Robert Considine

  • 22342 Citations
  • 68 h-Index
1976 …2020

Research output per year

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Publications

2000

Hexosamines regulate leptin production in human subcutaneous adipocytes

Considine, R. V., Cooksey, R. C., Williams, L. B., Fawcett, R. L., Zhang, P., Ambrosius, W. T., Whitfield, R. M., Jones, R., Inman, M., Huse, J. & McClain, D. A., Jan 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 10, p. 3551-3556 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Hexosamines stimulate leptin production in transgenic mice

Mcclain, D. A., Alexander, T., Cooksey, R. C. & Considine, R. V., Jan 1 2000, In : Endocrinology. 141, 6, p. 1999-2002 4 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

Human leptin: From an adipocyte hormone to an endocrine mediator

Wauters, M., Considine, R. V. & Van Gaal, L. F., Jan 1 2000, In : European Journal of Endocrinology. 143, 3, p. 293-311 19 p.

Research output: Contribution to journalReview article

Open Access
385 Scopus citations

Intensity of acute exercise does not affect serum leptin concentrations in young men

Weltman, A., Pritzlaff, C. J., Wideman, L., Considine, R. V., Fryburg, D. A., Gutgesell, M. E., Hartman, M. L. & Veldhuis, J. D., Jan 1 2000, In : Medicine and Science in Sports and Exercise. 32, 9, p. 1556-1561 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

Leptin production in adipocytes from morbidly obese subjects: Stimulation by dexamethasone, inhibition with troglitazone, and influence of gender

Williams, L. B., Fawcett, R. L., Waechter, A. S., Zhang, P., Kogon, B. E., Jones, R. M., Inman, M., Huse, J. & Considine, R. V., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 8, p. 2678-2684 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Localization of leptin receptor-like immunoreactivity in the corticotropes, somatotropes, and gonadotropes in the ovine anterior pituitary

Iqbal, J., Pompolo, S., Considine, R. V. & Clarke, I. J., Jan 1 2000, In : Endocrinology. 141, 4, p. 1515-1520 6 p.

Research output: Contribution to journalArticle

Open Access
111 Scopus citations

Tumor necrosis factor-α inhibits leptin production in subcutaneous and omental adipocytes from morbidly obese humans

Fawcett, R. L., Waechter, A. S., Williams, L. B., Zhang, P., Louie, R., Jones, R., Inman, M., Huse, J. & Considine, R. V., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 2, p. 530-535 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
1999

An overview and update of the physiology of leptin in humans

Considine, R. V., Jun 1 1999, In : Journal of Clinical Ligand Assay. 22, 2, p. 233-235 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical endocrinology of human leptin

Van Gaal, L. F., Wauters, M. A., Mertens, I. L., Considine, R. V. & De Leeuw, I. H., Feb 1 1999, In : International Journal of Obesity. 23, p. 29-36 8 p.

Research output: Contribution to journalArticle

Open Access
94 Scopus citations

Effects of obesity and stable weight reduction on UCP2 and UCP3 gene expression in humans

Vidal-Puig, A., Rosenbaum, M., Considine, R. C., Leibel, R. L., Dohm, G. L. & Lowell, B. B., Jan 1 1999, In : Obesity Research. 7, 2, p. 133-140 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Leptin secretion in Cushing's syndrome: Preservation of diurnal rhythm and absent response to corticotropin-releasing hormone

Weise, M., Abad, V., Considine, R. V., Nieman, L. & Rother, K. I., Jan 1 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 6, p. 2075-2079 5 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Pleiotropic cellular effects of leptin

Considine, R. V. & Caro, J. F., May 5 1999, In : Current Opinion in Endocrinology and Diabetes. 6, 2, p. 163-169 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Serum leptin during recovery following maximal incremental and prolonged exercise

Torjman, M. C., Zafeiridis, A., Paolone, A. M., Wilkerson, C. & Considine, R. V., Oct 28 1999, In : International Journal of Sports Medicine. 20, 7, p. 444-450 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Serum leptin levels in women throughout pregnancy and the postpartum period and in women suffering spontaneous abortion

Lage, M., Garcia-Mayor, R. V., Tomé, M. A., Cordido, F., Valle-Inclan, F., Considine, R. V., Caro, J. F., Dieguez, C. & Casanueva, F. F., Mar 5 1999, In : Clinical Endocrinology. 50, 2, p. 211-216 6 p.

