Mircea Ivan

  • 9892 Citations
  • 33 h-Index
1993 …2019
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Publications 1993 2019

  • 9892 Citations
  • 33 h-Index
  • 68 Article
  • 2 Conference contribution
  • 2 Review article
  • 1 Letter
2019

Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover

Davis, H. M., Deosthale, P. J., Pacheco-Costa, R., Essex, A. L., Atkinson, E. G., Aref, M. W., Dilley, J. E., Bellido, T., Ivan, M., Allen, M. R. & Plotkin, L. I., Jan 1 2019, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Osteocytes
Bone Remodeling
Bone
Bone and Bones
Osteoclasts

Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers

Hancock, B. A., Chen, Y. H., Solzak, J. P., Ahmad, M. N., Wedge, D. C., Brinza, D., Scafe, C., Veitch, J., Gottimukkala, R., Short, W., Atale, R. V., Ivan, M., Badve, S. S., Schneider, B. P., Lu, X., Miller, K. D. & Radovich, M., Aug 5 2019, In : Breast Cancer Research. 21, 1, 87.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Recurrence
Drug Therapy
Residual Neoplasm
Mutation

The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress

Moreno Leon, L., Gautier, M., Allan, R., Ilié, M., Nottet, N., Pons, N., Paquet, A., Lebrigand, K., Truchi, M., Fassy, J., Magnone, V., Kinnebrew, G., Radovich, M., Cheok, M. H. C., Barbry, P., Vassaux, G., Marquette, C. H., Ponzio, G., Ivan, M., Pottier, N. & 3 others, Hofman, P., Mari, B. & Rezzonico, R., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Long Noncoding RNA
Oxidative Stress
Phenotype
Cisplatin
Clustered Regularly Interspaced Short Palindromic Repeats
2018

Enteral arg-gln dipeptide administration increases retinal docosahexaenoic acid and neuroprotectin D1 in a murine model of retinopathy of prematurity

Shaw, L. C., Calzi, S. L., Li, N., Moldovan, L., Sengupta-Caballero, N., Quigley, J. L., Ivan, M., Jun, B., Bazan, N. G., Boulton, M. E., Busik, J., Neu, J. & Grant, M. B., Feb 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 858-869 12 p.

Research output: Contribution to journalArticle

arginyl-glutamine
Retinopathy of Prematurity
Docosahexaenoic Acids
Dipeptides
Small Intestine
9 Citations (Scopus)

Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation

Sodi, V. L., Bacigalupa, Z. A., Ferrer, C. M., Lee, J. V., Gocal, W. A., Mukhopadhyay, D., Wellen, K. E., Ivan, M. & Reginato, M. J., Feb 15 2018, In : Oncogene. 37, 7, p. 924-934 11 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Lipid Metabolism
Food
Neoplasms
Lipids
4 Citations (Scopus)

P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim

Hu, P., Nebreda, A. R., Hanenberg, H., Kinnebrew, G. H., Ivan, M., Yoder, M., Filippi, M. D., Broxmeyer, H. & Kapur, R., Dec 1 2018, In : Nature Communications. 9, 1, 3518.

Research output: Contribution to journalArticle

anemias
Erythropoiesis
Erythropoietin
Epigenomics
Anemia
9 Citations (Scopus)

The Many Faces of Long Noncoding RNAs in Cancer

Wu, X., Tudoran, O. M., Calin, G. A. & Ivan, M., Sep 20 2018, In : Antioxidants and Redox Signaling. 29, 9, p. 922-935 14 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Tumors
Neoplasms
Neoplastic Processes
Human Genome
2017
29 Citations (Scopus)

Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging

Davis, H. M., Pacheco-Costa, R., Atkinson, E. G., Brun, L. R., Gortazar, A. R., Harris, J., Hiasa, M., Bolarinwa, S. A., Yoneda, T., Ivan, M., Bruzzaniti, A., Bellido, T. & Plotkin, L., 2017, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Osteocytes
Connexin 43
Osteogenesis
Apoptosis
Bone and Bones
26 Citations (Scopus)

Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow

Clinkenbeard, E. L., Hanudel, M. R., Stayrook, K. R., Appaiah, H. N., Farrow, E. G., Cass, T. A., Summers, L. J., Ip, C. S., Hum, J. M., Thomas, J. C., Ivan, M., Richine, B. M., Chan, R., Clemens, T. L., Schipani, E., Sabbagh, Y., Xu, L., Srour, E., Alvarez, M. B., Kacena, M. & 4 others, Salusky, I. B., Ganz, T., Nemeth, E. & White, K., Oct 27 2017, In : Haematologica. 102, 11, p. e427-e430

Research output: Contribution to journalLetter

Erythropoietin
Bone Marrow
Bone and Bones
fibroblast growth factor 23
39 Citations (Scopus)

The EGLN-HIF O2-Sensing System: Multiple Inputs and Feedbacks

Ivan, M. & Kaelin, W. G., Jun 15 2017, In : Molecular Cell. 66, 6, p. 772-779 8 p.

Research output: Contribution to journalReview article

Oxygen
Prolyl Hydroxylases
Untranslated RNA
Enzymes
Metabolic Networks and Pathways
9 Citations (Scopus)
MicroRNAs
Argonaute Proteins
Ovarian epithelial cancer
Gene Regulatory Networks
RNA
8 Citations (Scopus)

Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation

Brady, L. K., Wang, H., Radens, C. M., Bi, Y., Radovich, M., Maity, A., Ivan, C., Ivan, M., Barash, Y. & Koumenis, C., Oct 29 2017, In : PLoS Biology. 15, 10, e2002623.

Research output: Contribution to journalArticle

Gene Expression Profiling
transcriptomics
Introns
translation (genetics)
introns
2016
69 Citations (Scopus)

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

Redis, R. S., Vela, L. E., Lu, W., Ferreira de Oliveira, J., Ivan, C., Rodriguez-Aguayo, C., Adamoski, D., Pasculli, B., Taguchi, A., Chen, Y., Fernandez, A. F., Valledor, L., Van Roosbroeck, K., Chang, S., Shah, M., Kinnebrew, G., Han, L., Atlasi, Y., Cheung, L. H., Huang, G. Y. & 25 others, Monroig, P., Ramirez, M. S., Catela Ivkovic, T., Van, L., Ling, H., Gafà, R., Kapitanovic, S., Lanza, G., Bankson, J. A., Huang, P., Lai, S. Y., Bast, R. C., Rosenblum, M. G., Radovich, M., Ivan, M., Bartholomeusz, G., Liang, H., Fraga, M. F., Widger, W. R., Hanash, S., Berindan-Neagoe, I., Lopez-Berestein, G., Ambrosio, A. L. B., Gomes Dias, S. M. & Calin, G. A., Feb 18 2016, In : Molecular Cell. 61, 4, p. 520-534 15 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Alleles
Glutaminase
Alternative Splicing
Neoplasms
7 Citations (Scopus)

Correction to Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 [Molecular Cell 61, 520-534, (2016)]

Redis, R. S., Vela, L. E., Lu, W., Ferreira de Oliveira, J., Ivan, C., Rodriguez-Aguayo, C., Adamoski, D., Pasculli, B., Taguchi, A., Chen, Y., Fernandez, A. F., Valledor, L., Van Roosbroeck, K., Chang, S., Shah, M., Kinnebrew, G., Han, L., Atlasi, Y., Cheung, L. H., Huang, G. Y. & 25 others, Monroig, P., Ramirez, M. S., Catela Ivkovic, T., Van, L., Ling, H., Gafà, R., Kapitanovic, S., Lanza, G., Bankson, J. A., Huang, P., Lai, S. Y., Bast, R. C., Rosenblum, M. G., Radovich, M., Ivan, M., Bartholomeusz, G., Liang, H., Fraga, M. F., Widger, W. R., Hanash, S., Berindan-Neagoe, I., Lopez-Berestein, G., Ambrosio, A. L. B., Gomes Dias, S. M. & Calin, G. A., Feb 18 2016, In : Molecular Cell. 61, 4, p. 640 1 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Regulation of HIF1a under hypoxia by APE1/Ref-1 impacts CA9 expression: Dual targeting in patient-derived 3D pancreatic cancer models

