Robert Considine

  • 22396 Citations
  • 68 h-Index
1976 …2020

Research output per year

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Publications

Effects of obesity and stable weight reduction on UCP2 and UCP3 gene expression in humans

Vidal-Puig, A., Rosenbaum, M., Considine, R. C., Leibel, R. L., Dohm, G. L. & Lowell, B. B., 1999, In : Obesity Research. 7, 2, p. 133-140 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Erratum: High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians (Diabetes (2004) 53 (1279-1284))

Vozarova De Courten, B., Degawa-Yamauchi, M., Considine, R. V. & Tataranni, P. A., Sep 1 2004, In : Diabetes. 53, 9, 1 p.

Research output: Contribution to journalComment/debate

Ethanol impairs differentiation of human adipocyte stromal cells in culture

Crabb, D. W., Zeng, Y., Liangpunsakul, S., Jones, R. M. & Considine, R., Sep 2011, In : Alcoholism: Clinical and Experimental Research. 35, 9, p. 1584-1592 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

Considine, R. V., Considine, E. L., Williams, C. J., Nyce, M. R., Magosin, S. A., Bauer, T. L., Rosato, E. L., Colberg, J. & Caro, J. F., Jun 1995, In : Journal of Clinical Investigation. 95, 6, p. 2986-2988 3 p.

Research output: Contribution to journalArticle

Open Access
417 Scopus citations

Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects

Semple, R. K., Crowley, V. C., Sewter, C. P., Laudes, M., Christodoulides, C., Considine, R. V., Vidal-Puig, A. & O'Rahilly, S., Jan 1 2004, In : International Journal of Obesity. 28, 1, p. 176-179 4 p.

Research output: Contribution to journalArticle

143 Scopus citations

Failure of hyperglycemia and hyperinsulinemia to compensate for impaired metabolic response to an oral glucose load

Hussain, M., Janghorbani, M., Schuette, S., Considine, R. V., Chisholm, R. L. & Mather, K. J., Mar 1 2015, In : Journal of Diabetes and its Complications. 29, 2, p. 238-244 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Family history of alcoholism and the human brain response to oral sucrose

Eiler, W. J. A., Dzemidzic, M., Soeurt, C. M., Carron, C. R., Oberlin, B. G., Considine, R. V., Harezlak, J. & Kareken, D. A., Jan 1 2018, In : NeuroImage: Clinical. 17, p. 1036-1046 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle

Habegger, K. M., Penque, B. A., Sealls, W., Tackett, L., Bell, L. N., Blue, E. K., Gallagher, P. J., Sturek, M., Alloosh, M. A., Steinberg, H. O., Considine, R. V. & Elmendorf, J. S., Feb 1 2012, In : Diabetologia. 55, 2, p. 457-467 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Food-related odor probes of brain reward circuits during hunger: a pilot FMRI study.

Bragulat, V., Dzemidzic, M., Bruno, C., Cox, C. A., Talavage, T., Considine, R. V. & Kareken, D. A., Aug 2010, In : Obesity (Silver Spring, Md.). 18, 8, p. 1566-1571 6 p.

Research output: Contribution to journalArticle

76 Scopus citations

Gender-dependent effects of exercise training on serum leptin levels in humans

Hickey, M. S., Houmard, J. A., Considine, R. V., Tyndall, G. L., Midgette, J. B., Gavigan, K. E., Weidner, M. L., McCammon, M. R., Israel, R. G. & Caro, J. F., Apr 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 272, 4 35-4, p. E562-E566

Research output: Contribution to journalArticle

171 Scopus citations

Gender differences in serum leptin levels in humans

Hickey, M. S., Israel, R. G., Gardiner, S. N., Considine, R. V., McCammon, M. R., Tyndall, G. L., Houmard, J. A., Marks, R. H. L. & Caro, J. F., Oct 1996, In : Biochemical and Molecular Medicine. 59, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

189 Scopus citations

Genetic and environmental influences on the prospective correlation between systemic inflammation and coronary heart disease death in male twins

Wu, S. H., Neale, M. C., Acton, A. J., Considine, R. V., Krasnow, R. E., Reed, T. & Dai, J., Sep 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 9, p. 2168-2174 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic variation of GPLD1 associates with serum GPI-PLD levels: A preliminary study

Deeg, M. A., Xuei, X., Eckert, G., Considine, R. V., Li, Y. G. & Pratt, J. H., Mar 2012, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1821, 3, p. 381-385 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hemostasis and fibrinolysis in non-diabetic overweight and obese men and women. Is there still a role for leptin?

