Reuben Kapur

  • 4275 Citations
  • 35 h-Index
1991 …2019
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Publications 1991 2019

  • 4275 Citations
  • 35 h-Index
  • 125 Article
  • 3 Review article
  • 2 Letter
  • 1 Editorial
Article

Analysis of an evolutionarily-conserved function-associated molecule (FAM) on murine natural killer (NK) cells

Acevedo, A., Kapur, R. & Harris, D. T., 1991, In : Developmental and Comparative Immunology. 15, SUPPL. 1

Research output: Contribution to journalArticle

Natural Killer Cells
Natural Killer Cells
Antigens
Monoclonal Antibodies
Histocompatibility Antigens Class I
Lymphokine-Activated Killer Cells
57 Citations (Scopus)
Proto-Oncogene Proteins c-kit
Erythropoietin Receptors
Stem Cell Factor
Erythropoietin
Cells
3 Citations (Scopus)

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

Prudent, R., Demoncheaux, N., Diemer, H., Collin-Faure, V., Kapur, R., Paublant, F., Lafanechère, L., Cianférani, S. & Rabilloud, T., Dec 1 2018, In : PLoS One. 13, 12, e0208979.

Research output: Contribution to journalArticle

Lim Kinases
Actin Depolymerizing Factors
Phosphorylation
Myeloid Cells
Proteomics
3 Citations (Scopus)

A rare complex DNA rearrangement in the murine Steel gene results in exon duplication and a lethal phenotype

Chandra, S., Kapur, R., Chuzhanova, N., Summey, V., Prentice, D., Barker, J., Cooper, D. N. & Williams, D. A., Nov 15 2003, In : Blood. 102, 10, p. 3548-3555 8 p.

Research output: Contribution to journalArticle

Gene Rearrangement
Steel
Exons
Genes
Phenotype
18 Citations (Scopus)

A species-conserved NK cell antigen receptor is a novel vimentin-like molecule

Harris, D. T., Kapur, R., Frye, C., Acevedo, A., Camenisch, T., Jaso-Friedmann, L. & Evans, D. L., 1992, In : Developmental and Comparative Immunology. 16, 5, p. 395-403 9 p.

Research output: Contribution to journalArticle

Natural Killer Cell Receptors
Antigen Receptors
Vimentin
Natural Killer Cells
Signal Transduction
14 Citations (Scopus)

Balanced interactions between Lyn, the p85α Regulatory Subunit of Class I A phosphatidylinositol-3-kinase, and SHIP Are essential for mast cell growth and maturation

Ma, P., Vemula, S., Munugalavadla, V., Chen, J., Sims, E., Borneo, J., Kondo, T., Ramdas, B., Mali, R. S., Li, S., Hashino, E., Takemoto, C. & Kapur, R., Oct 2011, In : Molecular and Cellular Biology. 31, 19, p. 4052-4062 11 p.

Research output: Contribution to journalArticle

Class I Phosphatidylinositol 3-Kinases
Mast Cells
Bone Marrow
Phosphatidylinositol 3-Kinase
Growth
5 Citations (Scopus)

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

Garg, G., Muschaweckh, A., Moreno, H., Vasanthakumar, A., Floess, S., Lepennetier, G., Oellinger, R., Zhan, Y., Regen, T., Hiltensperger, M., Peter, C., Aly, L., Knier, B., Palam, L. R., Kapur, R., Kaplan, M., Waisman, A., Rad, R., Schotta, G., Huehn, J. & 2 others, Kallies, A. & Korn, T., Feb 12 2019, In : Cell Reports. 26, 7, p. 1854-1868.e5

Research output: Contribution to journalArticle

Methylation
T-cells
Methyltransferases
Regulatory T-Lymphocytes
Interleukin-6
9 Citations (Scopus)

Bmi1 promotes erythroid development through regulating ribosome biogenesis

Gao, R., Chen, S., Kobayashi, M., Yu, H., Zhang, Y., Wan, Y., Young, S. K., Soltis, A., Yu, M., Vemula, S., Fraenkel, E., Cantor, A., Antipin, Y., Xu, Y., Yoder, M., Wek, R., Ellis, S. R., Kapur, R., Zhu, X. & Liu, Y., Mar 1 2015, In : Stem Cells. 33, 3, p. 925-938 14 p.

