Monte Willis

MD, PhD, MBA, Deputy Director, Indiana Center for Musculoskeletal Health, Vice-Chair of Research, Department of Pathology & Lab Medicine

  • 635 Barnhill Drive, MS 5067

    46202 Indianapolis

    United States

  • 6095 Citations
  • 44 h-Index
19982019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1998 2019

Filter
Article
2019
7 Citations (Scopus)

Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice

Oakley, R. H., Cruz-Topete, D., He, B., Foley, J. F., Myers, P. H., Xu, X., Gomez-Sanchez, C. E., Chambon, P., Willis, M. & Cidlowski, J. A., Apr 16 2019, In : Science Signaling. 12, 577, eaau9685.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Glucocorticoid Receptors
Cardiac Myocytes
Heart Diseases
Left Ventricular Dysfunction
5 Citations (Scopus)

Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle-Specific Ubiquitin Ligase MuRF1

Willis, M., Parry, T. L., Brown, D. I., Mota, R. I., Huang, W., Beak, J. Y., Sola, M., Zhou, C., Hicks, S. T., Caughey, M. C., D'agostino, R. B., Jordan, J., Hundley, W. G. & Jensen, B. C., Mar 1 2019, In : Circulation: Heart Failure. 12, 3, e005234.

Research output: Contribution to journalArticle

Striated Muscle
Anthracyclines
Ligases
Ubiquitin
Doxorubicin

F-box protein-32 down-regulates small-conductance calcium-activated potassium channel 2 in diabetic mouse atria

Ling, T. Y., Yi, F., Lu, T., Wang, X. L., Sun, X., Willis, M., Wu, L. Q., Shen, W. K., Adelman, J. P. & Lee, H. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 11, p. 4160-4168 9 p.

Research output: Contribution to journalArticle

Small-Conductance Calcium-Activated Potassium Channels
F-Box Proteins
Medical problems
Proteasome Endopeptidase Complex
Diabetes Mellitus

Identification of Metabolic Changes in Ileum, Jejunum, Skeletal Muscle, Liver, and Lung in a Continuous I.V. Pseudomonas aeruginosa Model of Sepsis Using Nontargeted Metabolomics Analysis

Ilaiwy, A., ten Have, G. A. M., Bain, J. R., Muehlbauer, M. J., O'Neal, S. K., Berthiaume, J. M., Parry, T. L., Deutz, N. E. & Willis, M., Sep 1 2019, In : American Journal of Pathology. 189, 9, p. 1797-1813 17 p.

Research output: Contribution to journalArticle

Metabolomics
Jejunum
Ileum
Pseudomonas aeruginosa
Sepsis

Image-Based Methods for Phase Estimation, Gating, and Temporal Superresolution of Cardiac Ultrasound

Chittajallu, D. R., McCormick, M., Gerber, S., Czernuszewicz, T. J., Gessner, R., Willis, M., Niethammer, M., Kwitt, R. & Aylward, S. R., Jan 1 2019, In : IEEE Transactions on Biomedical Engineering. 66, 1, p. 72-79 8 p., 8345790.

Research output: Contribution to journalArticle

Open Access
Electrocardiography
Ultrasonics
Hardware
Echocardiography
Time series
7 Citations (Scopus)

The sympathetic nervous system regulates skeletal muscle motor innervation and acetylcholine receptor stability

Rodrigues, A. C. Z., Messi, M. L., Wang, Z. M., Abba, M. C., Pereyra, A., Birbrair, A., Zhang, T., O’Meara, M., Kwan, P., Lopez, E. I. S., Willis, M., Mintz, A., Files, D. C., Furdui, C., Oppenheim, R. W. & Delbono, O., Mar 1 2019, In : Acta Physiologica. 225, 3, e13195.

Research output: Contribution to journalArticle

Sympathetic Nervous System
Cholinergic Receptors
Skeletal Muscle
Neuromuscular Junction
Myogenin
1 Citation (Scopus)

Walk the Line: The Role of Ubiquitin in Regulating Transcription in Myocytes

Suryadevara, V. & Willis, M., Sep 1 2019, In : Physiology (Bethesda, Md.). 34, 5, p. 327-340 14 p.

