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Lindsey Mayo

  • 5724 Citations
  • 25 h-Index
19962019
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  • 2 Similar Profiles
DNA Damage Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Phosphatidylinositol 3-Kinase Medicine & Life Sciences
Proto-Oncogene Proteins c-mdm2 Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Endothelial cells Chemical Compounds
Proteins Medicine & Life Sciences

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NIH Grants 2005 2018

Regulation of Mdm2 activity by kinase signaling pathways

Mayo, L.

National Institutes of Health

7/12/13 → 4/30/18

Project: Research project

Phosphotransferases
Neoplasms
Enzymes
Half-Life
Intercellular Signaling Peptides and Proteins

Regulation of Mdm2 compartmentalization

Mayo, L.

National Institutes of Health

5/11/05 → 3/31/11

Project: Research project

Cell Nucleus Active Transport
Signal Transduction
Post Translational Protein Processing
Intercellular Signaling Peptides and Proteins
Insulin-Like Growth Factor I

Publications 1996 2019

  • 5724 Citations
  • 25 h-Index
  • 57 Article
  • 2 Chapter
  • 1 Letter
  • 1 Review article

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Chen, S., Wang, Q., Yu, H., Capitano, M. L., Vemula, S., Nabinger, S. C., Gao, R., Yao, C., Kobayashi, M., Geng, Z., Fahey, A., Henley, D., Liu, S. Z., Barajas, S., Cai, W., Wolf, E. R., Ramdas, B., Cai, Z., Gao, H., Luo, N. & 12 others, Sun, Y., Wong, T. N., Link, D. C., Liu, Y., Boswell, H. S., Mayo, L. D., Huang, G., Kapur, R., Yoder, M. C., Broxmeyer, H. E., Gao, Z. & Liu, Y., Dec 1 2019, In : Nature communications. 10, 1, 5649.

Research output: Contribution to journal › Article

Open Access
hematopoiesis
Hematopoiesis
Hematopoietic Stem Cells
Epigenomics
mutations
2 Citations (Scopus)

Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development

Nabinger, S. C., Chen, S., Gao, R., Yao, C., Kobayashi, M., Vemula, S., Fahey, A. C., Wang, C., Daniels, C., Boswell, H., Sandusky, G., Mayo, L., Kapur, R. & Liu, Y., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journal › Article

Leukemia
Cell Self Renewal
6 Citations (Scopus)

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53

Chen, S., Gao, R., Yao, C., Kobayashi, M., Liu, S. Z., Yoder, M., Broxmeyer, H., Kapur, R., Boswell, H., Mayo, L. & Liu, Y., Mar 1 2018, In : Leukemia. 32, 3, p. 850-854 5 p.

Research output: Contribution to journal › Letter

Hematopoietic Stem Cells
DNA Damage
4 Citations (Scopus)

Mutant and wild-type p53 form complexes with p73 upon phosphorylation by the kinase JNK

Wolf, E. R., McAtarsney, C. P., Bredhold, K. E., Kline, A. M. & Mayo, L., Apr 3 2018, In : Science Signaling. 11, 524, eaao4170.

Research output: Contribution to journal › Article

Phosphorylation
JNK Mitogen-Activated Protein Kinases
Phosphotransferases
Apoptosis
bcl-2-Associated X Protein
2 Citations (Scopus)

Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis

Sisti, F., Wang, S., Brandt, S. L., Glosson-Byers, N., Mayo, L., Son, Y. M., Sturgeon, S., Filgueiras, L., Jancar, S., Wong, H., Cruz, C. S. D., Andrews, N., Alves-Filho, J. C., Cunha, F. Q. & Serezani, C. H., May 1 2018, In : Science Signaling. 11, 528, eaai9085.

Research output: Contribution to journal › Article

Regulon
MicroRNAs
Phosphoric Monoester Hydrolases
Sepsis
Systemic Inflammatory Response Syndrome