Millie Georgiadis

  • 2342 Citations
  • 26 h-Index
1975 …2019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Millie Georgiadis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

DNA-(Apurinic or Apyrimidinic Site) Lyase Medicine & Life Sciences
Moloney murine leukemia virus Medicine & Life Sciences
DNA Medicine & Life Sciences
RNA-Directed DNA Polymerase Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Endonucleases Chemical Compounds
Oxidation-Reduction Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

NIH Grants 1975 2014

Oxidation-Reduction
Neoplasms
DNA-(Apurinic or Apyrimidinic Site) Lyase
Transcription Factors
Multifunctional Enzymes
RNA-Directed DNA Polymerase
Nucleic Acids
Cell Nucleus Active Transport
RNA
Enzymes

BIOMEDICAL MASS SPECTROMETRY

Georgiadis, M., Xu, Y., Garner, P., Holloszy, J., Tyler, A., Bray, G., Fomon, S., Walser, M., Sherman, W., Tylor, A., Baenziger, J., Kopple, J., Gemanas, J. P., Matthews, D., Kornfeld, S., Bier, D., Leventis, N., Gibson, H. W., Petrash, J. M., Zielinski, W., Aguilar-Salinas, C., Sih, C., Solomon, J., Mirkin, C., Germanas, J. P., Loeppky, R., Goldman, W., Lopate, G., Hofmann, S., Hopkins, T., Buynak, J., Domingues, M. R., Srivastava, N., Murray, R., Jacob, J., Hardy, L., Arnold, F., Parhofer, K., Semenkovich, C. F., Andrea Caumo, [. V., Majerus, P., Mantovani, A., Nichols, F., Hecht, M., Bonadonna, R., Ruoff, R., Leewenburgh, C., Davidson, B., Stumvoll, M., McKinney, M., Saccomani, M., Schroepfer, G., De Llado, T. F., Burrows, G., Cremer, S., Jones, S., Leeuwenburgh, C., Chang, Y., Arends, J. A. N., Wooley, K. L., Gaspar, P., Jaeger, D., Kini, A., Gates, K., Bhasin, S., Yi, C., Kohrt, W., Anderson, M., Latour, M., Rothman, N., Bier, D., Hasten, D., Paz-Sandoval, A., Patterson, B., Krut, L., Fung, L., Bosner, M., Interisano, S., Yarasheski, K., Sherry, A. D., Nyengaard, J., Heinecke, J., Wolf, M., Takakis, I., Roberts-Kirchhoff, E., Merabet, E., Barton, L., Aguilar-Salinas, C., Chen, D. A. N., Holman, R., Makara, G. M., Chiarelli, P., Heijligenbert, R., Vicini, P., Roberts, E. S., Rosales, M., Crowley, J., Caumo, A., Vincent, M., Lakschmi, V. M., Mohanakumar, T., Roy, B., Pulley, S., Zabrocki, J., Biolo, G., Nowatzke, W., Kisselev, B., Shibue, T., Roti Roti, J., Zeng, J., Judd, R., Davis, A., Kuntz, R., Demarini, D. M., Saunders, M., Barbara, W., Hoffman, R., Reepmeyer, [. V., Hale, C. C., Mohamed-Ali, V., Dugan, L., Guillame, D., Racette, S., Grayson, M., Krafft, G. A., Powell, T., Rice, C. M., Takakis, I., Leeuwenburgh, C., Roberts-Kirchhoff, E., Reepmeyer, J., Barton, L., Davis, A., Leach, G., Chen, D. A. N., Zachwieja, J. J., Holman, R., Chiarelli, P., Vicini, P., Volkert, W., Kwon, G., Roberts, E. S., Byun, J., Jaeger, D., Kini, A., Sampath, U., Caumo, A., Marshall, G. R., Lim, V., Gutsche, D., Setlow, P., Peng, Z., Bashkin, J. K., Hazen, S., Hasten, D. L., Loew, L., Zabrocki, J., Nowatzke, W., Kisselev, B., Shibue, T., Lerner, D., Judd, R., Johnson, R., Kuntz, R., Kirwan, J. P., Fung, L., Bosner, M., Pacifici, R., Burgers, P., Gokel, G., Davidson, B., Ido, Y., Interisano, S., Barbara, W., Hoffman, R., Strongin, R., Hale, C. C., Mohamed-Ali, V., Leventis, N., Williamson, J., Guillame, D., Krafft, G. A., Powell, T., Cremer, S., Knapp, S., Kuehne, M., Crowley, J., Gibson, H., Patterson, B., Xianlin, H., Zhongmin