Research output: Contribution to journalArticle

Ubiquitin
Muscle Cells
Skeletal Muscle
Wasting Syndrome
Muscle Development
2018
1 Citation (Scopus)

Applicability of precision medicine approaches to managing hypertension in rural populations

Halladay, J. R., Lenhart, K. C., Robasky, K., Jones, W., Homan, W. F., Cummings, D. M., Cené, C. W., Hinderliter, A. L., Miller, C. L., Donahue, K. E., Garcia, B. A., Keyserling, T. C., Ammerman, A. S., Patterson, C., Dewalt, D. A., Johnston, L. F., Willis, M. & Schisler, J. C., Jun 1 2018, In : Journal of Personalized Medicine. 8, 2, 16.

Research output: Contribution to journalArticle

Open Access
Precision Medicine
Rural Population
Blood Pressure
Hypertension
Single Nucleotide Polymorphism
8 Citations (Scopus)

Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16

Shi, C. H., Rubel, C., Soss, S. E., Sanchez-Hodge, R., Zhang, S., Madrigal, S. C., Ravi, S., McDonough, H., Page, R. C., Chazin, W. J., Patterson, C., Mao, C. Y., Willis, M., Luo, H. Y., Li, Y. S., Stevens, D. A., Tang, M. B., Du, P., Wang, Y. H., Hu, Z. W. & 2 others, Xu, Y. M. & Schisler, J. C., Sep 1 2018, In : PLoS Genetics. 14, 9, e1007664.

Research output: Contribution to journalArticle

Open Access
cognition
Cognition
mutation
Ligases
ligases
2 Citations (Scopus)

Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study

Raffield, L. M., Ellis, J., Olson, N. C., Duan, Q., Li, J., Durda, P., Pankratz, N., Keating, B. J., Wassel, C. L., Cushman, M., Wilson, J. G., Gross, M. D., Tracy, R. P., Rich, S. S., Reiner, A. P., Li, Y., Willis, M., Lange, E. M. & Lange, L. A., Mar 1 2018, In : Journal of Human Genetics. 63, 3, p. 327-337 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Homocysteine
African Americans
Young Adult
Atherosclerosis
1 Citation (Scopus)

Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo

Mota, R., Parry, T. L., Yates, C. C., Qiang, Z., Eaton, S. C., Mwiza, J. M., Tulasi, D., Schisler, J. C., Patterson, C., Zaglia, T., Sandri, M. & Willis, M., Jul 1 2018, In : American Journal of Pathology. 188, 7, p. 1676-1692 17 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Fibrosis
Collagen
Matrix Metalloproteinase 8
Ligases
1 Citation (Scopus)

Modeling the transition from decompensated to pathological hypertrophy

Pascual, F., Schisler, J. C., Grevengoed, T. J., Willis, M. & Coleman, R. A., Apr 17 2018, In : Journal of the American Heart Association. 7, 8, e008293.

Research output: Contribution to journalArticle

Open Access
Hypertrophy
Metabolomics
Sirolimus
Gene Expression
Fibrosis

Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice

Oakley, R. H., Campen, M. J., Paffett, M. L., Chen, X., Wang, Z., Parry, T. L., Hillhouse, C., Cidlowski, J. A. & Willis, M., Sep 21 2018, In : BMC Medical Genetics. 19, 1, 175.

Research output: Contribution to journalArticle

Open Access
Ligases
Ubiquitin
Hypertrophy
Fingers
Muscles
2 Citations (Scopus)

Untargeted metabolomics analysis of ischemia–reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats

Parry, T. L., Starnes, J. W., O’Neal, S. K., Bain, J. R., Muehlbauer, M. J., Honcoop, A., Ilaiwy, A., Christopher, P., Patterson, C. & Willis, M., Jan 1 2018, In : Metabolomics. 14, 1, 8.

Research output: Contribution to journalArticle

Metabolomics
Heart Injuries
Rats
Pantothenic Acid
Biosynthesis
2017
3 Citations (Scopus)

A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity

Shimomoto, T., Collins, L. B., Yi, X., Holley, D. W., Zhang, Z., Tian, X., Uchida, K., Wang, C., Hörkkö, S., Willis, M., Gold, A., Bultman, S. J. & Nakamura, J., Feb 1 2017, In : PLoS ONE. 12, 2, e0172172.

