Michele Yip-Schneider

  • 2162 Citations
  • 24 h-Index
1985 …2020

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2020

Performance of candidate urinary biomarkers for pancreatic cancer - Correlation with pancreatic cyst malignant progression?

Yip-Schneider, M. T., Soufi, M., Carr, R. A., Flick, K. F., Wu, H., Colgate, C. L. & Schmidt, C. M., Mar 2020, In : American Journal of Surgery. 219, 3, p. 492-495 4 p.

Research output: Contribution to journalArticle

2019

A multimodality test to guide the management of patients with a pancreatic cyst

Springer, S., Masica, D. L., Molin, M. D., Douville, C., Thoburn, C. J., Afsari, B., Li, L., Cohen, J. D., Thompson, E., Allen, P. J., Klimstra, D. S., Schattner, M. A., Max Schmidt, C., Yip-Schneider, M., Simpson, R. E., Castillo, C. F. D., Mino-Kenudson, M., Brugge, W., Brand, R. E., Singhi, A. D. & 40 others, Scarpa, A., Lawlor, R., Salvia, R., Zamboni, G., Hong, S. M., Hwang, D. W., Jang, J. Y., Kwon, W., Swan, N., Geoghegan, J., Falconi, M., Crippa, S., Doglioni, C., Paulino, J., Schulick, R. D., Edil, B. H., Park, W., Yachida, S., Hijioka, S., Van Hooft, J., He, J., Weiss, M. J., Burkhart, R., Makary, M., Canto, M. I., Goggins, M. G., Ptak, J., Dobbyn, L., Schaefer, J., Sillman, N., Popoli, M., Klein, A. P., Tomasetti, C., Karchin, R., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Wolfgang, C. L., Hruban, R. H. & Lennon, A. M., Jul 17 2019, In : Science translational medicine. 11, 501, eaav4772.

Research output: Contribution to journalArticle

8 Scopus citations

A plasma-derived protein-metabolite multiplexed panel for early-stage pancreatic cancer

Fahrmann, J. F., Bantis, L. E., Capello, M., Scelo, G., Dennison, J. B., Patel, N., Murage, E., Vykoukal, J., Kundnani, D. L., Foretova, L., Fabianova, E., Holcatova, I., Janout, V., Feng, Z., Yip-Schneider, M., Zhang, J., Brand, R., Taguchi, A., Maitra, A., Brennan, P. & 2 others, Max Schmidt, C. & Hanash, S., Jan 1 2019, In : Journal of the National Cancer Institute. 111, 4, djy126.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Circulating Leptin and Branched Chain Amino Acids—Correlation with Intraductal Papillary Mucinous Neoplasm Dysplastic Grade

Yip-Schneider, M. T., Simpson, R., Carr, R. A., Wu, H., Fan, H., Liu, Z., Korc, M., Zhang, J. & Schmidt, C. M., May 15 2019, In : Journal of Gastrointestinal Surgery. 23, 5, p. 966-974 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Circulating Thrombospondin-2 enhances prediction of malignant intraductal papillary mucinous neoplasm

Simpson, R. E., Yip-Schneider, M. T., Wu, H., Fan, H., Liu, Z., Korc, M., Zhang, J. & Schmidt, C. M., Mar 2019, In : American Journal of Surgery. 217, 3, p. 425-428 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical criteria for integrated molecular pathology in intraductal papillary mucinous neoplasm: less is more

Simpson, R. E., Cockerill, N. J., Yip-Schneider, M. T., Ceppa, E. P., House, M. G., Zyromski, N. J., Nakeeb, A., Al-Haddad, M. A. & Schmidt, C. M., May 2019, In : HPB. 21, 5, p. 574-581 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pancreatic fluid interleukin-1β complements prostaglandin E2 and serum carbohydrate antigen 19-9 in prediction of intraductal papillary mucinous neoplasm dysplasia

Simpson, R. E., Yip-Schneider, M. T., Flick, K. F., Wu, H., Colgate, C. L. & Schmidt, C. M., Sep 1 2019, In : Pancreas. 48, 8, p. 1026-1031 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Proinsulin secretion is a persistent feature of type 1 diabetes