Research output: Contribution to journalArticle

81 Scopus citations

Weight loss and leptin changes in individuals with type 2 diabetes

Williams, K. V., Mullen, M., Lang, W., Considine, R. V. & Wing, R. R., Jan 1 1999, In : Obesity Research. 7, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
1998

Acute changes in free-fatty acids (FFA) do not alter serum leptin levels

Peinò, R., Fernández Alvarez, J., Peñalva, A., Considine, R. V., Rodriguez-Segade, S., Rodriguez-Garcia, J., Cordido, F., Casanueva, F. F. & Dieguez, C., Sep 1998, In : Journal of Endocrinological Investigation. 21, 8, p. 526-530 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

A new paradigm for type 2 diabetes mellitus: Could it be a disease of the foregut?

Hickey, M. S., Pories, W. J., MacDonald, K. G., Cory, K. A., Dohm, G. L., Swanson, M. S., Israel, R. G., Barakat, H. A., Considine, R. V., Caro, J. F. & Houmard, J. A., May 1 1998, In : Annals of surgery. 227, 5, p. 637-644 8 p.

Research output: Contribution to journalArticle

227 Scopus citations

Are leptin levels dependent on body fat distribution in obese men and women?

Wauters, M., Mertens, I., Considine, R., De Leeuw, I. & Van Gaal, L., Sep 1998, In : Eating and weight disorders : EWD. 3, 3, p. 124-130 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Association of leptin and hunger-satiety ratings in obese women

Heini, A. F., Lara-Castro, C., Kirk, K. A., Considine, R. V., Caro, J. F. & Weinsier, R. L., Jan 1 1998, In : International Journal of Obesity. 22, 11, p. 1084-1087 4 p.

Research output: Contribution to journalArticle

Open Access
68 Scopus citations

Effect of hydrolyzed guar fiber on fasting and postprandial satiety and satiety hormones: A double-blind, placebo-controlled trial during controlled weight loss

Heini, A. F., Lara-Castro, C., Schneider, H., Kirk, K. A., Considine, R. V. & Weinsier, R. L., Jan 1 1998, In : International Journal of Obesity. 22, 9, p. 906-909 4 p.

Research output: Contribution to journalArticle

58 Scopus citations

Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children

Klein, K. O., Larmore, K. A., De Lancey, E., Brown, J. M., Considine, R. V. & Hassink, S. G., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 10, p. 3469-3475 7 p.

Research output: Contribution to journalArticle

Open Access
189 Scopus citations

Interaction between leptin and neuropeptide Y on in vivo growth hormone secretion

Carro, E., Seoane, L. M., Señaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., Sep 28 1998, In : Neuroendocrinology. 68, 3, p. 187-191 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Serum leptin levels and energy expenditure in normal weight women

Martin, L. J., Jones, P. J. H., Considine, R. V., Su, W., Boyd, N. F. & Caro, J. F., Jan 1 1998, In : Canadian Journal of Physiology and Pharmacology. 76, 2, p. 237-241 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Short- and long-term changes in serum leptin in dieting obese women: Effects of caloric restriction and weight loss

Wadden, T. A., Considine, R. V., Foster, G. D., Anderson, D. A., Sarwer, D. B. & Caro, J. S., Nov 12 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 1, p. 214-218 5 p.

Research output: Contribution to journalArticle

110 Scopus citations

The Ob protein (leptin) and the kidney

Sharma, K. & Considine, R. V., Jan 1 1998, In : Kidney international. 53, 6, p. 1483-1487 5 p.

Research output: Contribution to journalArticle

58 Scopus citations
1997

Dexamethasone, OB gene, and leptin in humans; Effect of exogenous hyperinsulinemia

Kolaczynski, J. W., Goldstein, B. J. & Considine, R. V., Jan 1 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 11, p. 3895-3897 3 p.

