Denham, J., Furusato, B., Hartmann, A., Jufe, L., Kench, J., Kenwright, D. N., Kristiansen, G., Leite, K. R. M., MacLennan, G. T., Merrimen, J., Moch, H. & 11 others, Oxley, J., Pan, C. C., Paner, G., Ro, J., Sesterhenn, I. A. M., Shanks, J., Thunders, M., Tsuzuki, T., Wheeler, T., Yaxley, J. W. & Varma, M., Feb 2020, In : Pathology. 52, 2, p. 192-196 5 p.

Research output: Contribution to journalReview article

Liquid biopsies in urological cancers: what we need to know before starting using them

Franceschini, T., Giunchi, F., Montironi, R., Scarpelli, M., Lopez-Beltran, A., Cheng, L. & Fiorentino, M., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 135-139 5 p.

Research output: Contribution to journalEditorial

Open Access

Liquid biopsy in germ cell tumors: biology and clinical management

Chovanec, M., Kalavska, K., Mego, M. & Cheng, L., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 187-194 8 p.

Research output: Contribution to journalReview article

2 Scopus citations

Liquid biopsy in the clinical management of bladder cancer: current status and future developments

Kouba, E., Lopez-Beltran, A., Montironi, R., Massari, F., Huang, K., Santoni, M., Chovanec, M., Cheng, M., Scarpelli, M., Zhang, J., Cimadamore, A. & Cheng, L., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 255-264 10 p.

Research output: Contribution to journalReview article

Microsatellite instability and mismatch repair deficiency in the era of precision immuno-oncology

Mann, S. A. & Cheng, L., Jan 2 2020, In : Expert Review of Anticancer Therapy. 20, 1, p. 1-4 4 p.

Research output: Contribution to journalEditorial

Open Access

Molecular characteristics of testicular germ cell tumors: pathogenesis and mechanisms of therapy resistance

Al-Obaidy, K. I., Chovanec, M. & Cheng, L., Feb 1 2020, In : Expert Review of Anticancer Therapy. 20, 2, p. 75-79 5 p.

Research output: Contribution to journalEditorial

Open Access

Molecular characterization and diagnostic criteria of renal cell carcinoma with emphasis on liquid biopsies

Cimadamore, A., Massari, F., Santoni, M., Mollica, V., Di Nunno, V., Cheng, L., Lopez-Beltran, A., Scarpelli, M., Montironi, R. & Moch, H., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 141-150 10 p.

Research output: Contribution to journalReview article

Molecular diagnostics in uro-oncology

Montironi, R., Cheng, L., Cimadamore, A. & Lopez-Beltran, A., Jan 1 2020, (Accepted/In press) In : Expert Review of Molecular Diagnostics.

Research output: Contribution to journalEditorial

Open Access

Morphologic, Molecular and Clinical Features of Aggressive Variant Prostate Cancer

Montironi, R., Cimadamore, A., Lopez-Beltran, A., Scarpelli, M., Aurilio, G., Santoni, M., Massari, F. & Cheng, L., Apr 25 2020, In : Cells. 9, 5

Research output: Contribution to journalReview article

Open Access

Polymorphonuclear MDSCs are enriched in the stroma and expanded in metastases of prostate cancer

Wen, J., Huang, G., Liu, S., Wan, J., Wang, X., Zhu, Y., Kaliney, W., Zhang, C., Cheng, L., Wen, X. & Lu, X., Jan 1 2020, (Accepted/In press) In : Journal of Pathology: Clinical Research.

Research output: Contribution to journalArticle

Open Access

pT1 high-grade bladder cancer: histologic criteria, pitfalls in the assessment of invasion, and substaging

Raspollini, M. R., Montironi, R., Mazzucchelli, R., Cimadamore, A., Cheng, L. & Lopez-Beltran, A., Jan 1 2020, (Accepted/In press) In : Virchows Archiv.

Research output: Contribution to journalReview article

Re: Multi-institutional Re-evaluation of Prognostic Factors in Chromophobe Renal Cell Carcinoma: Proposal of a Novel Two-tiered Grading Scheme

Cimadamore, A., Cheng, L., Ohashi, R., Scarpelli, M., Lopez-Beltran, A., Moch, H. & Montironi, R., Jan 1 2020, (Accepted/In press) In : European urology.

