Raj Vuppalanchi

  • 4597 Citations
  • 34 h-Index
20052020

Research output per year

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Publications

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2020

A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis

AESOP Study Investigators, Jul 2020, In : Journal of Hepatology. 73, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD

Gawrieh, S., Sethunath, D., Cummings, O. W., Kleiner, D. E., Vuppalanchi, R., Chalasani, N. & Tuceryan, M., Aug 2020, In : Annals of Diagnostic Pathology. 47, 151518.

Research output: Contribution to journalArticle

Cannabidiol (CBD) Consumption and Perceived Impact on Extrahepatic Symptoms in Patients with Autoimmune Hepatitis

Mathur, K., Vuppalanchi, V., Gelow, K., Vuppalanchi, R. & Lammert, C., Jan 1 2020, In : Digestive diseases and sciences. 65, 1, p. 322-328 7 p.

Research output: Contribution to journalArticle

Open Access

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension

The Belapectin (GR-MD-02) Study Investigators, Apr 2020, In : Gastroenterology. 158, 5, p. 1334-1345.e5

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid

Eaton, J. E., Vuppalanchi, R., Reddy, R., Sathapathy, S., Ali, B. & Kamath, P. S., Apr 1 2020, In : Hepatology. 71, 4, p. 1511-1514 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
1 Scopus citations

Quantitative Prediction of CYP3A4- and CYP3A5-Mediated Drug Interactions

Guo, Y., Lucksiri, A., Dickinson, G. L., Vuppalanchi, R. K., Hilligoss, J. K. & Hall, S. D., Jan 1 2020, In : Clinical Pharmacology and Therapeutics. 107, 1, p. 246-256 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Selonsertib for patients with bridging fibrosis or compensated cirrhosis due to NASH: Results from randomized phase III STELLAR trials

STELLAR-3 and STELLAR-4 Investigators, Jul 2020, In : Journal of Hepatology. 73, 1, p. 26-39 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Significant Medical Comorbidities Are Associated With Lower Causality Scores in Patients Presenting With Suspected Drug-Induced Liver Injury

Ghabril, M., Gu, J., Yoder, L., Corbito, L., Dakhoul, L., Ringel, A., Beyer, C. D., Vuppalanchi, R., Barnhart, H., Hayashi, P. H. & Chalasani, N., Apr 1 2020, In : Clinical and translational gastroenterology. 11, 4, p. e00141

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2019

Development and Validation of a Model Consisting of Comorbidity Burden to Calculate Risk of Death Within 6 Months for Patients With Suspected Drug-Induced Liver Injury

Ghabril, M., Gu, J., Yoder, L., Corbito, L., Ringel, A., Beyer, C. D., Vuppalanchi, R., Barnhart, H., Hayashi, P. H. & Chalasani, N., Nov 2019, In : Gastroenterology. 157, 5, p. 1245-1252.e3

Research output: Contribution to journalArticle

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

NASH Clinical Research Network, Aug 2019, In : Clinical Gastroenterology and Hepatology. 17, 9, p. 1877-1885.e5

Research output: Contribution to journalArticle

17 Scopus citations

Fecal microbiota transplantation for the treatment of recurrent and severe Clostridium difficile infection in solid organ transplant recipients: A multicenter experience

Cheng, Y. W., Phelps, E., Ganapini, V., Khan, N., Ouyang, F., Xu, H., Khanna, S., Tariq, R., Friedman-Moraco, R. J., Woodworth, M. H., Dhere, T., Kraft, C. S., Kao, D., Smith, J., Le, L., El-Nachef, N., Kaur, N., Kowsika, S., Ehrlich, A., Smith, M. & 8 others, Safdar, N., Misch, E. A., Allegretti, J. R., Flynn, A., Kassam, Z., Sharfuddin, A., Vuppalanchi, R. & Fischer, M., Feb 1 2019, In : American Journal of Transplantation. 19, 2, p. 501-511 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis

for the NASH CRN, Jan 1 2019, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Is Fasting Necessary for Individuals with Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?

Vuppalanchi, R., Weber, R., Russell, S., Gawrieh, S., Samala, N., Slaven, J. E., Harden, L. & Chalasani, N., Jun 1 2019, In : American Journal of Gastroenterology. 114, 6, p. 995-997 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
7 Scopus citations

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

REGENERATE Study Investigators, Dec 14 2019, In : The Lancet. 394, 10215, p. 2184-2196 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Older Age and Disease Duration Are Highly Associated with Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis

Dakhoul, L., Jones, K. R., Gawrieh, S., Ghabril, M., McShane, C., Vuppalanchi, R., Vilar-Gomez, E., Nephew, L., Chalasani, N. & Lammert, C., Jun 15 2019, In : Digestive diseases and sciences. 64, 6, p. 1705-1710 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase 3/7 activation in subjects with non-alcoholic fatty liver disease

