Mu Wang

  • 5187 Citations
  • 39 h-Index
1993 …2019

Research output per year

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Publications

2019

Parkinson’s disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics

Wu, C. X., Liao, J., Park, Y., Reed, X., Engel, V. A., Hoang, N. C., Takagi, Y., Johnson, S. M., Wang, M., Federici, M., Jeremy Nichols, R., Sanishvili, R., Cookson, M. R. & Hoang, Q. Q., Apr 12 2019, In : Journal of Biological Chemistry. 294, 15, p. 5907-5913 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Attraction and Compaction of Migratory Breast Cancer Cells by Bone Matrix Proteins through Tumor-Osteocyte Interactions

Chen, A., Wang, L., Liu, S., Wang, Y., Liu, Y., Wang, M., Nakshatri, H., Li, B. Y. & Yokota, H., Dec 1 2018, In : Scientific reports. 8, 1, 5420.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer

Lai, X., Wang, M., McElyea, S. D., Sherman, S., House, M. & Korc, M., May 1 2017, In : Cancer Letters. 393, p. 86-93 8 p.

Research output: Contribution to journalArticle

96 Scopus citations

Phosphorylation of the bovine papillomavirus E2 protein on tyrosine regulates its transcription and replication functions

Culleton, S. P., Kanginakudru, S., DeSmet, M., Gilson, T., Xie, F., Wu, S. Y., Chiang, C. M., Qi, G., Wang, M. & Androphy, E. J., 2017, In : Journal of virology. 91, 2, e01854-16.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Carbamylation of the amino-terminal residue (Gly1) of mouse serum amyloid A promotes amyloid formation in a cell culture model

Kluve-Beckerman, B., Liepnieks, J. J., Benson, M., Lai, X., Qi, G. & Wang, M., Dec 1 2016, In : FEBS Letters. 590, 23, p. 4296-4307 12 p.

Research output: Contribution to journalLetter

4 Scopus citations

Metabolic and molecular regulation of dietary polyunsaturated fatty acids on prostate cancer

Zhao, H., Pflug, B., Lai, X. & Wang, M., Mar 1 2016, In : Proteomics - Clinical Applications. 10, 3, p. 267-279 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pyruvate dehydrogenase alpha 1 as a target of omega-3 polyunsaturated fatty acids in human prostate cancer through a global phosphoproteomic analysis

Zhao, H., Pflug, B., Lai, X. & Wang, M., Sep 1 2016, In : Proteomics. 16, 17, p. 2419-2431 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures

Schweitzer, K. S., Chen, S. X., Law, S., Van Demark, M., Poirier, C., Justice, M. J., Hubbard, W. C., Kim, E. S., Lai, X., Wang, M., Kranz, W. D., Carroll, C. J., Ray, B. D., Bittman, R., Goodpaster, J. & Petrache, I., Jul 15 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 2, p. L175-L187

Research output: Contribution to journalArticle

115 Scopus citations

Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress

Gaji, R. Y., Johnson, D. E., Treeck, M., Wang, M., Hudmon, A. & Arrizabalaga, G., Nov 1 2015, In : PLoS Pathogens. 11, 11, e1005268.

Research output: Contribution to journalArticle

30 Scopus citations
2014

Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain

Liao, J., Wu, C. X., Burlak, C., Zhang, S., Sahm, H., Wang, M., Zhang, Z. Y., Vogel, K. W., Federici, M., Riddle, S. M., Nichols, R. J., Liu, D., Cookson, M. R., Stone, T. A. & Hoang, Q. Q., Mar 18 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 11, p. 4055-4060 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Pathway-based biomarkers for breast cancer in proteomics

Zhang, F., Deng, Y., Wang, M., Cui, L. & Drabier, R., Jan 1 2014, In : Cancer Informatics. 13, Suppl 5, p. 101-108 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Proteomic analysis of fibroblastema formation in regenerating hind limbs of Xenopus laevis froglets and comparison to axolotl

Rao, N., Song, F., Jhamb, D., Wang, M., Milner, D. J., Price, N. M., Belecky-Adams, T. L., Palakal, M. J., Cameron, J. A., Li, B., Chen, X. & Stocum, D. L., Jul 25 2014, In : BMC Developmental Biology. 14, 1, 32.

