Nadia Carlesso

  • 4818 Citations
  • 30 h-Index
1990 …2019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1990 2019

  • 4818 Citations
  • 30 h-Index
  • 59 Article
  • 1 Conference contribution
  • 1 Comment/debate
Filter
Article
2019

Targeting cell membrane HDM2: A novel therapeutic approach for acute myeloid leukemia

Wang, H., Zhao, D., Nguyen, L. X., Wu, H., Li, L., Dong, D., Troadec, E., Zhu, Y., Hoang, D. H., Stein, A. S., Al Malki, M., Aldoss, I., Lin, A., Ghoda, L. Y., McDonald, T., Pichiorri, F., Carlesso, N., Kuo, Y. H., Zhang, B., Jin, J. & 1 others, Marcucci, G., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Cell Membrane
Membranes
Cadherins
Hematopoietic Stem Cells

Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia

Zhu, Y., He, X., Lin, Y. C., Dong, H., Zhang, L., Chen, X., Wang, Z., Shen, Y., Li, M., Wang, H., Sun, J., Nguyen, L. X., Zhang, H., Jiang, W., Yang, Y., Chen, J., Mu¨schen, M., Chen, C. W., Konopleva, M. Y., Sun, W. & 5 others, Jin, J., Carlesso, N., Marcucci, G., Luo, Y. & Li, L., Oct 10 2019, In : Blood. 134, 15, p. 1257-1268 12 p.

Research output: Contribution to journalArticle

fms-Like Tyrosine Kinase 3
Methylation
Receptor Protein-Tyrosine Kinases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Maintenance
2018
47 Citations (Scopus)

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion

Kumar, B., Garcia, M., Weng, L., Jung, X., Murakami, J. L., Hu, X., McDonald, T., Lin, A., Kumar, A. R., Digiusto, D. L., Stein, A. S., Pullarkat, V. A., Hui, S. K., Carlesso, N., Kuo, Y. H., Bhatia, R., Marcucci, G. & Chen, C. C., Mar 1 2018, In : Leukemia. 32, 3, p. 575-587 13 p.

Research output: Contribution to journalArticle

Exosomes
Acute Myeloid Leukemia
Leukemia
Bone Marrow
Hematopoiesis
14 Citations (Scopus)

Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia

Zhang, B., Nguyen, L. X. T., Li, L., Zhao, D., Kumar, B., Wu, H., Lin, A., Pellicano, F., Hopcroft, L., Su, Y. L., Copland, M., Holyoake, T. L., Kuo, C. J., Bhatia, R., Snyder, D. S., Ali, H., Stein, A. S., Brewer, C., Wang, H., McDonald, T. & 12 others, Swiderski, P., Troadec, E., Chen, C. C., Dorrance, A., Pullarkat, V., Yuan, Y. C., Perrotti, D., Carlesso, N., Forman, S. J., Kortylewski, M., Kuo, Y. H. & Marcucci, G., May 1 2018, In : Nature Medicine. 24, 4, p. 450-462 13 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Stem cells
Bone
Leukemia
Bone Marrow
9 Citations (Scopus)

Copper 64-labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

Caserta, E., Chea, J., Minnix, M., Viola, D., Vonderfecht, S., Yazaki, P., Crow, D., Khalife, J., Sanchez, J. F., Palmer, J. M., Hui, S., Carlesso, N., Keats, J., Kim, Y., Buettner, R., Marcucci, G., Rosen, S., Shively, J., Colcher, D., Krishnan, A. & 1 others, Pichiorri, F., Feb 15 2018, In : Blood. 131, 7, p. 741-745 5 p.

