Roberto Pili

  • 10704 Citations
  • 51 h-Index
1990 …2019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1990 2019

1990
5 Citations (Scopus)

Psychological status of institutionalized aged: Influences on immune parameters and endocrinological correlates

Bartoloni, C., Guidi, L., Antico, L., Pili, R., Cursi, F., Carbonin, P., Gambassi, G., Rumi, C., Di Giovanni, A., Menichella, G., Menini, E., Doria, D. F. G. & Doria, G., 1990, In : International Journal of Neuroscience. 51, 3-4, p. 279-281 3 p.

Research output: Contribution to journalArticle

Psychiatric Status Rating Scales
Lymphocyte Subsets
Delayed Hypersensitivity
Lymphocyte Activation
Natural Killer Cells
1991
14 Citations (Scopus)

Immune parameters in a populatio of institutionalized elderly subjects: influence of depressive disorders and endocrinological correlations

Bartoloni, C., Guidi, L., Frasca, D., Antico, L., Pili, R., Cursi, F., Di Giovanni, A., Rumi, C., Menini, E., Carbonin, P., Doria, G. & Gambassi, G., 1991, In : Mechanisms of Ageing and Development. 60, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Lymphocytes
Depressive Disorder
Hydrocortisone
Endorphins
Adrenocorticotropic Hormone
36 Citations (Scopus)

Impairment of lymphocyte activities in depressed aged subjects

Guidi, L., Bartoloni, C., Frasca, D., Antico, L., Pili, R., Cursi, F., Tempesta, E., Rumi, C., Menini, E., Carbonin, P., Doria, G. & Gambassi, G., 1991, In : Mechanisms of Ageing and Development. 60, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

Lymphocytes
Interleukin-2
Depression
Psychology
Depressive Disorder
4 Citations (Scopus)

Psychological status and immunological parameters of institutionalized aged.

Bartoloni, C., Guidi, L., Antico, L., Pariante, C. M., Di Giovanni, A., Pili, R., Cursi, F., Tricerri, A., Tempesta, E. & Frasca, D., Jul 1991, In : Panminerva Medica. 33, 3, p. 164-169 6 p.

Research output: Contribution to journalArticle

Phytohemagglutinins
Psychology
Lymphocytes
Delayed Hypersensitivity
Lymphocyte Activation
3 Citations (Scopus)

Valutazione di alterazioni latenti della coagulazione mediante il dosaggio plasmatico del complesso trombina antitrombina nelle neoplasie gastrointestinali.

Translated title of the contribution: Evaluation of latent changes in blood coagulation by the determination of plasma thrombin-antithrombin complex in gastrointestinal neoplasmsGuidi, L., Bartoloni, C., Pellicanò, P., Cappelli, A., Cursi, F., Pili, R., Tricerri, A., Patriarca, F. & Gambassi, G., Mar 31 1991, In : Clinica Terapeutica. 136, 6, p. 367-373 7 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Blood Coagulation
Neoplasms
Enzyme-Linked Immunosorbent Assay
antithrombin III-protease complex
1992
9 Citations (Scopus)

Latent coagulation disorders evaluated by the assay of plasma thrombin-antithrombin III complexes in a large series of 'solid tumours'

Bartoloni, C., Guidi, L., Tricerri, A., Patriarca, F., Pili, R., Cursi, F., Canetta, M., Cappelli, A., Vangeli, M., Salvati, F. & Gambassi, G., 1992, In : Oncology. 49, 6, p. 426-430 5 p.

Research output: Contribution to journalArticle

Neoplasms
Blood Coagulation Disorders
Gastrointestinal Neoplasms
antithrombin III-protease complex
Non-Small Cell Lung Carcinoma
728 Citations (Scopus)

Methods in laboratory investigation: A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor

Passaniti, A., Taylor, R. M., Pili, R., Guo, Y., Long, P. V., Haney, J. A., Pauly, R. R., Grant, D. S. & Martin, G. R., 1992, In : Laboratory Investigation. 67, 4, p. 519-528 10 p.