Research output: Contribution to journalArticle

23 Scopus citations
2013

A neural network approach to multi-biomarker panel discovery by high-throughput plasma proteomics profiling of breast cancer

Zhang, F., Chen, J., Wang, M. & Drabier, R., Dec 20 2013, In : BMC Proceedings. 7, S10.

Research output: Contribution to journalArticle

5 Scopus citations

Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in liquid chromatography-multiple reaction monitoring-MS (LC-MRM-MS)

Abbatiello, S. E., Mani, D. R., Schilling, B., MacLean, B., Zimmerman, L. J., Feng, X., Cusack, M. P., Sedransk, N., Hall, S. C., Addona, T., Allen, S., Dodder, N. G., Ghosh, M., Held, J. M., Hedrick, V., Inerowicz, H. D., Jackson, A., Keshishian, H., Kim, J. W., Lyssand, J. S. & 27 others, Riley, C. P., Rudnick, P., Sadowski, P., Shaddox, K., Smith, D., Tomazela, D., Wahlander, A., Waldemarson, S., Whitwell, C. A., You, J., Zhang, S., Kinsinger, C. R., Mesri, M., Rodriguez, H., Borchers, C. H., Buck, C., Fisher, S. J., Gibson, B. W., Liebler, D., MacCoss, M., Neubert, T. A., Paulovich, A., Regnier, F., Skates, S. J., Tempst, P., Wang, M. & Carr, S. A., Sep 2013, In : Molecular and Cellular Proteomics. 12, 9, p. 2623-2639 17 p.

Research output: Contribution to journalArticle

73 Scopus citations

Dual-function biomarkers for detection of breast cancer and its cancer type: Invasive versus non-invasive

Zhang, F., Liu, T., Wang, M. & Drabier, R., 2013, Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013. p. 345-348 4 p. 6732516. (Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Integrated Analysis of Global mRNA and Protein Expression Data in HEK293 Cells Overexpressing PRL-1

Dumaual, C. M., Steere, B. A., Walls, C. D., Wang, M., Zhang, Z. Y. & Randall, S. K., Sep 3 2013, In : PloS one. 8, 9, e72977.

Research output: Contribution to journalArticle

8 Scopus citations

Novel alternative splicing isoform biomarkers identification from high-throughput plasma proteomics profiling of breast cancer

Zhang, F., Wang, M., Michael, T. & Drabier, R., Dec 9 2013, In : BMC Systems Biology. 7, SUPPL 5, S8.

Research output: Contribution to journalArticle

12 Scopus citations

Phosphatase of regenerating liver 3 (prl3) provokes a tyrosine phosphoproteome to drive prometastatic signal transduction

Walls, C. D., Iliuk, A., Bai, Y., Wang, M., Tao, A. & Zhang, Z. Y., Dec 1 2013, In : Molecular and Cellular Proteomics. 12, 12, p. 3759-3777 19 p.

Research output: Contribution to journalArticle

19 Scopus citations

Proteomic analysis of immediate-early response plasma proteins after 70% and 90% partial hepatectomy

Kumar, S., Zou, Y., Bao, Q., Wang, M. & Dai, G., Aug 1 2013, In : Hepatology Research. 43, 8, p. 876-889 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Sepsis: An integrated clinico-metabolomic model improves prediction of death in sepsis

Langley, R. J., Tsalik, E. L., Van Velkinburgh, J. C., Glickman, S. W., Rice, B. J., Wang, C., Chen, B., Carin, L., Suarez, A., Mohney, R. P., Freeman, D. H., Wang, M., You, J., Wulff, J., Will Thompson, J., Arthur Moseley, M., Reisinger, S., Edmonds, B. T., Grinnell, B., Nelson, D. R. & 18 others, Dinwiddie, D. L., Miller, N. A., Saunders, C. J., Soden, S. S., Rogers, A. J., Gazourian, L., Fredenburgh, L. E., Massaro, A. F., Baron, R. M., Choi, A. M. K., Ralph Corey, G., Ginsburg, G. S., Cairns, C. B., Otero, R. M., Fowler, V. G., Rivers, E. P., Woods, C. W. & Kingsmore, S. F., Jul 24 2013, In : Science translational medicine. 5, 195, 195ra95.