Research output: Contribution to journalArticle

Diamond-Blackfan Anemia
Ribosomes
Erythroid Precursor Cells
Ribosomal Proteins
Hematopoietic Stem Cells
50 Citations (Scopus)

c-Kit-Mediated Overlapping and Unique Functional and Biochemical Outcomes via Diverse Signaling Pathways

Hong, L., Munugalavadla, V. & Kapur, R., Feb 2004, In : Molecular and Cellular Biology. 24, 3, p. 1401-1410 10 p.

Research output: Contribution to journalArticle

Binding Sites
Phosphatidylinositol 3-Kinase
Proto-Oncogene Proteins c-kit
MAP Kinase Kinase 4
src-Family Kinases
6 Citations (Scopus)

Class i A pi3kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes

Krishnan, S., Mali, R. S., Koehler, K. R., Vemula, S., Chatterjee, A., Ghosh, J., Ramdas, B., Ma, P., Hashino, E. & Kapur, R., Jan 4 2012, In : PLoS One. 7, 1, e28979.

Research output: Contribution to journalArticle

Stem Cell Factor
mast cells
Mast Cells
Genes
Cells
1 Citation (Scopus)

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML

Sayar, H., Liu, Y., Gao, R., Zaid, M. A., Cripe, L., Weisenbach, J., Sargent, K. J., Nassiri, M., Li, L., Konig, H., Suvannasankha, A., Pan, F., Shanmugam, R., Goswami, C., Kapur, R., Xu, M. & Scott Boswell, H., Jan 1 2018, In : Oncotarget. 9, 5, p. 5703-5715 13 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Mutation
Epigenetic Repression
Histone Deacetylase Inhibitors
Chromatin Assembly and Disassembly
72 Citations (Scopus)
Focal Adhesion Protein-Tyrosine Kinases
Mitogen-Activated Protein Kinases
Cell Survival
Chemical activation
Cells
61 Citations (Scopus)

Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis

Li, B., Jia, N., Kapur, R. & Chun, K., Jun 1 2006, In : Blood. 107, 11, p. 4291-4299 9 p.

Research output: Contribution to journalArticle

Erythropoiesis
Cell proliferation
Ubiquitin
Cell Differentiation
Erythroblasts
10 Citations (Scopus)

Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells

Orschell, C., Borneo, J., Munugalavadla, V., Ma, P., Sims, E., Ramdas, B., Yoder, M. & Kapur, R., May 2008, In : Experimental Hematology. 36, 5, p. 655-666 12 p.

Research output: Contribution to journalArticle

src-Family Kinases
Hematopoietic Stem Cells
Bone Marrow Cells
Stem Cells
Phosphotransferases
446 Citations (Scopus)

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

Roberts, A. W., Chaekyun, K., Zhen, L., Lowe, J. B., Kapur, R., Petryniak, B., Spaetti, A., Pollock, J. D., Borneo, J. B., Bradford, G. B., Atkinson, S. J., Dinauer, M. C. & Williams, D. A., Feb 1999, In : Immunity. 10, 2, p. 183-196 14 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Neutrophils
Exudates and Transudates
rac GTP-Binding Proteins
L-Selectin
76 Citations (Scopus)

Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

Shi, J., Wu, X., Surma, M., Vemula, S., Zhang, L., Yang, Y., Kapur, R. & Wei, L., Feb 2013, In : Cell Death and Disease. 4, 2

Research output: Contribution to journalArticle

Actin Cytoskeleton
Actin Depolymerizing Factors
Actomyosin
Stress Fibers
Phosphorylation
16 Citations (Scopus)

Distinct roles of stress-activated protein kinases in fanconi anemia type C deficient hematopoiesis

Saadatzadeh, M. R., Bijangi-Vishehsaraei, K., Kapur, R. & Haneline, L., Mar 19 2009, In : Blood. 113, 12, p. 2655-2660 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
JNK Mitogen-Activated Protein Kinases
Hematopoiesis
Heat-Shock Proteins
Protein Kinases
5 Citations (Scopus)

DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms

O'Leary, H. A., Capitano, M., Cooper, S., Mantel, C., Boswell, H., Kapur, R., Ramdas, B., Chan, R., Deng, L., Qu, C. K. & Broxmeyer, H., Nov 1 2017, In : Leukemia. 31, 11, p. 2468-2478 11 p.

