Mark Soonpaa

  • 8338 Citations
  • 33 h-Index
1992 …2018

Research output per year

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Publications

  • 8338 Citations
  • 33 h-Index
  • 43 Article
  • 3 Review article
  • 2 Letter
  • 1 Chapter
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Article
2018

Electrical coupling between ventricular myocytes and myofibroblasts in the infarcted mouse heart

Rubart, M., Tao, W., Lu, X. L., Conway, S. J., Reuter, S. P., Lin, S. F. & Soonpaa, M. H., Mar 1 2018, In : Cardiovascular research. 114, 3, p. 389-400 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish

González-Rosa, J. M., Sharpe, M., Field, D., Soonpaa, M. H., Field, L. J., Burns, C. E. & Burns, C. G., Feb 26 2018, In : Developmental Cell. 44, 4, p. 433-446.e7

Research output: Contribution to journalArticle

71 Scopus citations
2015

Cardiac engraftment of genetically-selected parthenogenetic stem cell-derived cardiomyocytes

Yang, T., Rubart, M., Soonpaa, M. H., Didié, M., Christalla, P., Zimmermann, W. H. & Field, L. J., Jun 25 2015, In : PLoS ONE. 10, 6, e0131511.

Research output: Contribution to journalArticle

3 Scopus citations
2014

In situ three-dimensional reconstruction of mouse heart sympathetic innervation by two-photon excitation fluorescence imaging

Freeman, K., Tao, W., Sun, H., Soonpaa, M. H. & Rubart, M., Jan 15 2014, In : Journal of Neuroscience Methods. 221, p. 48-61 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice

Reuter, S., Soonpaa, M. H., Firulli, A. B., Chang, A. N. & Field, L. J., Dec 29 2014, In : PloS one. 9, 12, e115871.

Research output: Contribution to journalArticle

36 Scopus citations
2013

Parthenogenetic stem cells for tissue-engineered heart repair

Didié, M., Christalla, P., Rubart, M., Muppala, V., Döker, S., Unsöld, B., El-Armouche, A., Rau, T., Eschenhagen, T., Schwoerer, A. P., Ehmke, H., Schumacher, U., Fuchs, S., Lange, C., Becker, A., Tao, W., Scherschel, J. A., Soonpaa, M. H., Yang, T., Lin, Q. & 11 others, Zenke, M., Han, D. W., Schöler, H. R., Rudolph, C., Steinemann, D., Schlegelberger, B., Kattman, S., Witty, A., Keller, G., Field, L. J. & Zimmermann, W. H., Mar 1 2013, In : Journal of Clinical Investigation. 123, 3, p. 1285-1298 14 p.

Research output: Contribution to journalArticle

72 Scopus citations
2012

Functional screening of intracardiac cell transplants using two-photon fluorescence microscopy

Tao, W., Soonpaa, M. H., Field, L. J., Chen, P. S., Firulli, A. B., Shou, W. & Rubart, M., Aug 1 2012, In : Pediatric Cardiology. 33, 6, p. 929-937 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
21 Scopus citations
2010

Cardiomyogenic potential of C-kit+-expressing cells derived from neonatal and adult mouse hearts

Zaruba, M. M., Soonpaa, M., Reuter, S. & Field, L. J., May 11 2010, In : Circulation. 121, 18, p. 1992-2000 9 p.

Research output: Contribution to journalArticle

167 Scopus citations

Limitations of conventional approaches to identify myocyte nuclei in histologic sections of the heart

Ang, K. L., Shenje, L. T., Reuter, S., Soonpaa, M. H., Rubart, M., Field, L. J. & Galiñanes, M., Jun 2010, In : American Journal of Physiology - Cell Physiology. 298, 6, p. C1603-C1609

Research output: Contribution to journalArticle

31 Scopus citations
2009

Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathway

Zhu, W., Soonpaa, M. H., Chen, H., Shen, W., Payne, R. M., Liechty, E. A., Caldwell, R. L., Shou, W. & Field, L. J., Jan 13 2009, In : Circulation. 119, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

129 Scopus citations
2008
48 Scopus citations

Cardiomyocyte cell cycle activation improves cardiac function after myocardial infarction

Hassink, R. J., Pasumarthi, K. B., Nakajima, H., Rubart, M., Soonpaa, M. H., De La Rivière, A. B., Doevendans, P. A. & Field, L. J., Apr 2008, In : Cardiovascular research. 78, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

Yang, L., Soonpaa, M. H., Adler, E. D., Roepke, T. K., Kattman, S. J., Kennedy, M., Henckaerts, E., Bonham, K., Abbott, G. W., Linden, R. M., Field, L. J. & Keller, G. M., May 22 2008, In : Nature. 453, 7194, p. 524-528 5 p.

