Monte Willis

MD, PhD, MBA, Deputy Director, Indiana Center for Musculoskeletal Health, Vice-Chair of Research, Department of Pathology & Lab Medicine

  • 635 Barnhill Drive, MS 5067

    46202 Indianapolis

    United States

  • 6703 Citations
  • 44 h-Index
19982020

Research output per year

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Publications

Article

Mixed aphasia in an adult male with AIDS

Willis, M. S., Bell, M. L., Najera, R. Y. & Wians, F. H., Oct 1 2002, In : Laboratory Medicine. 33, 10, p. 769-772 4 p.

Research output: Contribution to journalArticle

MMI-0100 inhibits cardiac fibrosis in a mouse model overexpressing cardiac myosin binding protein C

Meng, Q., Bhandary, B., Osinska, H., James, J., Xu, N., Shay-Winkler, K., Gulick, J., Willis, M. S., Lander, C. & Robbins, J., Sep 1 2017, In : Journal of the American Heart Association. 6, 9, e006590.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition

Xu, L., Yates, C. C., Lockyer, P., Xie, L., Bevilacqua, A., He, J., Lander, C., Patterson, C. & Willis, M., Dec 1 2014, In : Journal of Molecular and Cellular Cardiology. 77, p. 86-101 16 p.

Research output: Contribution to journalArticle

24 Scopus citations

Modeling the transition from decompensated to pathological hypertrophy

Pascual, F., Schisler, J. C., Grevengoed, T. J., Willis, M. S. & Coleman, R. A., Apr 17 2018, In : Journal of the American Heart Association. 7, 8, e008293.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Mouse cardiac acyl coenzyme A synthetase 1 deficiency impairs fatty acid oxidation and induces cardiac hypertrophy

Ellis, J. M., Mentock, S. M., DePetrillo, M. A., Koves, T. R., Sen, S., Watkins, S. M., Muoio, D. M., Cline, G. W., Taegtmeyer, H., Shulman, G. I., Willis, M. S. & Coleman, R. A., Mar 2011, In : Molecular and cellular biology. 31, 6, p. 1252-1262 11 p.

Research output: Contribution to journalArticle

Open Access
111 Scopus citations

Multiple positive sweat chloride tests in an infant asymptomatic for cystic fibrosis

Cotten, S. W., Bender, L. M. & Willis, M. S., Feb 1 2012, In : Laboratory Medicine. 43, 2, p. 1-5 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo

Mattox, T. A., Young, M. E., Rubel, C. E., Spaniel, C., Rodríguez, J. E., Grevengoed, T. J., Gautel, M., Xu, Z., Anderson, E. J. & Willis, M. S., Jun 2014, In : Journal of Bioenergetics and Biomembranes. 46, 3, p. 173-187 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo

Wadosky, K. M., Berthiaume, J. M., Tang, W., Zungu, M., Portman, M. A., Gerdes, A. M. & Willis, M. S., Apr 2016, In : Journal of Molecular Endocrinology. 56, 3, p. 273-290 18 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

He, J., Quintana, M. T., Sullivan, J., Parry, T., Grevengoed, T., Schisler, J. C., Hill, J. A., Yates, C. C., Mapanga, R. F., Essop, M. F., Stansfield, W. E., Bain, J. R., Newgard, C. B., Muehlbauer, M. J., Han, Y., Clarke, B. A. & Willis, M. S., Aug 5 2015, In : Cardiovascular Diabetology. 14, 1, 97.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo

Willis, M. S., Ike, C., Li, L., Wang, D. Z., Glass, D. J. & Patterson, C., Mar 2007, In : Circulation research. 100, 4, p. 456-459 4 p.

