Rebecca Chan

  • 2741 Citations
  • 27 h-Index
1992 …2018

Research output per year

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Publications

2008

Requirement for p85α regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KIT

Munugalavadla, V., Sims, E. C., Chan, R. J., Lenz, S. D. & Kapur, R., Mar 1 2008, In : Experimental Hematology. 36, 3, p. 301-308 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
26 Scopus citations
2007
29 Scopus citations

MOZ and MOZ-CBP cooperate with NF-κB to activate transcription from NF-κB-dependent promoters

Chan, E. M., Chan, R. J., Comer, E. M., Goulet, R. J., Crean, C. D., Brown, Z. D., Fruehwald, A. M., Yang, Z., Boswell, H. S., Nakshatri, H. & Gabig, T. G., Dec 1 2007, In : Experimental Hematology. 35, 12, p. 1782-1792 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase

Chan, R. J. & Feng, G. S., Feb 1 2007, In : Blood. 109, 3, p. 862-867 6 p.

Research output: Contribution to journalReview article

195 Scopus citations
2006

Reduction of Shp-2 expression by small interfering RNA reduces murine embryonic stem cell-derived in vitro hematopoietic differentiation

Zou, G. M., Chan, R. J., Shelley, W. C. & Yoder, M. C., Mar 1 2006, In : STEM CELLS. 24, 3, p. 587-594 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Shp-2 heterozygous hematopoietic stem cells have deficient repopulating ability due to diminished self-renewal

Chan, R. J., Li, Y., Hass, M. N., Walter, A., Voorhorst, C. S., Shelley, W. C., Yang, Z., Orschell, C. M. & Yoder, M. C., Sep 2006, In : Experimental Hematology. 34, 9, p. 1229-1238 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

The role of Hex in hemangioblast and hematopoietic development.

Chan, R. J., Hromas, R. & Yoder, M. C., 2006, In : Methods in molecular biology (Clifton, N.J.). 330, p. 123-133 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2005

12-O-Tetradecanoylphorbol-13-acetate in acute myeloid leukemia

Chan, R. J. & Cripe, L. D., Oct 1 2005, In : Leukemia Research. 29, 10, p. 1107-1108 2 p.

Research output: Contribution to journalEditorial

2 Scopus citations

AML1-FOG2 fusion protein in myelodysplasia

Chan, E. M., Comer, E. M., Brown, F. C., Richkind, K. E., Holmes, M. L., Chong, B. H., Shiffman, R., Zhang, D. E., Slovak, M. L., Willman, C. L., Noguchi, C. T., Li, Y., Heiber, D. J., Kwan, L., Chan, R. J., Vance, G. H., Ramsey, H. C. & Hromas, R. A., Jun 1 2005, In : Blood. 105, 11, p. 4523-4526 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

Chan, R. J., Leedy, M. B., Munugalavadla, V., Voorhorst, C. S., Li, Y., Yu, M. & Kapur, R., May 1 2005, In : Blood. 105, 9, p. 3737-3742 6 p.

Research output: Contribution to journalArticle

121 Scopus citations

Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4

Li, Y., McClintick, J., Zhong, L., Edenberg, H. J., Yoder, M. C. & Chan, R. J., Jan 15 2005, In : Blood. 105, 2, p. 635-637 3 p.

Research output: Contribution to journalArticle

207 Scopus citations
2004

Identification of trans-acting factors by electrophoretic mobility shift assay.

Chan, R. J., You, M. & Feng, G. S., 2004, In : Methods in molecular biology (Clifton, N.J.). 249, p. 7-20 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells

Zhong, L., Li, W., Yang, Z., Qing, K., Tan, M., Hansen, J., Li, Y., Chen, L., Chan, R. J., Bischof, D., Maina, N., Weigel-Kelley, K. A., Zhao, W., Larsen, S. H., Yoder, M. C., Shou, W. & Srivastava, A., Dec 2004, In : Human gene therapy. 15, 12, p. 1207-1218 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to Improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo

Zhong, L., Chen, L., Li, Y., Qing, K., Weigel-Kelley, K. A., Chan, R. J., Yoder, M. C. & Srivastava, A., Nov 1 2004, In : Molecular Therapy. 10, 5, p. 950-957 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

The multiple facets of hematopoietic stem cells.

Chan, R. J. & Yoder, M. C., Jul 2004, In : Current neurovascular research. 1, 3, p. 197-206 10 p.

Research output: Contribution to journalReview article

20 Scopus citations
2003

A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis

Chan, R. J., Johnson, S. A., Li, Y., Yoder, M. C. & Feng, G. S., Sep 15 2003, In : Blood. 102, 6, p. 2074-2080 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

The homeoprotein Hex is required for hemangioblast differentiation

Guo, Y., Chan, R., Ramsey, H., Li, W., Xie, X., Shelley, W. C., Martinez-Barbera, J. P., Bort, B., Zaret, K., Yoder, M. & Hromas, R., Oct 1 2003, In : Blood. 102, 7, p. 2428-2435 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs

Xie, X., Chan, R. J., Johnson, S. A., Starr, M., McCarthy, J., Kapur, R. & Yoder, M. C., Feb 15 2003, In : Blood. 101, 4, p. 1329-1335 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
2002

On physician-assisted suicide.

Chan, R. J., Jan 1 2002, In : The Pharos of Alpha Omega Alpha-Honor Medical Society. Alpha Omega Alpha. 65, 2, p. 49-50 2 p.

Research output: Contribution to journalComment/debate

10 Scopus citations
2001

Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis

Palis, J., Chan, R. J., Koniski, A., Patel, R., Starr, M. & Yoder, M. C., Apr 10 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 8, p. 4528-4533 6 p.

Research output: Contribution to journalArticle

127 Scopus citations
2000

Mammalian 3-hydroxyisobutyrate dehydrogenase

Hawes, J. W., Crabb, D. W., Chan, R. J., Rougraff, P. M., Paxton, R. & Harris, R. A., Jan 1 2000, In : Methods in Enzymology. 324, p. 218-228 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
1999

Positron emission tomography scans in the evaluation of postchemotherapy residual masses in patients with seminoma

Ganjoo, K. N., Chan, R. J., Sharma, M. & Einhorn, L. H., Nov 1999, In : Journal of Clinical Oncology. 17, 11, p. 3457-3460 4 p.

Research output: Contribution to journalArticle

84 Scopus citations
1997

A direct repeat (DR-1) element in the first exon modulates transcription of the preproenkephalin A gene

Chan, R. M., Stewart, M. J. & Crabb, D. W., Apr 1 1997, In : Molecular Brain Research. 45, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
1996
1 Scopus citations
1995

Chemical Modification and Site-Directed Mutagenesis Studies of Rat 3-Hydroxyisobutyrate Dehydrogenase

Hawes, J. W., Crabb, D. W., Chan, R. M., Harris, R. A. & Rougraff, P. M., Sep 1 1995, In : Biochemistry. 34, 13, p. 4231-4237 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
1994
13 Scopus citations
3 Scopus citations