Research output: Contribution to journalArticle

1013 Scopus citations

Lineage tracing of cardiac explant derived cells

Shenje, L. T., Field, L. J., Pritchard, C. A., Guerin, C. J., Rubart, M., Soonpaa, M. H., Ang, K. L. & Galiñanes, M., Apr 16 2008, In : PloS one. 3, 4, e1929.

Research output: Contribution to journalArticle

33 Scopus citations
2006

Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth

Chen, H., Yong, W., Ren, S., Shen, W., He, Y., Cox, K. A., Zhu, W., Li, W., Soonpaa, M., Payne, R. M., Franco, D., Field, L. J., Rosen, V., Wang, Y. & Shou, W., Sep 15 2006, In : Journal of Biological Chemistry. 281, 37, p. 27481-27491 11 p.

Research output: Contribution to journalArticle

41 Scopus citations
2005

Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice

Pasumarthi, K. B. S., Nakajima, H., Nakajima, H. O., Soonpaa, M. H. & Field, L. J., Jan 21 2005, In : Circulation research. 96, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

234 Scopus citations
2004

Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

Murry, C. E., Soonpaa, M. H., Reinecke, H., Nakajima, H., Nakajima, H. O., Rubart, M., Pasumarthi, K. B. S., Virag, J. I., Bartelmez, S. H., Poppa, V., Bradford, G., Dowell, J. D., Williams, D. A. & Field, L. J., Apr 8 2004, In : Nature. 428, 6983, p. 664-668 5 p.

Research output: Contribution to journalArticle

1816 Scopus citations
141 Scopus citations
2003

Physiological coupling of donor and host cardiomyocytes after cellular transplantation

Rubart, M., Pasumarthi, K. B. S., Nakajima, H., Soonpaa, M. H., Nakajima, H. O. & Field, L. J., Jun 13 2003, In : Circulation research. 92, 11, p. 1217-1224 8 p.

Research output: Contribution to journalArticle

178 Scopus citations
2001

Functional abrogation of p53 is required for T-Ag induced proliferation in cardiomyocytes

Huh, N. E., Pasumarthi, K. B. S., Soonpaa, M. H., Jing, S., Patton, B. & Field, L. J., Jan 1 2001, In : Journal of Molecular and Cellular Cardiology. 33, 8, p. 1405-1419 15 p.

Research output: Contribution to journalArticle

17 Scopus citations
2000

Heritable lympho-epithelial thymoma resulting from a transgene insertional mutation

Nakajima, H., Nakajima, H. O., Soonpaa, M. H., Jing, S. & Field, L. J., Jan 6 2000, In : Oncogene. 19, 1, p. 32-38 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
1997
222 Scopus citations

Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice

Soonpaa, M. H., Koh, G. Y., Pajak, L., Jing, S., Wang, H., Franklin, M. T., Kim, K. K. & Field, L. J., Jun 1 1997, In : Journal of Clinical Investigation. 99, 11, p. 2644-2654 11 p.

Research output: Contribution to journalArticle

Open Access
185 Scopus citations

Sustained cardiomyocyte DNA synthesis in whole embryo cultures lacking the TSC2 gene product

Pajak, L., Jin, F., Xiao, G. H., Soonpaa, M. H., Field, L. J. & Yeung, R. S., Oct 13 1997, In : American Journal of Physiology - Heart and Circulatory Physiology. 273, 3 42-3, p. H1619-H1627

Research output: Contribution to journalArticle

21 Scopus citations
1996

Cardiomyocyte DNA synthesis and binucleation during murine development

Soonpaa, M. H., Kim, K. K., Pajak, L., Franklin, M. & Field, L. J., Nov 1 1996, In : American Journal of Physiology - Heart and Circulatory Physiology. 271, 5 40-5, p. H2183-H2189

Research output: Contribution to journalArticle

443 Scopus citations

Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts

Klug, M. G., Soonpaa, M. H., Koh, G. Y. & Field, L. J., Jul 1 1996, In : Journal of Clinical Investigation. 98, 1, p. 216-224 9 p.

Research output: Contribution to journalArticle

Open Access
923 Scopus citations
1995

Developmental expression of p107 mrna and evidence for alternative splicing of the p107 (RBL1) gene product

Kim, K. K., Soonpaa, M. H., Wang, H. & Field, L. J., Aug 10 1995, In : Genomics. 28, 3, p. 520-529 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
54 Scopus citations

Length dependence of Ca2+ sensitivity of tension in mouse cardiac myocytes expressing skeletal troponin C.