Research output: Contribution to journalArticle

Positron emission tomography
Multiple Myeloma
Tomography
Copper
Imaging techniques
10 Citations (Scopus)

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function

Sun, J., He, X., Zhu, Y., Ding, Z., Dong, H., Feng, Y., Du, J., Wang, H., Wu, X., Zhang, L., Yu, X., Lin, A., McDonald, T., Zhao, D., Wu, H., Hua, W. K., Zhang, B., Feng, L., Tohyama, K., Bhatia, R. & 13 others, Oberdoerffer, P., Chung, Y. J., Aplan, P. D., Boultwood, J., Pellagatti, A., Khaled, S., Kortylewski, M., Pichiorri, F., Kuo, Y. H., Carlesso, N., Marcucci, G., Jin, H. & Li, L., Sep 6 2018, In : Cell Stem Cell. 23, 3, p. 355-369.e9

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Hematopoietic Stem Cells
Stem Cells
Maintenance
2017
Genetic Models
Myeloid Cells
Stem cells
Bone Marrow Cells
Microscopic examination
12 Citations (Scopus)

Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells

Singh, P., Hoggatt, J., Kamocka, M., Mohammad, K., Saunders, M. R., Li, H., Speth, J., Carlesso, N., Guise, T. & Pelus, L., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4527-4540 14 p.

Research output: Contribution to journalArticle

Neuropeptide Y
Hematopoietic Stem Cells
Blood Vessels
Endothelial Cells
Hematopoietic Stem Cell Mobilization
6 Citations (Scopus)

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors

Kobayashi, M., Nabinger, S. C., Bai, Y., Yoshimoto, M., Gao, R., Chen, S., Yao, C., Dong, Y., Zhang, L., Rodriguez, S., Yashiro-Ohtani, Y., Pear, W. S., Carlesso, N., Yoder, M., Kapur, R., Kaplan, M., Daniel Lacorazza, H., Zhang, Z-Y. & Liu, Y., Apr 1 2017, In : Stem Cells. 35, 4, p. 1053-1064 12 p.

Research output: Contribution to journalArticle

Protein Tyrosine Phosphatases
Hematopoietic Stem Cells
T-Lymphocytes
Cell Differentiation
Stem Cell Factor
2016
64 Citations (Scopus)
Osteocytes
Tumor Microenvironment
Multiple Myeloma
Bone Marrow
Cell Proliferation
14 Citations (Scopus)

S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance

Ghosh, J., Kobayashi, M., Ramdas, B., Chatterjee, A., Ma, P., Mali, R. S., Carlesso, N., Liu, Y., Plas, D. R., Chan, R. & Kapur, R., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2621-2625 5 p.

Research output: Contribution to journalArticle

Ribosomal Protein S6 Kinases
Hematopoietic Stem Cells
Leukemia
Maintenance
Oncogene Fusion
24 Citations (Scopus)

Sepsis induces hematopoietic stem cell exhaustion and myelosuppression through distinct contributions of TRIF and MYD88

Zhang, H., Rodriguez, S., Wang, L., Wang, S., Serezani, H., Kapur, R., Cardoso, A. A. & Carlesso, N., Jun 14 2016, In : Stem Cell Reports. 6, 6, p. 940-956 17 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Toll-Like Receptor 4
Sepsis
Chemical activation
28 Citations (Scopus)

Structural and functional characterization of endothelial microparticles released by cigarette smoke

Serban, K. A., Rezania, S., Petrusca, D., Poirier, C., Cao, D., Justice, M. J., Patel, M., Tsvetkova, I., Kamocki, K., Mikosz, A., Schweitzer, K. S., Jacobson, S., Cardoso, A., Carlesso, N., Hubbard, W. C., Kechris, K., Dragnea, B., Berdyshev, E. V., McClintock, J. & Petrache, I., Aug 17 2016, In : Scientific Reports. 6, 31596.

Research output: Contribution to journalArticle

Smoke
Tobacco Products
Sphingomyelin Phosphodiesterase
Ceramides
MicroRNAs
2015
12 Citations (Scopus)

Notch ligand Delta-like 1 promotes invivo vasculogenesis in human cord blood-derived endothelial colony forming cells

Kim, H., Huang, L., Critser, P. J., Yang, Z., Chan, R., Wang, L., Carlesso, N., Voytik-Harbin, S. L., Bernstein, I. D. & Yoder, M., 2015, In : Cytotherapy. 17, 5, p. 579-592 14 p.