Research output: Contribution to journalArticle

202 Scopus citations
2012

Mass spectrometry for protein quantification in biomarker discovery

Wang, M. & You, J., Jan 2 2012, Functional Genomics: Methods and Protocols. Kaufmann, M. & Klinger, C. (eds.). p. 199-225 27 p. (Methods in Molecular Biology; vol. 815).

Research output: Chapter in Book/Report/Conference proceedingChapter

14 Scopus citations

Serum proteomic profiling in patients with drug-induced liver injury

Bell, L. N., Vuppalanchi, R., Watkins, P. B., Bonkovsky, H. L., Serrano, J., Fontana, R. J., Wang, M., Rochon, J. & Chalasani, N., Mar 1 2012, In : Alimentary Pharmacology and Therapeutics. 35, 5, p. 600-612 13 p.

Research output: Contribution to journalArticle

48 Scopus citations

The proteome of normal pancreatic juice

Doyle, C. J., Yancey, K., Pitt, H. A., Wang, M., Bemis, K., Yip-Schneider, M. T., Sherman, S. T., Lillemoe, K. D., Goggins, M. D. & Schmidt, C. M., Mar 1 2012, In : Pancreas. 41, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2011

Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes

Shao, C. H., Capek, H. L., Patel, K. P., Wang, M., Tang, K., DeSouza, C., Nagai, R., Mayhan, W., Periasamy, M. & Bidasee, K. R., Mar 1 2011, In : Diabetes. 60, 3, p. 947-959 13 p.

Research output: Contribution to journalArticle

51 Scopus citations

Incrimination of heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) as a candidate sensor of physiological folate deficiency

Tang, Y. S., Khan, R. A., Zhang, Y., Xiao, S., Wang, M., Hansen, D. K., Jayaram, H. N. & Antony, A. C., Nov 11 2011, In : Journal of Biological Chemistry. 286, 45, p. 39100-39115 16 p.

Research output: Contribution to journalArticle

22 Scopus citations

Proteomic analysis of endothelial cold-adaptation

Zieger, M. A. J., Gupta, M. P. & Wang, M., Dec 22 2011, In : BMC genomics. 12, 630.

Research output: Contribution to journalArticle

6 Scopus citations

Utility of formalin-fixed, paraffin-embedded liver biopsy specimens for global proteomic analysis in nonalcoholic steatohepatitis

Bell, L. N., Saxena, R., Mattar, S. G., You, J., Wang, M. & Chalasani, N., Aug 1 2011, In : Proteomics - Clinical Applications. 5, 7-8, p. 397-404 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2010

A GMM-IG framework for selecting genes as expression panel biomarkers

Wang, M. & Chen, J. Y., Feb 1 2010, In : Artificial Intelligence in Medicine. 48, 2-3, p. 75-82 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Breast cancer plasma protein biomarker discovery by coupling LC-MS/MS proteomics and systems biology

Zhang, F., Wang, M. & Chen, J. Y., Oct 25 2010, 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010. p. 463-465 3 p. (2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Carbonylation of myosin heavy chains in rat heart during diabetes

Shao, C. H., Rozanski, G. J., Nagai, R., Stockdale, F. E., Patel, K. P., Wang, M., Singh, J., Mayhan, W. G. & Bidasee, K. R., Jul 1 2010, In : Biochemical Pharmacology. 80, 2, p. 205-217 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance

Paulovich, A. G., Billheimer, D., Ham, A. J. L., Vega-Montoto, L., Rudnick, P. A., Tabb, D. L., Wang, P., Blackman, R. K., Bunk, D. M., Cardasis, H. L., Clauser, K. R., Kinsinger, C. R., Schilling, B., Tegeler, T. J., Variyath, A. M., Wang, M., Whiteaker, J. R., Zimmerman, L. J., Fenyo, D., Carr, S. A. & 10 others, Fisher, S. J., Gibson, B. W., Mesri, M., Neubert, T. A., Regnier, F. E., Rodriguez, H., Spiegelman, C., Stein, S. E., Tempst, P. & Liebler, D. C., Feb 2010, In : Molecular and Cellular Proteomics. 9, 2, p. 242-254 13 p.

