Michael Eadon

  • 472 Citations
  • 12 h-Index
20052020

Research output per year

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Publications

  • 472 Citations
  • 12 h-Index
  • 28 Article
  • 5 Review article
  • 2 Chapter
2020

Implementation of a renal precision medicine program: Clinician attitudes and acceptance

Spiech, K. M., Tripathy, P. R., Woodcock, A. M., Sheth, N. A., Collins, K. S., Kannegolla, K., Sinha, A. D., Sharfuddin, A. A., Pratt, V. M., Khalid, M., Hains, D. S., Moe, S. M., Skaar, T. C., Moorthi, R. N. & Eadon, M. T., Apr 2020, In : Life. 10, 4, 32.

Research output: Contribution to journalArticle

Open Access

Increasing Nephrologist Awareness of Symptom Burden in Older Hospitalized End-Stage Renal Disease Patients

Jawed, A., Moe, S. M., Moorthi, R. N., Torke, A. M. & Eadon, M. T., Jan 1 2020, In : American journal of nephrology. 51, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Interindividual Variability in Lymphocyte Stimulation and Transcriptomic Response Predicts Mycophenolic Acid Sensitivity in Healthy Volunteers

Collins, K. S., Cheng, Y. H., Ferreira, R. M., Gao, H., Dollins, M. D., Janosevic, D., Khan, N. A., White, C., Dagher, P. C. & Eadon, M. T., Jan 1 2020, (Accepted/In press) In : Clinical and translational science.

Research output: Contribution to journalArticle

Open Access

Kidney Histopathology and Prediction of Kidney Failure: A Retrospective Cohort Study

Eadon, M. T., Schwantes-An, T. H., Phillips, C. L., Roberts, A. R., Greene, C. V., Hallab, A., Hart, K. J., Lipp, S. N., Perez-Ledezma, C., Omar, K. O., Kelly, K. J., Moe, S. M., Dagher, P. C., El-Achkar, T. M. & Moorthi, R. N., Jan 1 2020, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Open Access
2019

Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy

Collins, K. S., Pratt, V. M., Stansberry, W. M., Medeiros, E. B., Kannegolla, K., Swart, M., Skaar, T. C., Chapman, A. B., Decker, B. S., Moorthi, R. N. & Eadon, M. T., Jan 1 2019, In : Pharmacogenetics and Genomics. 29, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bacterial sepsis triggers an antiviral response that causes translation shutdown

Hato, T., Maier, B., Syed, F., Myslinski, J., Zollman, A., Plotkin, Z., Eadon, M. T. & Dagher, P. C., Jan 2 2019, In : Journal of Clinical Investigation. 129, 1, CI123284.

Research output: Contribution to journalArticle

7 Scopus citations

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Fulton, C. R., Zang, Y., Desta, Z., Rosenman, M. B., Holmes, A. M., Decker, B. S., Zhang, Y., T Callaghan, J., Pratt, V. M., Levy, K. D., Gufford, B. T., Dexter, P. R., Skaar, T. C. & Eadon, M. T., Apr 1 2019, In : Pharmacogenomics. 20, 6, p. 397-408 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access

Practical Considerations of Renal Biopsies in Critical Care Patients

Modi, J. R., Liapis, H., Molitoris, B. A. & Eadon, M. T., Jan 1 2019, Critical Care Nephrology: Third Edition. Elsevier Inc., p. 167-173.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

RegSNPs-intron: A computational framework for predicting pathogenic impact of intronic single nucleotide variants

Lin, H., Hargreaves, K. A., Li, R., Reiter, J. L., Wang, Y., Mort, M., Cooper, D. N., Zhou, Y., Zhang, C., Eadon, M. T., Dolan, M. E., Ipe, J., Skaar, T. C. & Liu, Y., Nov 28 2019, In : Genome biology. 20, 1, 254.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Pharmacogenetics and Practice: Tailoring Prescribing for Safety and Effectiveness

Fulton, C. R., Swart, M., De Luca, T., Liu, S. N., Collins, K. S., Desta, Z., Gufford, B. T. & Eadon, M. T., Nov 1 2018, In : Journal for Nurse Practitioners. 14, 10, p. 697-704.e1