Research output: Contribution to journalArticle

Open Access
atherosclerosis
Anti-Idiotypic Antibodies
Atherosclerosis
Enzyme-Linked Immunosorbent Assay
enzyme-linked immunosorbent assay
6 Citations (Scopus)

BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility

Willis, M., Holley, D. W., Wang, Z., Chen, X., Quintana, M., Jensen, B. C., Tannu, M., Parker, J., Jeyaraj, D., Jain, M. K., Wolfram, J. A., Lee, H. G. & Bultman, S. J., Apr 1 2017, In : Journal of Molecular and Cellular Cardiology. 105, p. 99-109 11 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Heart Failure
Genes
Cause of Death
Catalytic Domain
2 Citations (Scopus)

Clinical Evidence Supports a Protective Role for CXCL5 in Coronary Artery Disease

Ravi, S., Schuck, R. N., Hilliard, E., Lee, C. R., Dai, X., Lenhart, K., Willis, M., Jensen, B. C., Stouffer, G. A., Patterson, C. & Schisler, J. C., Dec 1 2017, In : American Journal of Pathology. 187, 12, p. 2895-2911 17 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Odds Ratio
Chemokines
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Quantitative Trait Loci
7 Citations (Scopus)

Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis

Jensen, B. C., Parry, T. L., Huang, W., Beak, J. Y., Ilaiwy, A., Bain, J. R., Newgard, C. B., Muehlbauer, M. J., Patterson, C., Johnson, G. L. & Willis, M., Dec 1 2017, In : British Journal of Pharmacology. 174, 24, p. 4797-4811 15 p.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Myocardium
Phosphotransferases
Liver
Taurine
5 Citations (Scopus)

Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes

Nakamura, J., Shimomoto, T., Collins, L. B., Holley, D. W., Zhang, Z., Barbee, J. M., Sharma, V., Tian, X., Kondo, T., Uchida, K., Yi, X., Perkins, DI. O., Willis, M., Gold, A. & Bultman, S. J., Dec 1 2017, In : Scientific Reports. 7, 1, 10787.

Research output: Contribution to journalArticle

Open Access
Formaldehyde
Epitopes
Lysine
Malondialdehyde
Atherosclerosis
8 Citations (Scopus)

Exercise-induced alterations in skeletal muscle, heart, liver, and serum metabolome identified by non-targeted metabolomics analysis

Starnes, J. W., Parry, T. L., O’Neal, S. K., Bain, J. R., Muehlbauer, M. J., Honcoop, A., Ilaiwy, A., Christopher, P. M., Patterson, C. & Willis, M., Jan 1 2017, In : Metabolites. 7, 3, 40.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Metabolome
Liver
alpha-Tocopherol
Muscle
5 Citations (Scopus)

Kinome and transcriptome profiling reveal broad and distinct activities of erlotinib, sunitinib, and sorafenib in the mouse heart and suggest cardiotoxicity from combined signal transducer and activator of transcription and epidermal growth factor receptor inhibition

Stuhlmiller, T. J., Zawistowski, J. S., Chen, X., Sciaky, N., Angus, S. P., Hicks, S. T., Parry, T. L., Huang, W., Beak, J. Y., Willis, M., Johnson, G. L. & Jensen, B. C., Oct 1 2017, In : Journal of the American Heart Association. 6, 10, e006635.

Research output: Contribution to journalArticle

Open Access
Gene Expression Profiling
Transducers
Epidermal Growth Factor Receptor
Phosphotransferases
Cardiac Myocytes
5 Citations (Scopus)

MMI-0100 inhibits cardiac fibrosis in a mouse model overexpressing cardiac myosin binding protein C

Meng, Q., Bhandary, B., Osinska, H., James, J., Xu, N., Shay-Winkler, K., Gulick, J., Willis, M., Lander, C. & Robbins, J., Sep 1 2017, In : Journal of the American Heart Association. 6, 9, e006590.

Research output: Contribution to journalArticle

Open Access
Cardiac Myosins
Fibrosis
Mitogen-Activated Protein Kinases
Protein Kinases
Peptide Fragments
6 Citations (Scopus)

Non-targeted metabolomics analysis of Golden Retriever Muscular Dystrophy-affected muscles reveals alterations in arginine and proline metabolism, and elevations in glutamic and oleic acid in vivo

Abdullah, M., Kornegay, J. N., Honcoop, A., Parry, T. L., Balog-Alvarez, C. J., O’Neal, S. K., Bain, J. R., Muehlbauer, M. J., Newgard, C. B., Patterson, C. & Willis, M., Sep 1 2017, In : Metabolites. 7, 3, 38.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Muscular Dystrophies
Oleic Acid
Proline
Metabolism
7 Citations (Scopus)