Research output: Contribution to journalArticle

Angiogenesis Inhibitors
Fibroblast Growth Factors
Basement Membrane
Heparin
Gels
1993
7 Citations (Scopus)

Assay, isolation and characterization of circulating immune complexes from serum of gastrointestinal cancer, stage III and IV melanoma and chronic inflammatory bowel disease patients

Bartoloni, C., Guidi, L., Pili, R., Lewis, Z. A., Tricerri, A., Cursi, F., Gentiloni, N., Cortesi, E. & Gambassi, G., 1993, In : Oncology. 50, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Antigen-Antibody Complex
Inflammatory Bowel Diseases
Immune Sera
Melanoma
18 Citations (Scopus)

Endothelial cell Ca2+ increases upon tumor cell contact and modulates cell-cell adhesion

Pili, R., Corda, S., Passaniti, A., Ziegelstein, R. C., Heldman, A. W. & Capogrossi, M. C., 1993, In : Journal of Clinical Investigation. 92, 6, p. 3017-3022 6 p.

Research output: Contribution to journalArticle

Cell Adhesion
Endothelial Cells
Neoplasms
Melanoma
Ethane

Endothelial cell Ca2+ is increased by melanoma cell adhesion

Pili, R., Ziegelstein, R. C., Passaniti, A. & Capogrossi, M. C., 1993, In : Clinical Chemistry and Enzymology Communications. 6, 1-2, p. 79-83 5 p.

Research output: Contribution to journalArticle

Cell adhesion
Endothelial cells
Cell Adhesion
Melanoma
Endothelial Cells
1 Citation (Scopus)

Psychological status, life and social conditions: A study in a population of institutionalized elderly people

Bartoloni, C., Guidi, L., di Giovanni, A. L., Antico, L., Cursi, F., Pili, R., Tricerri, A., Janiri, L., Mannelli, P., Pariante, C., Menini, E., Carbonin, P. & Gambassi, G., 1993, In : International Journal of Geriatric Psychiatry. 8, 5, p. 419-426 8 p.

Research output: Contribution to journalArticle

Social Conditions
Psychology
Hydrocortisone
Population
Institutionalization
1994
47 Citations (Scopus)

A functional ryanodine-sensitive intracellular Ca2+ store is present in vascular endothelial cells

Ziegelstein, R. C., Spurgeon, H. A., Pili, R., Passaniti, A., Cheng, L., Corda, S., Lakatta, E. G. & Capogrossi, M. C., 1994, In : Circulation Research. 74, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

Ryanodine
Endothelial Cells
Bradykinin
Aorta
Buffers
107 Citations (Scopus)

Altered angiogenesis underlying age-dependent changes in tumor growth

Pili, R., Guo, Y., Chang, J., Nakanishi, H., Martin, G. R. & Passaniti, A., Sep 7 1994, In : Journal of the National Cancer Institute. 86, 17, p. 1303-1314 12 p.

Research output: Contribution to journalArticle

Angiogenesis
Tumor Growth
Tumors
Tumor
Dependent
40 Citations (Scopus)

Initial contact and subsequent adhesion of human neutrophils or monocytes to human aortic endothelial cells releases an endothelial intracellular calcium store

Ziegelstein, R. C., Corda, S., Pili, R., Passaniti, A., Lefer, D., Zweier, J. L., Fraticelli, A. & Capogrossi, M. C., Oct 1994, In : Circulation. 90, 4 I, p. 1899-1907 9 p.