Alex, M., Zenser, T., Heinecke, J., Donaldson, W., Gilbertson, S., Wooley, K. L., Ramanadham, S., Cavalieri, E., Welch, M. J., Kenney, M., Manary, M., Yarasheski, K. E., Grayson, M., Rempel, D., Dugan, L., Gaspar, P., Mathai, G., Lavoie, E., Lakshmi, V., Ostlund, R. E., Vidavsky, I., Unanue, E., Moeller, K., Taylor, J. A., Hsu, F., Binnder, E., Vairamani, M., Starling, R., Harran, P. G., Jenkins, C., Listenberger, L., Zinna, E., Coppack, S., Loeppky, R., Chi, X., Powers, S., Gold, B., Narita, M., Cozzolino, M., Acharya, U., Tebas, P., Rathmacher, J., Lee, J., Zhimei, D., Schaffer, J., Mittendorfer, B., Pramanik, B., Zhu, M. E. I., Peng, Z., Creighton, D., Anderson, V., Du, J. O. Y., Cistola, D. P., Spilburg, C., Simpson, J., MacH, R., Holman, R., Montchamp, J., Gaut, J., Rhoades, E., Ying, L., Schonfeld, G., Fu, Y., Dieckgraefe, B. K., Thukkani, A., Frolov, A., Zozobrad, O., Ronenn, R., Polonsky, K., Albert, C., Cheng, H., Rosen, H., Yang, J., Spence, K., Breda, E., Bohlin, K., Pike, L., Zhang, W., Shea, M., Cassano, A., Manni, S., Mancuso, D. J., Merchak, A., Pettit, G., Sharma, V., Racette, S., Kim, J., Finck, B., Climent, L., Kohl, D., Villareal, D. T., Campbell, W., Hamvas, A., Carpentier, A., Kappock, J., Mondy, K. E., Madalengoitia, J., vandenborne, K., Sattler, F., De Brabander, J. K., Reeds, D., Zhang, K., Markaverich, B. M., Bao, S., Shoulars, K., Giblin, D., Wright, W. E., Doctorovich, F., Biehl, E., Gross, R., Desai, U. R., Paz-Sandoval, A., Bleeke, J., Semenkovich, C. F., Boyd, M., Abumrad, N. A., Laciny, E., Jenkins, C. M., Glass, T. E., Schaefer, J., Schroeder, E. T., Bhasin, S., Buynak, J., Fung, L. W., Binder, E., Cade, T., Birman, V., Cabrera, G., Brodsky, I., Groves, J. T., Yixin, S., Goldman, W., Gold, B., Yi, C., Walsmith, J., Nassir, F., Shanley, R. A., Michel, L. S., Tebas, P., Pranzatelli, M., Lee, J., Dore, T., Popham, D., Green, P., Walters, J., Ory, D., Gerber, M., Hyunwod, L., Reinecke, M., Xiong, S., Morse, G., Ng, M., Storer, T., Schmidt, R. E., Chaparro, J., Moran, J., Crimmins, D., Brown, J., Ippolito, J., Mani, S., Chakravarthy, M. V., Wang, Z., Dalla, C., Sharif, S., Wysocki, V., Wright, D., Yan, P., St. Geme, J., Harris, D., Pikaard, C. S., Hansen, T. H., Weber, J., Rohrs, H., Boyle, W., Evers, A. S., Song, H., Townsend, R. R., Allen, P. M., MacH, R., Chivers, P., Mahan, E., Ying, L., Klein, S., Weerasooriya, V., Gross, R., Marshall, G. R., Davis, F., Mentzelopoulos, V., Yang, J., Spence, K., Patterson, B., Lin, X. I., Magkos, F., Semenkovich, C. F., Westover, E., Gloer, J., Xianlin, H., Pericles, S., Wiemer, D., Jenkins, C. M., Laterza, O., Moon, S., Ladenson, R., Covey, D., Wildsmith, E., Nishino, K., Chen, C., Subramanian, S., Yin, K., Sourena, N., Messner, M., Owens, R. M., Jacobson, D., Akashi, S., Hughes, T., Kumar, R., Atwood, J., Wooley, K. L., Hultgren, S., Rosch, J., Farber, N., Rickert, P., Smith, C. J., Bleeke, J., Gordon, J. I., Holtzmann, D., Baranowska-Kortylewicz, J., Harbour, J., Crawford, P., Hanna, T., Crumrine, D., Beebe, D., Carlson, G., Petrash, J. M., van