Research output: Contribution to journalArticle

Fetal Blood
Ligands
Stromal Cells
Blood Vessels
Notch Receptors
98 Citations (Scopus)

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

Tu, X., Delgado-Calle, J., Condon, K. W., Maycas, M., Zhang, H., Carlesso, N., Taketo, M. M., Burr, D., Plotkin, L. & Bellido, T., Feb 3 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 5, p. E478-E486

Research output: Contribution to journalArticle

Osteocytes
Catenins
Bone and Bones
Osteoblasts
Osteoclasts
2014
30 Citations (Scopus)

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

Chitteti, B. R., Kobayashi, M., Cheng, Y., Zhang, H., Poteat, B. A., Broxmeyer, H., Pelus, L., Hanenberg, H., Zollman, A., Kamocka, M., Carlesso, N., Cardoso, A. A., Kacena, M. & Srour, E., Jul 24 2014, In : Blood. 124, 4, p. 519-529 11 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Hematopoietic Stem Cells
Stem cells
Osteoblasts
Chimerism
118 Citations (Scopus)

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity

Bi, P., Shan, T., Liu, W., Yue, F., Yang, X., Liang, X. R., Wang, J., Li, J., Carlesso, N., Liu, X. & Kuang, S., 2014, In : Nature Medicine. 20, 8, p. 911-918 8 p.

Research output: Contribution to journalArticle

White Adipose Tissue
Obesity
Tissue
Energy Metabolism
Chemical activation
102 Citations (Scopus)

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner

Wang, L., Zhang, H., Rodriguez, S., Cao, L., Parish, J., Mumaw, C., Zollman, A., Kamocka, M., Mu, J., Chen, D. Z., Srour, E., Chitteti, B. R., HogenEsch, H., Tu, X., Bellido, T., Boswell, H., Manshouri, T., Verstovsek, S., Yoder, M., Kapur, R. & 2 others, Cardoso, A. A. & Carlesso, N., Jul 3 2014, In : Cell Stem Cell. 15, 1, p. 51-65 15 p.

Research output: Contribution to journalArticle

Hematopoiesis
Bone Marrow
Cytokines
Myeloproliferative Disorders
MicroRNAs
2013
45 Citations (Scopus)

Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity

Chen, H., Zhang, W., Sun, X., Yoshimoto, M., Chen, Z., Zhu, W., Liu, J., Shen, Y., Yong, W., Li, D., Zhang, J., Lin, Y., Li, B., VanDusen, N. J., Snider, P., Schwartz, R. J., Conway, S., Field, L., Yoder, M., Firulli, A. & 3 others, Carlesso, N., Towbin, J. A. & Shou, W., May 1 2013, In : Development (Cambridge). 140, 9, p. 1946-1957 12 p.

Research output: Contribution to journalArticle

Myocardium
Endothelial Cells
Tacrolimus Binding Protein 1A
Peptidylprolyl Isomerase
Endocardium
2012
74 Citations (Scopus)

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence

Yoshimoto, M., Porayette, P., Glosson, N. L., Conway, S., Carlesso, N., Cardoso, A. A., Kaplan, M. & Yoder, M., Jun 14 2012, In : Blood. 119, 24, p. 5706-5714 9 p.

Research output: Contribution to journalArticle

Yolk Sac
T-cells
T-Lymphocytes
Thymus
Embryonic Structures
8 Citations (Scopus)

Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms

Hu, P., Carlesso, N., Xu, M., Liu, Y., Nebreda, A. R., Takemoto, C. & Kapur, R., Jun 8 2012, In : Journal of Biological Chemistry. 287, 24, p. 20258-20269 12 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Chemotaxis
Mast Cells
Cell Differentiation
Microphthalmia-Associated Transcription Factor
37 Citations (Scopus)

Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21 Cip1 expression and hampers tumour cell growth in vitro and in vivo