Non-targeted metabolomics analysis of the effects of tyrosine kinase inhibitors sunitinib and erlotinib on heart, muscle, liver and serum metabolism in vivo

Jensen, B. C., Parry, T. L., Huang, W., Ilaiwy, A., Bain, J. R., Muehlbauer, M. J., O’Neal, S. K., Patterson, C., Johnson, G. L. & Willis, M., Sep 1 2017, In : Metabolites. 7, 3, 31.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Metabolism
Liver
Protein-Tyrosine Kinases
Muscle
1 Citation (Scopus)

Post-translationally modified muscle-specific ubiquitin ligases as circulating biomarkers in experimental cancer cachexia

Mota, R., Rodríguez, J. E., Bonetto, A., O'Connell, T. M., Asher, S. A., Parry, T. L., Lockyer, P., McCudden, C. R., Couch, M. E. & Willis, M., Jan 1 2017, In : American Journal of Cancer Research. 7, 9, p. 1948-1958 11 p.

Research output: Contribution to journalArticle

Cachexia
Ligases
Ubiquitin
Biomarkers
Muscles
2 Citations (Scopus)

Ubiquitin ligases and posttranslational regulation of energy in the heart: The hand that feeds

Brown, D. I., Parry, T. L. & Willis, M., Jul 1 2017, In : Comprehensive Physiology. 7, 3, p. 841-862 22 p.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Hand
Proteasome Endopeptidase Complex
Heart Failure
4 Citations (Scopus)

Upregulation of autophagy genes and the unfolded protein response in human heart failure

Jensen, B. C., Bultman, S. J., Holley, D., Tang, W., de Ridder, G., Pizzo, S., Bowles, D. & Willis, M., Jan 30 2017, In : International Journal of Clinical and Experimental Medicine. 10, 1, p. 1051-1058 8 p., IJCEM0040108.

Research output: Contribution to journalArticle

Unfolded Protein Response
Autophagy
Up-Regulation
Heart Failure
Genes
2016
9 Citations (Scopus)

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo

Bultman, S. J., Holley, D. W., G De Ridder, G., Pizzo, S. V., Sidorova, T. N., Murray, K. T., Jensen, B. C., Wang, Z., Bevilacqua, A., Chen, X., Quintana, M. T., Tannu, M., Rosson, G. B., Pandya, K. & Willis, M., May 1 2016, In : Cardiovascular Pathology. 25, 3, p. 258-269 12 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Mitochondrial Dynamics
Cardiac Myocytes
Adenosine Triphosphatases
Homeostasis
7 Citations (Scopus)
Open Access
Autophagy
Ligases
Ubiquitin
Proteasome Endopeptidase Complex
Therapeutics
14 Citations (Scopus)

Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling

Quintana, M. T., Parry, T. L., He, J., Yates, C. C., Sidorova, T. N., Murray, K. T., Bain, J. R., Newgard, C. B., Muehlbauer, M. J., Eaton, S. C., Hishiya, A., Takayama, S. & Willis, M., Aug 1 2016, In : American Journal of Pathology. 186, 8, p. 1989-2007 19 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Cardiac Myocytes
Amyloid
Heart Failure
Mitochondrial Dynamics
2 Citations (Scopus)

Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis

Ilaiwy, A., Quintana, M. T., Bain, J. R., Muehlbauer, M. J., Brown, D. I., Stansfield, W. E. & Willis, M., Oct 1 2016, In : International Journal of Biochemistry and Cell Biology. 79, p. 80-92 13 p.

Research output: Contribution to journalArticle

Metabolomics
Muscular Atrophy
Metabolism
Muscle Cells
Proteolysis
17 Citations (Scopus)

Corticosteroids are essential for maintaining cardiovascular function in male mice

Cruz-Topete, D., Myers, P. H., Foley, J. F., Willis, M. & Cidlowski, J. A., Jul 1 2016, In : Endocrinology. 157, 7, p. 2759-2771 13 p.