Shiffman, M., Freilich, B., Vuppalanchi, R., Watt, K., Chan, J. L., Spada, A., Hagerty, D. T. & Schiff, E., Jan 2019, In : Alimentary Pharmacology and Therapeutics. 49, 1, p. 64-73 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Randomized Controlled Trial of a Leucine-Metformin-Sildenafil Combination (NS-0200) on Weight and Metabolic Parameters

Zemel, M. B., Kolterman, O., Rinella, M., Vuppalanchi, R., Flores, O., Barritt, A. S., Siddiqui, M. & Chalasani, N., Jan 1 2019, In : Obesity. 27, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial

the NASH Clinical Research Network, May 2019, In : Alimentary Pharmacology and Therapeutics. 49, 9, p. 1205-1213 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Vibration-Controlled Transient Elastography to Assess Fibrosis and Steatosis in Patients With Nonalcoholic Fatty Liver Disease

NASH Clinical Research Network, Jan 2019, In : Clinical Gastroenterology and Hepatology. 17, 1, p. 156-163.e2

Research output: Contribution to journalArticle

45 Scopus citations
2018

Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis

for the NASH CRN, Mar 2018, In : Alimentary Pharmacology and Therapeutics. 47, 5, p. 645-656 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Liver Stiffness Measurements in Patients with Noncirrhotic Portal Hypertension—The Devil Is in the Details

Vuppalanchi, R., Mathur, K., Pyko, M., Samala, N. & Chalasani, N., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

9 Scopus citations

Performance characteristics of vibration-controlled transient elastography for evaluation of nonalcoholic fatty liver disease

for the NASH Clinical Research Network, Jan 2018, In : Hepatology. 67, 1, p. 134-144 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

Randomised clinical trial: a leucine-metformin-sildenafil combination (NS-0200) vs placebo in patients with non-alcoholic fatty liver disease

Chalasani, N., Vuppalanchi, R., Rinella, M., Middleton, M. S., Siddiqui, M. S., Barritt, A. S., Kolterman, O., Flores, O., Alonso, C., Iruarrizaga-Lejarreta, M., Gil-Redondo, R., Sirlin, C. B. & Zemel, M. B., Jun 2018, In : Alimentary Pharmacology and Therapeutics. 47, 12, p. 1639-1651 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Aug 1 2017, In : Journal of Pediatrics. 187, p. 141-146.e1

Research output: Contribution to journalArticle

26 Scopus citations
17 Scopus citations

Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis

Yang, J. D., Abdelmalek, M. F., Guy, C. D., Gill, R. M., Lavine, J. E., Yates, K., Klair, J., Terrault, N. A., Clark, J. M., Unalp-Arida, A., Diehl, A. M., Suzuki, A., Dasarathy, S., Dasarathy, J., Hawkins, C., McCullough, A. J., Pagadala, M., Pai, R., Sargent, R., Bashir, M. & 80 others, Buie, S., Kigongo, C., Pan, Y. P., Piercy, D., Chalasani, N., Cummings, O. W., Gawrieh, S., Ghabril, M., Marri, S., Ragozzino, L., Sandrasegaran, K., Vuppalanchi, R., King, D., Osmack, P., Siegner, J., Stewart, S., Neuschwander-Tetri, B. A., Torretta, S., Ang, B., Behling, C., Bhatt, A., Loomba, R., Middleton, M., Patton, H., Sirlin, C., Aouizerat, B., Bass, N. M., Brandman, D., Ferrell, L. D., Hameed, B., Ramos, C., Ungermann, A., Atla, P., Croft, B., Garcia, R., Garcia, S., Sheikh, M., Singh, M., Boyett, S., Carucci, L., Contos, M. J., Kraft, K., Luketic, V. A. C., Puri, P., Sanyal, A. J., Schlosser, J., Siddiqui, M. S., Wolford, B., Ackermann, S., Cooney, S., Coy, D., Gelinas, K., Kowdley, K. V., Lee, M., Pierce, T., Mooney, J., Nelson, J. E., Shaw, C., Siddique, A., Wang, C., Brunt, E. M., Fowler, K., Kleiner, D. E., Grave, G. D., Doo, E. C., Hoofnagle, J. H., Robuck, P. R., Sherker, A., Belt, P., Donithan, M., Hallinan, E., Isaacson, M., May, K. P., Miriel, L., Sternberg, A., Tonascia, J., Ünalp-Arida, A., Van Natta, M., Vaughn, I. & Wilson, L., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 127-131.e2

Research output: Contribution to journalArticle

17 Scopus citations
2 Scopus citations
2016

A not-so-sweet diagnosis: Secondary biliary cirrhosis from a "lollipop" stone

Gromski, M. A., Vuppalanchi, R., Sherman, S. & Fogel, E., 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