Research output: Contribution to journalComment/debate

Re: Maria Chiara Sighinolfi, Bernardo Rocco's Words of Wisdom re: EAU Guidelines: Prostate Cancer 2019. Mottet N, van den Bergh RCN, Briers E, et al. https://uroweb.org/guideline/prostate-Cancer/. Eur Urol 2019;76:871

Cimadamore, A., Scarpelli, M., Cheng, L., Lopez-Beltran, A., Galosi, A. B., Montorsi, F. & Montironi, R., May 2020, In : European urology. 77, 5, p. e122-e127

Research output: Contribution to journalLetter

Renal Cell Carcinoma: genomic landscape and clinical implications

Aurilio, G., Santoni, M., Cimadamore, A., Massari, F., Scarpelli, M., Lopez-Beltran, A., Cheng, L., Battelli, N., Nolé, F. & Montironi, R., Mar 3 2020, In : Expert Review of Precision Medicine and Drug Development. 5, 2, p. 95-100 6 p.

Research output: Contribution to journalReview article

Renal cell tumors with an entrapped papillary component: a collision with predilection for oncocytic tumors

Williamson, S. R., Cheng, L., Gadde, R., Giannico, G. A., Wasco, M. J., Taylor Smith, P. J., Gupta, N. S., Grignon, D. J., Jorda, M. & Kryvenko, O. N., Mar 1 2020, In : Virchows Archiv. 476, 3, p. 399-407 9 p.

Research output: Contribution to journalArticle

Report from the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. II. Molecular Pathology of Bladder Cancer: Progress and Challenges

Warrick, J. I., Knowles, M. A., Yves, A., Van Der Kwast, T., Grignon, D. J., Kristiansen, G., Egevad, L., Hartmann, A. & Cheng, L., Jan 1 2020, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Sequential or Concomitant Inhibition of Cyclin-Dependent Kinase 4/6 Before mTOR Pathway in Hormone-Positive HER2 Negative Breast Cancer: Biological Insights and Clinical Implications

Occhipinti, G., Romagnoli, E., Santoni, M., Cimadamore, A., Sorgentoni, G., Cecati, M., Giulietti, M., Battelli, N., Maccioni, A., Storti, N., Cheng, L., Principato, G., Montironi, R. & Piva, F., Apr 15 2020, In : Frontiers in Genetics. 11, 349.

Research output: Contribution to journalReview article

Open Access

The applicability and utility of immunohistochemical biomarkers in bladder pathology

Akgul, M., MacLennan, G. T. & Cheng, L., Apr 2020, In : Human pathology. 98, p. 32-55 24 p.

Research output: Contribution to journalArticle

1 Scopus citations

The expanding molecular and mutational landscape of nested variant of urothelial carcinoma

Levy, D. R. & Cheng, L., Apr 1 2020, In : Histopathology. 76, 5, p. 638-639 2 p.

Research output: Contribution to journalEditorial

The Utility of ERBB4 and RB1 Immunohistochemistry in Distinguishing Chromophobe Renal Cell Carcinoma From Renal Oncocytoma

Sun, T., Hutchinson, L., Zhou, A. G., Liu, Q., Cosar, E. F., St. Cyr, M., Ninteau, N., Dresser, K., Cheng, L., Jiang, Z. & Cornejo, K. M., May 1 2020, In : International Journal of Surgical Pathology. 28, 3, p. 259-264 6 p.

Research output: Contribution to journalArticle

Validation of a neuroendocrine-like classifier confirms poor outcomes in patients with bladder cancer treated with cisplatin-based neoadjuvant chemotherapy

Grivas, P., Bismar, T. A., Alva, A. S., Huang, H. C., Liu, Y., Seiler, R., Alimohamed, N., Cheng, L., Hyndman, M. E., Dabbas, B., Black, P. C., Davicioni, E., Wright, J. L., Ornstein, M. C., Mian, O. Y., Kaimakliotis, H. Z., Gibb, E. A. & Lotan, Y., Apr 2020, In : Urologic Oncology: Seminars and Original Investigations. 38, 4, p. 262-268 7 p.

Research output: Contribution to journalArticle

2019
1 Scopus citations

Activating KRAS mutations in arteriovenous malformations of the brain: frequency and clinicopathologic correlation

Priemer, D. S., Vortmeyer, A. O., Zhang, S., Chang, H. Y., Curless, K. L. & Cheng, L., Jul 2019, In : Human pathology. 89, p. 33-39 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: A systematic review with meta-analysis

Lawlor, R. T., Veronese, N., Pea, A., Nottegar, A., Smith, L., Pilati, C., Demurtas, J., Fassan, M., Cheng, L. & Luchini, C., Mar 14 2019, In : BMC Cancer. 19, 1, 232.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations

Annual review issue: Urologic pathology: a remarkable journey of innovation

Cheng, L. & Berney, D. M., Jan 1 2019, In : Histopathology. 74, 1, 1 p.

