Robert Harris

  • 12148 Citations
  • 62 h-Index
1963 …2019
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  • 3 Similar Profiles
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) Medicine & Life Sciences
Rats Chemical Compounds
Liver Medicine & Life Sciences
Pyruvic Acid Medicine & Life Sciences
Pyruvate Dehydrogenase Complex Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences
Phosphorylation Chemical Compounds

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NIH Grants 1977 2012

Publications 1963 2019

  • 12148 Citations
  • 62 h-Index
  • 319 Article
  • 3 Chapter
4 Citations (Scopus)

PDK4 augments ER–mitochondria contact to dampen skeletal muscle insulin signaling during obesity

Thoudam, T., Ha, C. M., Leem, J., Chanda, D., Park, J. S., Kim, H. J., Jeon, J. H., Choi, Y. K., Liangpunsakul, S., Huh, Y. H., Kwon, T. H., Park, K. G., Harris, R., Park, K. S., Rhee, H. W. & Lee, I. K., Mar 1 2019, In : Diabetes. 68, 3, p. 571-586 16 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Mitochondria
Skeletal Muscle
Obesity
Insulin
2 Citations (Scopus)

PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia

Pin, F., Novinger, L. J., Huot, J. R., Harris, R., Couch, M. E., O'Connell, T. M. & Bonetto, A., Jun 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 6, p. 7778-7790 13 p.

Research output: Contribution to journalArticle

Cachexia
Muscular Atrophy
Muscle
Skeletal Muscle Fibers
Neoplasms
3 Citations (Scopus)

Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype

Min, B. K., Park, S., Kang, H. J., Kim, D. W., Ham, H. J., Ha, C. M., Choi, B. J., Lee, J. Y., Oh, C. J., Yoo, E. K., Kim, H. E., Kim, B. G., Jeon, J. H., Hyeon, D. Y., Hwang, D., Kim, Y. H., Lee, C. H., Lee, T., Kim, J. W., Choi, Y. K. & 5 others, Park, K. G., Chawla, A., Lee, J., Harris, R. & Lee, I. K., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Macrophages
Phenotype
Pyruvic Acid
Insulin Resistance
Obesity

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα

Naiman, S., Huynh, F. K., Gil, R., Glick, Y., Shahar, Y., Touitou, N., Nahum, L., Avivi, M. Y., Roichman, A., Kanfi, Y., Gertler, A. A., Doniger, T., Ilkayeva, O. R., Abramovich, I., Yaron, O., Lerrer, B., Gottlieb, E., Harris, R. A., Gerber, D., Hirschey, M. D. & 1 others, Cohen, H. Y., Dec 17 2019, In : Cell Reports. 29, 12, p. 4127-4143.e8

Research output: Contribution to journalArticle

Open Access
Peroxisome Proliferator-Activated Receptors
Metabolic Networks and Pathways
Pyruvic Acid
Fasting
Fatty Acids
1 Citation (Scopus)

Ca2+-dependent inhibition of branched-chain α-ketoacid dehydrogenase kinase by thiamine pyrophosphate

Noguchi, S., Kondo, Y., Ito, R., Katayama, T., Kazama, S., Kadota, Y., Kitaura, Y., Harris, R. & Shimomura, Y., Oct 12 2018, In : Biochemical and Biophysical Research Communications. 504, 4, p. 916-920 5 p.

Research output: Contribution to journalArticle

thiamin-diphosphate kinase
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Thiamine Pyrophosphate
Phosphotransferases
Branched Chain Amino Acids