Robert Considine

  • 22396 Citations
  • 68 h-Index
1976 …2020

Research output per year

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Publications

1997

Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

Vidal-Puig, A. J., Considine, R. V., Jimenez-Liñan, M., Werman, A., Pories, W. J., Caro, J. F. & Flier, J. S., May 15 1997, In : Journal of Clinical Investigation. 99, 10, p. 2416-2422 7 p.

Research output: Contribution to journalArticle

Open Access
679 Scopus citations

Placental leptin: an important new growth factor in intrauterine and neonatal development?

Hassink, S. G., de Lancey, E., Sheslow, D. V., Smith-Kirwin, S. M., O'Connor, D. M., Considine, R. V., Opentanova, I., Dostal, K., Spear, M. L., Leef, K., Ash, M., Spitzer, A. R. & Funanage, V. L., Jul 1997, In : Pediatrics. 100, 1, p. E1

Research output: Contribution to journalArticle

250 Scopus citations

Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients

Sharma, K., Considine, R. V., Michael, B., Dunn, S. R., Weisberg, L. S., Kurnik, B. R. C., Kurnik, P. B., O'Connor, J., Sinha, M. & Caro, J. F., Jan 1 1997, In : Kidney international. 51, 6, p. 1980-1985 6 p.

Research output: Contribution to journalArticle

Open Access
222 Scopus citations

Regulation of in vivo growth hormone secretion by leptin

Carro, E., Senaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., May 8 1997, In : Endocrinology. 138, 5, p. 2203-2206 4 p.

Research output: Contribution to journalArticle

328 Scopus citations

Serum immunoreactive leptin concentrations in patients with anorexia nervosa before and after partial weight recovery

Casanueva, F. F., Dieguez, C., Popovic, V., Peino, R., Considine, R. V. & Caro, J. F., Apr 1997, In : Biochemical and Molecular Medicine. 60, 2, p. 116-120 5 p.

Research output: Contribution to journalArticle

74 Scopus citations

Serum leptin concentrations in patients with anorexia nervosa, bulimia nervosa and non-specific eating disorders correlate with the body mass index but are independent of the respective disease

Ferron, F., Considine, R. V., Peino, R., Lado, I. G., Dieguez, C. & Casanueva, F. F., 1997, In : Clinical Endocrinology. 46, 3, p. 289-293 5 p.

Research output: Contribution to journalArticle

110 Scopus citations

Synthesis of leptin in human placenta

Señarís, R., Garcia-Caballero, T., Casabiell, X., Gallego, R., Castro, R., Considine, R. V., Dieguez, C. & Casanueva, F. F., Jan 1 1997, In : Endocrinology. 138, 10, p. 4501-4504 4 p.

Research output: Contribution to journalArticle

Open Access
317 Scopus citations

Weight regulation, leptin and growth hormone

Considine, R. V., Jan 1 1997, In : Hormone Research in Paediatrics. 48, 5, p. 116-121 6 p.

Research output: Contribution to journalArticle

70 Scopus citations
1998

Acute changes in free-fatty acids (FFA) do not alter serum leptin levels

Peinò, R., Fernández Alvarez, J., Peñalva, A., Considine, R. V., Rodriguez-Segade, S., Rodriguez-Garcia, J., Cordido, F., Casanueva, F. F. & Dieguez, C., Sep 1998, In : Journal of Endocrinological Investigation. 21, 8, p. 526-530 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

A new paradigm for type 2 diabetes mellitus: Could it be a disease of the foregut?

Hickey, M. S., Pories, W. J., MacDonald, K. G., Cory, K. A., Dohm, G. L., Swanson, M. S., Israel, R. G., Barakat, H. A., Considine, R. V., Caro, J. F. & Houmard, J. A., May 1998, In : Annals of surgery. 227, 5, p. 637-644 8 p.

Research output: Contribution to journalArticle

227 Scopus citations

Are leptin levels dependent on body fat distribution in obese men and women?