Research output: Contribution to journalArticle

Open Access
140 Scopus citations

Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo

Willis, M. S., Wadosky, K. M., Rodríguez, J. E., Schisler, J. C., Lockyer, P., Hilliard, E. G., Glass, D. J. & Patterson, C., Jan 1 2014, In : Cell Biochemistry and Function. 32, 1, p. 39-50 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling

Wadosky, K. M., Rodríguez, J. E., Hite, R. L., Min, J. N., Walton, B. L. & Willis, M. S., Apr 1 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 7, p. E723-E739

Research output: Contribution to journalArticle

21 Scopus citations

Muscle ring finger 1 mediates cardiac atrophy in vivo

Willis, M. S., Rojas, M., Li, L., Selzman, C. H., Tang, R. H., Stansfield, W. E., Rodriguez, J. E., Glass, D. J. & Patterson, C., Apr 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 4, p. H997-H1006

Research output: Contribution to journalArticle

72 Scopus citations

Muscle RING finger-1 promotes a maladaptive phenotype in chronic hypoxia-induced right ventricular remodeling

Campen, M. J., Paffett, M. L., Colombo, E. S., Lucas, S. N., Anderson, T., Nysus, M., Norenberg, J. P., Gershman, B., Hesterman, J., Hoppin, J. & Willis, M., May 8 2014, In : PLoS ONE. 9, 5, e97084.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet

Quintana, M. T., He, J., Sullivan, J., Grevengoed, T., Schisler, J., Han, Y., Hill, J. A., Yates, C. C., Stansfield, W. E., Mapanga, R. F., Essop, M. F., Muehlbauer, M. J., Newgard, C. B., Bain, J. R. & Willis, M. S., Dec 12 2015, In : BMC Endocrine Disorders. 15, 1, 36.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice

Oakley, R. H., Campen, M. J., Paffett, M. L., Chen, X., Wang, Z., Parry, T. L., Hillhouse, C., Cidlowski, J. A. & Willis, M. S., Sep 21 2018, In : BMC Medical Genetics. 19, 1, 175.

Research output: Contribution to journalArticle

Open Access

Myosin light chain phosphorylation is critical for adaptation to cardiac stress

Warren, S. A., Briggs, L. E., Zeng, H., Chuang, J., Chang, E. I., Terada, R., Li, M., Swanson, M. S., Lecker, S. H., Willis, M. S., Spinale, F. G., Maupin-Furlowe, J., McMullen, J. R., Moss, R. L. & Kasahara, H., 2012, In : Circulation. 126, 22, p. 2575-2588 14 p.

Research output: Contribution to journalArticle

66 Scopus citations

Nasal Discharge in a 50-Year-Old Woman

Chamberlain, W., White, M. D., Wians, F. H. & Willis, M. S., May 1 2004, In : Laboratory Medicine. 35, 5, p. 279-283 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Nebulized Delivery of the MAPKAP Kinase 2 Peptide Inhibitor MMI-0100 Protects Against Ischemia-Induced Systolic Dysfunction

Brown, D. I., Cooley, B. C., Quintana, M. T., Lander, C. & Willis, M. S., Sep 1 2016, In : International Journal of Peptide Research and Therapeutics. 22, 3, p. 317-324 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neck pain and rash in an 18-year-old student

Willis, M., Roth, M. & Gilligan, P., Jul 2005, In : Laboratory Medicine. 36, 7, p. 419-423 5 p.

Research output: Contribution to journalArticle

Open Access

New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis

Tian, S., Nakamura, J., Hiller, S., Simington, S., Holley, D. W., Mota, R., Willis, M. S., Bultman, S. J., Luft, J. C., DeSimone, J. M., Jia, Z., Maeda, N. & Yi, X., Oct 1 2020, In : Vascular Pharmacology. 133-134, 106777.