Mertens, I., Considine, R. V., Van der Planken, M. & Van Gaal, L. F., Sep 2006, In : European Journal of Endocrinology. 155, 3, p. 477-484 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Hepatocyte growth factor regulates neovascularization in developing fat pads

White, H. M., Acton, A. J., Kamocka, M. M. & Considine, R. V., Jan 15 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 2, p. E189-E196

Research output: Contribution to journalArticle

4 Scopus citations

Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms

Zhang, P., Klenk, E. S., Lazzaro, M. A., Williams, L. B. & Considine, R. V., 2002, In : Endocrinology. 143, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Hexosamines regulate leptin production in human subcutaneous adipocytes

Considine, R. V., Cooksey, R. C., Williams, L. B., Fawcett, R. L., Zhang, P., Ambrosius, W. T., Whitfield, R. M., Jones, R., Inman, M., Huse, J. & McClain, D. A., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 10, p. 3551-3556 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Hexosamines stimulate leptin production in transgenic mice

Mcclain, D. A., Alexander, T., Cooksey, R. C. & Considine, R. V., 2000, In : Endocrinology. 141, 6, p. 1999-2002 4 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

High Serum Resistin Is Associated with an Increase in Adiposity but Not a Worsening of Insulin Resistance in Pima Indians

De Courten, B. V., Degawa-Yamauchi, M., Considine, R. V. & Tataranni, P. A., May 2004, In : Diabetes. 53, 5, p. 1279-1284 6 p.

Research output: Contribution to journalArticle

143 Scopus citations

Human leptin: From an adipocyte hormone to an endocrine mediator

Wauters, M., Considine, R. V. & Van Gaal, L. F., Jan 1 2000, In : European Journal of Endocrinology. 143, 3, p. 293-311 19 p.

Research output: Contribution to journalReview article

Open Access
385 Scopus citations

Human leptin: An adipocyte hormone with weight-regulatory and endocrine functions

Considine, R. V., 2005, In : Seminars in Vascular Medicine. 5, 1, p. 15-24 10 p.

Research output: Contribution to journalReview article

73 Scopus citations

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α

Sewter, C., Berger, D., Considine, R. V., Medina, G., Rochford, J., Ciaraldi, T., Henry, R., Dohm, L., Flier, J. S., O'Rahilly, S. & Vidal-Puig, A. J., 2002, In : Diabetes. 51, 4, p. 1035-1041 7 p.

Research output: Contribution to journalArticle

Open Access
117 Scopus citations

Hyperinsulinemia fails to augment ET-1 action in the skeletal muscle vascular bed in vivo in humans

Lteif, A. A., Fulford, A. D., Considine, R. V., Gelfand, I., Baron, A. D. & Mather, K. J., Dec 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 6, p. E1510-E1517

Research output: Contribution to journalArticle

14 Scopus citations

Impaired cardiometabolic responses to glucagon-like peptide 1 in obesity and type 2 diabetes mellitus

Moberly, S. P., Mather, K. J., Berwick, Z. C., Owen, M. K., Goodwill, A. G., Casalini, E. D., Hutchins, G. D., Green, M. A., Ng, Y., Considine, R. V., Perry, K. M., Chisholm, R. L. & Tune, J. D., 2013, In : Basic Research in Cardiology. 108, 4, 365.

Research output: Contribution to journalArticle

35 Scopus citations

Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue

Ahmad, F., Considine, R. V., Bauer, T. L., Ohannesian, J. P., Marco, C. C. & Goldstein, B. J., Jan 1 1997, In : Metabolism: Clinical and Experimental. 46, 10, p. 1140-1145 6 p.

Research output: Contribution to journalArticle

110 Scopus citations
Open Access
111 Scopus citations

Increased serum leptin indicates leptin resistance in obesity

Considine, R. V., Oct 1 2011, In : Clinical chemistry. 57, 10, p. 1461-1462 2 p.

Research output: Contribution to journalComment/debate

4 Scopus citations
2 Scopus citations

Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats

Carro, E., Pinilla, L., Seoane, L. M., Considine, R. V., Aguilar, E., Casanueva, F. F. & Dieguez, C., Jan 1 1997, In : Neuroendocrinology. 66, 6, p. 375-377 3 p.

Research output: Contribution to journalArticle

142 Scopus citations

Inhibition of murine macrophage protein kinase C activity by nonviable Histoplasma capsulatum

Wolf, J. E., Massof, S. E., Sherwin, J. R. & Considine, R. V., Jan 1 1992, In : Infection and immunity. 60, 7, p. 2683-2687 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
Open Access

In situ type I oligomeric collagen macroencapsulation promotes islet longevity and function in vitro and in vivo

Stephens, C. H., Orr, K. S., Acton, A. J., Tersey, S. A., Mirmira, R. G., Considine, R. V. & Voytik-Harbin, S. L., Oct 6 2018, In : American Journal of Physiology - Endocrinology and Metabolism. 315, 4, p. E650-E661

Research output: Contribution to journalArticle

10 Scopus citations

Insulin and endothelin in the acute regulation of adiponectin in vivo in humans

Brame, L. A., Considine, R. V., Yamauchi, M., Baron, A. D. & Mather, K. J., 2005, In : Obesity Research. 13, 3, p. 582-588 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Insulin infusion reduces hepatocyte growth factor in lean humans

De Courten, B., De Courten, M. P. J., Dougherty, S., Forbes, J. M., Potts, J. R. & Considine, R. V., May 1 2013, In : Metabolism: Clinical and Experimental. 62, 5, p. 647-650 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Insulin Resistance Is Associated with Increased Serum Levels of Glycosylphosphatidylinositol-Specific Phospholipase D

Kurtz, T. A., Fineberg, N. S., Considine, R. V. & Deeg, M. A., Feb 2004, In : Metabolism: Clinical and Experimental. 53, 2, p. 138-139 2 p.