McDonald, K. S., Field, L. J., Parmacek, M. S., Soonpaa, M., Leiden, J. M. & Moss, R. L., Feb 15 1995, In : The Journal of Physiology. 483, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Overexpression of NGF within the Heart of Transgenic Mice Causes Hyperinnervation, Cardiac Enlargement, and Hyperplasia of Ectopic Cells

Hassankhani, A., Steinhelper, M. E., Soonpaa, M. H., Katz, E. B., Taylor, D. A., Andrade-Rozental, A., Factor, S. M., Steinberg, J. J., Field, L. J. & Federoff, H. J., May 1995, In : Developmental Biology. 169, 1, p. 309-321 13 p.

Research output: Contribution to journalArticle

111 Scopus citations

Potential Approaches for Myocardial Regeneration

SOONPAA, MARK. H., DAUD, ADIL. I., KOH, GOU. YOUNG., KLUG, MICHAEL. G., KIM, KYUNG. KEUN., WANG, HE. & FIELD, LOREN. J., Mar 1995, In : Annals of the New York Academy of Sciences. 752, 1, p. 446-454 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Stable fetal cardiomyocyte grafts in the hearts of dystrophic mice and dogs

Koh, G. Y., Soonpaa, M. H., Klug, M. G., Pride, H. P., Cooper, B. J., Zipes, D. P. & Field, L. J., Oct 1995, In : Journal of Clinical Investigation. 96, 4, p. 2034-2042 9 p.

Research output: Contribution to journalArticle

Open Access
163 Scopus citations

Stimulation of Proliferative Events in the Adult Amphibian Cardiac Myocyte

OBERPRILLER, JOHN. O., OBERPRILLER, JEAN. C., MATZ, DONALD. G. & SOONPAA, MARK. H., Mar 1995, In : Annals of the New York Academy of Sciences. 752, 1, p. 30-46 17 p.

Research output: Contribution to journalArticle

49 Scopus citations

Strategies for Myocardial Repair

KOH, GOU. YOUNG., SOONPAA, MARK. H., KLUG, MICHAEL. G. & FIELD, LOREN. J., Aug 1995, In : Journal of interventional cardiology. 8, 4, p. 387-393 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Targeted expression of transforming growth factor-β1 in intracardiac grafts promotes vascular endothelial cell DNA synthesis

Koh, G. Y., Kim, S. J., Klug, M. G., Park, K., Soonpaa, M. H. & Field, L. J., Jan 1995, In : Journal of Clinical Investigation. 95, 1, p. 114-121 8 p.

Research output: Contribution to journalArticle

Open Access
86 Scopus citations
1994
86 Scopus citations

Factors altering DNA synthesis in the cardiac myocyte of the adult newt, Notophthalmus viridescens

Soonpaa, M. H., Oberpriller, J. O. & Oberpriller, J. C., Feb 1 1994, In : Cell & Tissue Research. 275, 2, p. 377-382 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium

Soonpaa, M. H., Koh, G. Y., Klug, M. G. & Field, L. J., Jan 1 1994, In : Science. 264, 5155, p. 98-101 4 p.

Research output: Contribution to journalArticle

490 Scopus citations

Tumor suppressor gene expression during normal and pathologic myocardial growth

Kyung Keun Kim, K. K., Soonpaa, M. H., Daud, A. I., Gou Young Koh, Y. K., Jin Sang Kim, S. K. & Field, L. J., 1994, In : Journal of Biological Chemistry. 269, 36, p. 22607-22613 7 p.

Research output: Contribution to journalArticle

67 Scopus citations
1993

Differentiation and long-term survival of C2C12 myoblast grafts in heart

Koh, G. Y., Klug, M. G., Soonpaa, M. H. & Field, L. J., Sep 1993, In : Journal of Clinical Investigation. 92, 3, p. 1548-1554 7 p.

Research output: Contribution to journalArticle

Open Access
226 Scopus citations

Long-term survival of AT-1 cardiomyocyte grafts in syngeneic myocardium

Gou Young Koh, Y. K., Soonpaa, M. H., Klug, M. G. & Field, L. J., Jan 1 1993, In : American Journal of Physiology - Heart and Circulatory Physiology. 264, 5 33-5, p. H1727-H1733

Research output: Contribution to journalArticle

112 Scopus citations
1992

Stimulation of DNA synthesis by PDGF in the newt cardiac myocyte

Soonpaa, M. H., Oberpriller, J. O. & Oberpriller, J. C., Sep 1992, In : Journal of Molecular and Cellular Cardiology. 24, 9, p. 1039-1046 8 p.

Research output: Contribution to journalArticle

17 Scopus citations