Research output: Contribution to journalArticle

Monocytes
Neutrophils
Leukocytes
Endothelial Cells
Calcium
22 Citations (Scopus)
Dihydrotestosterone
Prostate-Specific Antigen
Extracellular Matrix
Carcinoma
Gene Expression
1995
60 Citations (Scopus)

Adenovirus‐mediated gene transfer of wild‐type p53 results in melanoma cell apoptosis in vitro and in vivo

Cirielli, C., Riccioni, T., Yang, C., Pili, R., Gloe, T., Chang, J., Inyaku, K., Passaniti, A. & Capogrossi, M. C., 1995, In : International Journal of Cancer. 63, 5, p. 673-679 7 p.

Research output: Contribution to journalArticle

Melanoma
Apoptosis
Genes
Neoplasms
DNA Fragmentation
66 Citations (Scopus)

In vivo angiogenesis induced by recombinant adenovirus vectors coding either for secreted or nonsecreted forms of acidic fibroblast growth factor

Mühlhauser, J., Pili, R., Merrill, M. J., Maeda, H., Passaniti, A., Crystal, R. G. & Capogrossi, M. C., Nov 1995, In : Human Gene Therapy. 6, 11, p. 1457-1465 9 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Adenoviridae
Galactosidases
Angiogenesis Inducing Agents
Human Umbilical Vein Endothelial Cells
169 Citations (Scopus)

The α-Glucosidase I Inhibitor Castanospermine Alters Endothelial Cell Glycosylation, Prevents Angiogenesis, and Inhibits Tumor Growth

Pili, R., Chang, J., Partis, R. A., Mueller, R. A., Chrest, F. J. & Passaniti, A., Jul 1 1995, In : Cancer Research. 55, 13, p. 2920-2926 7 p.

Research output: Contribution to journalArticle

Glycosylation
Endothelial Cells
Mannose
Glucosidases
Oligosaccharides
146 Citations (Scopus)

VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo

Muhlhauser, J., Merrill, M. J., Pili, R., Maeda, H., Bacic, M., Bewig, B., Passaniti, A., Edwards, N. A., Crystal, R. G. & Capogrossi, M. C., 1995, In : Circulation Research. 77, 6, p. 1077-1086 10 p.

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Adenoviridae
Vascular Endothelial Growth Factor A
Smooth Muscle Myocytes
Aorta
1997
6 Citations (Scopus)

Adenovirus-mediated gene transfer of fibroblast growth factor-1: Angiogenesis and tumorigenicity in nude mice

Pili, R., Chang, J., Muhlhauser, J., Crystal, R. G., Capogrossi, M. C. & Passaniti, A., 1997, In : International Journal of Cancer. 73, 2, p. 258-263 6 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Adenoviridae
Nude Mice
Genes
Growth
2001
114 Citations (Scopus)

Combination of phenylbutyrate and 13-cis retinoic acid inhibits prostate tumor growth and angiogenesis

Pili, R., Kruszewski, M. P., Hager, B. W., Lantz, J. & Carducci, M. A., Feb 15 2001, In : Cancer Research. 61, 4, p. 1477-1485 9 p.

Research output: Contribution to journalArticle

Phenylbutyrates
Isotretinoin
Prostate
Growth
Neoplasms
16 Citations (Scopus)

Modified synthesis and antiangiogenic activity of Linomide

Khan, S. R., Mhaka, A., Pili, R. & Isaacs, J. T., Feb 26 2001, In : Bioorganic and Medicinal Chemistry Letters. 11, 4, p. 451-452 2 p.

Research output: Contribution to journalArticle

Thermodynamic properties
Blood vessels
Microvessels
Blood Volume
Blood Vessels
2002
140 Citations (Scopus)

Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer

Sirchia, S. M., Ren, M., Pili, R., Sironi, E., Somenzi, G., Ghidoni, R., Toma, S., Nicolò, G. & Sacchi, N., May 1 2002, In : Cancer Research. 62, 9, p. 2455-2461 7 p.