Research output: Contribution to journalArticle

NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo

Wysong, A., Couch, M., Shadfar, S., Li, L., Rodriguez, J. E., Asher, S., Yin, X., Gore, M., Baldwin, A., Patterson, C. & Willis, M. S., Mar 2011, In : American Journal of Pathology. 178, 3, p. 1059-1068 10 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes

Banerjee, R., He, J., Spaniel, C., Quintana, M. T., Wang, Z., Bain, J. R., Newgard, C. B., Muehlbauer, M. J. & Willis, M. S., Apr 1 2015, In : Metabolomics. 11, 2, p. 312-322 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Non-targeted metabolomics analysis of Golden Retriever Muscular Dystrophy-affected muscles reveals alterations in arginine and proline metabolism, and elevations in glutamic and oleic acid in vivo

Abdullah, M., Kornegay, J. N., Honcoop, A., Parry, T. L., Balog-Alvarez, C. J., O’Neal, S. K., Bain, J. R., Muehlbauer, M. J., Newgard, C. B., Patterson, C. & Willis, M. S., Sep 2017, In : Metabolites. 7, 3, 38.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Non-targeted metabolomics analysis of the effects of tyrosine kinase inhibitors sunitinib and erlotinib on heart, muscle, liver and serum metabolism in vivo

Jensen, B. C., Parry, T. L., Huang, W., Ilaiwy, A., Bain, J. R., Muehlbauer, M. J., O’Neal, S. K., Patterson, C., Johnson, G. L. & Willis, M. S., Sep 1 2017, In : Metabolites. 7, 3, 31.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis

Banerjee, R., Bultman, S. J., Holley, D., Hillhouse, C., Bain, J. R., Newgard, C. B., Muehlbauer, M. J. & Willis, M. S., Oct 7 2015, In : Metabolomics. 11, 5, p. 1287-1301 15 p.

Research output: Contribution to journalArticle

23 Scopus citations

Obesity, macrophage migration inhibitory factor, and weight loss

Church, T. S., Willis, M. S., Priest, E. L., LaMonte, M. J., Earnest, C. P., Wilkinson, W. J., Wilson, D. A. & Giroir, B. P., Jun 1 2005, In : International Journal of Obesity. 29, 6, p. 675-681 7 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo

Shadfar, S., Couch, M. E., McKinney, K. A., Weinstein, L. J., Yin, X., Rodriguez, J. E., Guttridge, D. C. & Willis, M., Jul 2011, In : Nutrition and Cancer. 63, 5, p. 749-762 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

Performance comparison of capillary and agarose gel electrophoresis for the identification and characterization of monoclonal immunoglobulins

McCudden, C. R., Mathews, S. P., Hainsworth, S. A., Chapman, J. F., Hammett-Stabler, C. A., Willis, M. S. & Grenache, D. G., Mar 1 2008, In : American journal of clinical pathology. 129, 3, p. 451-458 8 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Periumbilical rash in an immunosuppressed patient

White, M. D., Willis, M. S., Fuda, F. S., Gander, R. M. & Southern, P. M., Jun 1 2004, In : Laboratory Medicine. 35, 6, p. 346-349 4 p.

Research output: Contribution to journalArticle

Open Access

Persistent low concentration of human chorionic gonadotropin in a nonpregnant woman

McCudden, C. R., Willis, M. S. & Grenache, D. G., Jan 1 2008, In : Clinical chemistry. 54, 1, p. 209-213 5 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function

McCormick, M. E., Collins, C., Makarewich, C. A., Chen, Z., Rojas, M., Willis, M. S., Houser, S. R. & Tzima, E., Jan 19 2015, In : Journal of the American Heart Association. 4, 1, p. e001210

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
3 Scopus citations

Post-translationally modified muscle-specific ubiquitin ligases as circulating biomarkers in experimental cancer cachexia

Mota, R., Rodríguez, J. E., Bonetto, A., O'Connell, T. M., Asher, S. A., Parry, T. L., Lockyer, P., McCudden, C. R., Couch, M. E. & Willis, M. S., Jan 1 2017, In : American Journal of Cancer Research. 7, 9, p. 1948-1958 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Precision-cut liver slices from diet-induced obese rats exposed to ethanol are susceptible to oxidative stress and increased fatty acid synthesis

Duryee, M. J., Willis, M. S., Schaffert, C. S., Reidelberger, R. D., Dusad, A., Anderson, D. R., Klassen, L. W. & Thiele, G. M., Feb 1 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 306, 3, p. G208-G217