Wauters, M., Mertens, I., Considine, R., De Leeuw, I. & Van Gaal, L., Sep 1998, In : Eating and weight disorders : EWD. 3, 3, p. 124-130 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Association of leptin and hunger-satiety ratings in obese women

Heini, A. F., Lara-Castro, C., Kirk, K. A., Considine, R. V., Caro, J. F. & Weinsier, R. L., Jan 1 1998, In : International Journal of Obesity. 22, 11, p. 1084-1087 4 p.

Research output: Contribution to journalArticle

Open Access
68 Scopus citations

Effect of hydrolyzed guar fiber on fasting and postprandial satiety and satiety hormones: A double-blind, placebo-controlled trial during controlled weight loss

Heini, A. F., Lara-Castro, C., Schneider, H., Kirk, K. A., Considine, R. V. & Weinsier, R. L., Jan 1 1998, In : International Journal of Obesity. 22, 9, p. 906-909 4 p.

Research output: Contribution to journalArticle

58 Scopus citations

Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children

Klein, K. O., Larmore, K. A., De Lancey, E., Brown, J. M., Considine, R. V. & Hassink, S. G., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 10, p. 3469-3475 7 p.

Research output: Contribution to journalArticle

Open Access
189 Scopus citations

Interaction between leptin and neuropeptide Y on in vivo growth hormone secretion

Carro, E., Seoane, L. M., Señaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., Sep 28 1998, In : Neuroendocrinology. 68, 3, p. 187-191 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Serum leptin levels and energy expenditure in normal weight women

Martin, L. J., Jones, P. J. H., Considine, R. V., Su, W., Boyd, N. F. & Caro, J. F., Jan 1 1998, In : Canadian Journal of Physiology and Pharmacology. 76, 2, p. 237-241 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Short- and long-term changes in serum leptin in dieting obese women: Effects of caloric restriction and weight loss

Wadden, T. A., Considine, R. V., Foster, G. D., Anderson, D. A., Sarwer, D. B. & Caro, J. S., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 1, p. 214-218 5 p.

Research output: Contribution to journalArticle

110 Scopus citations

The Ob protein (leptin) and the kidney

Sharma, K. & Considine, R. V., Jan 1 1998, In : Kidney international. 53, 6, p. 1483-1487 5 p.

Research output: Contribution to journalArticle

59 Scopus citations
1999

An overview and update of the physiology of leptin in humans

Considine, R. V., Jun 1 1999, In : Journal of Clinical Ligand Assay. 22, 2, p. 233-235 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical endocrinology of human leptin

Van Gaal, L. F., Wauters, M. A., Mertens, I. L., Considine, R. V. & De Leeuw, I. H., Feb 1 1999, In : International Journal of Obesity. 23, p. 29-36 8 p.

Research output: Contribution to journalArticle

Open Access
95 Scopus citations

Effects of obesity and stable weight reduction on UCP2 and UCP3 gene expression in humans

Vidal-Puig, A., Rosenbaum, M., Considine, R. C., Leibel, R. L., Dohm, G. L. & Lowell, B. B., 1999, In : Obesity Research. 7, 2, p. 133-140 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Leptin secretion in Cushing's syndrome: Preservation of diurnal rhythm and absent response to corticotropin-releasing hormone

Weise, M., Abad, V., Considine, R. V., Nieman, L. & Rother, K. I., 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 6, p. 2075-2079 5 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Pleiotropic cellular effects of leptin

Considine, R. V. & Caro, J. F., May 5 1999, In : Current Opinion in Endocrinology and Diabetes. 6, 2, p. 163-169 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Serum leptin during recovery following maximal incremental and prolonged exercise

Torjman, M. C., Zafeiridis, A., Paolone, A. M., Wilkerson, C. & Considine, R. V., 1999, In : International Journal of Sports Medicine. 20, 7, p. 444-450 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Serum leptin levels in women throughout pregnancy and the postpartum period and in women suffering spontaneous abortion

Lage, M., Garcia-Mayor, R. V., Tomé, M. A., Cordido, F., Valle-Inclan, F., Considine, R. V., Caro, J. F., Dieguez, C. & Casanueva, F. F., 1999, In : Clinical Endocrinology. 50, 2, p. 211-216 6 p.