Logsdon, D. P., Grimard, M., Luo, M., Shahda, S., Jiang, Y., Tong, Y., Yu, Z., Zyromski, N., Schipani, E., Carta, F., Supuran, C. T., Korc, M., Ivan, M., Kelley, M. & Fishel, M., Nov 1 2016, In : Molecular Cancer Therapeutics. 15, 11, p. 2722-2732 11 p.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Hypoxia-Inducible Factor 1
Transcription Factor AP-1
Pancreatic Neoplasms
Oxidation-Reduction
2015
25 Citations (Scopus)

Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2

Fishel, M., Wu, X., Devlin, C. M., Logsdon, D. P., Jiang, Y., Luo, M., He, Y., Yu, Z., Tong, Y., Lipking, K. P., Maitra, A., Rajeshkumar, N. V., Scandura, G., Kelley, M. & Ivan, M., Jan 30 2015, In : Journal of Biological Chemistry. 290, 5, p. 3057-3068 12 p.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Endonucleases
Oxidation-Reduction
Tumors
DNA Repair
110 Citations (Scopus)

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

Mantel, C. R., O'Leary, H. A., Chitteti, B. R., Huang, X., Cooper, S., Hangoc, G., Broustovetski, N., Srour, E., Lee, M. R., Messina-Graham, S., Haas, D., Falah, N., Kapur, R., Pelus, L., Bardeesy, N., Fitamant, J., Ivan, M., Kim, K. S. & Broxmeyer, H., Jun 18 2015, In : Cell. 161, 7, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Stem cells
Shock
Oxygen
81 Citations (Scopus)

Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression

Rupaimoole, R., Wu, S. Y., Pradeep, S., Ivan, C., Pecot, C. V., Gharpure, K. M., Nagaraja, A. S., Armaiz-Pena, G. N., McGuire, M., Zand, B., Dalton, H. J., Filant, J., Miller, J. B., Lu, C., Sadaoui, N. C., Mangala, L. S., Taylor, M., Van Den Beucken, T., Koch, E., Rodriguez-Aguayo, C. & 9 others, Huang, L., Bar-Eli, M., Wouters, B. G., Radovich, M., Ivan, M., Calin, G. A., Zhang, W., Lopez-Berestein, G. & Sood, A. K., 2015, In : Nature Communications. 5, 5202.

Research output: Contribution to journalArticle

biological evolution
hypoxia
MicroRNAs
progressions
Tumors
2014
17 Citations (Scopus)

Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing

Radovich, M., Clare, S. E., Atale, R., Pardo, I., Hancock, B. A., Solzak, J. P., Kassem, N., Mathieson, T., Storniolo, A. M., Rufenbarger, C., Lillemoe, H. A., Blosser, R. J., Choi, M. R., Sauder, C. A., Doxey, D., Henry, J. E., Hilligoss, E. E., Sakarya, O., Hyland, F. C., Hickenbotham, M. & 7 others, Zhu, J., Glasscock, J., Badve, S., Ivan, M., Liu, Y., Sledge, G. W. & Schneider, B., Jan 2014, In : Breast Cancer Research and Treatment. 143, 1, p. 57-68 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
RNA Sequence Analysis
Epithelium
Healthy Volunteers
Tissue Banks
8 Citations (Scopus)

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma

Lakhter, A. J., Hamilton, J., Dagher, P., Mukkamala, S., Hato, T., Dong, X., Mayo, L., Harris, R., Shekhar, A., Ivan, M., Broustovetski, N. & Naidu, S., 2014, In : Oncotarget. 5, 24, p. 12694-12703 10 p.

Research output: Contribution to journalArticle

Vitamin K 3
Oxidative Phosphorylation
Glycolysis
Melanoma
Cell Death
6 Citations (Scopus)

Gene expression analysis reveals distinct pathways of resistance to bevacizumab in xenograft models of human ER-positive breast cancer

Polar, Y., Goswami, C. P., Toroni, R. A., Sanders, K. L., Mehta, R., Sirimalle, U., Tanasa, B., Shen, C., Li, L., Ivan, M., Badve, S. & Sledge, G. W., 2014, In : Journal of Cancer. 5, 8, p. 633-645 13 p.