Research output: Contribution to journalArticle

55 Scopus citations

Dexamethasone stimulates leptin release from human adipocytes: Unexpected inhibition by insulin

Considine, R. V., Nyce, M. R., Kolaczynski, J. W., Zhang, P. L., Ohannesian, J. P., Moore, J. H., Fox, J. W. & Caro, J. F., May 1 1997, In : Journal of Cellular Biochemistry. 65, 2, p. 254-258 5 p.

Research output: Contribution to journalArticle

86 Scopus citations

Effect of weight loss and subsequent exercise training on serum leptin levels in obese humans

Cory, K. A., Tanner, C. J., Morgan, L. J., Tripp, B. L., Dohm, G. L., Pories, W. J., Barakat, H. A., Considine, R. V., Houmard, J. A., Caro, J. F. & Hickey, M. S., Dec 1 1997, In : Sports Medicine, Training and Rehabilitation. 8, 1, p. 97-98 2 p.

Research output: Contribution to journalArticle

Gender-dependent effects of exercise training on serum leptin levels in humans

Hickey, M. S., Houmard, J. A., Considine, R. V., Tyndall, G. L., Midgette, J. B., Gavigan, K. E., Weidner, M. L., McCammon, M. R., Israel, R. G. & Caro, J. F., Apr 1 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 272, 4 35-4, p. E562-E566

Research output: Contribution to journalArticle

171 Scopus citations

Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue

Ahmad, F., Considine, R. V., Bauer, T. L., Ohannesian, J. P., Marco, C. C. & Goldstein, B. J., Jan 1 1997, In : Metabolism: Clinical and Experimental. 46, 10, p. 1140-1145 6 p.

Research output: Contribution to journalArticle

109 Scopus citations

Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats

Carro, E., Pinilla, L., Seoane, L. M., Considine, R. V., Aguilar, E., Casanueva, F. F. & Dieguez, C., Jan 1 1997, In : Neuroendocrinology. 66, 6, p. 375-377 3 p.

Research output: Contribution to journalArticle

142 Scopus citations

Interleukin 1α increases serum leptin concentrations in humans

Janik, J. E., Curti, B. D., Considine, R. V., Rager, H. C., Powers, G. C., Alvord, W. G., Smith, J. W., Gause, B. L. & Kopp, W. C., Sep 24 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 3084-3086 3 p.

Research output: Contribution to journalArticle

204 Scopus citations

Invited editorial on 'acute and chronic effects of exercise on leptin levels in humans'

Considine, R. V., Jan 1 1997, In : Journal of Applied Physiology. 83, 1, p. 3-4 2 p.

Research output: Contribution to journalReview article

24 Scopus citations

Leptin and the regulation of body weight

Considine, R. V. & Caro, J. F., Nov 1 1997, In : International Journal of Biochemistry and Cell Biology. 29, 11, p. 1255-1272 18 p.

Research output: Contribution to journalReview article

164 Scopus citations

Leptin plasma levels in healthy Spanish children and adolescents, children with obesity, and adolescents anorexia nervosa and bulimia nervosa

Argente, J., Barrios, I., Chowen, J. A., Sinha, M. K. & Considine, R. V., Jan 1 1997, In : Journal of Pediatrics. 131, 6, p. 833-838 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

Leptin receptors in the adrenal medulla of the rat

Cao, G. Y., Considine, R. V. & Lynn, R. B., 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 273, 2 36-2, p. E448-E452

Research output: Contribution to journalArticle

67 Scopus citations

Nocturnal rise of leptin in normal prepubertal and pubertal children and in patients with perinatal stalk-transection syndrome

Pombo, M., Herrera-Justiniano, E., Considine, R. V., Hermida, R. C., Galvez, M. J., Martin, T., Barreiro, J., Casanueva, F. F. & Dieguez, C., Jan 1 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 8, p. 2751-2754 4 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

Vidal-Puig, A. J., Considine, R. V., Jimenez-Liñan, M., Werman, A., Pories, W. J., Caro, J. F. & Flier, J. S., May 15 1997, In : Journal of Clinical Investigation. 99, 10, p. 2416-2422 7 p.

Research output: Contribution to journalArticle

Open Access
677 Scopus citations

Placental leptin: an important new growth factor in intrauterine and neonatal development?

