Robert Considine

  • 22342 Citations
  • 68 h-Index
1976 …2020

Research output per year

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Publications

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1998

Association of leptin and hunger-satiety ratings in obese women

Heini, A. F., Lara-Castro, C., Kirk, K. A., Considine, R. V., Caro, J. F. & Weinsier, R. L., Jan 1 1998, In : International Journal of Obesity. 22, 11, p. 1084-1087 4 p.

Research output: Contribution to journalArticle

Open Access
68 Scopus citations

Effect of hydrolyzed guar fiber on fasting and postprandial satiety and satiety hormones: A double-blind, placebo-controlled trial during controlled weight loss

Heini, A. F., Lara-Castro, C., Schneider, H., Kirk, K. A., Considine, R. V. & Weinsier, R. L., Jan 1 1998, In : International Journal of Obesity. 22, 9, p. 906-909 4 p.

Research output: Contribution to journalArticle

58 Scopus citations

Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children

Klein, K. O., Larmore, K. A., De Lancey, E., Brown, J. M., Considine, R. V. & Hassink, S. G., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 10, p. 3469-3475 7 p.

Research output: Contribution to journalArticle

Open Access
189 Scopus citations

Interaction between leptin and neuropeptide Y on in vivo growth hormone secretion

Carro, E., Seoane, L. M., Señaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., Sep 28 1998, In : Neuroendocrinology. 68, 3, p. 187-191 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Serum leptin levels and energy expenditure in normal weight women

Martin, L. J., Jones, P. J. H., Considine, R. V., Su, W., Boyd, N. F. & Caro, J. F., Jan 1 1998, In : Canadian Journal of Physiology and Pharmacology. 76, 2, p. 237-241 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Short- and long-term changes in serum leptin in dieting obese women: Effects of caloric restriction and weight loss

Wadden, T. A., Considine, R. V., Foster, G. D., Anderson, D. A., Sarwer, D. B. & Caro, J. S., Nov 12 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 1, p. 214-218 5 p.

Research output: Contribution to journalArticle

110 Scopus citations

The Ob protein (leptin) and the kidney

Sharma, K. & Considine, R. V., Jan 1 1998, In : Kidney international. 53, 6, p. 1483-1487 5 p.

Research output: Contribution to journalArticle

58 Scopus citations
1997

Dexamethasone, OB gene, and leptin in humans; Effect of exogenous hyperinsulinemia

Kolaczynski, J. W., Goldstein, B. J. & Considine, R. V., Jan 1 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 11, p. 3895-3897 3 p.

Research output: Contribution to journalArticle

55 Scopus citations

Dexamethasone stimulates leptin release from human adipocytes: Unexpected inhibition by insulin

Considine, R. V., Nyce, M. R., Kolaczynski, J. W., Zhang, P. L., Ohannesian, J. P., Moore, J. H., Fox, J. W. & Caro, J. F., May 1 1997, In : Journal of Cellular Biochemistry. 65, 2, p. 254-258 5 p.

Research output: Contribution to journalArticle

86 Scopus citations

Effect of weight loss and subsequent exercise training on serum leptin levels in obese humans

Cory, K. A., Tanner, C. J., Morgan, L. J., Tripp, B. L., Dohm, G. L., Pories, W. J., Barakat, H. A., Considine, R. V., Houmard, J. A., Caro, J. F. & Hickey, M. S., Dec 1 1997, In : Sports Medicine, Training and Rehabilitation. 8, 1, p. 97-98 2 p.

Research output: Contribution to journalArticle

Gender-dependent effects of exercise training on serum leptin levels in humans

Hickey, M. S., Houmard, J. A., Considine, R. V., Tyndall, G. L., Midgette, J. B., Gavigan, K. E., Weidner, M. L., McCammon, M. R., Israel, R. G. & Caro, J. F., Apr 1 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 272, 4 35-4, p. E562-E566

Research output: Contribution to journalArticle

171 Scopus citations

Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue

Ahmad, F., Considine, R. V., Bauer, T. L., Ohannesian, J. P., Marco, C. C. & Goldstein, B. J., Jan 1 1997, In : Metabolism: Clinical and Experimental. 46, 10, p. 1140-1145 6 p.