Research output: Contribution to journalEditorial

A Systematic Review of the Role of Definitive Local Treatment in Patients with Clinically Lymph Node-positive Prostate Cancer

Ventimiglia, E., Seisen, T., Abdollah, F., Briganti, A., Fonteyne, V., James, N., Roach, M., Thalmann, G. N., Touijer, K., Chen, R. C. & Cheng, L., May 1 2019, In : European urology oncology. 2, 3, p. 294-301 8 p.

Research output: Contribution to journalReview article

4 Scopus citations

Circulating tumor cells in renal cell carcinoma: Recent findings and future challenges

Santoni, M., Cimadamore, A., Cheng, L., Lopez-Beltran, A., Battelli, N., Massari, F., Scarpelli, M., Galosi, A. B., Bracarda, S. & Montironi, R., Jan 1 2019, In : Frontiers in Oncology. 9, APR, 228.

Research output: Contribution to journalComment/debate

Open Access
6 Scopus citations

Clinical utility versus futility: A tipping point for liquid biopsies in bladder cancer

Kouba, E. & Cheng, L., Jan 1 2019, In : Future Oncology. 15, 33, p. 3751-3753 3 p.

Research output: Contribution to journalReview article

Open Access

Clinicopathological characteristics of ypT0N0 urothelial carcinoma following neoadjuvant chemotherapy and cystectomy

Magers, M. J., Kaimakliotis, H. Z., Barboza, M. P., Bandali, E., Adra, N., Koch, M. O. & Cheng, L., Aug 1 2019, In : Journal of clinical pathology. 72, 8, p. 550-553 4 p.

Research output: Contribution to journalArticle

Contemporary best practice in the management of urothelial carcinomas of the renal pelvis and ureter

Bianconi, M., Cimadamore, A., Faloppi, L., Scartozzi, M., Santoni, M., Lopez-Beltran, A., Cheng, L., Scarpelli, M. & Montironi, R., Jan 1 2019, In : Therapeutic Advances in Urology. 11

Research output: Contribution to journalReview article

1 Scopus citations

Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians

Gasparrini, S., Cimadamore, A., Scarpelli, M., Massari, F., Doria, A., Mazzucchelli, R., Cheng, L., Lopez-Beltran, A. & Montironi, R., Jan 1 2019, In : Asian Journal of Andrology. 21, 1, p. 19-23 5 p.

Research output: Contribution to journalReview article

1 Scopus citations

Controversial issues in Gleason and International Society of Urological Pathology (ISUP) prostate cancer grading: proposed recommendations for international implementation

Srigley, J. R., Delahunt, B., Samaratunga, H., Billis, A., Cheng, L., Clouston, D., Evans, A., Furusato, B., Kench, J., Leite, K., MacLennan, G., Moch, H., Pan, C. C., Rioux-Leclercq, N., Ro, J., Shanks, J., Shen, S., Tsuzuki, T., Varma, M., Wheeler, T. & 2 others, Yaxley, J. & Egevad, L., Aug 2019, In : Pathology. 51, 5, p. 463-473 11 p.

Research output: Contribution to journalReview article

3 Scopus citations

Current progress in car-t cell therapy for solid tumors

Ma, S., Li, X., Wang, X., Cheng, L., Li, Z., Zhang, C., Ye, Z. & Qian, Q., Jan 1 2019, In : International Journal of Biological Sciences. 15, 12, p. 2548-2560 13 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography

Bungart, B., Cao, Y., Yang-Tran, T., Gorsky, S., Lan, L. U., Roblyer, D., Koch, M., Cheng, L., Masterson, T. & Cheng, J. X., Mar 1 2019, In : Biomedical Optics Express. 10, 3, p. 1405-1419 15 p., 356707.

Research output: Contribution to journalArticle

2 Scopus citations

Detecting and phenotyping of aneuploid circulating tumor cells in patients with various malignancies

Ye, Z., Ding, Y., Chen, Z., Li, Z., Ma, S., Xu, Z., Cheng, L., Wang, X., Zhang, X., Ding, N., Zhang, Q. & Qian, Q., Apr 3 2019, In : Cancer Biology and Therapy. 20, 4, p. 546-551 6 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Detection of androgen receptor (AR) and AR-V7 in small cell prostate carcinoma: Diagnostic and therapeutic implications

Zhao, P., Zhu, Y., Cheng, L. & Luo, J., Jan 2019, In : Asian Journal of Urology. 6, 1, p. 109-113 5 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations