Marian Pfefferkorn

  • 3276 Citations
  • 32 h-Index
20012019
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Publications 2001 2019

  • 3276 Citations
  • 32 h-Index
  • 77 Article
  • 3 Chapter
  • 1 Editorial
2019
11 Citations (Scopus)

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

Hyams, J. S., Davis Thomas, S., Gotman, N., Haberman, Y., Karns, R., Schirmer, M., Mo, A., Mack, D. R., Boyle, B., Griffiths, A. M., LeLeiko, N. S., Sauer, C. G., Keljo, D. J., Markowitz, J., Baker, S. S., Rosh, J., Baldassano, R. N., Patel, A., Pfefferkorn, M., Otley, A. & 30 others, Heyman, M., Noe, J., Oliva-Hemker, M., Rufo, P. A., Strople, J., Ziring, D., Guthery, S. L., Sudel, B., Benkov, K., Wali, P., Moulton, D., Evans, J., Kappelman, M. D., Marquis, M. A., Sylvester, F. A., Collins, M. H., Venkateswaran, S., Dubinsky, M., Tangpricha, V., Spada, K. L., Saul, B., Wang, J., Serrano, J., Hommel, K., Marigorta, U. M., Gibson, G., Xavier, R. J., Kugathasan, S., Walters, T. & Denson, L. A., Apr 27 2019, In : The Lancet. 393, 10182, p. 1708-1720 13 p.

Research output: Contribution to journalArticle

Colitis
Cohort Studies
Pediatrics
Mesalamine
Adrenal Cortex Hormones

Mental Health Screening as the Standard of Care in Pediatric Inflammatory Bowel Disease

Bennett, W. E. & Pfefferkorn, M., Jan 1 2019, (Accepted/In press) In : JAMA Pediatrics.

Research output: Contribution to journalEditorial

Standard of Care
Inflammatory Bowel Diseases
Mental Health
Pediatrics
8 Citations (Scopus)

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

Haberman, Y., Karns, R., Dexheimer, P. J., Schirmer, M., Somekh, J., Jurickova, I., Braun, T., Novak, E., Bauman, L., Collins, M. H., Mo, A., Rosen, M. J., Bonkowski, E., Gotman, N., Marquis, A., Nistel, M., Rufo, P. A., Baker, S. S., Sauer, C. G., Markowitz, J. & 22 others, Pfefferkorn, M., Rosh, J. R., Boyle, B. M., Mack, D. R., Baldassano, R. N., Shah, S., Leleiko, N. S., Heyman, M. B., Grifiths, A. M., Patel, A. S., Noe, J. D., Aronow, B. J., Kugathasan, S., Walters, T. D., Gibson, G., Thomas, S. D., Mollen, K., Shen-Orr, S., Huttenhower, C., Xavier, R. J., Hyams, J. S. & Denson, L. A., Dec 1 2019, In : Nature communications. 10, 1, 38.

Research output: Contribution to journalArticle

Open Access
Ulcerative Colitis
Transcriptome
genes
Genes
therapy
2 Citations (Scopus)

Variation in care in the management of children with Crohn's disease: Data from a multicenter inception cohort study

Krishnakumar, C., Ballengee, C. R., Liu, C., Kim, M. O., Baker, S. S., Baldassano, R. N., Cohen, S. A., Crandall, W. V., Denson, L. A., Dubinsky, M. C., Evans, J., Gokhale, R., Griffiths, A., Guthery, S. L., Oliva-Hemker, M., Heyman, M. B., Keljo, D., Kellermayer, R., Leleiko, N. S., Mack, D. R. & 15 others, Markowitz, J. F., Moulton, D. E., Noe, J. D., Otley, A. R., Patel, A. S., Pfefferkorn, M., Rabizadeh, S., Rosh, J. R., Snapper, S., Walters, T. D., Ziring, D., Mondal, K., Kappelman, M. D., Hyams, J. S. & Kugathasan, S., Jun 18 2019, In : Inflammatory bowel diseases. 25, 7, p. 1208-1217 10 p.

Research output: Contribution to journalArticle

Crohn Disease
Cohort Studies
Immunologic Factors
Colonoscopy
Steroids
2018
11 Citations (Scopus)

Biologics Delay Progression of Crohn's Disease, but Not Early Surgery, in Children

Kerur, B., Machan, J. T., Shapiro, J. M., Cerezo, C. S., Markowitz, J., Mack, D. R., Griffiths, A. M., Otley, A. R., Pfefferkorn, M., Rosh, J. R., Keljo, D. J., Boyle, B., Oliva-Hemker, M., Kay, M. H., Saeed, S. A., Grossman, A. B., Sudel, B., Kappelman, M. D., Schaefer, M., Tomer, G. & 4 others, Bousvaros, A., Lerer, T., Hyams, J. S. & LeLeiko, N. S., Jan 1 2018, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Biological Products
Crohn Disease
Disease Progression
Pediatrics
Registries
14 Citations (Scopus)

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

Schirmer, M., Denson, L., Vlamakis, H., Franzosa, E. A., Thomas, S., Gotman, N. M., Rufo, P., Baker, S. S., Sauer, C., Markowitz, J., Pfefferkorn, M., Oliva-Hemker, M., Rosh, J., Otley, A., Boyle, B., Mack, D., Baldassano, R., Keljo, D., LeLeiko, N., Heyman, M. & 8 others, Griffiths, A., Patel, A. S., Noe, J., Kugathasan, S., Walters, T., Huttenhower, C., Hyams, J. & Xavier, R. J., Oct 10 2018, In : Cell Host and Microbe. 24, 4, p. 600-610.e4

Research output: Contribution to journalArticle

Ulcerative Colitis
Therapeutics
Colectomy
Gastrointestinal Microbiome
Pediatric ulcerative colitis
3 Citations (Scopus)

Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis

Venkateswaran, S., Prince, J., Cutler, D. J., Marigorta, U. M., Okou, D. T., Prahalad, S., Mack, D., Boyle, B., Walters, T., Griffiths, A., Sauer, C. G., Leleiko, N., Keljo, D., Markowitz, J., Baker, S. S., Rosh, J., Pfefferkorn, M., Heyman, M. B., Patel, A., Otley, A. & 10 others, Baldassano, R., Noe, J., Rufo, P., Oliva-Hemker, M., Davis, S., Zwick, M. E., Gibson, G., Denson, L. A., Hyams, J. & Kugathasan, S., Mar 19 2018, In : Inflammatory Bowel Diseases. 24, 4, p. 829-838 10 p.

Research output: Contribution to journalArticle

HLA Antigens
Odds Ratio
Ulcerative Colitis
Single Nucleotide Polymorphism
Genome-Wide Association Study
6 Citations (Scopus)

Safety and Pharmacokinetic Study of Fidaxomicin in Children With Clostridium difficile-Associated Diarrhea: A phase 2A multicenter clinical trial

O'Gorman, M. A., Michaels, M. G., Kaplan, S. L., Otley, A., Kociolek, L. K., Hoffenberg, E. J., Kim, K. S., Nachman, S., Pfefferkorn, M., Sentongo, T., Sullivan, J. E. & Sears, P., Jan 1 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, 3, p. 210-218 9 p.

Research output: Contribution to journalArticle

Clostridium difficile
Multicenter Studies
Diarrhea
Pharmacokinetics
Clinical Trials

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children

Spencer, E. A., Davis, S. M., Mack, D. R., Boyle, B. M., Griffiths, A. M., Leleiko, N. S., Sauer, C. G., Keljo, D. J., Markowitz, J. F., Baker, S. S., Rosh, J. R., Baldassano, R. N., Oliva-Hemker, M., Pfefferkorn, M., Otley, A. R., Heyman, M. B., Noe, J. D., Patel, A. S., Rufo, P. A., Benkov, K. & 16 others, Evans, J., Guthery, S., Kappelman, M., Moulton, D., Strople, J., Sudel, B., Wali, P., Ziring, D., Tangpricha, V., Marquis, M. A., Walters, T. D., Collins, M. H., Kugathasan, S., Denson, L. A., Hyams, J. S. & Dubinsky, M. C., May 18 2018, In : Inflammatory Bowel Diseases. 24, 6, p. 1335-1343 9 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Serology
Phenotype
Microbial Interactions
Leukocyte L1 Antigen Complex
7 Citations (Scopus)

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn’s Disease in Children

Lindoso, L., Mondal, K., Venkateswaran, S., Somineni, H. K., Ballengee, C., Walters, T. D., Griffiths, A., Noe, J. D., Crandall, W., Snapper, S., Rabizadeh, S., Rosh, J. R., LeLeiko, N., Guthery, S., Mack, D., Kellermayer, R., Gulati, A. S., Pfefferkorn, M., Moulton, D. E., Keljo, D. & 17 others, Cohen, S., Oliva-Hemker, M., Heyman, M. B., Otley, A., Baker, S. S., Evans, J. S., Kirschner, B. S., Patel, A. S., Ziring, D., Stephens, M. C., Baldassano, R., Dubinsky, M. C., Markowitz, J., Denson, L. A., Hyams, J., Kugathasan, S. & Ananthakrishnan, A. N., Oct 1 2018, In : American Journal of Gastroenterology. 113, 10, p. 1524-1529 6 p.

Research output: Contribution to journalArticle

Environmental Exposure
Crohn Disease
Phenotype
Hospitalization
Breast Feeding
2017
13 Citations (Scopus)

Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

Hyams, J. S., Davis, S., Mack, D. R., Boyle, B., Griffiths, A. M., LeLeiko, N. S., Sauer, C. G., Keljo, D. J., Markowitz, J., Baker, S. S., Rosh, J., Baldassano, R. N., Patel, A., Pfefferkorn, M., Otley, A., Heyman, M., Noe, J., Oliva-Hemker, M., Rufo, P., Strople, J. & 23 others, Ziring, D., Guthery, S. L., Sudel, B., Benkov, K., Wali, P., Moulton, D., Evans, J., Kappelman, M. D., Marquis, A., Sylvester, F. A., Collins, M. H., Venkateswaran, S., Dubinsky, M., Tangpricha, V., Spada, K. L., Britt, A., Saul, B., Gotman, N., Wang, J., Serrano, J., Kugathasan, S., Walters, T. & Denson, L. A., Dec 1 2017, In : The Lancet Gastroenterology and Hepatology. 2, 12, p. 838-839 2 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Adrenal Cortex Hormones
Cohort Studies
Mesalamine
Therapeutics
9 Citations (Scopus)

Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed with Ulcerative Colitis

Boyle, B., Collins, M. H., Wang, Z., MacK, D., Griffiths, A., Sauer, C., Markowitz, J., Leleiko, N., Keljo, D., Rosh, J., Baker, S. S., Pfefferkorn, M., Heyman, M., Patel, A., Baldassano, R., Noe, J., Rufo, P., Kugathasan, S., Walters, T., Denson, L. & 1 others, Hyams, J., 2017, In : American Journal of Surgical Pathology. 41, 11, p. 1491-1498 8 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Inflammation
Eosinophils
Abscess
Endoscopy
2 Citations (Scopus)

The Incidence of Low Seroimmunity to Hepatitis B Virus in Children with Inflammatory Bowel Disease

Watts, A., Bennett, W. E., Molleston, J. P., Gupta, S. K., Croffie, J. M., Waseem, S., McFerron, B. A., Steiner, S. J., Kumar, S., Vanderpool, C. P., Hon, E. C., Bozic, M. A., Subbarao, G. C. & Pfefferkorn, M. D., Mar 22 2017, (Accepted/In press) In : Journal of Pediatric Gastroenterology and Nutrition.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Hepatitis B virus
Incidence
Hepatitis B Antibodies
Immunologic Factors
2015
35 Citations (Scopus)

Clinical Presentation and Five-Year Therapeutic Management of Very Early-Onset Inflammatory Bowel Disease in a Large North American Cohort

Oliva-Hemker, M., Hutfless, S., Al Kazzi, E. S., Lerer, T., Mack, D., Leleiko, N., Griffiths, A., Cabrera, J., Otley, A., Rick, J., Bousvaros, A., Rosh, J., Grossman, A., Saeed, S., Kay, M., Carvalho, R., Keljo, D., Pfefferkorn, M., Faubion, W., Kappelman, M. & 4 others, Sudel, B., Schaefer, M. E., Markowitz, J. & Hyams, J. S., Sep 1 2015, In : Journal of Pediatrics. 167, 3, p. 527-532.e3

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Therapeutics
North America
Registries
40 Citations (Scopus)

Concomitant Use of Immunomodulators Affects the Durability of Infliximab Therapy in Children With Crohn's Disease

Grossi, V., Lerer, T., Griffiths, A., LeLeiko, N., Cabrera, J., Otley, A., Rick, J., Mack, D., Bousvaros, A., Rosh, J., Grossman, A., Saeed, S., Kay, M., Boyle, B., Oliva-Hemker, M., Keljo, D., Pfefferkorn, M., Faubion, W., Kappelman, M. D., Sudel, B. & 2 others, Markowitz, J. & Hyams, J. S., Oct 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 10, p. 1748-1756 9 p., 54359.

Research output: Contribution to journalArticle

Immunologic Factors
Crohn Disease
Therapeutics
Infliximab
Methotrexate
23 Citations (Scopus)

Dissecting allele architecture of early onset IBD using high-density genotyping

Rabizadeh, S., Noe, J., Snapper, S., Otley, A., Cohen, S., Oliva-Hemker, M., Kirschner, B., Ashish, P., Ziring, D., Evans, J., Baker, S., Cutler, D. J., Zwick, M. E., Okou, D. T., Prahalad, S., Walters, T., Guthery, S. L., Dubinsky, M., Baldassano, R., Crandall, W. V. & 25 others, Rosh, J., Markowitz, J., Stephens, M., Kellermayer, R., Pfefferkorn, M., Heyman, M. B., LeLeiko, N., Mack, D., Moulton, D., Kappelman, M. D., Kumar, A., Prince, J., Bose, P., Mondal, K., Ramachandran, D., Bohnsack, J. F., Griffiths, A. M., Haberman, Y., Essers, J., Thompson, S. D., Aronow, B., Keljo, D. J., Hyams, J. S., Denson, L. A. & Kugathasan, S., Jun 22 2015, In : PLoS One. 10, 6, e0128074.

Research output: Contribution to journalArticle

inflammatory bowel disease
Inflammatory Bowel Diseases
genotyping
Alleles
alleles
5 Citations (Scopus)
Biliary Dyskinesia
Cholecystectomy
Gallbladder
Pathology
2014
116 Citations (Scopus)

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

Walters, T. D., Kim, M. O., Denson, L. A., Griffiths, A. M., Dubinsky, M., Markowitz, J., Baldassano, R., Crandall, W., Rosh, J., Pfefferkorn, M., Otley, A., Heyman, M. B., Leleiko, N., Baker, S., Guthery, S. L., Evans, J., Ziring, D., Kellermayer, R., Stephens, M., Mack, D. & 10 others, Oliva-Hemker, M., Patel, A. S., Kirschner, B., Moulton, D., Cohen, S., Kim, S., Liu, C., Essers, J., Kugathasan, S. & Hyams, J. S., Feb 2014, In : Gastroenterology. 146, 2, p. 383-391 9 p.

Research output: Contribution to journalArticle

Immunologic Factors
Secondary Prevention
Crohn Disease
Tumor Necrosis Factor-alpha
Therapeutics
9 Citations (Scopus)

Liver enzyme elevations within 3 months of diagnosis of inflammatory bowel disease and likelihood of liver disease

Goyal, A., Hyams, J. S., Lerer, T., Leleiko, N. S., Otley, A. R., Griffiths, A. M., Rosh, J. R., Cabrera, J. M., Oliva-Hemker, M. M., Mack, D. R., Rick, J. N., Pfefferkorn, M., Carvalho, R., Grossman, A. B., Hitch, M. C., Sudel, B., Kappelman, M. D., Saeed, S. A., Faubion, W. A., Schaefer, M. E. & 2 others, Markowitz, J. F. & Keljo, D. J., 2014, In : Journal of Pediatric Gastroenterology and Nutrition. 59, 3, p. 321-323 3 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Liver Diseases
Liver
Enzymes
Alanine Transaminase

NASPGHAN clinical report on the evaluation and treatment of pediatric patients with internal penetrating crohn disease: Intraabdominal abscess with and without fistula

Pfefferkorn, M., Marshalleck, F. E., Saeed, S. A., Splawski, J. B., Linden, B. C. & Weston, B. F., Apr 24 2014, Biologic Treatment of Pediatric Inflammatory Bowel Disease: A Decade of JPGN Contributions. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Crohn Disease
Abscess
Fistula
Pediatrics
Therapeutics
22 Citations (Scopus)

Retrospective cohort study of Methotrexate use in the treatment of pediatric Crohn's disease

Sunseri, W., Hyams, J. S., Lerer, T., Mack, D. R., Griffiths, A. M., Otley, A. R., Rosh, J. R., Carvalho, R., Grossman, A. B., Cabrera, J., Pfefferkorn, M., Rick, J., Leleiko, N. S., Hitch, M. C., Oliva-Hemker, M., Saeed, S. A., Kappelman, M., Markowitz, J. & Keljo, D. J., 2014, In : Inflammatory Bowel Diseases. 20, 8, p. 1341-1345 5 p.

Research output: Contribution to journalArticle

Methotrexate
Cohort Studies
Retrospective Studies
Immunologic Factors
Therapeutics
2013
13 Citations (Scopus)

NASPGHAN clinical report on the evaluation and treatment of pediatric patients with internal penetrating crohn disease: Intraabdominal abscess with and without fistula

Pfefferkorn, M., Marshalleck, F. E., Saeed, S. A., Splawski, J. B., Linden, B. C. & Weston, B. F., Sep 2013, In : Journal of Pediatric Gastroenterology and Nutrition. 57, 3, p. 394-400 7 p.

Research output: Contribution to journalArticle

Abdominal Abscess
Crohn Disease
Abscess
Fistula
Pediatrics
24 Citations (Scopus)

Outcome following aminosalicylate therapy in children newly diagnosed as having ulcerative colitis

Zeisler, B., Lerer, T., Markowitz, J., MacK, D., Griffiths, A., Bousvaros, A., Keljo, D., Rosh, J., Evans, J., Kappelman, M., Otley, A., Kay, M., Grossman, A., Saeed, S., Carvalho, R., Oliva-Hemker, M., Faubion, W., Sudel, B., Pfefferkorn, M., Ashai-Khan, F. & 2 others, Leleiko, N. & Hyams, J., Jan 2013, In : Journal of Pediatric Gastroenterology and Nutrition. 56, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

Mesalamine
Ulcerative Colitis
Adrenal Cortex Hormones
Physicians
Therapeutics
2012
4 Citations (Scopus)

Budesonide use in pediatric crohn disease

Otley, A., Leleiko, N., Langton, C., Lerer, T., MacK, D., Evans, J., Pfefferkorn, M., Carvalho, R., Rosh, J., Griffiths, A., Oliva-Hemker, M., Kay, M., Bousvaros, A., Stephens, M., Samson, C., Grossman, A., Keljo, D., Markowitz, J. & Hyams, J., Aug 2012, In : Journal of Pediatric Gastroenterology and Nutrition. 55, 2, p. 200-204 5 p.

Research output: Contribution to journalArticle

Budesonide
Ascending Colon
Crohn Disease
Ileum
Adrenal Cortex Hormones
88 Citations (Scopus)

Mathematical weighting of the pediatric Crohn's disease activity index (PCDAI) and comparison with its other short versions

Turner, D., Griffiths, A. M., Walters, T. D., Seah, T., Markowitz, J., Pfefferkorn, M., Keljo, D., Waxman, J., Otley, A., Leleiko, N. S., MacK, D., Hyams, J. & Levine, A., Jan 2012, In : Inflammatory Bowel Diseases. 18, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

Prostaglandins A
Pediatric Crohn's disease
Reproducibility of Results
Crohn Disease
Retrospective Studies
2011
2 Citations (Scopus)

Disorders of the Anorectum: Fissures, Fistulas, Prolapse, Hemorrhoids, Tags

Pfefferkorn, M. & Fitzgerald, J. F., 2011, Pediatric Gastrointestinal and Liver Disease. Elsevier Inc., p. 521-527 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hemorrhoids
Prolapse
Fistula
Human Growth Hormone
Crohn Disease
Growth Hormone
Fasting
Proteolysis
9 Citations (Scopus)

Esophageal pH monitoring with the BRAVO capsule: Experience in a single tertiary medical center

Cabrera, J., Davis, M., Horn, D., Pfefferkorn, M. & Croffie, J., Oct 2011, In : Journal of Pediatric Gastroenterology and Nutrition. 53, 4, p. 404-408 5 p.

Research output: Contribution to journalArticle

Esophageal pH Monitoring
Capsules
Digestive System Endoscopy
Tears
Equipment and Supplies
36 Citations (Scopus)

Exploring potential noninvasive biomarkers in eosinophilic esophagitis in children

Subbarao, G., Rosenman, M., Ohnuki, L., Georgelas, A., Davis, M., Fitzgerald, J. F., Molleston, J., Croffie, J., Pfefferkorn, M., Corkins, M. R., Lim, J. R., Steiner, S., Schaefer, E., Gleich, G. J. & Gupta, S., Dec 2011, In : Journal of Pediatric Gastroenterology and Nutrition. 53, 6, p. 651-658 8 p.