Raimondi, L., Ciarapica, R., De Salvo, M., Verginelli, F., Gueguen, M., Martini, C., De Sio, L., Cortese, G., Locatelli, M., Dang, T. P., Carlesso, N., Miele, L., Stifani, S., Limon, I., Locatelli, F. & Rota, R., May 2012, In : Cell Death and Differentiation. 19, 5, p. 871-881 11 p.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Cell Differentiation
Phosphorylation
Growth
Neoplasms
47 Citations (Scopus)

Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells

Hutter, C., Kauer, M., Simonitsch-Klupp, I., Jug, G., Schwentner, R., Leitner, J., Bock, P., Steinberger, P., Bauer, W., Carlesso, N., Minkov, M., Gadner, H., Stingl, G., Kovar, H. & Kriehuber, E., Dec 20 2012, In : Blood. 120, 26, p. 5199-5208 10 p.

Research output: Contribution to journalArticle

Langerhans Cell Histiocytosis
Dendritic Cells
Langerhans Cells
Matrix Metalloproteinase 12
Monocytes
9 Citations (Scopus)

P38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals

Hu, P., Nebreda, A. R., Liu, Y., Carlesso, N., Kaplan, M. & Kapur, R., Sep 28 2012, In : Journal of Biological Chemistry. 287, 40, p. 33215-33226 12 p.

Research output: Contribution to journalArticle

T-cells
T-Cell Antigen Receptor
T-Lymphocytes
Interleukin-4
Ovalbumin

When IFN interferes with cell fate

Carlesso, N., Feb 9 2012, In : Blood. 119, 6, p. 1327-1329 3 p.

Research output: Contribution to journalArticle

2011
22 Citations (Scopus)

Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells

Cheng, Y. H., Chitteti, B. R., Streicher, D. A., Morgan, J. A., Rodriguez-Rodriguez, S., Carlesso, N., Srour, E. & Kacena, M., May 2011, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 26, 5, p. 1111-1121 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Osteoblasts
Coculture Techniques
Chimerism
Hematopoiesis
32 Citations (Scopus)

Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors

Batista, A., Barata, J. T., Raderschall, E., Sallan, S. E., Carlesso, N., Nadler, L. M. & Cardoso, A. A., Apr 2011, In : Experimental Hematology. 39, 4, p. 457-472 16 p.

Research output: Contribution to journalArticle

T-Cell Leukemia
Sirolimus
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pharmaceutical Preparations
Interleukin-7
28 Citations (Scopus)

The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs

Rodriguez, S., Wang, L., Mumaw, C., Srour, E., Lo Celso, C., Nakayama, K. I. & Carlesso, N., Jun 16 2011, In : Blood. 117, 24, p. 6509-6519 11 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Regeneration
Cell Cycle
Homeostasis
Cells
2010
94 Citations (Scopus)

Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function

Chitteti, B. R., Cheng, Y. H., Poteat, B., Rodriguez-Rodriguez, S., Goebel, W., Carlesso, N., Kacena, M. & Srour, E., Apr 22 2010, In : Blood. 115, 16, p. 3239-3248 10 p.

Research output: Contribution to journalArticle

Osteoblasts
Hematopoietic Stem Cells
Bone
Bone Marrow
Stromal Cells
44 Citations (Scopus)

Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function

Chitteti, B. R., Cheng, Y. H., Streicher, D. A., Rodriguez-Rodriguez, S., Carlesso, N., Srour, E. & Kacena, M., Oct 1 2010, In : Journal of Cellular Biochemistry. 111, 2, p. 284-294 11 p.

Research output: Contribution to journalArticle

Osteoblasts
Cell proliferation
Hematopoietic Stem Cells
Cells
Cell Proliferation
53 Citations (Scopus)

Stem cell regulatory niches and their role in normal and malignant hematopoiesis

Carlesso, N. & Cardoso, A. A., Jul 2010, In : Current Opinion in Hematology. 17, 4, p. 281-286 6 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Hematopoiesis
Hematopoietic Stem Cells
Bone Marrow
Leukemia
2009
26 Citations (Scopus)

Bone Marrow-Derived B Cells Preserve Ventricular Function After Acute Myocardial Infarction

Goodchild, T. T., Robinson, K. A., Pang, W., Tondato, F., Cui, J., Arrington, J., Godwin, L., Ungs, M., Carlesso, N., Weich, N., Poznansky, M. C. & Chronos, N. A. F., Oct 2009, In : JACC: Cardiovascular Interventions. 2, 10, p. 1005-1016 12 p.