Research output: Contribution to journalArticle

Colony-Stimulating Factors
Interleukin-3
Hematopoiesis
Granulocytes
Experimental Leukemias
31 Citations (Scopus)

Enhanced TNF-α-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1

Bijangi-Vishehsaraei, K., Saadatzadeh, M. R., Werne, A., McKenzie, K. A. W., Kapur, R., Ichijo, H. & Haneline, L., Dec 15 2005, In : Blood. 106, 13, p. 4124-4130 7 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase Kinase 5
Fanconi Anemia
Fibroblasts
Tumor Necrosis Factor-alpha
Apoptosis
109 Citations (Scopus)

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

Mantel, C. R., O'Leary, H. A., Chitteti, B. R., Huang, X., Cooper, S., Hangoc, G., Broustovetski, N., Srour, E., Lee, M. R., Messina-Graham, S., Haas, D., Falah, N., Kapur, R., Pelus, L., Bardeesy, N., Fitamant, J., Ivan, M., Kim, K. S. & Broxmeyer, H., Jun 18 2015, In : Cell. 161, 7, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Stem cells
Shock
Oxygen
3 Citations (Scopus)

Erratum: Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of rho-associated kinase via the Cxcl12/Cxcr4 signaling axis (Journal of Biological Chemistry)

Onishi, C., Mori-Kimachi, S., Hirade, T., Abe, M., Taketani, T., Suzumiya, J., Sugimoto, T., Yamaguchi, S., Kapur, R. & Fukuda, S., Nov 20 2015, In : Journal of Biological Chemistry. 290, 47, p. 28356 1 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Genes
Proteins

Erratum: Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1 (Human Molecular Genetics (2008) vol. 17(7) (936-948) 10.1093/hmg/ddm366)

Yan, J., Chen, S., Zhang, Y., Li, X., Li, Y., Wu, X., Yuan, J., Robling, A., Kapur, R., Chan, R. & Yang, F. C., Jun 15 2008, In : Human Molecular Genetics. 17, 12, p. 1876 1 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Medical Genetics
Osteoclasts
Molecular Biology
26 Citations (Scopus)

Essential role for focal adhesion kinase in regulating stress hematopoiesis

Vemula, S., Ramdas, B., Hanneman, P., Martin, J., Beggs, H. E. & Kapur, R., Nov 18 2010, In : Blood. 116, 20, p. 4103-4115 13 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Hematopoiesis
Myeloid Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Bone
4 Citations (Scopus)

Evolutionary Conservation of a Human Function‐Associated Molecule on Murine Natural Killer Cells: Expression and Function

Kapur, R., EVANS, D. L. & HARRIS, D. T., Jan 1 1994, In : Scandinavian Journal of Immunology. 40, 1, p. 50-56 7 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Monoclonal Antibodies
Wool
Lymphokines
Nylons
25 Citations (Scopus)
Erythropoietin Receptors
src-Family Kinases
Chemical activation
Phosphatidylinositol 3-Kinase
Stem Cell Factor
37 Citations (Scopus)

Functional B-1 progenitor cells are present in the hematopoietic stem cell-deficient embryo and depend on Cbfβ for their development

Kobayashi, M., Shelley, W. C., Seo, W., Vemula, S., Lin, Y., Liu, Y., Kapur, R., Taniuchi, I. & Yoshimoto, M., Aug 19 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 33, p. 12151-12156 6 p.

Research output: Contribution to journalArticle

Core Binding Factor beta Subunit
B-Lymphoid Precursor Cells
Hematopoietic Stem Cells
Embryonic Structures
Liver
27 Citations (Scopus)

Functional p85α gene is required for normal murine fetal erythropoiesis

Huddleston, H., Tan, B., Yang, F. C., White, H., Wenning, M. J., Orazi, A., Yoder, M., Kapur, R. & Ingram, D., Jul 1 2003, In : Blood. 102, 1, p. 142-145 4 p.

Research output: Contribution to journalArticle

Erythroid Precursor Cells
Erythropoiesis
Phosphotransferases
Genes
Liver
1 Citation (Scopus)
Lymphoid Progenitor Cells
Methyltransferases
Retroviridae
Hematopoietic Stem Cells
Stem cells
47 Citations (Scopus)

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans

Lasater, E. A., Li, F., Bessler, W. K., Estes, M. L., Vemula, S., Hingtgen, C. M., Dinauer, M. C., Kapur, R., Conway, S. & Ingram, D., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, p. 859-870 12 p.

Research output: Contribution to journalArticle

Neurofibromin 1
Neurofibromatosis 1
Blood Vessels
Inflammation
Neointima
28 Citations (Scopus)
Systemic Mastocytosis
GTP Phosphohydrolases
Acute Myeloid Leukemia
Phosphotransferases
Hematopoietic Stem Cells
60 Citations (Scopus)

Genetic evidence for convergence of c-Kit- and α4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells

Tan, B. L., Yazicioglu, M. N., Ingram, D., McCarthy, J., Borneo, J., Williams, D. A. & Kapur, R., Jun 15 2003, In : Blood. 101, 12, p. 4725-4732 8 p.