Research output: Contribution to journalArticle

Eosinophil-Derived Neurotoxin
Eosinophilic Esophagitis
Biomarkers
Serum
Interleukin-5
47 Citations (Scopus)

Outcome following thiopurine use in children with ulcerative colitis: A prospective multicenter registry study

Hyams, J. S., Lerer, T., MacK, D., Bousvaros, A., Griffiths, A., Rosh, J., Otley, A., Evans, J., Stephens, M., Kay, M., Keljo, D., Pfefferkorn, M., Saeed, S., Crandall, W., Michail, S., Kappelman, M. D., Grossman, A., Samson, C., Sudel, B., Oliva-Hemker, M. & 2 others, Leleiko, N. & Markowitz, J., May 2011, In : American Journal of Gastroenterology. 106, 5, p. 981-987 7 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Multicenter Studies
Registries
Adrenal Cortex Hormones
Mesalamine
10 Citations (Scopus)

Significance of esophageal Crohn disease in children

Ammoury, R. F. & Pfefferkorn, M., Mar 2011, In : Journal of Pediatric Gastroenterology and Nutrition. 52, 3, p. 291-294 4 p.

Research output: Contribution to journalArticle

Esophageal Diseases
Crohn Disease
Phenotype
Colonoscopy
Granuloma
2010
74 Citations (Scopus)

Appraisal of the pediatric crohn's disease activity index on four prospectively collected datasets: Recommended cutoff values and clinimetric properties

Turner, D., Griffiths, A. M., Walters, T. D., Seah, T., Markowitz, J., Pfefferkorn, M., Keljo, D., Otley, A., Leleiko, N. S., MacK, D., Hyams, J. & Levine, A., Sep 2010, In : American Journal of Gastroenterology. 105, 9, p. 2085-2092 8 p.

Research output: Contribution to journalArticle

Area Under Curve
Reproducibility of Results
Budesonide
Inflammatory Bowel Diseases
Registries
88 Citations (Scopus)

Extraintestinal manifestations of pediatric inflammatory bowel disease and their relation to disease type and severity

Dotson, J. L., Hyams, J. S., Markowitz, J., Leleiko, N. S., MacK, D. R., Evans, J. S., Pfefferkorn, M., Griffiths, A. M., Otley, A. R., Bousvaros, A., Kugathasan, S., Rosh, J. R., Keljo, D., Carvalho, R. S., Tomer, G., Mamula, P., Kay, M. H., Kerzner, B., Oliva-Hemker, M., Langton, C. R. & 1 others, Crandall, W., Aug 2010, In : Journal of Pediatric Gastroenterology and Nutrition. 51, 2, p. 140-145 6 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Pediatrics
Aphthous Stomatitis
Erythema Nodosum
Ulcerative Colitis
58 Citations (Scopus)

Factors that determine risk for surgery in pediatric patients with crohn's disease

Schaefer, M. E., Machan, J. T., Kawatu, D., Langton, C. R., Markowitz, J., Crandall, W., Mack, D. R., Evans, J. S., Pfefferkorn, M., Griffiths, A. M., Otley, A. R., Bousvaros, A., Kugathasan, S., Rosh, J. R., Keljo, D. J., Carvalho, R. S., Tomer, G., Mamula, P., Kay, M. H., Kerzner, B. & 5 others, Oliva-Hemker, M., Kappelman, M. D., Saeed, S. A., Hyams, J. S. & LeLeiko, N. S., Sep 2010, In : Clinical Gastroenterology and Hepatology. 8, 9

Research output: Contribution to journalArticle

Crohn Disease
Pediatrics
Immunologic Factors
Inflammatory Bowel Diseases
Ostomy
93 Citations (Scopus)

Outcome following infliximab therapy in children with ulcerative colitis

Hyams, J. S., Lerer, T., Griffiths, A., Pfefferkorn, M., Stephens, M., Evans, J., Otley, A., Carvalho, R., MacK, D., Bousvaros, A., Rosh, J., Grossman, A., Tomer, G., Kay, M., Crandall, W., Oliva-Hemker, M., Keljo, D., Leleiko, N. & Markowitz, J., Jun 2010, In : American Journal of Gastroenterology. 105, 6, p. 1430-1436 7 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Adrenal Cortex Hormones
Colectomy
Therapeutics
Registries
23 Citations (Scopus)

Utility of fecal lactoferrin in identifying crohn disease activity in children

Pfefferkorn, M., Boone, J. H., Nguyen, J. T., Juliar, B. E., Davis, M. A. & Parker, K. K., Oct 2010, In : Journal of Pediatric Gastroenterology and Nutrition. 51, 4, p. 425-428 4 p.