Research output: Contribution to journalArticle

81 Scopus citations

Weight loss and leptin changes in individuals with type 2 diabetes

Williams, K. V., Mullen, M., Lang, W., Considine, R. V. & Wing, R. R., 1999, In : Obesity Research. 7, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
2000

Associations of leptin with body fat distribution and metabolic parameters in non-insulin-dependent diabetic patients: No effect of apolipoprotein E polymorphism

Wauters, M., Considine, R., Löfgren, A., Van Broeckhoven, C., Van der Auwera, J. C., De Leeuw, I. & Van Gaal, L., Jan 1 2000, In : Metabolism: Clinical and Experimental. 49, 6, p. 724-730 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Hexosamines regulate leptin production in human subcutaneous adipocytes

Considine, R. V., Cooksey, R. C., Williams, L. B., Fawcett, R. L., Zhang, P., Ambrosius, W. T., Whitfield, R. M., Jones, R., Inman, M., Huse, J. & McClain, D. A., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 10, p. 3551-3556 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Hexosamines stimulate leptin production in transgenic mice

Mcclain, D. A., Alexander, T., Cooksey, R. C. & Considine, R. V., 2000, In : Endocrinology. 141, 6, p. 1999-2002 4 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

Human leptin: From an adipocyte hormone to an endocrine mediator

Wauters, M., Considine, R. V. & Van Gaal, L. F., Jan 1 2000, In : European Journal of Endocrinology. 143, 3, p. 293-311 19 p.

Research output: Contribution to journalReview article

Open Access
385 Scopus citations

Intensity of acute exercise does not affect serum leptin concentrations in young men

Weltman, A., Pritzlaff, C. J., Wideman, L., Considine, R. V., Fryburg, D. A., Gutgesell, M. E., Hartman, M. L. & Veldhuis, J. D., 2000, In : Medicine and Science in Sports and Exercise. 32, 9, p. 1556-1561 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

Leptin production in adipocytes from morbidly obese subjects: Stimulation by dexamethasone, inhibition with troglitazone, and influence of gender

Williams, L. B., Fawcett, R. L., Waechter, A. S., Zhang, P., Kogon, B. E., Jones, R. M., Inman, M., Huse, J. & Considine, R. V., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 8, p. 2678-2684 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Localization of leptin receptor-like immunoreactivity in the corticotropes, somatotropes, and gonadotropes in the ovine anterior pituitary

Iqbal, J., Pompolo, S., Considine, R. V. & Clarke, I. J., Jan 1 2000, In : Endocrinology. 141, 4, p. 1515-1520 6 p.

Research output: Contribution to journalArticle

Open Access
111 Scopus citations

Tumor necrosis factor-α inhibits leptin production in subcutaneous and omental adipocytes from morbidly obese humans

Fawcett, R. L., Waechter, A. S., Williams, L. B., Zhang, P., Louie, R., Jones, R., Inman, M., Huse, J. & Considine, R. V., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 2, p. 530-535 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
2001

Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women

Wauters, M., Mertens, I., Chagnon, M., Rankinen, T., Considine, R. V., Chagnon, Y. C., Van Gaal, L. F. & Bouchard, C., May 20 2001, In : International Journal of Obesity. 25, 5, p. 714-720 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Regulation of Leptin Production

Considine, R. V., Dec 1 2001, In : Reviews in Endocrine and Metabolic Disorders. 2, 4, p. 357-363 7 p.

Research output: Contribution to journalArticle

84 Scopus citations

Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator - Activated Receptor-γ Action in Humans

Savage, D. B., Sewter, C. P., Klenk, E. S., Segal, D. G., Vidal-Puig, A., Considine, R. V. & O'Rahilly, S., Oct 2001, In : Diabetes. 50, 10, p. 2199-2202 4 p.