Research output: Contribution to journalArticle

109 Scopus citations

Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats

Carro, E., Pinilla, L., Seoane, L. M., Considine, R. V., Aguilar, E., Casanueva, F. F. & Dieguez, C., Jan 1 1997, In : Neuroendocrinology. 66, 6, p. 375-377 3 p.

Research output: Contribution to journalArticle

142 Scopus citations

Interleukin 1α increases serum leptin concentrations in humans

Janik, J. E., Curti, B. D., Considine, R. V., Rager, H. C., Powers, G. C., Alvord, W. G., Smith, J. W., Gause, B. L. & Kopp, W. C., Sep 24 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 3084-3086 3 p.

Research output: Contribution to journalArticle

204 Scopus citations

Leptin plasma levels in healthy Spanish children and adolescents, children with obesity, and adolescents anorexia nervosa and bulimia nervosa

Argente, J., Barrios, I., Chowen, J. A., Sinha, M. K. & Considine, R. V., Jan 1 1997, In : Journal of Pediatrics. 131, 6, p. 833-838 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

Leptin receptors in the adrenal medulla of the rat

Cao, G. Y., Considine, R. V. & Lynn, R. B., 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 273, 2 36-2, p. E448-E452

Research output: Contribution to journalArticle

67 Scopus citations

Nocturnal rise of leptin in normal prepubertal and pubertal children and in patients with perinatal stalk-transection syndrome

Pombo, M., Herrera-Justiniano, E., Considine, R. V., Hermida, R. C., Galvez, M. J., Martin, T., Barreiro, J., Casanueva, F. F. & Dieguez, C., Jan 1 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 8, p. 2751-2754 4 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

Vidal-Puig, A. J., Considine, R. V., Jimenez-Liñan, M., Werman, A., Pories, W. J., Caro, J. F. & Flier, J. S., May 15 1997, In : Journal of Clinical Investigation. 99, 10, p. 2416-2422 7 p.

Research output: Contribution to journalArticle

Open Access
677 Scopus citations

Placental leptin: an important new growth factor in intrauterine and neonatal development?

Hassink, S. G., de Lancey, E., Sheslow, D. V., Smith-Kirwin, S. M., O'Connor, D. M., Considine, R. V., Opentanova, I., Dostal, K., Spear, M. L., Leef, K., Ash, M., Spitzer, A. R. & Funanage, V. L., Jul 1997, In : Pediatrics. 100, 1, p. E1

Research output: Contribution to journalArticle

250 Scopus citations

Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients

Sharma, K., Considine, R. V., Michael, B., Dunn, S. R., Weisberg, L. S., Kurnik, B. R. C., Kurnik, P. B., O'Connor, J., Sinha, M. & Caro, J. F., Jan 1 1997, In : Kidney international. 51, 6, p. 1980-1985 6 p.

Research output: Contribution to journalArticle

Open Access
222 Scopus citations

Regulation of in vivo growth hormone secretion by leptin

Carro, E., Senaris, R., Considine, R. V., Casanueva, F. F. & Dieguez, C., May 8 1997, In : Endocrinology. 138, 5, p. 2203-2206 4 p.

Research output: Contribution to journalArticle

328 Scopus citations

Serum immunoreactive leptin concentrations in patients with anorexia nervosa before and after partial weight recovery

Casanueva, F. F., Dieguez, C., Popovic, V., Peino, R., Considine, R. V. & Caro, J. F., Apr 1997, In : Biochemical and Molecular Medicine. 60, 2, p. 116-120 5 p.

Research output: Contribution to journalArticle

74 Scopus citations

Serum leptin concentrations in patients with anorexia nervosa, bulimia nervosa and non-specific eating disorders correlate with the body mass index but are independent of the respective disease

Ferron, F., Considine, R. V., Peino, R., Lado, I. G., Dieguez, C. & Casanueva, F. F., Jan 1 1997, In : Clinical Endocrinology. 46, 3, p. 289-293 5 p.

Research output: Contribution to journalArticle

109 Scopus citations

Synthesis of leptin in human placenta

Señarís, R., Garcia-Caballero, T., Casabiell, X., Gallego, R., Castro, R., Considine, R. V., Dieguez, C. & Casanueva, F. F., Jan 1 1997, In : Endocrinology. 138, 10, p. 4501-4504 4 p.

Research output: Contribution to journalArticle

Open Access
316 Scopus citations

Weight regulation, leptin and growth hormone

Considine, R. V., Jan 1 1997, In : Hormone Research in Paediatrics. 48, 5, p. 116-121 6 p.