Research output: Contribution to journalArticle

Lactoferrin
Crohn Disease
Blood Sedimentation
Pediatrics
Biomarkers
2009
64 Citations (Scopus)

Age of diagnosis influences serologic responses in children with Crohn's disease: A possible clue to etiology?

Markowirz, J., Kugathasan, S., Dubinsky, M., Mei, L., Crandall, W., LeLeiko, N., Oliva-Hemker, M., Rosh, J., Evans, J., Mack, D., Otley, A., Pfefferkorn, M., Bahar, R., Vasiliauskas, E., Wahbeh, G., Silber, G., Quiros, J. A., Wrobel, I., Nebel, J., Landers, C. & 4 others, Picornell, Y., Targan, S., Lerer, T. & Hyams, J., 2009, In : Inflammatory Bowel Diseases. 15, 5, p. 714-719 6 p.

Research output: Contribution to journalArticle

Crohn Disease
Immunoglobulin A
Inflammatory Bowel Diseases
Age Groups
Immunoglobulin G
132 Citations (Scopus)

Appraisal of the Pediatric Ulcerative Colitis Activity Index (PUCAI)

Turner, D., Hyams, J., Markowitz, J., Lerer, T., Mack, D. R., Evans, J., Pfefferkorn, M., Rosh, J., Kay, M., Crandall, W., Keljo, D., Otley, A. R., Kugathasan, S., Carvalho, R., Oliva-Hemker, M., Langton, C., Mamula, P., Bousvaros, A., LeLeiko, N. & Griffiths, A. M., 2009, In : Inflammatory Bowel Diseases. 15, 8, p. 1218-1223 6 p.

Research output: Contribution to journalArticle

Confidence Intervals
Area Under Curve
Pediatric ulcerative colitis
Ulcerative Colitis
Psychometrics
70 Citations (Scopus)

Course and treatment of perianal disease in children newly diagnosed with Crohn's disease

Keljo, D. J., Markowitz, J., Langton, C., Lerer, T., Bousvaros, A., Carvalho, R., Crandall, W., Evans, J., Griffiths, A., Kay, M., Kugathasan, S., LeLeiko, N., Mack, D., Mamula, P., Moyer, M. S., Oliva-Hemker, M., Otley, A., Pfefferkorn, M., Rosh, J. & Hyams, J. S., 2009, In : Inflammatory Bowel Diseases. 15, 3, p. 383-387 5 p.

Research output: Contribution to journalArticle

Crohn Disease
Therapeutics
Abscess
Fistula
Pediatrics
4 Citations (Scopus)
Colectomy
Colitis
Crohn Disease
Pediatrics
Ulcerative Colitis
14 Citations (Scopus)

Functional gastrointestinal disorders: Past and present

Ammoury, R. F., Pfefferkorn, M. & Croffie, J., 2009, In : World Journal of Pediatrics. 5, 2, p. 103-112 10 p.

Research output: Contribution to journalArticle

Gastrointestinal Diseases
Chronic Pain
Abdominal Pain
Psychology
Pediatrics
100 Citations (Scopus)

Growth abnormalities persist in newly diagnosed children with crohn disease despite current treatment paradigms

Pfefferkorn, M., Burke, G., Griffiths, A., Markowitz, J., Rosh, J., MacK, D., Otley, A., Kugathasan, S., Evans, J., Bousvaros, A., Moyer, M. S., Wyllie, R., Oliva-Hemker, M., Carvalho, R., Crandall, W., Keljo, D., Walters, T. D., Leleiko, N. & Hyams, J., Feb 2009, In : Journal of Pediatric Gastroenterology and Nutrition. 48, 2, p. 168-174 7 p.

