Peter Roach

  • 11859 Citations
  • 56 h-Index
1970 …2021
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  • 14 Similar Profiles
Glycogen Synthase Medicine & Life Sciences
Glycogen Medicine & Life Sciences
Phosphorylation Chemical Compounds
Muscle Chemical Compounds
Rabbits Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences
Muscles Medicine & Life Sciences
Enzymes Medicine & Life Sciences

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NIH Grants 1977 2021

Lafora Disease
Glycogen
Glycogen Synthase
Therapeutics
Pharmaceutical Chemistry
Glycogen
Glycogen Synthase
Phosphorylation
Glucose
Glycogen Storage Disease
Glycogen
Glycogen Storage Disease Type II
Glycogen Storage Disease
Lysosomes
Wolff-Parkinson-White Syndrome
Lafora Disease
Glycogen
Phosphoric Monoester Hydrolases
Phosphorylation
Ubiquitin-Protein Ligases
chronic illness
training program
trainee
career
research interest

Publications 1970 2020

Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry

Young, L. E. A., Brizzee, C. O., Macedo, J. K. A., Murphy, R. D., Contreras, C. J., DePaoli-Roach, A. A., Roach, P. J., Gentry, M. S. & Sun, R. C., Feb 15 2020, In : Carbohydrate Polymers. 230, 115651.

Research output: Contribution to journalArticle

Carbohydrates
Mass spectrometry
Glucose
Glycogen
Phosphates

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Mayeuf-Louchart, A., Lancel, S., Sebti, Y., Pourcet, B., Loyens, A., Delhaye, S., Duhem, C., Beauchamp, J., Ferri, L., Thorel, Q., Boulinguiez, A., Zecchin, M., Dubois-Chevalier, J., Eeckhoute, J., Vaughn, L. T., Roach, P. J., Dani, C., Pederson, B. A., Vincent, S. D., Staels, B. & 1 others, Duez, H., Nov 5 2019, In : Cell Reports. 29, 6, p. 1410-1418.e6

Research output: Contribution to journalArticle

Open Access
Brown Adipocytes
Glycogen
Lipids
Stem cells
Induced Pluripotent Stem Cells
2 Citations (Scopus)

Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion

Brewer, M. K., Uittenbogaard, A., Austin, G. L., Segvich, D. M., DePaoli-Roach, A., Roach, P. J., McCarthy, J. J., Simmons, Z. R., Brandon, J. A., Zhou, Z., Zeller, J., Young, L. E. A., Sun, R. C., Pauly, J. R., Aziz, N. M., Hodges, B. L., McKnight, T. R., Armstrong, D. D. & Gentry, M. S., Oct 1 2019, In : Cell Metabolism. 30, 4, p. 689-705.e6

Research output: Contribution to journalArticle

Lafora Disease
Antibodies
Immunoglobulin Isotypes
Enzymes
Glycogen
19 Citations (Scopus)

Lafora disease offers a unique window into neuronal glycogen metabolism

Gentry, M. S., Guinovart, J. J., Minassian, B. A., Roach, P. & Serratosa, J. M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 19, p. 7117-7125 9 p.

Research output: Contribution to journalReview article

Lafora Disease
Glycogen
Metabolism
Glycogen Phosphorylase
Glycogen Synthase
10 Citations (Scopus)

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

Irimia, J. M., Meyer, C. M., Segvich, D. M., Surendran, S., De Paoli-Roach, A., Morral, N. & Roach, P., 2017, In : Journal of Biological Chemistry. 292, 25, p. 10455-10464 10 p.

Research output: Contribution to journalArticle

Liver Glycogen
Insulin Resistance
Insulin
Liver
Phosphorylation