Research output: Contribution to journalArticle

69 Scopus citations
1996

Acute and chronic effect of insulin on leptin production in humans: Studies in vivo and in vitro

Kolaczynski, J. W., Nyce, M. R., Considine, R. V., Boden, G., Nolan, J. J., Henry, R., Mudaliar, S. R., Olefsky, J. & Caro, J. F., May 1996, In : Diabetes. 45, 5, p. 699-701 3 p.

Research output: Contribution to journalArticle

Open Access
735 Scopus citations

Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice

Lynn, R. B., Cao, G. Y., Considine, R. V., Hyde, T. M. & Caro, J. F., Feb 27 1996, In : Biochemical and Biophysical Research Communications. 219, 3, p. 884-889 6 p.

Research output: Contribution to journalArticle

110 Scopus citations

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance

Caro, J. F., Kolaczynski, J. W., Nyce, M. R., Ohannesian, J. P., Opentanova, I., Goldman, W. H., Lynn, R. B., Zhang, P. L., Sinha, M. K. & Considine, R. V., Jul 20 1996, In : Lancet. 348, 9021, p. 159-161 3 p.

Research output: Contribution to journalArticle

995 Scopus citations

Do leptin receptors play a functional role in the endocrine pancreas?

Leclercq-Meyer, V., Considine, R. V., Sener, A. & Malaisse, W. J., Dec 24 1996, In : Biochemical and Biophysical Research Communications. 229, 3, p. 794-798 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

Effect of troglitazone on leptin production: Studies in vitro and in human subjects

Nolan, J. J., Olefsky, J. M., Nyce, M. R., Considine, R. V. & Caro, J. F., 1996, In : Diabetes. 45, 9, p. 1276-1278 3 p.

Research output: Contribution to journalArticle

116 Scopus citations

Gender differences in serum leptin levels in humans

Hickey, M. S., Israel, R. G., Gardiner, S. N., Considine, R. V., McCammon, M. R., Tyndall, G. L., Houmard, J. A., Marks, R. H. L. & Caro, J. F., Oct 1996, In : Biochemical and Molecular Medicine. 59, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

189 Scopus citations

Leptin: Genes, concepts and clinical perspective

Considine, R. V. & Caro, J. F., Jan 1 1996, In : Hormone Research in Paediatrics. 46, 6, p. 249-256 8 p.

Research output: Contribution to journalArticle

77 Scopus citations

Leptin is related to body fat content in male distance runners

Hickey, M. S., Considine, R. V., Israel, R. G., Mahar, T. L., Mccammon, M. R., Tyndall, G. L., Houmard, J. A. & Caro, J. F., Nov 1996, In : American Journal of Physiology - Endocrinology and Metabolism. 271, 5 34-5, p. E938-E940

Research output: Contribution to journalArticle

141 Scopus citations

Mutation screening and identification of a sequence variation in the human ob gene coding region

Considine, R. V., Considine, E. L., Williams, C. J., Nyce, M. R., Zhang, P., Opentanova, I., Ohannesian, J. P., Kolaczynski, J. W., Bauer, T. L., Moore, J. H. & Caro, J. F., Mar 27 1996, In : Biochemical and Biophysical Research Communications. 220, 3, p. 735-739 5 p.

Research output: Contribution to journalArticle

81 Scopus citations

Paracrine stimulation of preadipocyte-enriched cell cultures by mature adipocytes

Considine, R. V., Nyce, M. R., Morales, L. M., Magosin, S. A., Sinha, M. K., Bauer, T. L., Rosato, E. L., Colberg, J. & Caro, J. F., 1996, In : American Journal of Physiology - Endocrinology and Metabolism. 270, 5 33-5, p. E895-E899

Research output: Contribution to journalArticle

40 Scopus citations

Relationship between weight loss maintenance and changes in serum leptin levels

Wing, R. R., Sinha, M. K., Considine, R. V., Lang, W. & Caro, J. F., 1996, In : Hormone and Metabolic Research. 28, 12, p. 698-703 6 p.

Research output: Contribution to journalArticle

98 Scopus citations

Response of leptin to short-term and prolonged overfeeding in humans

Kolaczynski, J. W., Ohannesian, J. P., Considine, R. V., Marco, C. C. & Caro, J. F., Nov 23 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 11, p. 4162-4165 4 p.