Research output: Contribution to journalArticle

Stem Cell Factor
1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Mast Cells
Integrins
7 Citations (Scopus)

Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms

Hu, P., Carlesso, N., Xu, M., Liu, Y., Nebreda, A. R., Takemoto, C. & Kapur, R., Jun 8 2012, In : Journal of Biological Chemistry. 287, 24, p. 20258-20269 12 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Chemotaxis
Mast Cells
Cell Differentiation
Microphthalmia-Associated Transcription Factor
24 Citations (Scopus)

Genetic reduction of class Ia PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo

Haneline, L., White, H., Yang, F. C., Chen, S., Orschell, C., Kapur, R. & Ingram, D., Feb 15 2006, In : Blood. 107, 4, p. 1375-1382 8 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Fetal Movement
Hematopoiesis
Hematopoietic Stem Cells
Stem cells
8 Citations (Scopus)

Global microRNA expression is essential for murine mast cell development invivo

Oh, S. Y., Brandal, S., Kapur, R., Zhu, Z. & Takemoto, C. M., Oct 1 2014, In : Experimental Hematology. 42, 10, p. 919-923 5 p.

Research output: Contribution to journalArticle

MicroRNAs
Mast Cells
Immunoglobulin E
Ribonuclease III
Connective Tissue Cells
11 Citations (Scopus)

Heterozygous inactivation of the NF1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway

Stansfield, B. K., Bessler, W. K., Mali, R., Mund, J. A., Downing, B., Li, F., Sarchet, K. N., DiStasi, M. R., Conway, S., Kapur, R. & Ingram, D., Mar 2013, In : Human Molecular Genetics. 22, 5, p. 977-988 12 p., dds502.

Research output: Contribution to journalArticle

Neurofibromatosis 1 Genes
Neointima
Neurofibromatosis 1
Myeloid Cells
Neurofibromin 1
117 Citations (Scopus)

Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

Chan, R., Leedy, M. B., Munugalavadla, V., Voorhorst, C. S., Li, Y., Yu, M. & Kapur, R., May 1 2005, In : Blood. 105, 9, p. 3737-3742 6 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Hypersensitivity
Mutation
Juvenile Myelomonocytic Leukemia
Macrophages
80 Citations (Scopus)

Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL

Wen, Q., Goldenson, B., Silver, S. J., Schenone, M., Dancik, V., Huang, Z., Wang, L. Z., Lewis, T. A., An, W. F., Li, X., Bray, M. A., Thiollier, C., Diebold, L., Gilles, L., Vokes, M. S., Moore, C. B., Bliss-Moreau, M., Verplank, L., Tolliday, N. J., Mishra, R. & 28 others, Vemula, S., Shi, J., Wei, L., Kapur, R., Lopez, C. K., Gerby, B., Ballerini, P., Pflumio, F., Gilliland, D. G., Goldberg, L., Birger, Y., Izraeli, S., Gamis, A. S., Smith, F. O., Woods, W. G., Taub, J., Scherer, C. A., Bradner, J. E., Goh, B. C., Mercher, T., Carpenter, A. E., Gould, R. J., Clemons, P. A., Carr, S. A., Root, D. E., Schreiber, S. L., Stern, A. M. & Crispino, J. D., Aug 3 2012, In : Cell. 150, 3, p. 575-589 15 p.

Research output: Contribution to journalArticle

Leukemia, Megakaryoblastic, Acute
Aurora Kinase A
Polyploidy
Megakaryocytes
Small Interfering RNA
19 Citations (Scopus)

IL-4-stimulated NF-κB activity is required for Stat6 DNA binding

Thieu, V. T., Nguyen, E. T., McCarthy, B. P., Bruns, H. A., Kapur, R., Chang, C. H. & Kaplan, M., Aug 1 2007, In : Journal of Leukocyte Biology. 82, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

Interleukin-4
DNA
B-Lymphocytes
Gene Expression
TNF Receptor-Associated Factor 3
3 Citations (Scopus)

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells

Metts, J., Bradley, H. L., Wang, Z., Shah, N. P., Kapur, R., Arbiser, J. L. & Bunting, K. D., Dec 1 2017, In : Scientific Reports. 7, 1, 4447.

