Quyen Hoang

  • 1175 Citations
  • 13 h-Index
20032020
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  • 1 Similar Profiles
Parkinson Disease Medicine & Life Sciences
Synucleins Medicine & Life Sciences
Chaperonins Medicine & Life Sciences
Leucine Medicine & Life Sciences
Acyl-Butyrolactones Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
Mutation Medicine & Life Sciences
Proteins Medicine & Life Sciences

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NIH Grants 2012 2020

Leucine
Phosphotransferases
Parkinson Disease
GTP Phosphohydrolases
Mutation
GTP Phosphohydrolases
Mutation
Parkinson Disease
Phosphotransferases
Parkinson Disease Associated Proteins
alpha-Synuclein
Parkinson Disease
Synucleins
Drug Design
Intrinsically Disordered Proteins

Publications 2003 2019

  • 1175 Citations
  • 13 h-Index
  • 25 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article

Constructing kinetically controlled denaturation isotherms of folded proteins using denaturant-pulse chaperonin binding

O’Neil, P. T., Machen, A. J., Thompson, J. A., Wang, W., Hoang, Q., Baldwin, M. R., Khar, K. R., Karanicolas, J. & Fisher, M. T., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 293-304 12 p. (Methods in Molecular Biology; vol. 1873).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chaperonins
Immobilized Proteins
Protein Unfolding
Proteins
Protein Stability

Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB)inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections

Washburn, A., Abdeen, S., Ovechkina, Y., Ray, A. M., Stevens, M., Chitre, S., Sivinski, J., Park, Y., Johnson, J., Hoang, Q., Chapman, E., Parish, T. & Johnson, S., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Polypharmacology
Chaperonins
Mycobacterium Infections
Protein Tyrosine Phosphatases
Mycobacterium tuberculosis
1 Citation (Scopus)

HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules

Stevens, M., Abdeen, S., Salim, N., Ray, A. M., Washburn, A., Chitre, S., Sivinski, J., Park, Y., Hoang, Q., Chapman, E. & Johnson, S., May 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 9, p. 1106-1112 7 p.

Research output: Contribution to journalArticle

Open Access
Chaperonin 10
Chaperonins
Biological Products
Molecules
Pharmaceutical Preparations

Parkinson’s disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics

Wu, C. X., Liao, J., Park, Y., Reed, X., Engel, V. A., Hoang, N. C., Takagi, Y., Johnson, S., Wang, M., Federici, M., Jeremy Nichols, R., Sanishvili, R., Cookson, M. R. & Hoang, Q., Jan 1 2019, In : Journal of Biological Chemistry. 294, 15, p. 5907-5913 7 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
ras Proteins
Leucine
Parkinson Disease
Conformations
1 Citation (Scopus)

The Parkinson's disease-associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2

Huang, X., Wu, C., Park, Y., Long, X., Hoang, Q. & Liao, J., Apr 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 4, p. 4814-4823 10 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Leucine
Parkinson Disease
Phosphotransferases
Conformations