Research output: Contribution to journalArticle

Heterografts
Vascular Endothelial Growth Factor A
Breast Neoplasms
Gene Expression
Endothelial Growth Factors
45 Citations (Scopus)

HypoxamiRs and cancer: From biology to targeted therapy

Gee, H. E., Ivan, C., Calin, G. A. & Ivan, M., Sep 10 2014, In : Antioxidants and Redox Signaling. 21, 8, p. 1220-1238 19 p.

Research output: Contribution to journalArticle

Tumors
MicroRNAs
Neoplasms
sulofenur
Genes
104 Citations (Scopus)

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

Van Den Beucken, T., Koch, E., Chu, K., Rupaimoole, R., Prickaerts, P., Adriaens, M., Voncken, J. W., Harris, A. L., Buffa, F. M., Haider, S., Starmans, M. H. W., Yao, C. Q., Ivan, M., Ivan, C., Pecot, C. V., Boutros, P. C., Sood, A. K., Koritzinsky, M. & Wouters, B. G., 2014, In : Nature Communications. 5, 5203.

Research output: Contribution to journalArticle

phenotype
prognosis
stem cells
hypoxia
Stem cells

MiR-210: Fine-tuning the hypoxic response

Ivan, M. & Huang, X., 2014, Advances in Experimental Medicine and Biology. Vol. 772. p. 205-227 23 p. (Advances in Experimental Medicine and Biology; vol. 772).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tumors
Tuning
MicroRNAs
Cells
Tissue
50 Citations (Scopus)

MiR-210: Fine-tuning the hypoxic response

Ivan, M. & Huang, X., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 772. p. 205-227 23 p. (Advances in Experimental Medicine and Biology; vol. 772).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tumors
Tuning
MicroRNAs
Cells
Tissue
2013
44 Citations (Scopus)

Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts

Kumar, K., Wigfield, S., Gee, H. E., Devlin, C. M., Singleton, D., Li, J. L., Buffa, F., Huffman, M., Sinn, A. L., Silver, J., Turley, H., Leek, R., Harris, A. L. & Ivan, M., Jun 2013, In : Journal of Molecular Medicine. 91, 6, p. 749-758 10 p.

Research output: Contribution to journalArticle

Heterografts
Nude Mice
Neoplasms
Glioblastoma
Pharmaceutical Preparations
59 Citations (Scopus)

HINCUTs in cancer: Hypoxia-induced noncoding ultraconserved transcripts

Ferdin, J., Nishida, N., Wu, X., Nicoloso, M. S., Shah, M. Y., Devlin, C., Ling, H., Shimizu, M., Kumar, K., Cortez, M. A., Ferracin, M., Bi, Y., Yang, D., Czerniak, B., Zhang, W., Schmittgen, T. D., Voorhoeve, M. P., Reginato, M. J., Negrini, M., Davuluri, R. V. & 3 others, Kunej, T., Ivan, M. & Calin, G. A., Dec 2013, In : Cell Death and Differentiation. 20, 12, p. 1675-1687 13 p.

Research output: Contribution to journalArticle

Neoplasms
Inteins
Oxygen
Untranslated RNA
Proteins
55 Citations (Scopus)

MiR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress

Lezina, L., Purmessur, N., Antonov, A. V., Ivanova, T., Karpova, E., Krishan, K., Ivan, M., Aksenova, V., Tentler, D., Garabadgiu, A. V., Melino, G. & Barlev, N. A., Dec 2013, In : Cell Death and Disease. 4, 12, e953.

Research output: Contribution to journalArticle

DNA Damage
Cell Cycle Checkpoints
MicroRNAs
Apoptosis
Neoplasms
2012

Dihydroceramide-based response to hypoxia (Journal of Biological Chemistry (2011) 286, (38069-38078))

Devlin, C. M., Lahm, T., Hubbard, W. C., Van Demark, M., Wang, K. C., Wu, X., Bielawska, A., Obeid, L. M., Ivan, M. & Petrache, I., May 18 2012, In : Journal of Biological Chemistry. 287, 21, p. 17425 1 p.