Research output: Contribution to journalArticle

20 Scopus citations

Insulin sensitivity is preserved despite disrupted endothelial function

Shankar, S. S., Considine, R. V., Gorski, J. C. & Steinberg, H. O., 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 291, 4, p. E691-E696

Research output: Contribution to journalArticle

14 Scopus citations

Intensity of acute exercise does not affect serum leptin concentrations in young men

Weltman, A., Pritzlaff, C. J., Wideman, L., Considine, R. V., Fryburg, D. A., Gutgesell, M. E., Hartman, M. L. & Veldhuis, J. D., 2000, In : Medicine and Science in Sports and Exercise. 32, 9, p. 1556-1561 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

Interaction between leptin and neuropeptide Y on in vivo growth hormone secretion

Carro, E., Seoane, L. M., Señaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., Sep 28 1998, In : Neuroendocrinology. 68, 3, p. 187-191 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Interleukin 1α increases serum leptin concentrations in humans

Janik, J. E., Curti, B. D., Considine, R. V., Rager, H. C., Powers, G. C., Alvord, W. G., Smith, J. W., Gause, B. L. & Kopp, W. C., Sep 24 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 3084-3086 3 p.

Research output: Contribution to journalArticle

206 Scopus citations

Invited editorial on 'acute and chronic effects of exercise on leptin levels in humans'

Considine, R. V., Jan 1 1997, In : Journal of Applied Physiology. 83, 1, p. 3-4 2 p.

Research output: Contribution to journalReview article

24 Scopus citations

In vitro effect of endotoxin on lipolysis and lipoprotein lipase activity in adipocytes from lean, obese and obese diabetic Zucker rats

Lanza-Jacoby, S., Rose, G. L., Rosato, E. F., Sedkova, N. & Considine, R. V., Dec 1995, In : Journal of Endotoxin Research. 2, 6, p. 449-454 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study

Vuppalanchi, R., Marri, S., Kolwankar, D., Considine, R. V. & Chalasani, N., Mar 2005, In : Journal of Clinical Gastroenterology. 39, 3, p. 237-242 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Leptin: From laboratory to clinic

Caro, J. F. & Considine, R. V., Jan 1 2003, Handbook of Obesity: Clinical Applications. CRC Press, p. 275-295 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Leptin

Morgan, R. C. & Considine, R. V., Jan 1 2018, Encyclopedia of Endocrine Diseases. Elsevier, p. 420-427 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Leptin: The tale of an obesity gene

Caro, J. F., Sinha, M. K., Kolaczynski, J. W., Zhang, P. L. & Considine, R. V., Jan 1 1996, In : Diabetes. 45, 11, p. 1455-1462 8 p.

Research output: Contribution to journalReview article

886 Scopus citations

Leptin: Genes, concepts and clinical perspective

Considine, R. V. & Caro, J. F., Jan 1 1996, In : Hormone Research in Paediatrics. 46, 6, p. 249-256 8 p.

Research output: Contribution to journalArticle

77 Scopus citations

Leptin and intermediary metabolism: Focus on glucoregulation and lipids

Morgan, R. C. & Considine, R. V., Jan 1 2015, Leptin: Regulation and Clinical Applications. Springer International Publishing, p. 79-88 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Leptin and the regulation of body weight

Considine, R. V. & Caro, J. F., Nov 1 1997, In : International Journal of Biochemistry and Cell Biology. 29, 11, p. 1255-1272 18 p.

Research output: Contribution to journalReview article

164 Scopus citations

Leptin in humans: current progress and future directions.

Considine, R. V. & Caro, J. F., Jun 1996, In : Clinical chemistry. 42, 6 Pt 1, p. 843-844 2 p.

Research output: Contribution to journalComment/debate

Open Access
24 Scopus citations

Leptin is related to body fat content in male distance runners

Hickey, M. S., Considine, R. V., Israel, R. G., Mahar, T. L., Mccammon, M. R., Tyndall, G. L., Houmard, J. A. & Caro, J. F., Nov 1996, In : American Journal of Physiology - Endocrinology and Metabolism. 271, 5 34-5, p. E938-E940

Research output: Contribution to journalArticle

141 Scopus citations