Research output: Contribution to journalArticle

Ventricular Function
B-Lymphocytes
Bone Marrow Cells
Bone Marrow
Myocardial Infarction
74 Citations (Scopus)

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis

Rodriguez, S., Chora, A., Goumnerov, B., Mumaw, C., Goebel, W., Fernandez, L., Baydoun, H., HogenEsch, H., Dombkowski, D. M., Karlewicz, C. A., Rice, S., Rahme, L. G. & Carlesso, N., Nov 5 2009, In : Blood. 114, 19, p. 4064-4076 13 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Sepsis
Neutropenia
Neutrophils
2008
38 Citations (Scopus)

Tumor necrosis factor-α and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation

Fernandez, L., Rodriguez, S., Huang, H., Chora, A., Fernandes, J., Mumaw, C., Cruz, E., Pollok, K., Cristina, F., Price, J. E., Ferkowicz, M. J., Scadden, D. T., Clauss, M., Cardoso, A. A. & Carlesso, N., May 2008, In : Experimental Hematology. 36, 5

Research output: Contribution to journalArticle

Endothelial Cells
Tumor Necrosis Factor-alpha
Bone Marrow
Bone Marrow Cells
Inflammation
2007
141 Citations (Scopus)

Delta-like 4 induces Notch signaling in macrophages: Implications for inflammation

Fung, E., Tang, S. M. T., Canner, J. P., Morishige, K., Arboleda-Velasquez, J. F., Cardoso, A. A., Carlesso, N., Aster, J. C. & Aikawa, M., Jun 2007, In : Circulation. 115, 23, p. 2948-2956 9 p.

Research output: Contribution to journalArticle

Macrophages
Inflammation
Nitric Oxide Synthase Type II
Atherosclerotic Plaques
Notch1 Receptor
2006
21 Citations (Scopus)

Molecular and functional evidence for activity of murine IL-7 on human lymphocytes

Barata, J. T., Silva, A., Abecasis, M., Carlesso, N., Cumano, A. & Cardoso, A. A., Sep 2006, In : Experimental Hematology. 34, 9, p. 1132-1141 10 p.

Research output: Contribution to journalArticle

Interleukin-7
Lymphocytes
Aptitude
Human Development
T-Lymphocytes
2005
141 Citations (Scopus)

Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27Kip1 degradation

Sarmento, L. M., Huang, H., Limon, A., Gordon, W., Fernandes, J., Tavares, M. J., Miele, L., Cardoso, A. A., Classon, M. & Carlesso, N., Jul 4 2005, In : Journal of Experimental Medicine. 202, 1, p. 157-168 12 p.

Research output: Contribution to journalArticle

S-Phase Kinase-Associated Proteins
Cyclin-Dependent Kinases
Cell Cycle
Cyclin-Dependent Kinase 2
Notch Receptors
2004
64 Citations (Scopus)

Notch-1 Regulates Cell Death Independently of Differentiation in Murine Erythroleukemia Cells Through Multiple Apoptosis and Cell Cycle Pathways

Jang, M. S., Miao, H., Carlesso, N., Shelly, L., Zlobin, A., Darack, N., Qin, J. Z., Nickoloff, B. J. & Miele, L., Jun 2004, In : Journal of Cellular Physiology. 199, 3, p. 418-433 16 p.

