Quyen Hoang

  • 1073 Citations
  • 13 h-Index
20032020
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Parkinson Disease Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences
Acyl-Butyrolactones Medicine & Life Sciences
Proteins Medicine & Life Sciences
Quorum Sensing Medicine & Life Sciences
Zinc Chemical Compounds
Protein Interaction Mapping Medicine & Life Sciences
Quenching Chemical Compounds

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NIH Grants 2012 2020

Leucine
Phosphotransferases
Parkinson Disease
GTP Phosphohydrolases
Mutation
GTP Phosphohydrolases
Mutation
Parkinson Disease
Phosphotransferases
Parkinson Disease Associated Proteins

Structure and conformational dynamics of alpha-synuclein

Hoang, Q.

National Institutes of Health

6/1/125/31/14

Project: Research projectExploratory/Developmental Grants

alpha-Synuclein
Parkinson Disease
Synucleins
Drug Design
Intrinsically Disordered Proteins

Publications 2003 2019

  • 1073 Citations
  • 13 h-Index
  • 20 Article
  • 1 Chapter
  • 1 Comment/debate

Constructing kinetically controlled denaturation isotherms of folded proteins using denaturant-pulse chaperonin binding

O’Neil, P. T., Machen, A. J., Thompson, J. A., Wang, W., Hoang, Q., Baldwin, M. R., Khar, K. R., Karanicolas, J. & Fisher, M. T., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 293-304 12 p. (Methods in Molecular Biology; vol. 1873).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chaperonins
Immobilized Proteins
Protein Unfolding
Proteins
Protein Stability

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1

Tashiro, S., Caaveiro, J. M. M., Nakakido, M., Tanabe, A., Nagatoishi, S., Tamura, Y., Matsuda, N., Liu, D., Hoang, Q. & Tsumoto, K., Sep 21 2018, In : ACS chemical biology. 13, 9, p. 2783-2793 11 p.

Research output: Contribution to journalArticle

X Ray Crystallography
Oxidation-Reduction
Disease Progression
X ray crystallography
Assays

Sulfonamido-2-arylbenzoxazole GroEL/ES inhibitors are potent antibacterials against methicillin-resistant Staphylococcus aureus (MRSA)

Abdeen, S., Kunkle, T., Salim, N., Ray, A. M., Mammadova, N., Summers, C., Stevens, M., Ambrose, A., Park, Y., Schultz, P. G., Horwich, A. L., Hoang, Q., Chapman, E. & Johnson, S., Jan 1 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Acinetobacter baumannii
Enterococcus faecium
Klebsiella pneumoniae
Methicillin-Resistant Staphylococcus aureus
Pseudomonas aeruginosa

Combating Parkinson's disease-associated toxicity by modulating proteostasis

Park, Y. & Hoang, Q., Jan 31 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 803-804 2 p.

Research output: Contribution to journalComment/debate

32 Citations

Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein

Wang, W., Nguyen, L. T. T., Burlak, C., Chegini, F., Guo, F., Chataway, T., Ju, S., Fisher, O. S., Miller, D. W., Datta, D., Wu, F., Wu, C. X., Landeru, A., Wells, J. A., Cookson, M. R., Boxer, M. B., Thomas, C. J., Gai, W. P., Ringe, D., Petsko, G. A. & 1 othersHoang, Q., Aug 23 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. 9587-9592 6 p.

Research output: Contribution to journalArticle

Caspase 1
alpha-Synuclein
Parkinson Disease
Inflammasomes
Lewy Bodies