Sims, E. K., Bahnson, H. T., Nyalwidhe, J., Haataja, L., Davis, A. K., Speake, C., DiMeglio, L. A., Blum, J., Morris, M. A., Mirmira, R. G., Nadler, J., Mastracci, T. L., Marcovina, S., Qian, W. J., Yi, L., Swensen, A. C., Yip-Schneider, M., Schmidt, C. M., Considine, R. V., Arvan, P. & 2 others, Greenbaum, C. J. & Evans-Molina, C., Feb 1 2019, In : Diabetes care. 42, 2, p. 258-264 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2018

DNA profile components predict malignant outcomes in select cases of intraductal papillary mucinous neoplasm with negative cytology

Simpson, R. E., Cockerill, N. J., Yip-Schneider, M. T., Ceppa, E. P., House, M. G., Zyromski, N. J., Nakeeb, A., Al-Haddad, M. A. & Schmidt, C. M., Oct 2018, In : Surgery (United States). 164, 4, p. 712-718 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

Cohen, J. D., Javed, A. A., Thoburn, C., Wong, F., Tie, J., Gibbs, P., Schmidt, C. M., Yip-Schneider, M. T., Allen, P. J., Schattner, M., Brand, R. E., Singhi, A. D., Petersen, G. M., Hong, S. M., Kim, S. C., Falconi, M., Doglioni, C., Weiss, M. J., Ahuja, N., He, J. & 20 others, Makary, M. A., Maitra, A., Hanash, S. M., Dal Molin, M., Wang, Y., Li, L., Ptak, J., Dobbyn, L., Schaefer, J., Silliman, N., Popoli, M., Goggins, M. G., Hruban, R. H., Wolfgang, C. L., Klein, A. P., Tomasetti, C., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Lennon, A. M., Sep 19 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 38, p. 10202-10207 6 p.

Research output: Contribution to journalArticle

135 Scopus citations

Global protease activity profiling provides differential diagnosis of pancreatic cysts

Ivry, S. L., Sharib, J. M., Dominguez, D. A., Roy, N., Hatcher, S. E., Yip-Schneider, M. T., Schmidt, C. M., Brand, R. E., Park, W. G., Hebrok, M., Kim, G. E., O'Donoghue, A. J., Kirkwood, K. S. & Craik, C. S., Aug 15 2017, In : Clinical Cancer Research. 23, 16, p. 4865-4874 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pancreatic cyst fluid glucose: Rapid, inexpensive, and accurate diagnosis of mucinous pancreatic cysts

Carr, R. A., Yip-Schneider, M., Simpson, R. E., Dolejs, S., Schneider, J. G., Wu, H., Ceppa, E. P., Park, W. & Schmidt, C., Jan 1 2017, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

7 Scopus citations
9 Scopus citations
11 Scopus citations
2015

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Springer, S., Wang, Y., Dal Molin, M., Masica, D. L., Jiao, Y., Kinde, I., Blackford, A., Raman, S. P., Wolfgang, C. L., Tomita, T., Niknafs, N., Douville, C., Ptak, J., Dobbyn, L., Allen, P. J., Klimstra, D. S., Schattner, M. A., Schmidt, C. M., Yip-Schneider, M., Cummings, O. W. & 47 others, Brand, R. E., Zeh, H. J., Singhi, A. D., Scarpa, A., Salvia, R., Malleo, G., Zamboni, G., Falconi, M., Jang, J. Y., Kim, S. W., Kwon, W., Hong, S. M., Song, K. B., Kim, S. C., Swan, N., Murphy, J., Geoghegan, J., Brugge, W., Fernandez-Del Castillo, C., Mino-Kenudson, M., Schulick, R., Edil, B. H., Adsay, V., Paulino, J., Van Hooft, J., Yachida, S., Nara, S., Hiraoka, N., Yamao, K., Hijioka, S., Van Der Merwe, S., Goggins, M., Canto, M. I., Ahuja, N., Hirose, K., Makary, M., Weiss, M. J., Cameron, J., Pittman, M., Eshleman, J. R., Diaz, L. A., Papadopoulos, N., Kinzler, K. W., Karchin, R., Hruban, R. H., Vogelstein, B. & Lennon, A. M., Nov 2015, In : Gastroenterology. 149, 6, p. 1501-1510 10 p.