Research output: Contribution to journalArticle

Leukemia, Erythroblastic, Acute
Cell death
Cell Cycle
Cell Death
Chemical activation
2003
19 Citations (Scopus)

Myeloid Expression of Cytochrome P450 4F3 Is Determined by a Lineage-specific Alternative Promoter

Christmas, P., Carlesso, N., Shang, H., Cheng, S. M., Weber, B. M., Preffer, F. I., Scadden, D. T. & Soberman, R. J., Jul 4 2003, In : Journal of Biological Chemistry. 278, 27, p. 25133-25142 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Myeloid Cells
Exons
Protein Isoforms
Genes
2002
300 Citations (Scopus)

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome

Stier, S., Cheng, T., Dombkowski, D., Carlesso, N. & Scadden, D. T., Apr 1 2002, In : Blood. 99, 7, p. 2369-2378 10 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Stem Cells
Chemical activation
Notch1 Receptor
34 Citations (Scopus)

Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells

Wang, Z., Miura, N., Bonelli, A., Mole, P., Carlesso, N., Olson, D. P. & Scadden, D. T., Apr 15 2002, In : Blood. 99, 8, p. 2740-2747 8 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Bone
Cells
Ligands
Genistein
2001
111 Citations (Scopus)

Alternative Splicing Determines the Function of CYP4F3 by Switching Substrate Specificity

Christmas, P., Jones, J. P., Patten, C. J., Rock, D. A., Zheng, Y., Cheng, S. M., Weber, B. M., Carlesso, N., Scadden, D. T., Rettie, A. E. & Soberman, R. J., Oct 12 2001, In : Journal of Biological Chemistry. 276, 41, p. 38166-38172 7 p.

Research output: Contribution to journalArticle

Alternative Splicing
Substrate Specificity
Exons
Protein Isoforms
Hydroxylation
131 Citations (Scopus)

The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells

Ellisen, L. W., Carlesso, N., Cheng, T., Scadden, D. T. & Haber, D. A., Apr 17 2001, In : EMBO Journal. 20, 8, p. 1897-1909 13 p.

Research output: Contribution to journalArticle

Wilms Tumor
Hematopoietic Stem Cells
Tumors
Leukemia
Cells
2000
1534 Citations (Scopus)

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells

Lewin, M., Carlesso, N., Tung, C. H., Tang, X. W., Cory, D., Scadden, D. T. & Weissleder, R., 2000, In : Nature Biotechnology. 18, 4, p. 410-414 5 p.

Research output: Contribution to journalArticle

Stem cells
Nanoparticles
Peptides
Stem Cells
Recovery
1999
210 Citations (Scopus)

Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics

Carlesso, N., Aster, J. C., Sklar, J. & Scadden, D. T., Feb 1 1999, In : Blood. 93, 3, p. 838-848 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Cell Differentiation
Cell Cycle
Cells
Ligands
1997
6 Citations (Scopus)

Suppression of in vitro maintenance of non-promyelocytic myeloid leukemia clonogenic cells by all-trans retinoic acid: Modulating effects of dihydroxylated vitamin D3, α interferon and 'stem cell factor'

Ferrero, D., Carlesso, N., Bresso, P., Roux, V., Pregno, P., Gallo, E. & Pileri, A., Jan 1997, In : Leukemia Research. 21, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Myeloid Leukemia
Cholecalciferol
Tretinoin
Interferons
1996
99 Citations (Scopus)

Bcr/Abl expression stimulates integrin function in hematopoietic cell lines

Bazzoni, G., Carlesso, N., Griffin, J. D. & Hemler, M. E., Jul 15 1996, In : Journal of Clinical Investigation. 98, 2, p. 521-528 8 p.

Research output: Contribution to journalArticle

Integrin alpha5beta1
Integrins
Cell Line
bcr-abl Fusion Proteins
Cell Adhesion
Stem Cell Factor
Interleukin-3
Myeloid Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Tyrosine
48 Citations (Scopus)

PI 3-kinase activation in BCR/abl-transformed hematopoietic cells does not require interaction of p85 SH2 domains with p210 BCR/abl

Jain, S. K., Šuša, M., Keeler, M. L., Carlesso, N., Druker, B. & Varticovski, L., Sep 1 1996, In : Blood. 88, 5, p. 1542-1550 9 p.

Research output: Contribution to journalArticle

src Homology Domains
Phosphatidylinositol 3-Kinases
Chemical activation
abl Genes
Tyrosine
404 Citations (Scopus)
STAT Transcription Factors
Janus Kinases
Transformed Cell Line
Interleukin-3
Leukemia