Research output: Contribution to journalArticle

Open Access
Adrenalectomy
Adrenal Cortex Hormones
Left Ventricular Function
Mineralocorticoids
Electrocardiography
16 Citations (Scopus)

Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures

Kornegay, J. N., Bogan, D. J., Bogan, J. R., Dow, J. L., Wang, J., Fan, Z., Liu, N., Warsing, L. C., Grange, R. W., Ahn, M., Balog-Alvarez, C. J., Cotten, S. W., Willis, M., Brinkmeyer-Langford, C., Zhu, H., Palandra, J., Morris, C. A., Styner, M. A. & Wagner, K. R., Apr 4 2016, In : Skeletal Muscle. 6, 1, 14.

Research output: Contribution to journalArticle

Open Access
Myostatin
Dystrophin
Contracture
Joints
Dogs
6 Citations (Scopus)

Fenofibrate unexpectedly induces cardiac hypertrophy in mice lacking MuRF1

Parry, T. L., Desai, G., Schisler, J. C., Li, L., Quintana, M. T., Stanley, N., Lockyer, P., Patterson, C. & Willis, M., Mar 1 2016, In : Cardiovascular Pathology. 25, 2, p. 127-140 14 p.

Research output: Contribution to journalArticle

Fenofibrate
Cardiomegaly
PPAR alpha
Fingers
Muscles
7 Citations (Scopus)

Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo

Ilaiwy, A., Liu, M., Parry, T. L., Bain, J. R., Newgard, C. B., Schisler, J. C., Muehlbauer, M. J., Despa, F. & Willis, M., May 1 2016, In : Metabolomics. 12, 5, 95.

Research output: Contribution to journalArticle

Islet Amyloid Polypeptide
Cell signaling
Biosynthesis
Protein Biosynthesis
Liver
4 Citations (Scopus)

Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism

Files, D. C., Ilaiwy, A., Parry, T. L., Gibbs, K. W., Liu, C., Bain, J. R., Delbono, O., Muehlbauer, M. J. & Willis, M., Aug 1 2016, In : Metabolomics. 12, 8, 134.

Research output: Contribution to journalArticle

Lung Injury
Metabolism
Acute Lung Injury
Muscle
Skeletal Muscle
15 Citations (Scopus)

MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo

Wadosky, K. M., Berthiaume, J. M., Tang, W., Zungu, M., Portman, M. A., Gerdes, A. M. & Willis, M., Apr 1 2016, In : Journal of Molecular Endocrinology. 56, 3, p. 273-290 18 p.

Research output: Contribution to journalArticle

Open Access
Cardiomegaly
Fingers
Muscles
Ubiquitin
Proteasome Endopeptidase Complex
2 Citations (Scopus)

Nebulized Delivery of the MAPKAP Kinase 2 Peptide Inhibitor MMI-0100 Protects Against Ischemia-Induced Systolic Dysfunction

Brown, D. I., Cooley, B. C., Quintana, M. T., Lander, C. & Willis, M., Sep 1 2016, In : International Journal of Peptide Research and Therapeutics. 22, 3, p. 317-324 8 p.

Research output: Contribution to journalArticle

Cell death
Peptides
Ischemia
Echocardiography
Fibrosis
3 Citations (Scopus)

The alpha-1A adrenergic receptor agonist A61603 reduces cardiac polyunsaturated fatty acid and endocannabinoid metabolites associated with inflammation in vivo

Willis, M., Ilaiwy, A., Montgomery, M. D., Simpson, P. C. & Jensen, B. C., Oct 1 2016, In : Metabolomics. 12, 10, 155.

Research output: Contribution to journalArticle

A 61603
Adrenergic alpha-1 Receptors
Adrenergic alpha-Agonists
Endocannabinoids
Adrenergic Agonists
2015
16 Citations (Scopus)

Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin

Schisler, J. C., Grevengoed, T. J., Pascual, F., Cooper, D. E., Ellis, J. M., Paul, D. S., Willis, M., Patterson, C., Jia, W. & Coleman, R. A., Jan 1 2015, In : Journal of the American Heart Association. 4, 2, e001136.

Research output: Contribution to journalArticle

Open Access
Sirolimus
Glutathione
Glucose
Fatty Acids
Genes
4 Citations (Scopus)

Delayed contrast enhancement imaging of a murine model for ischemia reperfusion with carbon nanotube micro-CT

Burk, L. M., Wang, K. H., Wait, J. M., Kang, E., Willis, M., Lu, J., Zhou, O. & Lee, Y. Z., Jan 30 2015, In : PLoS ONE. 10, 1, e0115607.