Research output: Contribution to journalArticle

11 Scopus citations

Primary amoebic meningoencephalitis

Fuda, F. S., Sigauke, E., Cavuoti, D., Gander, R., Kroft, S. & Willis, M. S., Jan 1 2002, In : Laboratory Medicine. 33, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

Proteasome Inhibition Attenuates Infarct Size and Preserves Cardiac Function in a Murine Model of Myocardial Ischemia-Reperfusion Injury

Stansfield, W. E., Moss, N. C., Willis, M. S., Tang, R. & Selzman, C. H., Jul 1 2007, In : Annals of Thoracic Surgery. 84, 1, p. 120-125 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Proteasome inhibition promotes regression of left ventricular hypertrophy

Stansfield, W. E., Tang, R. H., Moss, N. C., Baldwin, A. S., Willis, M. S. & Selzman, C. H., Feb 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 2, p. H645-H650

Research output: Contribution to journalArticle

77 Scopus citations

Proximal Extremity Weakness and Altered Mental Status

Brouse, C. F. & Willis, M. S., Dec 1 2003, In : Laboratory Medicine. 34, 12, p. 836-841 6 p.

Research output: Contribution to journalArticle

Open Access

Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol

Thiele, G. M., Duryee, M. J., Freeman, T. L., Sorrell, M. F., Willis, M. S., Tuma, D. J. & Klassen, L. W., Nov 25 2005, In : Biochemical Pharmacology. 70, 11, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Recurrent nephrolithiasis in a 9-year-old child

Willis, M. S., Oct 2006, In : Laboratory Medicine. 37, 10, p. 613-616 4 p.

Research output: Contribution to journalArticle

Open Access

Reducing laboratory billing defects using six sigma principles

Levtzow, C. B. & Willis, M. S., Sep 1 2013, In : Laboratory Medicine. 44, 4, p. 358-371 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Refeeding syndrome in a severely malnourished child

Willis, T. S., Boswell, R. & Willis, M., Sep 2004, In : Laboratory Medicine. 35, 9, p. 548-552 5 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Regulation of large conductance Ca2+-activated K+ (BK) Channel β1 subunit expression by muscle RING finger protein 1 in diabetic vessels

Yi, F., Wang, H., Chai, Q., Wang, X., Shen, W. K., Willis, M. S., Lee, H. C. & Lu, T., Apr 11 2014, In : Journal of Biological Chemistry. 289, 15, p. 10853-10864 12 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Regulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy

Wadosky, K. M., Li, L., RodríGuez, J. E., Min, J. N., Bogan, D., Gonzalez, J., Patterson, C., Kornegay, J. N. & Willis, M., Oct 2011, In : Muscle and Nerve. 44, 4, p. 553-562 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Rib Fractures and Death from Deletion of Osteoblast βcatenin in Adult Mice Is Rescued by Corticosteroids

Duan, J. Z., Lee, Y., Jania, C., Gong, J., Rojas, M., Burk, L., Willis, M., Homeister, J., Tilley, S., Rubin, J. & Deb, A., Feb 5 2013, In : PloS one. 8, 2, e55757.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
4 Scopus citations

Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins

Duryee, M. J., Freeman, T. L., Willis, M. S., Hunter, C. D., Hamilton, B. C., Suzuki, H., Tuma, D. J., Klassen, L. W. & Thiele, G. M., Nov 2005, In : Molecular pharmacology. 68, 5, p. 1423-1430 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Selective inhibition of NF-kappa-B with NBD peptide reduces tumor- induced wasting in a murine model of cancer cachexia in vivo

Wysong, A., Asher, S. A., Yin, X., Gore, M. R., Weinstein, L., Guttridge, D. C., Baldwin, A. S., Couch, M. E. & Willis, M. S., Feb 11 2011, In : Journal of Cancer Science and Therapy. 3, 2, p. 22-29 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Self-discovered breast mass in a 38-year-old woman

Banet, N., Lininger, R. A., Willis, M. S. & McCudden, C. R., Feb 1 2011, In : Laboratory Medicine. 42, 2, p. 68-73 6 p.

Research output: Contribution to journalArticle

Open Access