Research output: Contribution to journalArticle

125 Scopus citations

Knock-down of superoxide dismutase 1 sensitizes cisplatin-resistant human ovarian cancer cells

Kim, J. W., Sahm, H., You, J. & Wang, M., Jul 1 2010, In : Anticancer Research. 30, 7, p. 2577-2581 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Multi-dimensional liquid chromatography in proteomics-A review

Zhang, X., Fang, A., Riley, C. P., Wang, M., Regnier, F. E. & Buck, C., Apr 1 2010, In : Analytica Chimica Acta. 664, 2, p. 101-113 13 p.

Research output: Contribution to journalReview article

112 Scopus citations

Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses

Rudnick, P. A., Clauser, K. R., Kilpatrick, L. E., Tchekhovskoi, D. V., Neta, P., Blonder, N., Billheimer, D. D., Blackman, R. K., Bunk, D. M., Cardasis, H. L., Ham, A. J. L., Jaffe, J. D., Kinsinger, C. R., Mesri, M., Neubert, T. A., Schilling, B., Tabb, D. L., Tegeler, T. J., Vega-Montoto, L., Variyath, A. M. & 14 others, Wang, M., Wang, P., Whiteaker, J. R., Zimmerman, L. J., Carr, S. A., Fisher, S. J., Gibson, B. W., Paulovich, A. G., Regnier, F. E., Rodriguez, H., Spiegelman, C., Tempst, P., Liebler, D. C. & Stein, S. E., Feb 2010, In : Molecular and Cellular Proteomics. 9, 2, p. 225-241 17 p.

Research output: Contribution to journalArticle

140 Scopus citations

Personalized medicine in oncology: Tailoring the right drug to the right patient

Jiang, Y. & Wang, M., Aug 1 2010, In : Biomarkers in Medicine. 4, 4, p. 523-533 11 p.

Research output: Contribution to journalReview article

28 Scopus citations

Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry

Tabb, D. L., Vega-Montoto, L., Rudnick, P. A., Variyath, A. M., Ham, A. J. L., Bunk, D. M., Kilpatrick, L. E., Billheimer, D. D., Blackman, R. K., Cardasis, H. L., Carr, S. A., Clauser, K. R., Jaffe, J. D., Kowalski, K. A., Neubert, T. A., Regnier, F. E., Schilling, B., Tegeler, T. J., Wang, M., Wang, P. & 12 others, Whiteaker, J. R., Zimmerman, L. J., Fisher, S. J., Gibson, B. W., Kinsinger, C. R., Mesri, M., Rodriguez, H., Stein, S. E., Tempst, P., Paulovich, A. G., Liebler, D. C. & Spiegelman, C., Feb 5 2010, In : Journal of Proteome Research. 9, 2, p. 761-776 16 p.

Research output: Contribution to journalArticle

300 Scopus citations
38 Scopus citations

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease

Bell, L. N., Theodorakis, J. L., Vuppalanchi, R., Saxena, R., Bemis, K. G., Wang, M. & Chalasani, N., Jan 1 2010, In : Hepatology. 51, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

Targeted quantitative analysis of superoxide dismutase 1 in cisplatin-sensitive and cisplatin-resistant human ovarian cancer cells

Kim, J. W., Nie, B., Sahm, H., Brown, D. P. G., Tegeler, T., You, J. S. & Wang, M., Mar 1 2010, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 878, 7-8, p. 700-704 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2009

Comparison of an Enzyme Immunoassay Versus Mass Spectrometry-based Assay for the Quantitative Determination of the Procollagen Type I N-terminal Propeptide in Rat Serum

Dzieciatkowska, M., Copeland, M., You, J., Wery, J. P. & Wang, M., Dec 1 2009, In : Proteomics Insights. 2, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: A proteomics study

McBride, W. J., Schultz, J. A., Kimpel, M. W., McClintick, J. N., Wang, M., You, J. & Rodd, Z. A., Apr 1 2009, In : Pharmacology Biochemistry and Behavior. 92, 2, p. 304-313 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Erratum: Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma( Nature Biotechnology (2009) 27 (633-641))