Research output: Contribution to journalArticle

Hypoxia
dihydroceramide
24 Citations (Scopus)

Targeting the insulin growth factor and the vascular endothelial growth factor pathways in ovarian cancer

Shao, M., Hollar, S., Chambliss, D., Schmitt, J., Emerson, R., Chelladurai, B., Perkins, S., Ivan, M. & Matei, D., Jul 2012, In : Molecular Cancer Therapeutics. 11, 7, p. 1576-1586 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Vascular Endothelial Growth Factor A
Intercellular Signaling Peptides and Proteins
Insulin
Heterografts
2011
43 Citations (Scopus)

Dihydroceramide-based response to hypoxia

Devlin, C. M., Lahm, T., Hubbard, W. C., Van Demark, M., Wang, K. C., Wu, X., Bielawska, A., Obeid, L. M., Ivan, M. & Petrache, I., Nov 4 2011, In : Journal of Biological Chemistry. 286, 44, p. 38069-38078 10 p.

Research output: Contribution to journalArticle

Ceramides
Cell proliferation
Cell Proliferation
Oxygen
Oxygen sensors
50 Citations (Scopus)

Impact of APE1/ref-1 redox inhibition on pancreatic tumor growth

Fishel, M., Jiang, Y., Rajeshkumar, N. V., Scandura, G., Sinn, A. L., He, Y., Shen, C., Jones, D. R., Pollok, K., Ivan, M., Maitra, A. & Kelley, M., Sep 2011, In : Molecular Cancer Therapeutics. 10, 9, p. 1698-1708 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Oxidation-Reduction
Growth
Neoplasms
Transcription Factor AP-1
243 Citations (Scopus)

MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways

Rao, X., Di Leva, G., Li, M., Fang, F., Devlin, C., Hartman-Frey, C., Burow, M. E., Ivan, M., Croce, C. M. & Nephew, K., Mar 3 2011, In : Oncogene. 30, 9, p. 1082-1097 16 p.

Research output: Contribution to journalArticle

MicroRNAs
Breast Neoplasms
Estrogen Receptors
Growth
fulvestrant
171 Citations (Scopus)

MiR-210: More than a silent player in hypoxia

Devlin, C., Greco, S., Martelli, F. & Ivan, M., Feb 2011, In : IUBMB Life. 63, 2, p. 94-100 7 p.

Research output: Contribution to journalArticle

MicroRNAs
Tumors
Neoplasms
Metabolism
DNA Repair
29 Citations (Scopus)

PDGF induced microRNA alterations in cancer cells

Shao, M., Rossi, S., Chelladurai, B., Shimizu, M., Ntukogu, O., Ivan, M., Calin, G. A. & Matei, D., May 2011, In : Nucleic Acids Research. 39, 10, p. 4035-4047 13 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor
MicroRNAs
Neoplasms
Glioblastoma
Epidermal Growth Factor Receptor
2010
4 Citations (Scopus)

Blockade of FGF signaling: Therapeutic promise for ovarian cancer

Ivan, M. & Matei, D., Sep 1 2010, In : Cancer Biology and Therapy. 10, 5, p. 505-508 4 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Fibroblast Growth Factors
Alternative Splicing
Antineoplastic Agents
Ovarian Neoplasms
122 Citations (Scopus)

microRNA: Emerging therapeutic targets in acute ischemic diseases

Fasanaro, P., Greco, S., Ivan, M., Capogrossi, M. C. & Martelli, F., Jan 2010, In : Pharmacology and Therapeutics. 125, 1, p. 92-104 13 p.

Research output: Contribution to journalArticle

Acute Disease
MicroRNAs
Ischemia
Therapeutics
Untranslated RNA
219 Citations (Scopus)

MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU

Favaro, E., Ramachandran, A., McCormick, R., Gee, H., Blancher, C., Crosby, M., Devlin, C., Blick, C., Buffa, F., Li, J. L., Vojnovic, B., das Neves, R. P., Glazer, P., Iborra, F., Ivan, M., Ragoussis, J. & Harris, A. L., 2010, In : PLoS One. 5, 4, e10345.