Research output: Contribution to journalArticle

Open Access
carbon nanotubes
micro-computed tomography
Carbon Nanotubes
ischemia
myocardial infarction
19 Citations (Scopus)

Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis

Xie, L., Pi, X., Wang, Z., He, J., Willis, M. & Patterson, C., Mar 1 2015, In : Journal of Molecular and Cellular Cardiology. 80, p. 156-165 10 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Cardiac Myocytes
Apoptosis
Knockout Mice
Prolyl Hydroxylases
9 Citations (Scopus)

Endothelial inflammatory transcriptional responses to an altered plasma exposome following inhalation of diesel emissions

Schisler, J. C., Ronnebaum, S. M., Madden, M., Channell, M., Campen, M. & Willis, M., Apr 1 2015, In : Inhalation Toxicology. 27, 5, p. 272-280 9 p.

Research output: Contribution to journalArticle

Inhalation
Endothelial cells
Plasmas
Microarrays
Vehicle Emissions
14 Citations (Scopus)

Genetics and heart failure: A concise guide for the clinician

Skrzynia, C., Berg, J. S., Willis, M. & Jensen, B. C., Dec 1 2015, In : Current Cardiology Reviews. 11, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

Heart Failure
Dilated Cardiomyopathy
Mutation
Renin-Angiotensin System
Routine Diagnostic Tests
13 Citations (Scopus)

Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study

Li, J., Lange, L. A., Sabourin, J., Duan, Q., Valdar, W., Willis, M., Li, Y., Wilson, J. G. & Lange, E. M., Dec 1 2015, In : Journal of Human Genetics. 60, 12, p. 755-761 7 p.

Research output: Contribution to journalArticle

Exome
Lipoprotein(a)
Genome-Wide Association Study
Single Nucleotide Polymorphism
Serum
10 Citations (Scopus)

Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans

Li, J., Lange, L. A., Duan, Q., Lu, Y., Singleton, A. B., Zonderman, A. B., Evans, M. K., Li, Y., Taylor, H. A., Willis, M., Nalls, M., Wilson, J. G. & Lange, E. M., Jan 15 2015, In : Human Molecular Genetics. 24, 2, p. 572-581 10 p., ddu454.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Transferrin
Ferritins
African Americans
Iron
20 Citations (Scopus)

MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

He, J., Quintana, M. T., Sullivan, J., Parry, T., Grevengoed, T., Schisler, J. C., Hill, J. A., Yates, C. C., Mapanga, R. F., Essop, M. F., Stansfield, W. E., Bain, J. R., Newgard, C. B., Muehlbauer, M. J., Han, Y., Clarke, B. A. & Willis, M., Aug 5 2015, In : Cardiovascular Diabetology. 14, 1, 97.

Research output: Contribution to journalArticle

Open Access
Diabetic Cardiomyopathies
High Fat Diet
Fingers
Weight Gain
Peroxisome Proliferator-Activated Receptors
9 Citations (Scopus)

Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet

Quintana, M. T., He, J., Sullivan, J., Grevengoed, T., Schisler, J., Han, Y., Hill, J. A., Yates, C. C., Stansfield, W. E., Mapanga, R. F., Essop, M. F., Muehlbauer, M. J., Newgard, C. B., Bain, J. R. & Willis, M., Dec 12 2015, In : BMC Endocrine Disorders. 15, 1, 36.

Research output: Contribution to journalArticle

Open Access
Diabetic Cardiomyopathies
Peroxisome Proliferators
High Fat Diet
Fingers
Muscles
14 Citations (Scopus)

Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes

Banerjee, R., He, J., Spaniel, C., Quintana, M. T., Wang, Z., Bain, J. R., Newgard, C. B., Muehlbauer, M. J. & Willis, M., Apr 1 2015, In : Metabolomics. 11, 2, p. 312-322 11 p.

Research output: Contribution to journalArticle

Metabolomics
Fingers
Muscle
Myocardium
Muscles
21 Citations (Scopus)

Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis

Banerjee, R., Bultman, S. J., Holley, D., Hillhouse, C., Bain, J. R., Newgard, C. B., Muehlbauer, M. J. & Willis, M., Oct 7 2015, In : Metabolomics. 11, 5, p. 1287-1301 15 p.

Research output: Contribution to journalArticle

Metabolomics
Glycogen
Cardiac Myocytes
Homeostasis
Glucose-6-Phosphate