Research output: Contribution to journalArticle

Crohn Disease
Immunologic Factors
Growth
Adrenal Cortex Hormones
Therapeutics
132 Citations (Scopus)

Long-term outcome of maintenance infliximab therapy in children with Crohn's disease

Hyams, J. S., Lerer, T., Griffiths, A., Pfefferkorn, M., Kugathasan, S., Evans, J., Otley, A., Carvalho, R., Mack, D., Bousvaros, A., Rosh, J., Mamula, P., Kay, M., Crandall, W., Oliva-Hemker, M., Keljo, D., LeLeiko, N. & Markowitz, J., 2009, In : Inflammatory Bowel Diseases. 15, 6, p. 816-822 7 p.

Research output: Contribution to journalArticle

Crohn Disease
Maintenance
Adrenal Cortex Hormones
Therapeutics
Infliximab
93 Citations (Scopus)

Retrospective evaluation of the safety and effect of adalimumab therapy (RESEAT) in pediatric crohns disease

Rosh, J. R., Lerer, T., Markowitz, J., Goli, S. R., Mamula, P., Noe, J. D., Pfefferkorn, M., Kelleher, K. T., Griffiths, A. M., Kugathasan, S., Keljo, D., Oliva-Hemker, M., Crandall, W., Carvalho, R. S., MacK, D. R. & Hyams, J. S., Dec 2009, In : American Journal of Gastroenterology. 104, 12, p. 3042-3049 8 p.

Research output: Contribution to journalArticle

Safety
Therapeutics
Crohn Disease
Pediatric Crohn's disease
Adalimumab
43 Citations (Scopus)

Variation in care in pediatric crohn disease

Colletti, R. B., Baldassano, R. N., Milov, D. E., Margolis, P. A., Bousvaros, A., Crandall, W. V., Crissinger, K. D., D'Amico, M. A., Day, A. S., Denson, L. A., Dubinsky, M., Ebach, D. R., Hoffenberg, E. J., Kader, H. A., Keljo, D. J., Leibowitz, I. H., Mamula, P., Pfefferkorn, M. & Qureshi, M. A., Sep 2009, In : Journal of Pediatric Gastroenterology and Nutrition. 49, 3, p. 297-303 7 p.

Research output: Contribution to journalArticle

thiopurine methyltransferase
Crohn Disease
Pediatrics
Therapeutics
Blood Cell Count
2008
Abdominal Radiography
Proctitis
Gastrointestinal Endoscopy
Appendicitis
Inflammation
9 Citations (Scopus)

Carbohydrate and lipid metabolism following infliximab therapy in pediatric Crohn's disease

Steiner, S., Pfefferkorn, M., Fitzgerald, J. F. & Denne, S., Dec 2008, In : Pediatric Research. 64, 6, p. 673-676 4 p.

Research output: Contribution to journalArticle

Carbohydrate Metabolism
Lipid Metabolism
Crohn Disease
Insulin Resistance
Energy Metabolism
270 Citations (Scopus)

Comparison of Oral Prednisone and Topical Fluticasone in the Treatment of Eosinophilic Esophagitis: A Randomized Trial in Children

Schaefer, E. T., Fitzgerald, J. F., Molleston, J., Croffie, J., Pfefferkorn, M., Corkins, M. R., Lim, J. D., Steiner, S. & Gupta, S., Feb 2008, In : Clinical Gastroenterology and Hepatology. 6, 2, p. 165-173 9 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Prednisone
Recurrence
Therapeutics
Kaplan-Meier Estimate
94 Citations (Scopus)

Effect of early immunomodulator use in moderate to severe pediatric Crohn disease

Punati, J., Markowitz, J., Lerer, T., Hyams, J., Kugathasan, S., Griffiths, A., Otley, A., Rosh, J., Pfefferkorn, M., Mack, D., Evans, J., Bousvaros, A., Susan Moyer, M., Wyllie, R., Oliva-Hemker, M., Mezoff, A., Leleiko, N., Keljo, D. & Crandall, W., Jul 2008, In : Inflammatory Bowel Diseases. 14, 7, p. 949-954 6 p.

Research output: Contribution to journalArticle

Immunologic Factors
Adrenal Cortex Hormones
Crohn Disease
Hospitalization
6-Mercaptopurine
4 Citations (Scopus)
Parenteral Nutrition
Fibrinogen
Albumins
Parenteral Infusions
Fasting