Monte Willis

MD, PhD, MBA, Deputy Director, Indiana Center for Musculoskeletal Health, Vice-Chair of Research, Department of Pathology & Lab Medicine

  • 635 Barnhill Drive, MS 5067

    46202 Indianapolis

    United States

  • 6612 Citations
  • 44 h-Index
19982020

Research output per year

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Publications

2010

Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers

Jearawiriyapaisarn, N., Moulton, H. M., Sazani, P., Kole, R. & Willis, M. S., Feb 1 2010, In : Cardiovascular research. 85, 3, p. 444-453 10 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Minireview: Won't get fooled again: The nonmetabolic roles of peroxisome proliferator-activated receptors (PPARs) in the heart

Lockyer, P., Schisler, J. C., Patterson, C. & Willis, M. S., Jun 2010, In : Molecular Endocrinology. 24, 6, p. 1111-1119 9 p.

Research output: Contribution to journalShort survey

Open Access
19 Scopus citations

Sent to destroy: The ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease

Willis, M. S., Townley-Tilson, W. H. D., Kang, E. Y., Homeister, J. W. & Patterson, C., Feb 2010, In : Circulation research. 106, 3, p. 463-478 16 p.

Research output: Contribution to journalReview article

Open Access
133 Scopus citations

Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy

Adamo, C. M., Dai, D. F., Percival, J. M., Minami, E., Willis, M. S., Patrucco, E., Froehner, S. C. & Beavo, J. A., Nov 2 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 44, p. 19079-19083 5 p.

Research output: Contribution to journalArticle

120 Scopus citations

Sir Hans Adolf Krebs: Architect of metabolic cycles

Wilson, B. A., Schisler, J. C. & Willis, M. S., Jun 2010, In : Laboratory Medicine. 41, 6, p. 377-380 4 p.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

The challenges and complexities of thyroid hormone replacement

Kansagra, S. M., McCudden, C. R. & Willis, M. S., Jun 1 2010, In : Laboratory Medicine. 41, 6, p. 338-348 11 p.

Research output: Contribution to journalReview article

Open Access
9 Scopus citations

The therapeutic potential of heat shock proteins in cardiomyopathies due to mutations in cardiac structural proteins

Rodríguez, J. E. & Willis, M. S., Dec 1 2010, In : Journal of Molecular and Cellular Cardiology. 49, 6, p. 904-907 4 p.

Research output: Contribution to journalEditorial

The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy

Carrier, L., Schlossarek, S., Willis, M. S. & Eschenhagen, T., Jan 1 2010, In : Cardiovascular research. 85, 2, p. 330-338 9 p.

Research output: Contribution to journalReview article

Open Access
55 Scopus citations

Unexpected cause of anemia in a 45-year-old patient with acute lymphoblastic leukemia

Pendse, A., Fedoriw, Y. & Willis, M. S., Nov 1 2010, In : Laboratory Medicine. 41, 11, p. 645-648 4 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Urine crystals in a 1-year-old male

Fender, J., Willis, M. S. & Fedoriw, Y., Jul 1 2010, In : Laboratory Medicine. 41, 7, p. 388-392 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2009

A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling

Kelley, R., Ren, R., Pi, X., Wu, Y., Moreno, I., Willis, M., Moser, M., Ross, M., Podkowa, M., Attisano, L. & Patterson, C., Feb 23 2009, In : Journal of Cell Biology. 184, 4, p. 597-609 13 p.

Research output: Contribution to journalArticle

79 Scopus citations

Build it up-Tear it down: Protein quality control in the cardiac sarcomere

Willis, M. S., Schisler, J. C., Portbury, A. L. & Patterson, C., Feb 2009, In : Cardiovascular research. 81, 3, p. 439-448 10 p.

Research output: Contribution to journalReview article

Open Access
103 Scopus citations

Cardiac muscle ring finger-1 Increases susceptibility to heart failure in Vivo

Willis, M. S., Schisler, J. C., Li, L., Rodríguez, J. E., Hilliard, E. G., Charles, P. C. & Patterson, C., Jul 2 2009, In : Circulation research. 105, 1, p. 80-88 9 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Familial hypertrophic cardiomyopathy: Basic concepts and future molecular diagnostics

Rodríguez, J. E., McCudden, C. R. & Willis, M. S., Jun 1 2009, In : Clinical Biochemistry. 42, 9, p. 755-765 11 p.

Research output: Contribution to journalReview article

17 Scopus citations

MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice

Callis, T. E., Pandya, K., Hee, Y. S., Tang, R. H., Tatsuguchi, M., Huang, Z. P., Chen, J. F., Deng, Z., Gunn, B., Shumate, J., Willis, M. S., Selzman, C. H. & Wang, D. Z., Sep 1 2009, In : Journal of Clinical Investigation. 119, 9, p. 2772-2786 15 p.