Research output: Contribution to journalArticle

sulofenur
Iron-Sulfur Proteins
Citric Acid Cycle
tricarboxylic acid cycle
MicroRNAs
36 Citations (Scopus)

MicroRNAs in cancer. From bench to bedside

Angelica Cortez, M., Ivan, C., Zhou, P., Wu, X., Ivan, M. & Adrian Calin, G., 2010, In : Advances in Cancer Research. 108, C, p. 113-157 45 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Untranslated RNA
Regulator Genes
Genome
2009
188 Citations (Scopus)

An integrated approach for experimental target identification of hypoxia-induced miR-210

Fasanaro, P., Greco, S., Lorenzi, M., Pescatori, M., Brioschi, M., Kulshreshtha, R., Banfi, C., Stubbs, A., Calin, G. A., Ivan, M., Capogrossi, M. C. & Martelli, F., Dec 11 2009, In : Journal of Biological Chemistry. 284, 50, p. 35134-35143 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Endothelial cells
sulofenur
Endothelial Cells
RNA-Induced Silencing Complex
60 Citations (Scopus)

Emerging roles of microRNAs in the molecular responses to hypoxia

Crosby, M. E., Devlin, C. M., Glazer, P. M., Calin, G. A. & Ivan, M., Nov 2009, In : Current Pharmaceutical Design. 15, 33, p. 3861-3866 6 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Tumor Microenvironment
DNA Repair
DNA Damage

Erratum: Article on MicroRNAs and DNA repair (Cancer Res (2009) 69 (1221:1229))

Crosby, M. E., Kulshreshtha, R., Ivan, M. & Glazer, P. M., Apr 1 2009, In : Cancer Research. 69, 7, p. 3240 1 p.

Research output: Contribution to journalArticle

MicroRNAs
DNA Repair
Neoplasms
3 Citations (Scopus)

"Micro"-management of DNA repair genes by hypoxia

Crosby, M. E., Glazer, P. M. & Ivan, M., Dec 15 2009, In : Cell Cycle. 8, 24, p. 4009-4010 2 p.

Research output: Contribution to journalArticle

DNA Repair
Genes
Neoplasms
Hypoxia
315 Citations (Scopus)

MicroRNA regulation of DNA repair gene expression in hypoxic stress

Crosby, M. E., Kulshreshtha, R., Ivan, M. & Glazer, P. M., Feb 1 2009, In : Cancer Research. 69, 3, p. 1221-1229 9 p.

Research output: Contribution to journalArticle

MicroRNAs
DNA Repair
Gene Expression
3' Untranslated Regions
Hypoxia-Inducible Factor 1

Molecular responses to hypoxia: Ancient pathways, clinical promises

Kim, W. Y. & Ivan, M., Sep 2009, In : Journal of Cellular and Molecular Medicine. 13, 9 A, p. 2757-2758 2 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Cell Hypoxia
Critical Pathways
Signal Transduction
Medicine
2008
190 Citations (Scopus)

A microRNA component of the hypoxic response

Kulshreshtha, R., Davuluri, R. V., Calin, G. A. & Ivan, M., Apr 2008, In : Cell Death and Differentiation. 15, 4, p. 667-671 5 p.

Research output: Contribution to journalArticle

MicroRNAs
Pathologic Processes
Neoplasms
Carcinogenesis
Apoptosis
17 Citations (Scopus)

AMP-activated protein kinase is essential for survival in chronic hypoxia

Borger, D. R., Gavrilescu, L. C., Bucur, M. C., Ivan, M. & DeCaprio, J. A., May 30 2008, In : Biochemical and Biophysical Research Communications. 370, 2, p. 230-234 5 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Cells
Sirolimus
Renal Cell Carcinoma
Cell Survival
156 Citations (Scopus)

Hypoxia response and microRNAs: No longer two separate worlds

Ivan, M., Harris, A. L., Martelli, F. & Kulshreshtha, R., Sep 2008, In : Journal of Cellular and Molecular Medicine. 12, 5A, p. 1426-1431 6 p.

Research output: Contribution to journalArticle

MicroRNAs
Tumor Microenvironment
Lymphoma
Neoplasms
Breast Neoplasms
2 Citations (Scopus)
MicroRNAs
Medicine
2007
759 Citations (Scopus)

A microRNA signature of hypoxia

Kulshreshtha, R., Ferracin, M., Wojcik, S. E., Garzon, R., Alder, H., Agosto-Perez, F. J., Davuluri, R., Liu, C. G., Croce, C. M., Negrini, M., Calin, G. A. & Ivan, M., Mar 2007, In : Molecular and Cellular Biology. 27, 5, p. 1859-1867 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplastic Cell Transformation
Tumor Microenvironment
Neoplasms
Hypoxia