Gelder, R., Schroeder, E. T., Fitch, R., Goldman, W., Ross, F. P., Mutimura, E., Zheng, X., Sharp, J., Stahl, P., Ellis, M., Bessler, M., Hunstad, D. A., Yamada, K., Schaefer, J., Ming, Y., Achilefu, S., Bateman, R., Nerbonne, J. M., Ellenberger, T. E., Ley, T., Linehan, D., Okusanya, O., Xiang-Dong, L., Rosch, J. W., Vaid, J., Rice, J., Chen, H. A. O., Thalacker-Mercer, A. E., Nikolic, D., Biehl, E., Harbour, J. W., Dietzen, D., Brahmbhatt, V., Tebas, P., Rosenkranz, S. L., Sligar, S. G., Armbrecht, H. J., Malik, I., Son, D., Nodari, F., Dietrich, H., Baillargeon, J., Mondy, K. E., Pranzatelli, M., Grinspoon, S. K., Crimmins, D., Qing, M., Bashier, A., Moon, S. K., Samuel, B. S., Wilkinson, S. T., Carlier, P., Sutterwala, S., Prevelige, P. E., Schambelan, M., Lange, Y., Carper, M., Cheang, K., Wilson, B., Blankenship, R. E., Frieden, C., Holtzman, D., Stewart, S., Kappock, T. J., Franchi, E., Mauer, J., Shui, Y., Ramanadham, S., Henderson, J., Smith, V. G., Zhang, X., Chakravarthy, M. V., Sharma, V., Chang, L., Sattler, F., Li, H. U. I., Younan, X., Wooley, K. L., Loll, P., Di Cera, E., Bhasin, S., Flint, O., Lamerz, A., Sinko, P. J., Zhang, J., Thimgan, M., McLaughlin, L., O'Conner, R., Peterson, J., Soslau, G., Mirica, L., Zhang, O. U., Limbrick, D. D., Przybylski, M., Samant, S., Rhoades, E., Li, Y. U., Rader, J. S., Cheng, Q., Moley, K., Bose, R. O. N., Walter, M., Culican, S. M., Villeneuve, M., Zhang, S., Lin, X. I., Holy, T., Crawford, P., Minteer, S., Bangs, J. D., Grunfeld, C., Hultgren, S., Gross, R., Azen, S., Chen, F., Adair-Kirk, T., Haas, A., Kornbluth, J., McHowat, J., Turk, J., Zheng, N., Semenkovich, C. F., Routier, F., Michael, K., Yarasheski, K., Zhu, H. A. O., Reeds, D., Zhongmin Alex, M., vandenborne, K., Rapoport, S., Zhenheng, G., Angenent, L., Sibley, D. R., Bazan, G., Dallas, N., van Den Enden, M., Tipton, P., Wenhao, L., Tilton, R., Jones-Wilson, T. M., Clayton, T., Leboeuf, R., Shaish, A., Pendergrass, M., Thyssen, E., Downer, J. B., Babu, S., Rajyaguru, J., Anderson, C., Kwon, C., Evans, W., Haworth, D., Berberich, D., Rogers, B., Kilani, R., Jones-Wilson, T., Rutledge, L., Sherman, E., Nyengaard, [. V., Uhrich, K., Mishani, E., Schaal, B., Wolfson, M., Thalmann, I., Obrosova, [. V., Chang, K., Lanahan, M. V., Ziegenfuss, T. I. M., Steine, K., Wand, A., Whittlesey, B., Berliner, J., Hangauer, D., Triggle, D., Ford, D., Weiler, J., Mishani, E., Fobian, Y., Zhang, T., Kende, A., McGrath, J., Chen, X. I., Scarim, A., Gore, D., Townsend, C., Flanigan, M. J., Pakrasi, H., Gresham, A., Nagaraj, R., Hecht, S. M., Ornitz, D., Biehl, E. D., Ellen, L., Schoenwald, R., Protasiewicz, J., Schaefer, J., Klein, S., Corbett, J., Wright, G., States, D., Spiro, T., Hosmane, N., Gross, R., Grant, G., Carreira, E., Lakshmi, V., Schmitz, F., Gutsche, C. D., Bleeke, J., Cavalieri, E., Gordon, J., Allen, P., Sial, S., Oates, P. J., Wolf, C., Piwnica-Worms, D., van der Helm, D., Peterson, L., Sharp, P., Hupp, J., Birch, K., Frost, J., Kempe, K., Lavoie, E., Gilbertson, S., Lewis, W., Sidossis, L. S., Zachwieja, J., Volkert, W., Kwon, G., Rempel, D., Holtzer, A., Manary, M., Marshall, G., Lim, V., Welch, M. J., Bashkin, J. K., Hazen, S., Loew, L., Ramanadham, S., Kenney, M., Townsend, R., Ostlund, R., Vidavsky, I., Kirwan, J. P., Gokel, G., Yasuo, I., Xianlin, H., Unanue, E., Zhongmin Alex, M., Obrosova, I., Moeller, K., Teslenko, V. I. C., Stickle, D., Donaldson, W., Hickner, R., Taylor, J., Knapp, S., Williamson, J., Fong, H., Zhang, J., Turk, J., Goldberg, D., Piwnica-Worms, H., Buhro, W. & Gross, M.