Research output: Contribution to journalArticle

Open Access
584 Scopus citations

Muscle ring finger 1 mediates cardiac atrophy in vivo

Willis, M. S., Rojas, M., Li, L., Selzman, C. H., Tang, R. H., Stansfield, W. E., Rodriguez, J. E., Glass, D. J. & Patterson, C., Apr 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 4, p. H997-H1006

Research output: Contribution to journalArticle

72 Scopus citations

Recent advances in the detection of prostate cancer using epigenetic markers in commonly collected laboratory samples

Maxwell, A., McCudden, C. R., Wians, F. & Willis, M. S., Dec 1 2009, In : Laboratory Medicine. 40, 3, p. 171-178 8 p.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Seek and destroy: The ubiquitin-proteasome system in cardiac disease

Willis, M. S., Rodríoguez, J. E., Schisler, J. C. & Patterson, C., Dec 1 2009, In : Current Hypertension Reports. 11, 6, p. 396-405 10 p.

Research output: Contribution to journalReview article

15 Scopus citations
2008

Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease

Willis, M. S., Schisler, J. C. & Patterson, C., Jan 1 2008, In : Future Cardiology. 4, 1, p. 65-75 11 p.

Research output: Contribution to journalReview article

20 Scopus citations

Cystic fibrosis: newborn screening in America.

Kleven, D. T., McCudden, C. R. & Willis, M. S., Jul 1 2008, In : MLO: medical laboratory observer. 40, 7, p. 16-18, 22, 24-27

Research output: Contribution to journalReview article

13 Scopus citations

Hypercalcemia in a 56-year-old female

Pierce, K. A., Willis, M. S. & McCudden, C. R., Dec 1 2008, In : Laboratory Medicine. 39, 1, p. 23-28 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde

Duryee, M. J., Klassen, L. W., Jones, B. L., Willis, M. S., Tuma, D. J. & Thiele, G. M., Aug 1 2008, In : International Immunopharmacology. 8, 8, p. 1112-1118 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Inhibitory kappa B kinase-β is a target for specific nuclear factor kappa B-mediated delayed cardioprotection

Moss, N. C., Tang, R. H., Willis, M., Stansfield, W. E., Baldwin, A. S. & Selzman, C. H., Nov 1 2008, In : Journal of Thoracic and Cardiovascular Surgery. 136, 5, p. 1274-1279 6 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations

O'Connell, T. M., Ardeshirpour, F., Asher, S. A., Winnike, J. H., Yin, X., George, J., Guttridge, D. C., He, W., Wysong, A., Willis, M. S. & Couch, M. E., Jul 2 2008, In : Metabolomics. 4, 3, p. 216-225 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Performance comparison of capillary and agarose gel electrophoresis for the identification and characterization of monoclonal immunoglobulins

McCudden, C. R., Mathews, S. P., Hainsworth, S. A., Chapman, J. F., Hammett-Stabler, C. A., Willis, M. S. & Grenache, D. G., Mar 1 2008, In : American journal of clinical pathology. 129, 3, p. 451-458 8 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Persistent low concentration of human chorionic gonadotropin in a nonpregnant woman

McCudden, C. R., Willis, M. S. & Grenache, D. G., Jan 1 2008, In : Clinical chemistry. 54, 1, p. 209-213 5 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Proteasome inhibition promotes regression of left ventricular hypertrophy

Stansfield, W. E., Tang, R. H., Moss, N. C., Baldwin, A. S., Willis, M. S. & Selzman, C. H., Feb 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 2, p. H645-H650

Research output: Contribution to journalArticle

77 Scopus citations

The ubiquitin-proteasome system in cardiac dysfunction

Mearini, G., Schlossarek, S., Willis, M. S. & Carrier, L., Dec 1 2008, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1782, 12, p. 749-763 15 p.

Research output: Contribution to journalReview article

Open Access
105 Scopus citations

You spin me round: MAFbx/Atrogin-1 feeds forward on FOXO transcription factors (like a record)

Schisler, J. C., Willis, M. S. & Patterson, C., Feb 15 2008, In : Cell Cycle. 7, 4, p. 440-443 4 p.

Research output: Contribution to journalReview article

16 Scopus citations
2007

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

Li, H. H., Willis, M. S., Lockyer, P., Miller, N., McDonough, H., Glass, D. J. & Patterson, C., Nov 1 2007, In : Journal of Clinical Investigation. 117, 11, p. 3211-3223 13 p.

Research output: Contribution to journalArticle

Open Access
198 Scopus citations

Biclonal M-spike in a 7-year-old child

Fritchie, K. & Willis, M. S., Jun 1 2007, In : Laboratory Medicine. 38, 6, p. 347-351 5 p.

