Melissa Fishel

  • 1764 Citations
  • 23 h-Index
20022019
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  • 25 Similar Profiles
DNA Repair Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
DNA-(Apurinic or Apyrimidinic Site) Lyase Medicine & Life Sciences
Oxidation-Reduction Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Repair Chemical Compounds
Proteins Medicine & Life Sciences

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NIH Grants 2007 2017

Pancreatic Neoplasms
Oxidation-Reduction
gemcitabine
Neoplasms
Adenocarcinoma
gemcitabine
temozolomide
Pancreatic Neoplasms
DNA Repair
DNA

Publications 2002 2019

  • 1764 Citations
  • 23 h-Index
  • 46 Article
  • 3 Chapter
  • 1 Book

Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer

Shouksmith, A. E., Shah, F., Grimard, M. L., Gawel, J. M., Raouf, Y. S., Geletu, M., Berger-Becvar, A., De Araujo, E. D., Luchman, H. A., Heaton, W. L., Bakhshinyan, D., Adile, A. A., Venugopal, C., O'Hare, T., Deininger, M. W., Singh, S. K., Konieczny, S. F., Weiss, S., Fishel, M. & Gunning, P. T., Mar 14 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2651-2665 15 p.

Research output: Contribution to journalArticle

Hydroxamic Acids
Histone Deacetylase Inhibitors
Pancreatic Neoplasms
Adenocarcinoma
Survival
2 Citations (Scopus)

APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells

McIlwain, D. W., Fishel, M., Boos, A., Kelley, M. & Jerde, T., Jan 1 2018, In : Oncotarget. 9, 13, p. 10962-10977 16 p.

Research output: Contribution to journalArticle

Endonucleases
Cell Cycle Checkpoints
Oxidation-Reduction
Prostatic Neoplasms
Proteins
1 Citation (Scopus)

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

Logsdon, D. P., Shah, F., Carta, F., Supuran, C. T., Kamocka, M., Jacobsen, M. H., Sandusky, G., Kelley, M. & Fishel, M., Dec 1 2018, In : Scientific Reports. 8, 1, 13759.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Cell Survival
Adenocarcinoma
Oxidation-Reduction
Neoplasms

Development of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening

Puls, T. J., Tan, X., Husain, M., Whittington, C. F., Fishel, M. & Voytik-Harbin, S. L., Dec 1 2018, In : Scientific Reports. 8, 1, 13039.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
Neoplasms
Pancreatic Neoplasms
Phenotype
Collagen Type I
5 Citations (Scopus)

Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition

Marisol Herrera-Perez, R., Voytik-Harbin, S. L., Sarkaria, J. N., Pollok, K., Fishel, M. & Rickus, J. L., Mar 1 2018, In : PLoS One. 13, 3, e0194183.

Research output: Contribution to journalArticle

Tumor Microenvironment
stromal cells
Glioblastoma
Stromal Cells
Tumors