Research output: Contribution to journalArticle

175 Scopus citations

Factors influencing the cytotoxicity of α-methylene-γ-hydroxy esters against pancreatic cancer

Ramachandran, P. V., Helppi, M. A., Lehmkuhler, A. L., Marchi, J. M., Schmidt, C. M. & Yip-Schneider, M. T., Oct 1 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 19, p. 4270-4273 4 p.

Research output: Contribution to journalArticle

Targeted nuclear factor-kappaB suppression enhances gemcitabine response in human pancreatic tumor cell line murine xenografts

Waters, J. A., Matos, J., Yip-Schneider, M., Aguilar-Saavedra, J. R., Crean, C. D., Beane, J. D., Dumas, R. P., Suvannasankha, A. & Schmidt, C. M., Oct 1 2015, In : Surgery (United States). 158, 4, p. 881-889 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis

Chan, I. S., Guy, C. D., Machado, M. V., Wank, A., Kadiyala, V., Michelotti, G., Choi, S., Swiderska-Syn, M., Karaca, G., Pereira, T. A., Yip-Schneider, M. T., Max Schmidt, C. & Diehl, A. M., Mar 2014, In : Alcoholism: Clinical and Experimental Research. 38, 3, p. 787-800 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Vascular endothelial growth factor, a novel and highly accurate pancreatic fluid biomarker for serous pancreatic cysts

Yip-Schneider, M. T., Wu, H., Dumas, R. P., Hancock, B. A., Agaram, N., Radovich, M. & Schmidt, C. M., Apr 2014, In : Journal of the American College of Surgeons. 218, 4, p. 608-617 10 p.

Research output: Contribution to journalArticle

42 Scopus citations
2013

Dimethylaminoparthenolide and gemcitabine: A survival study using a genetically engineered mouse model of pancreatic cancer

Yip-Schneider, M. T., Wu, H., Stantz, K., Agaram, N., Crooks, P. A. & Schmidt, C. M., Apr 17 2013, In : BMC Cancer. 13, 194.

Research output: Contribution to journalArticle

20 Scopus citations

Efficacy of dimethylaminoparthenolide and sulindac in combination with gemcitabine in a genetically engineered mouse model of pancreatic cancer

Yip-Schneider, M. T., Wu, H., Hruban, R. H., Lowy, A. M., Crooks, P. A. & Schmidt, C. M., Jan 1 2013, In : Pancreas. 42, 1, p. 160-167 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activities

Ramachandran, P. V., Nicponski, D. R., Nair, H. N. G., Helppi, M. A., Gagare, P. D., Schmidt, C. M. & Yip-Schneider, M. T., Dec 15 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 24, p. 6911-6914 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

The first synthesis of a borylated α-methylene-γ-butyrolactone

Ramachandran, P. V., Nicponski, D. R., Drolet, M. P., Schmidt, C. M. & Yip-Schneider, M. T., Apr 1 2013, In : Future Medicinal Chemistry. 5, 6, p. 633-639 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

Dimethylamino Parthenolide Enhances the Inhibitory Effects of Gemcitabine in Human Pancreatic Cancer Cells

Holcomb, B. K., Yip-Schneider, M. T., Waters, J. A., Beane, J. D., Crooks, P. A. & Schmidt, C. M., Jul 1 2012, In : Journal of Gastrointestinal Surgery. 16, 7, p. 1333-1340 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

The proteome of normal pancreatic juice

Doyle, C. J., Yancey, K., Pitt, H. A., Wang, M., Bemis, K., Yip-Schneider, M. T., Sherman, S. T., Lillemoe, K. D., Goggins, M. D. & Schmidt, C. M., Mar 1 2012, In : Pancreas. 41, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2011

Alcohol Induces Liver Neoplasia in a Novel Alcohol-Preferring Rat Model

Yip-Schneider, M. T., Doyle, C. J., Mckillop, I. H., Wentz, S. C., Brandon-Warner, E., Matos, J. M., Sandrasegaran, K., Saxena, R., Hennig, M. E., Wu, H., Waters, J. A., Klein, P. J., Froehlich, J. C. & Max Schmidt, C., Dec 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 12, p. 2216-2225 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Role of fatty acid synthase in gemcitabine and radiation resistance of pancreatic cancers