Research output: Contribution to journalArticle

Open Access

Blood bank management of sickle cell patients at comprehensive sickle cell centers

Afenyi-Annan, A., Willis, M. S., Konrad, T. R. & Lottenberg, R., Nov 1 2007, In : Transfusion. 47, 11, p. 2089-2097 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Bovine cardiac troponin T is not accurately quantified with a common human clinical immunoassay

Willis, M. S., Snyder, J. A., Poppenga, R. H. & Grenache, D. G., Jan 2007, In : Journal of Veterinary Diagnostic Investigation. 19, 1, p. 106-108 3 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Characterization of a Model to Independently Study Regression of Ventricular Hypertrophy

Stansfield, W. E., Rojas, M., Corn, D., Willis, M., Patterson, C., Smyth, S. S. & Selzman, C. H., Oct 1 2007, In : Journal of Surgical Research. 142, 2, p. 387-393 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Chest pain, dyspnea, and fatigue in a 57-year-old man

Roth, M., Aitsebaomo, J. & Willis, M. S., Sep 1 2007, In : Laboratory Medicine. 38, 9, p. 543-548 6 p.

Research output: Contribution to journalArticle

Open Access

IKKβ inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury

Moss, N. C., Stansfield, W. E., Willis, M. S., Tang, R. H. & Selzman, C. H., Oct 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 4, p. H2248-H2253

Research output: Contribution to journalArticle

81 Scopus citations

Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo

Willis, M. S., Ike, C., Li, L., Wang, D. Z., Glass, D. J. & Patterson, C., Mar 1 2007, In : Circulation research. 100, 4, p. 456-459 4 p.

Research output: Contribution to journalArticle

Open Access
138 Scopus citations

Proteasome Inhibition Attenuates Infarct Size and Preserves Cardiac Function in a Murine Model of Myocardial Ischemia-Reperfusion Injury

Stansfield, W. E., Moss, N. C., Willis, M. S., Tang, R. & Selzman, C. H., Jul 1 2007, In : Annals of Thoracic Surgery. 84, 1, p. 120-125 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

The bitter end: The ubiquitin-proteasome system and cardiac dysfunction

Patterson, C., Ike, C., Willis IV, P. W., Stouffer, G. A. & Willis, M. S., Mar 1 2007, In : Circulation. 115, 11, p. 1456-1463 8 p.

Research output: Contribution to journalReview article

Open Access
67 Scopus citations

The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle

Clarke, B. A., Drujan, D., Willis, M. S., Murphy, L. O., Corpina, R. A., Burova, E., Rakhilin, S. V., Stitt, T. N., Patterson, C., Latres, E. & Glass, D. J., Nov 7 2007, In : Cell Metabolism. 6, 5, p. 376-385 10 p.

Research output: Contribution to journalArticle

Open Access
403 Scopus citations
2006

DNA bar code: screening methods of colorectal cancer.

McCudden, C. & Willis, M. S., Nov 1 2006, In : MLO: medical laboratory observer. 38, 11, p. 10, 12, 14-15 passim; quiz 22-23

Research output: Contribution to journalArticle

Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition

Ramana, K. V., Willis, M. S., White, M. D., Horton, J. W., Dimaio, J. M., Srivastava, D., Bhatnagar, A. & Srivastava, S. K., Oct 1 2006, In : Circulation. 114, 17, p. 1838-1846 9 p.

Research output: Contribution to journalArticle

Open Access
75 Scopus citations

Hepatosplenomegaly in an 8-month-old child

Willis, M. S., Basinger, A. A., Fan, Z., Pendyal, S., Muenzer, J. & Hammett-Stabler, C., Nov 2006, In : Laboratory Medicine. 37, 11, p. 665-669+695

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Immunofixation reveals an apparent α heavy chain caused by precipitation of fibrinogen with IgA antiserum

Snyder, J. A., Willis, M. S. & Grenache, D. G., Jun 1 2006, In : Clinica Chimica Acta. 368, 1-2, p. 192-194 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Into the heart: The emerging role of the ubiquitin-proteasome system

Willis, M. S. & Patterson, C., Oct 1 2006, In : Journal of Molecular and Cellular Cardiology. 41, 4, p. 567-579 13 p.

Research output: Contribution to journalReview article

102 Scopus citations

Recurrent nephrolithiasis in a 9-year-old child

Willis, M. S., Oct 2006, In : Laboratory Medicine. 37, 10, p. 613-616 4 p.

Research output: Contribution to journalArticle

Open Access

Toxoplasma infection: Making the best use of laboratory tests

Southern, P. & Willis, M. S., Aug 1 2006, In : Infections in Medicine. 23, 8, p. 362-376 15 p.

Research output: Contribution to journalReview article

2005

Aortic valve insufficiency in a 45-year-old male

Willis, M., Roth, M. & Gilligan, P., Jun 2005, In : Laboratory Medicine. 36, 6, p. 345-349 5 p.

Research output: Contribution to journalArticle

Open Access

Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock

Binck, B. W., Tsen, M. F., Islas, M., White, D. J., Schultz, R. A., Willis, M. S., Garcia, J. V., Horton, J. W. & Thomas, J. A., Feb 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 288, 2 57-2, p. H577-H583

Research output: Contribution to journalArticle

29 Scopus citations

Effect of anemia on plasma concentrations of NT-proBNP

Willis, M. S., Lee, E. S. & Grenache, D. G., Aug 1 2005, In : Clinica Chimica Acta. 358, 1-2, p. 175-181 7 p.

Research output: Contribution to journalArticle

26 Scopus citations