Research output: Contribution to journalArticle

1 Scopus citations

Pharmacogenomic studies of hypertension: Paving the way for personalized antihypertensive treatment

Eadon, M. T., Kanuri, S. H. & Chapman, A. B., Jan 3 2018, In : Expert Review of Precision Medicine and Drug Development. 3, 1, p. 33-47 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Quantitative large-scale three-dimensional imaging of human kidney biopsies: A bridge to precision medicine in kidney disease

Winfree, S., Dagher, P. C., Dunn, K. W., Eadon, M. T., Ferkowicz, M., Barwinska, D., Kelly, K. J., Sutton, T. A. & El-Achkar, T. M., Sep 1 2018, In : Nephron. 140, 2, p. 134-139 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

Gufford, B. T., Robarge, J. D., Eadon, M. T., Gao, H., Lin, H., Liu, Y., Desta, Z. & Skaar, T. C., Apr 2018, In : Pharmacology Research and Perspectives. 6, 2, e00386.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Clinical and educational impact of pharmacogenomics testing: A case series from the INGENIOUS trial

Pierson, R. C., Gufford, B. T., Desta, Z. & Eadon, M. T., Jun 2017, In : Pharmacogenomics. 18, 9, p. 835-841 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genetic variants contributing to colistin cytotoxicity: Identification of TGIF1 and HOXD10 using a population genomics approach

Eadon, M. T., Hause, R. J., Stark, A. L., Cheng, Y. H., Wheeler, H. E., Burgess, K. S., Benson, E. A., Cunningham, P. N., Bacallao, R. L., Dagher, P. C., Skaar, T. C. & Dolan, M. E., Mar 18 2017, In : International journal of molecular sciences. 18, 3, 661.

Research output: Contribution to journalArticle

Healthcare outcomes in undocumented immigrants undergoing two emergency dialysis approaches

Sher, S. J., Aftab, W., Moorthi, R. N., Moe, S. M., Weaver, C. S., Messina, F. C., Martinez-Hoover, N. M., Anderson, M. D. & Eadon, M. T., Jan 1 2017, In : Clinical Nephrology. 88, 4, p. 181-189 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications

Winfree, S., Ferkowicz, M. J., Dagher, P. C., Kelly, K. J., Eadon, M. T., Sutton, T. A., Markel, T. A., Yoder, M. C., Dunn, K. W. & El-Achkar, T. M., Nov 2017, In : Translational Research. 189, p. 1-12 12 p.

Research output: Contribution to journalReview article

6 Scopus citations

Lessons Learned When Introducing Pharmacogenomic Panel Testing into Clinical Practice

Rosenman, M. B., Decker, B., Levy, K. D., Holmes, A. M., Pratt, V. M. & Eadon, M. T., Jan 1 2017, In : Value in Health. 20, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Quantitative three-dimensional tissue cytometry to study kidney tissue and resident immune cells

Winfree, S., Khan, S., Micanovic, R., Eadon, M., Kelly, K., Sutton, T., Phillips, C., Dunn, K. & Ashkar (El-Achkar), T., Jul 1 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2108-2118 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

A Physiologic Approach to the Pharmacogenomics of Hypertension

Eadon, M. T. & Chapman, A. B., Mar 1 2016, In : Advances in Chronic Kidney Disease. 23, 2, p. 91-105 15 p.

Research output: Contribution to journalReview article

5 Scopus citations

Implementation of a pharmacogenomics consult service to support the INGENIOUS trial

Eadon, M. T., Desta, Z., Levy, K. D., Decker, B. S., Pierson, R. C., Pratt, V. M., Callaghan, J. T., Rosenman, M. B., Carpenter, J. S., Holmes, A. M., McDonald, C. A., Benson, E. A., Patil, A. S., Vuppalanchi, R., Gufford, B. T., Dave, N., Robarge, J. D., Hyder, M. A., Haas, D. M., Kreutz, R. P. & 3 others, Dexter, P. R., Skaar, T. C. & Flockhart, D. A., Jul 1 2016, In : Clinical Pharmacology and Therapeutics. 100, 1, p. 63-66 4 p.