Hassink, S. G., de Lancey, E., Sheslow, D. V., Smith-Kirwin, S. M., O'Connor, D. M., Considine, R. V., Opentanova, I., Dostal, K., Spear, M. L., Leef, K., Ash, M., Spitzer, A. R. & Funanage, V. L., Jul 1997, In : Pediatrics. 100, 1, p. E1

Research output: Contribution to journalArticle

250 Scopus citations

Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients

Sharma, K., Considine, R. V., Michael, B., Dunn, S. R., Weisberg, L. S., Kurnik, B. R. C., Kurnik, P. B., O'Connor, J., Sinha, M. & Caro, J. F., Jan 1 1997, In : Kidney international. 51, 6, p. 1980-1985 6 p.

Research output: Contribution to journalArticle

Open Access
222 Scopus citations

Regulation of in vivo growth hormone secretion by leptin

Carro, E., Senaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., May 8 1997, In : Endocrinology. 138, 5, p. 2203-2206 4 p.

Research output: Contribution to journalArticle

328 Scopus citations

Serum immunoreactive leptin concentrations in patients with anorexia nervosa before and after partial weight recovery

Casanueva, F. F., Dieguez, C., Popovic, V., Peino, R., Considine, R. V. & Caro, J. F., Apr 1997, In : Biochemical and Molecular Medicine. 60, 2, p. 116-120 5 p.

Research output: Contribution to journalArticle

74 Scopus citations

Serum leptin concentrations in patients with anorexia nervosa, bulimia nervosa and non-specific eating disorders correlate with the body mass index but are independent of the respective disease

Ferron, F., Considine, R. V., Peino, R., Lado, I. G., Dieguez, C. & Casanueva, F. F., Jan 1 1997, In : Clinical Endocrinology. 46, 3, p. 289-293 5 p.

Research output: Contribution to journalArticle

109 Scopus citations

Synthesis of leptin in human placenta

Señarís, R., Garcia-Caballero, T., Casabiell, X., Gallego, R., Castro, R., Considine, R. V., Dieguez, C. & Casanueva, F. F., Jan 1 1997, In : Endocrinology. 138, 10, p. 4501-4504 4 p.

Research output: Contribution to journalArticle

Open Access
316 Scopus citations

Weight regulation, leptin and growth hormone

Considine, R. V., Jan 1 1997, In : Hormone Research in Paediatrics. 48, 5, p. 116-121 6 p.

Research output: Contribution to journalArticle

69 Scopus citations
1996

Acute and chronic effect of insulin on leptin production in humans: Studies in vivo and in vitro

Kolaczynski, J. W., Nyce, M. R., Considine, R. V., Boden, G., Nolan, J. J., Henry, R., Mudaliar, S. R., Olefsky, J. & Caro, J. F., May 1996, In : Diabetes. 45, 5, p. 699-701 3 p.

Research output: Contribution to journalArticle

Open Access
735 Scopus citations

Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice

Lynn, R. B., Cao, G. Y., Considine, R. V., Hyde, T. M. & Caro, J. F., Feb 27 1996, In : Biochemical and Biophysical Research Communications. 219, 3, p. 884-889 6 p.

Research output: Contribution to journalArticle

110 Scopus citations

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance

Caro, J. F., Kolaczynski, J. W., Nyce, M. R., Ohannesian, J. P., Opentanova, I., Goldman, W. H., Lynn, R. B., Zhang, P. L., Sinha, M. K. & Considine, R. V., Jul 20 1996, In : Lancet. 348, 9021, p. 159-161 3 p.

Research output: Contribution to journalArticle

995 Scopus citations

Do leptin receptors play a functional role in the endocrine pancreas?

Leclercq-Meyer, V., Considine, R. V., Sener, A. & Malaisse, W. J., Dec 24 1996, In : Biochemical and Biophysical Research Communications. 229, 3, p. 794-798 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

Effect of troglitazone on leptin production: Studies in vitro and in human subjects

Nolan, J. J., Olefsky, J. M., Nyce, M. R., Considine, R. V. & Caro, J. F., Jan 1 1996, In : Diabetes. 45, 9, p. 1276-1278 3 p.

Research output: Contribution to journalArticle

116 Scopus citations