National Institutes of Health

6/1/7512/31/14

Project: Research project

Cell Nucleus Active Transport
Isotopes
Oxidation-Reduction
Mass spectrometry
Organized Financing

Publications 1989 2019

  • 2342 Citations
  • 26 h-Index
  • 61 Article
  • 2 Chapter
  • 1 Conference contribution

Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1

Trilles, R., Beglov, D., Chen, Q., He, H., Wireman, R., Reed, A., Chennamadhavuni, S., Panek, J. S., Brown, L. E., Vajda, S., Porco, J. A., Kelley, M. & Georgiadis, M., Jan 1 2019, In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Endonucleases
Neoplasms
Oxidants
DNA Repair
21 Citations (Scopus)

Hachimoji DNA and RNA: A genetic system with eight building blocks

Hoshika, S., Leal, N. A., Kim, M. J., Kim, M. S., Karalkar, N. B., Kim, H. J., Bates, A. M., Watkins, N. E., SantaLucia, H. A., Meyer, A. J., DasGupta, S., Piccirilli, J. A., Ellington, A. D., SantaLucia, J., Georgiadis, M. & Benner, S. A., Jan 1 2019, In : Science. 363, 6429, p. 884-887 4 p.

Research output: Contribution to journalArticle

RNA
DNA
Thermodynamics
Molecular Structure
Names
3 Citations (Scopus)

"Skinny" and "fat" DNA: Two New Double Helices

Hoshika, S., Singh, I., Switzer, C., Molt, R. W., Leal, N. A., Kim, M. J., Kim, M. S., Kim, H. J., Georgiadis, M. & Benner, S. A., Sep 19 2018, In : Journal of the American Chemical Society. 140, 37, p. 11655-11660 6 p.

Research output: Contribution to journalArticle

Oils and fats
Hydrogen
Hydrogen bonds
DNA
Molecular recognition

Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide

Singh, I., Laos, R., Hoshika, S., Benner, S. A. & Georgiadis, M., Jan 1 2018, In : Nucleic Acids Research. 46, 15, p. 7977-7988 12 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Catalytic Domain
Nucleotides
Synthetic Biology
Thumb
5 Citations (Scopus)

Consecutive non-natural PZ nucleobase pairs in DNA impact helical structure as seen in 50 μs molecular dynamics simulations

Molt, R. W., Georgiadis, M. & Richards, N. G. J., Apr 20 2017, In : Nucleic Acids Research. 45, 7, p. 3643-3653 11 p.

Research output: Contribution to journalArticle

Molecular Dynamics Simulation
DNA
Oligonucleotides
Base Pairing
Hydrogen Bonding