Addona, T. A., Abbatiello, S. E., Schilling, B., Skates, S. J., Mani, D. R., Bunk, D. M., Spiegelman, C. H., Zimmerman, L. J., Ham, A. J. L., Keshishian, H., Hall, S. C., Allen, S., Blackman, R. K., Borchers, C. H., Buck, C., Cardasis, H. L., Cusack, M. P., Dodder, N. G., Gibson, B. W., Held, J. M. & 29 others, Hiltke, T., Jackson, A., Johansen, E. B., Kinsinger, C. R., Li, J., Mesri, M., Neubert, T. A., Niles, R. K., Pulsipher, T. C., Ransohoff, D., Rodriguez, H., Rudnick, P. A., Smith, D., Tabb, D. L., Tegeler, T. J., Variyath, A. M., Vega-Montoto, L. J., Wahlander, S., Waldemarson, S., Wang, M., Whiteaker, J. R., Zhao, L., Anderson, N. L., Fisher, S. J., Liebler, D. C., Paulovich, A. G., Regnier, F. E., Tempst, P. & Carr, S. A., Sep 1 2009, In : Nature Biotechnology. 27, 9, 1 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Intrinsic subtype-associated changes in the plasma proteome in breast cancer

Nakshatri, H., Qi, G., You, J., Kerry, B., Schneider, B., Zon, R., Buck, C., Regnier, F. & Wang, M., Dec 1 2009, In : Proteomics - Clinical Applications. 3, 11, p. 1305-1313 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

LC/MS-based quantitative proteomic analysis of paraffin-embedded archival melanomas reveals potential proteomic biomarkers associated with metastasis

Huang, S. K., Darfler, M. M., Nicholl, M. B., You, J., Bemis, K. G., Tegeler, T. J., Wang, M., Wery, J. P., Chong, K. K., Nguyen, L., Scolyer, R. A. & Hoon, D. S. B., Feb 16 2009, In : PLoS ONE. 4, 2, e4430.

Research output: Contribution to journalArticle

53 Scopus citations

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

Addona, T. A., Abbatiello, S. E., Schilling, B., Skates, S. J., Mani, D. R., Bunk, D. M., Spiegelman, C. H., Zimmerman, L. J., Ham, A. J. L., Keshishian, H., Hall, S. C., Allen, S., Blackman, R. K., Borchers, C. H., Buck, C., Cardasis, H. L., Cusack, M. P., Dodder, N. G., Gibson, B. W., Held, J. M. & 29 others, Hiltke, T., Jackson, A., Johansen, E. B., Kinsinger, C. R., Li, J., Mesri, M., Neubert, T. A., Niles, R. K., Pulsipher, T. C., Ransohoff, D., Rodriguez, H., Rudnick, P. A., Smith, D., Tabb, D. L., Tegeler, T. J., Variyath, A. M., Vega-Montoto, L. J., Wahlander, Å., Waldemarson, S., Wang, M., Whiteaker, J. R., Zhao, L., Anderson, N. L., Fisher, S. J., Liebler, D. C., Paulovich, A. G., Regnier, F. E., Tempst, P. & Carr, S. A., Jul 1 2009, In : Nature Biotechnology. 27, 7, p. 633-641 9 p.

Research output: Contribution to journalArticle

780 Scopus citations

Proteomic analysis of blastema formation in regenerating axolotl limbs

Rao, N., Jhamb, D., Milner, D. J., Li, B., Song, F., Wang, M., Voss, S. R., Palakal, M., King, M. W., Saranjami, B., Nye, H. L. D., Cameron, J. A. & Stocum, D. L., Nov 30 2009, In : BMC Biology. 7, 83.

Research output: Contribution to journalArticle

84 Scopus citations

Proteomic analysis of human aqueous humor using multidimensional protein identification technology.

Richardson, M. R., Price, M. O., Price, F. W., Pardo, J. C., Grandin, J. C., You, J., Wang, M. & Yoder, M. C., 2009, In : Molecular vision. 15, p. 2740-2750 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Targeting superoxide dismutase 1 to overcome cisplatin resistance in human ovarian cancer

Brown, D. P. G., Chin-Sinex, H., Nie, B., Mendonca, M. S. & Wang, M., Mar 1 2009, In : Cancer Chemotherapy and Pharmacology. 63, 4, p. 723-730 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2008

Identification of FANCA interacting proteins in mammalian cells using tandem affinity purification and mass spectrometry

Conner, S. L. & Wang, M., Dec 1 2008, In : Scientific Research and Essays. 3, 4, p. 143-153 11 p.

Research output: Contribution to journalArticle

3 Scopus citations