1 Scopus citations

Febuxostat-induced acute liver injury

Bohm, M., Vuppalanchi, R., Chalasani, N., Fontana, R. J., Watkins, P. B., Bonkovsky, H. L., Davern, T., Serrano, J. & Rochon, J., Mar 1 2016, In : Hepatology. 63, 3, p. 1047-1049 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms

the NASH Clinical Research Network, Dec 1 2016, In : Alimentary Pharmacology and Therapeutics. 44, 11-12, p. 1253-1264 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Nodular regenerative hyperplasia after treatment with trastuzumab emtansine

Force, J., Saxena, R., Schneider, B., Storniolo, A. M., Sledge, G. W., Chalasani, N. & Vuppalanchi, R., Jan 20 2016, In : Journal of Clinical Oncology. 34, 3, p. e9-e12

Research output: Contribution to journalArticle

14 Scopus citations

Risk of Liver Injury Associated with Green Tea Extract in SLIMQUICK® Weight Loss Products: Results from the DILIN Prospective Study

Zheng, E. X., Rossi, S., Fontana, R. J., Vuppalanchi, R., Hoofnagle, J. H., Khan, I. & Navarro, V. J., Aug 1 2016, In : Drug Safety. 39, 8, p. 749-754 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
1 Scopus citations

Secondary Sclerosing Cholangitis From Spontaneous Choledochoduodenal Fistula

Gromski, M. A., Fogel, E. & Vuppalanchi, R., 2016, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Clinical and histologic features of azithromycin-induced liver injury

Martinez, M. A., Vuppalanchi, R., Fontana, R. J., Stolz, A., Kleiner, D. E., Hayashi, P. H., Gu, J., Hoofnagle, J. H. & Chalasani, N., Jan 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 2, p. 369-376.e3

Research output: Contribution to journalArticle

33 Scopus citations

Drug-induced liver injury

Fisher, K., Vuppalanchi, R. & Saxena, R., Jul 1 2015, In : Archives of Pathology and Laboratory Medicine. 139, 7, p. 876-887 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

Endoscopic Sedation in Roux-en-Y Gastric Bypass

Vuppalanchi, R., 2015, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

93 Scopus citations

Features and outcomes of 899 patients with drug-induced liver injury: The DILIN prospective study

Chalasani, N., Bonkovsky, H. L., Fontana, R., Lee, W., Stolz, A., Talwalkar, J., Reddy, K. R., Watkins, P. B., Navarro, V., Barnhart, H., Gu, J., Serrano, J., Ahmad, J., Bach, N., Bansal, M., Barnhart, H. X., Beavers, K., Calvo, F. O., Chang, C., Conjeevaram, H. & 56 others, Conner, G., Darling, J., De Boer, Y., Dieterich, D., Dipaola, F., Durazo, F. A., Everhart, J. E., Fontana, R. J., Ghabril, M. S., Goldstein, D., Gopalreddy, V., Grewal, P., Hayashi, P. H., Hoofnagle, J., Kaplowitz, N., Liangpunsakul, S., Lichtman, S., Liu, L., Navarro, V. J., Odin, J., Rossi, S., Russo, M., Schiano, T., Sherker, A. H., Vuppalanchi, R., Zacks, S., Balasco, A., Chesney, K., Corne, A., Cummings, S., Groseclose, G., Hammett, A., Hooker, J., Kesar, V., Mao, S., Marks, K., McFadden, R., Melgoza, Y., Mikhail, S., Milstein, S., Morlan, W., Peacock, V., Rosado, N., Russell, T., Vega, M., Verma, M., Walker, P., Yalamanchili, R., McClanahan-Crowder, M., Galan, K., Chau, T., Ragavan, K., Rostami, H., Puglisi-Scharenbroich, C., Torrance, R. J. & Van Raaphorst, R., Jun 1 2015, In : Gastroenterology. 148, 7, p. 1340-1352.e7

Research output: Contribution to journalArticle

265 Scopus citations

Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease

Corey, K. E., Vuppalanchi, R., Vos, M., Kohli, R., Molleston, J. P., Wilson, L., Unalp-Arida, A., Cummings, O. W., Lavine, J. E. & Chalasani, N., Mar 7 2015, In : Journal of pediatric gastroenterology and nutrition. 60, 3, p. 360-367 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
9 Scopus citations
21 Scopus citations

Serum metabolic signatures of primary biliary cirrhosis and primary sclerosing cholangitis

Bell, L. N., Wulff, J., Comerford, M., Vuppalanchi, R. & Chalasani, N., Jan 1 2015, In : Liver International. 35, 1, p. 263-274 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Severe Drug-Induced Skin and Liver Injury from Rivaroxaban

Barrett, P., Vuppalanchi, R., Masuoka, H. & Chalasani, N., Jun 5 2015, In : Digestive diseases and sciences. 60, 6, p. 1856-1858 3 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Drug-induced nodular regenerative hyperplasia

Ghabril, M. & Vuppalanchi, R., May 2014, In : Seminars in Liver Disease. 34, 2, p. 240-245 6 p.

Research output: Contribution to journalArticle

20 Scopus citations