Research output: Contribution to journalArticle

352 Scopus citations

Responses of leptin to short-term fasting and refeeding in humans: A link with ketogenesis but not ketones themselves

Kolaczynski, J. W., Considine, R. V., Ohannesian, J., Marco, C., Opentanova, I., Nyce, M. R., Myint, M. & Caro, J. F., Jan 1 1996, In : Diabetes. 45, 11, p. 1511-1515 5 p.

Research output: Contribution to journalArticle

454 Scopus citations

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., Mckee, L. J., Bauer, T. L. & Caro, J. F., Feb 1 1996, In : New England Journal of Medicine. 334, 5, p. 292-295 4 p.

Research output: Contribution to journalArticle

5137 Scopus citations

Serum immunoreactive-leptin levels are increased in patients with Cushing's syndrome

Leal-Cerro, A., Considine, R. V., Peino, R., Venegas, E., Astorga, R., Casanueva, F. F. & Dieguez, C., Jan 1 1996, In : Hormone and Metabolic Research. 28, 12, p. 711-713 3 p.

Research output: Contribution to journalArticle

96 Scopus citations

Serum leptin in children with obesity: Relationship to gender and development

Hassink, S. G., Sheslow, D. V., De Lancey, E., Opentanova, I., Considine, R. V. & Caro, J. F., Aug 1 1996, In : Pediatrics. 98, 2, p. 201-203 3 p.

Research output: Contribution to journalArticle

359 Scopus citations

The hypothalamic leptin receptor in humans: Identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations

Considine, R. V., Considine, E. L., Williams, C. J., Hyde, T. M. & Caro, J. F., 1996, In : Diabetes. 45, 3 SUPPL., p. 992-994 3 p.

Research output: Contribution to journalArticle

241 Scopus citations
1995

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

Considine, R. V., Considine, E. L., Williams, C. J., Nyce, M. R., Magosin, S. A., Bauer, T. L., Rosato, E. L., Colberg, J. & Caro, J. F., Jun 1995, In : Journal of Clinical Investigation. 95, 6, p. 2986-2988 3 p.

Research output: Contribution to journalArticle

Open Access
417 Scopus citations
Open Access
111 Scopus citations

In vitro effect of endotoxin on lipolysis and lipoprotein lipase activity in adipocytes from lean, obese and obese diabetic Zucker rats

Lanza-Jacoby, S., Rose, G. L., Rosato, E. F., Sedkova, N. & Considine, R. V., Dec 1995, In : Journal of Endotoxin Research. 2, 6, p. 449-454 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: An alteration not due to hyperglycemia

Considine, R. V., Nyce, M. R., Allen, L. E., Morales, L. M., Triester, S., Serrano, J., Colberg, J., Lanza-Jacoby, S. & Caro, J. F., Jun 1995, In : Journal of Clinical Investigation. 95, 6, p. 2938-2944 7 p.

Research output: Contribution to journalArticle

Open Access
131 Scopus citations

Viability of fat obtained by syringe suction lipectomy: effects of local anesthesia with lidocaine

Moore, J. H., Kolaczynski, J. W., Morales, L. M., Considine, R. V., Pietrzkowski, Z., Noto, P. F. & Caro, J. F., Jul 1 1995, In : Aesthetic Plastic Surgery. 19, 4, p. 335-339 5 p.

Research output: Contribution to journalArticle

130 Scopus citations
1994

A new technique for biopsy of human abdominal fat under local anaesthesia with Lidocaine

Kolaczynski, J. W., Morales, L. M., Moore, J. H., Considine, R. V., Pietrzkowski, Z., Noto, P. F., Colberg, J. & Caro, J. F., Jan 1 1994, In : International Journal of Obesity. 18, 3, p. 161-166 6 p.

Research output: Contribution to journalArticle

96 Scopus citations

Cellular responses to acute injury: The role of the plasma membrane in cell response to two clostridial toxins

Sherwin, J. R. & Considine, R. V., Mar 1994, In : Journal of Voice. 8, 1, p. 65-69 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clostridial neurotoxins in the age of molecular medicine

Coffeld, J. A., Considine, R. V. & Simpson, L. L., Mar 1994, In : Trends in Microbiology. 2, 3, p. 67-69 3 p.

Research output: Contribution to journalArticle

9 Scopus citations