Yang, Y., Liu, H., Li, Z., Zhao, Z., Yip-Schneider, M., Fan, Q., Max Schmidt, C., Gabriela Chiorean, E., Xie, J., Cheng, L., Chen, J. H. & Zhang, J. T., Mar 7 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Transforming growth factor α levels in pancreatic fluid

Doyle, C. J., Agaram, N. P., Yip-Schneider, M. T. & Schmidt, C. M., Mar 1 2011, In : Pancreas. 40, 2, p. 260-264 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
2010

Role of 14-3-3σ in poor prognosis and in radiation and drug resistance of human pancreatic cancers

Li, Z., Dong, Z., Myer, D., Yip-Schneider, M., Liu, J., Cui, P., Schmidt, C. M. & Zhang, J. T., Nov 1 2010, In : BMC Cancer. 10, 598.

Research output: Contribution to journalArticle

28 Scopus citations

Tailored α-methylene-γ-butyrolactones and their effects on growth suppression in pancreatic carcinoma cells

Ramachandran, P. V., Pratihar, D., Nair, H. N. G., Walters, M., Smith, S., Yip-Schneider, M. T., Wu, H. & Schmidt, C. M., Nov 15 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6620-6623 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

Targeting mitogen-activated protein Kinase Kinase with the inhibitor pd0325901 decreases hepatocellular carcinoma growth in vitro and in mouse model systems

Hennig, M., Yip-Schneider, M. T., Wentz, S., Wu, H., Hekmatyar, S. K., Klein, P., Bansal, N. & Max Schmidt, C., Apr 1 2010, In : Hepatology. 51, 4, p. 1218-1225 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2009

Ethanol-TGFα-MEK Signaling Promotes Growth of Human Hepatocellular Carcinoma

Hennig, M., Yip-Schneider, M. T., Klein, P., Wentz, S., Matos, J. M., Doyle, C., Choi, J., Wu, H., O'Mara, A., Menze, A., Noble, S., McKillop, I. H. & Schmidt, C. M., Jun 15 2009, In : Journal of Surgical Research. 154, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
27 Scopus citations

Sulindac Prevents Carcinogen-Induced Intrahepatic Cholangiocarcinoma Formation In Vivo

Wentz, S. C., Yip-Schneider, M. T., Gage, E. A., Saxena, R., Badve, S. & Schmidt, C. M., Nov 1 2009, In : Journal of Surgical Research. 157, 1, p. e87-e95

Research output: Contribution to journalArticle

5 Scopus citations
2008

Effect of celecoxib and the novel anti-cancer agent, dimethylamino- parthenolide, in a developmental model of pancreatic cancer

Yip-Schneider, M. T., Wu, H., Njoku, V., Ralstin, M., Holcomb, B., Crooks, P. A., Neelakantan, S., Sweeney, C. J. & Schmidt, C. M., Oct 1 2008, In : Pancreas. 37, 3, p. e45-e53

Research output: Contribution to journalArticle

23 Scopus citations

Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies

Holcomb, B., Yip-Schneider, M. T., Matos, J. M., Dixon, J., Kennard, J., Mahomed, J., Shanmugam, R., Sebolt-Leopold, J. & Schmidt, C. M., Jan 1 2008, In : Journal of Gastrointestinal Surgery. 12, 2, p. 288-296 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

PGE 2 in pancreatic cyst fluid helps differentiate IPMN from MCN and predict IPMN Dysplasia

Schmidt, C. M., Yip-Schneider, M. T., Ralstin, M. C., Wentz, S., DeWitt, J., Sherman, S., Howard, T. J., McHenry, L., Dutkevitch, S., Goggins, M., Nakeeb, A. & Lillemoe, K. D., Jan 1 2008, In : Journal of Gastrointestinal Surgery. 12, 2, p. 243-249 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Targeting MEK is effective chemoprevention of hepatocellular carcinoma in TGF-α-transgenic mice

Wentz, S. C., Wu, H., Yip-Schneider, M. T., Hennig, M., Klein, P. J., Sebolt-Leopold, J. & Schmidt, C. M., Jan 1 2008, In : Journal of Gastrointestinal Surgery. 12, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