Research output: Contribution to journalArticle

Open Access
668 Scopus citations
2002

Differential effects of adiposity on peroxisomal proliferator-activated receptor γ1 and γ2 messenger ribonucleic acid expression in human adipocytes

Sewter, C., Blows, F., Considine, R., Vidal-Puig, A. & O'Rahilly, S., Sep 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 9, p. 4203-4207 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms

Zhang, P., Klenk, E. S., Lazzaro, M. A., Williams, L. B. & Considine, R. V., 2002, In : Endocrinology. 143, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α

Sewter, C., Berger, D., Considine, R. V., Medina, G., Rochford, J., Ciaraldi, T., Henry, R., Dohm, L., Flier, J. S., O'Rahilly, S. & Vidal-Puig, A. J., 2002, In : Diabetes. 51, 4, p. 1035-1041 7 p.

Research output: Contribution to journalArticle

Open Access
117 Scopus citations

Leptin levels, leptin receptor gene polymorphisms, and energy metabolism in women

Wauters, M., Considine, R. V., Chagnon, M., Mertens, I., Rankinen, T., Bouchard, C. & Van Gaal, L. F., May 2002, In : Obesity Research. 10, 5, p. 394-400 7 p.

Research output: Contribution to journalArticle

45 Scopus citations
2003

Does Leptin Play a Role in the Pathogenesis of Human Nonalcoholic Steatohepatitis?

Chalasani, N., Crabb, D. W., Cummings, O. W., Kwo, P. Y., Asghar, A., Pandya, P. K. & Considine, R. V., Dec 2003, In : American Journal of Gastroenterology. 98, 12, p. 2771-2776 6 p.

Research output: Contribution to journalArticle

125 Scopus citations

Leptin: From laboratory to clinic

Caro, J. F. & Considine, R. V., Jan 1 2003, Handbook of Obesity: Clinical Applications. CRC Press, p. 275-295 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Leptin levels in type 2 diabetes: Associations with measures of insulin resistance and insulin secretion

Wauters, M., Considine, R. V., Yudkin, J. S., Peiffer, F., De Leeuw, I. & Van Gaal, L. F., Feb 1 2003, In : Hormone and Metabolic Research. 35, 2, p. 92-96 5 p.

Research output: Contribution to journalArticle

77 Scopus citations

Lower serum adiponectin levels in African-American boys

Degawa-Yamauchi, M., Dilts, J. R., Bovenkerk, J. E., Saha, C., Pratt, J. H. & Considine, R. V., 2003, In : Obesity Research. 11, 11, p. 1384-1390 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Obesity is associated with increased levels of circulating hepatocyte growth factor

Rehman, J., Considine, R. V., Bovenkerk, J. E., Li, J., Slavens, C. A., Jones, R. M. & March, K. L., Apr 2003, In : Journal of the American College of Cardiology. 41, 8, p. 1408-1413 6 p.

Research output: Contribution to journalReview article

120 Scopus citations

Serum leptin responses after acute resistance exercise protocols

Zafeiridis, A., Smilios, I., Considine, R. V. & Tokmakidis, S. P., Feb 1 2003, In : Journal of Applied Physiology. 94, 2, p. 591-597 7 p.

Research output: Contribution to journalArticle

52 Scopus citations

Serum Resistin (FIZZ3) Protein Is Increased in Obese Humans

Degawa-Yamauchi, M., Bovenkerk, J. E., Juliar, B. E., Watson, W., Kerr, K., Jones, R., Zhu, Q. & Considine, R. V., Nov 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 11, p. 5452-5455 4 p.

Research output: Contribution to journalArticle

383 Scopus citations
2004

Changes in thrombolytic and inflammatory markers after initiation of indinavir- or amprenavir-based antiretroviral therapy

Young, E. M., Considine, R. V., Sattler, F. R., Deeg, M. A., Buchanan, T. A., Degawa-Yamauchi, M., Shankar, S., Edmondson-Melançon, H., Hernandez, J. & Dubé, M. P., Oct 14 2004, In : Cardiovascular Toxicology. 4, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Erratum: High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians (Diabetes (2004) 53 (1279-1284))

Vozarova De Courten, B., Degawa-Yamauchi, M., Considine, R. V. & Tataranni, P. A., Sep 1 2004, In : Diabetes. 53, 9, 1 p.

Research output: Contribution to journalComment/debate