Research output: Contribution to journalArticle

Imipramine
Myeloid Cells
Acute Myeloid Leukemia
STAT5 Transcription Factor
NADPH Oxidase
11 Citations (Scopus)

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis

Cai, Z., Kotzin, J. J., Ramdas, B., Chen, S., Nelanuthala, S., Palam, L. R., Pandey, R., Mali, R. S., Liu, Y., Kelley, M., Sandusky, G., Mohseni, M., Williams, A., Henao-Mejia, J. & Kapur, R., Jan 1 2018, (Accepted/In press) In : Cell Stem Cell.

Research output: Contribution to journalArticle

Hematopoiesis
Hematopoietic Stem Cells
Interleukin-6
Long Noncoding RNA
Myeloid Cells
54 Citations (Scopus)

Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis

Wu, L., Yan, C., Czader, M., Foreman, O., Blum, J., Kapur, R. & Du, H., Jan 5 2012, In : Blood. 119, 1, p. 115-126 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Myeloid Cells
Immunosuppression
Carcinogenesis
Inflammation
4 Citations (Scopus)

Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of the rho-associated kinase via the Cxcl12/Cxcr4 signaling axis

Onish, C., Mori-Kimachi, S., Hirade, T., Abe, M., Taketani, T., Suzumiya, J., Sugimoto, T., Yamaguchi, S., Kapur, R. & Fukuda, S., Nov 7 2014, In : Journal of Biological Chemistry. 289, 45, p. 31053-31065 13 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Chemotaxis
Down-Regulation
Genes
Mutation
55 Citations (Scopus)

Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells

Samayawardhena, L. A., Kapur, R. & Craig, A. W. B., May 1 2007, In : Blood. 109, 9, p. 3679-3686 8 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Chemotaxis
Mast Cells
Integrins
Phosphotransferases
1 Citation (Scopus)

Kinase inhibitors in clinical practice: An expanding world

Pandey, R. & Kapur, R., 2017, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Immune System Diseases
Phosphotransferases
8 Citations (Scopus)

KIT associated intracellular tyrosines play an essential role in EpoR co-signaling

Hong, L., Ramdas, B., Chen, J., Harris, C., Wojchowski, D. M. & Kapur, R., Aug 2008, In : Cellular Signalling. 20, 8, p. 1513-1520 8 p.

Research output: Contribution to journalArticle

Erythropoietin Receptors
Tyrosine
Binding Sites
src-Family Kinases
43 Citations (Scopus)

KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation

Lee, Y. N., Brandal, S., Noel, P., Wentzel, E., Mendell, J. T., McDevitt, M. A., Kapur, R., Carter, M., Metcalfe, D. D. & Takemoto, C. M., Mar 31 2011, In : Blood. 117, 13, p. 3629-3640 12 p.

Research output: Contribution to journalArticle

Microphthalmia-Associated Transcription Factor
Cell proliferation
MicroRNAs
Mast Cells
Cell Proliferation
19 Citations (Scopus)

K-Ras is essential for normal fetal liver erythropoiesis

Khalaf, W. F., White, H., Wenning, M. J., Orazi, A., Kapur, R. & Ingram, D., May 1 2005, In : Blood. 105, 9, p. 3538-3541 4 p.

Research output: Contribution to journalArticle

Erythroid Precursor Cells
Erythropoiesis
Liver
Protein Isoforms
Erythroid Cells
12 Citations (Scopus)

LIM kinase inhibitor Pyr1 reduces the growth and metastatic load of breast cancers

Prunier, C., Josserand, V., Vollaire, J., Beerling, E., Petropoulos, C., Destaing, O., Montemagno, C., Hurbin, A., Prudent, R., De Koning, L., Kapur, R., Cohen, P. A., Albiges-Rizo, C., Coll, J. L., Van Rheenen, J., Billaud, M. & Lafanechère, L., Jun 15 2016, In : Cancer Research. 76, 12, p. 3541-3552 12 p.

Research output: Contribution to journalArticle

Lim Kinases
Breast Neoplasms
Growth
Microtubules
Neoplasms
2 Citations (Scopus)

Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway

Palam, L. R., Mali, R. S., Ramdas, B., Srivatsan, S. N., Visconte, V., Tiu, R. V., Vanhaesebroeck, B., Roers, A., Gerbaulet, A., Xu, M., Janga, S. C., Takemoto, C. M., Paczesny, S. & Kapur, R., Feb 22 2018, In : JCI insight. 3, 4

Research output: Contribution to journalArticle

Open Access
Myeloid Cells
Phosphatidylinositol 3-Kinases
Epigenomics
Ascorbic Acid
Azacitidine