The Effect of Doxorubicin on MEK-ERK Signaling Predicts Its Efficacy in HCC

Choi, J., Yip-Schneider, M., Albertin, F., Wiesenauer, C., Wang, Y. & Schmidt, C. M., Dec 1 2008, In : Journal of Surgical Research. 150, 2, p. 219-226 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
2007

Effect of Celecoxib and Novel Agent LC-1 in a Hamster Model of Lung Cancer

Vegeler, R. C., Yip-Schneider, M. T., Ralstin, M., Wu, H., Crooks, P. A., Neelakantan, S., Nakshatri, H., Sweeney, C. J. & Schmidt, C. M., Nov 1 2007, In : Journal of Surgical Research. 143, 1, p. 169-176 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo

Yip-Schneider, M. T., Wu, H., Ralstin, M., Yiannoutsos, C., Crooks, P. A., Neelakantan, S., Noble, S., Nakshatri, H., Sweeney, C. J. & Schmidt, C. M., Jun 1 2007, In : Molecular cancer therapeutics. 6, 6, p. 1736-1744 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
2006

Cyclooxygenase-2 expression in hamster and human pancreatic neoplasia

Crowell, P. L., Schmidt, C. M., Yip-Schneider, M. T., Savage, J. J., Hertzler, D. A. & Cummings, W. O., Jan 1 2006, In : Neoplasia. 8, 6, p. 437-445 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G 0-G1 cell cycle arrest

Ralstin, M. C., Gage, E. A., Yip-Schneider, M. T., Klein, P. J., Wiebke, E. A. & Schmidt, C. M., Jun 1 2006, In : Molecular Cancer Research. 4, 6, p. 387-399 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Restoring chemotherapy and hormonetherapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model

Shanmugam, R., Jayaprakasan, V., Gokmen-Polar, Y., Kelich, S., Miller, K. D., Yip-Schneider, M., Cheng, L., Bhat-Nakshatri, P., Sledge, G. W., Nakshatri, H., Zheng, Q. H., Miller, M. A., DeGrado, T., Hutchins, G. D. & Sweeney, C. J., Oct 1 2006, In : Prostate. 66, 14, p. 1498-1511 14 p.

Research output: Contribution to journalArticle

44 Scopus citations

The effects of a novel MEK inhibitor PD184161 on MEK-ERK signaling and growth in human liver cancer

Klein, P. J., Schmidt, C. M., Wiesenauer, C. A., Choi, J. N., Gage, E. A., Yip-Schneider, M. T., Wiebke, E. A., Wang, Y., Omer, C. & Sebolt-Leopold, J. S., Jan 2006, In : Neoplasia. 8, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

51 Scopus citations
2005

Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-κB pathway in pancreatic carcinoma cells

Yip-Schneider, M. T., Nakshatri, H., Sweeney, C. J., Marshall, M. S., Wiebke, E. A. & Schmidt, C. M., Apr 1 2005, In : Molecular cancer therapeutics. 4, 4, p. 587-594 8 p.

Research output: Contribution to journalArticle

102 Scopus citations
2004

Multiple anticancer effects of blocking MEK-ERK signaling in hepatocellular carcinoma

Wiesenauer, C. A., Yip-Schneider, M. T., Wang, Y. & Schmidt, C. M., Mar 1 2004, In : Journal of the American College of Surgeons. 198, 3, p. 410-421 12 p.

Research output: Contribution to journalArticle

81 Scopus citations
2003
25 Scopus citations

MEK Inhibition of Pancreatic Carcinoma Cells by U0126 and Its Effect in Combination with Sulindac

Yip-Schneider, M. T. & Schmidt, C. M., Nov 1 2003, In : Pancreas. 27, 4, p. 337-344 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
2002

Cyclo-oxygenase-2 expression in primary cancers of the lung and bladder compared to normal adjacent tissue

Sweeney, C. J., Marshall, M. S., Barnard, D. S., Heilman, D. K., Billings, S. D., Cheng, L., Marshall, S. J. & Yip-Schneider, M. T., Dec 1 2002, In : Cancer detection and prevention. 26, 3, p. 238-244 7 p.

Research output: Contribution to journalArticle

18 Scopus citations