Research output: Contribution to journalReview article

21 Scopus citations

Rifampin regulation of drug transporters gene expression and the association of microRNAs in human hepatocytes

Benson, E., Eadon, M., Desta, Z., Liu, Y., Lin, H., Burgess, K. S., Segar, M. W., Gaedigk, A. & Skaar, T., Apr 26 2016, In : Frontiers in Pharmacology. 7, APR, 111.

Research output: Contribution to journalArticle

20 Scopus citations
2015
1 Scopus citations
2014

TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis

Xu, C., Chang, A., Hack, B. K., Eadon, M. T., Alper, S. L. & Cunningham, P. N., Jan 2014, In : Kidney international. 85, 1, p. 72-81 10 p.

Research output: Contribution to journalArticle

107 Scopus citations

Transcriptional profiling reveals that C5a alters microRNA in brain endothelial cells

Eadon, M. T., Jacob, A., Cunningham, P. N., Quigg, R. J., Garcia, J. G. N. & Alexander, J. J., Jan 1 2014, In : Immunology. 143, 3, p. 363-373 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Cell cycle arrest in a model of colistin nephrotoxicity

Eadon, M. T., Hack, B. K., Alexander, J. J., Xu, C., Dolan, M. E. & Cunningham, P. N., Oct 1 2013, In : Physiological Genomics. 45, 19, p. 877-888 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice

Jacob, A., Chaves, L., Eadon, M. T., Chang, A., Quigg, R. J. & Alexander, J. J., Jul 1 2013, In : Immunology. 139, 3, p. 328-337 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Genetic and epigenetic variants contributing to clofarabine cytotoxicity

Eadon, M. T., Wheeler, H. E., Stark, A. L., Zhang, X., Moen, E. L., Delaney, S. M., Im, H. K., Cunningham, P. N., Zhang, W. & Dolan, E. E., Oct 1 2013, In : Human molecular genetics. 22, 19, p. 4007-4020 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

International transporter consortium commentary on clinically important transporter polymorphisms

Giacomini, K. M., Balimane, P. V., Cho, S. K., Eadon, M., Edeki, T., Hillgren, K. M., Huang, S. M., Sugiyama, Y., Weitz, D., Wen, Y., Xia, C. Q., Yee, S. W., Zimdahl, H. & Niemi, M., Jul 1 2013, In : Clinical Pharmacology and Therapeutics. 94, 1, p. 23-26 4 p.

Research output: Contribution to journalReview article

98 Scopus citations
2012

Autologous creatinine clearance in a case of necrotizing fasciitis and anuria

Eadon, M. T. & Koyner, J. L., Mar 1 2012, In : American journal of nephrology. 35, 3, p. 225-229 5 p.

Research output: Contribution to journalArticle

Endotoxemia alters tight junction gene and protein expression in the kidney

Eadon, M. T., Hack, B. K., Xu, C., Ko, B., Gary Toback, F. & Cunningham, P. N., Sep 15 2012, In : American Journal of Physiology - Renal Physiology. 303, 6, p. F821-F830

Research output: Contribution to journalArticle

29 Scopus citations

The history of isolated ultrafiltration

Kohn, O. F., Eadon, M. T., Kjellstrand, C. M. & Ing, T. S., Jan 1 2012, Dialysis: History, Development and Promise. World Scientific Publishing Co., p. 341-348 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Whole blood viscosity: Effect of hemodialysis treatment and implications for access patency and vascular disease

Dhar, P., Eadon, M., Hallak, P., Munoz, R. A. & Hammes, M., Sep 10 2012, In : Clinical Hemorheology and Microcirculation. 51, 4, p. 265-275 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2005

Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion

Mkrtchyan, S. R., Markosyan, R. M., Eadon, M. T., Moore, J. P., Melikyan, G. B. & Cohen, F. S., Sep 1 2005, In : Journal of virology. 79, 17, p. 11161-11169 9 p.

Research output: Contribution to journalArticle

45 Scopus citations