Research output: Contribution to journalArticle

Retinoic Acid Receptors
Tumor Suppressor Genes
Breast Neoplasms
Chromatin
DNA Methylation
155 Citations (Scopus)

Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1

Volpert, O. V., Pili, R., Sikder, H. A., Nelius, T., Zaichuk, T., Morris, C., Shiflett, C. B., Devlin, M. K., Conant, K. & Alani, R. M., Dec 2002, In : Cancer Cell. 2, 6, p. 473-483 11 p.

Research output: Contribution to journalArticle

Thrombospondin 1
Embryonic Structures
Fibroblasts
Angiogenesis Inhibitors
Neutralizing Antibodies
2003
110 Citations (Scopus)

CEP-7055: A novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models

Ruggeri, B., Singh, J., Gingrich, D., Angeles, T., Albom, M., Chang, H., Robinson, C., Hunter, K., Dobrzanski, P., Jones-Bolin, S., Aimone, L., Klein-Szanto, A., Herbert, J. M., Bono, F., Schaeffer, P., Casellas, P., Bourie, B., Pili, R., Isaacs, J., Ator, M. & 4 others, Hudkins, R., Vaught, J., Mallamo, J. & Dionne, C., Sep 15 2003, In : Cancer Research. 63, 18, p. 5978-5991 14 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor
Protein-Tyrosine Kinases
Vascular Endothelial Growth Factor A
Phosphotransferases
Nude Mice

Erratum: CEP-7055: A Novel, Orally Active Pan Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases with Potent Antiangiogenic Activity and Antitumor Efficacy in Preclinical Models (Cancer Research (September 15, 2003) (5978-5991))

Ruggeri, B., Singh, J., Gingrich, D., Angeles, T., Albom, M., Yang, S., Chang, H., Robinson, C., Hunter, K., Dobrzanski, P., Jones-Bolin, S., Pritchard, S., Aimone, L., Klein-Szanto, A., Herbert, J. M., Bono, F., Schaeffer, P., Casellas, P., Bourie, B., Pili, R. & 6 others, Isaacs, J., Ator, M., Hudkins, R., Vaught, J., Mallamo, J. & Dionne, C., Nov 1 2003, In : Cancer Research. 63, 21, p. 7543 1 p.

Research output: Contribution to journalComment/debate

Vascular Endothelial Growth Factor Receptor
Protein-Tyrosine Kinases
Research
Neoplasms
N,N-dimethylglycine 3-(5,6,7,13-tetrahydro-9-((1-methylethoxy)methyl)-5-oxo-12H-indeno(2,1-a)pyrrolo(3,4-c)carbazol-12-yl)propyl ester
20 Citations (Scopus)

Is HIF-1α a valid therapeutic target?

Pili, R. & Donehower, R. C., Apr 2 2003, In : Journal of the National Cancer Institute. 95, 7, p. 498-499 2 p.

Research output: Contribution to journalEditorial

Alpha Subunit Hypoxia-Inducible Factor 1
Vascular Endothelial Growth Factors
Indazoles
Endothelial Growth Factors
Pathologic Neovascularization
2004
19 Citations (Scopus)

A new high affinity technetium analogue of bombesin containing DTPA as a pharmacokinetic modifier

Lin, K. S., Luu, A., Baidoo, K. E., Hashemzadeh-Gargari, H., Chen, M. K., Pili, R., Pomper, M., Carducci, M. & Wagner, H. N., Nov 2004, In : Bioconjugate Chemistry. 15, 6, p. 1416-1423 8 p.

Research output: Contribution to journalArticle

Technetium
Bombesin
Pharmacokinetics
Peptides
Bombesin Receptors
10 Citations (Scopus)

A Phase II Trial of Temozolomide and IFN-α in Patients with Advanced Renal Cell Carcinoma

Sunkara, U., Walczak, J. R., Summerson, L., Rogers, T., Eisenberger, M., Denmeade, S., Pili, R., Huff, C. A., Sinibaldi, V. & Carducci, M. A., Jan 2004, In : Journal of Interferon and Cytokine Research. 24, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

temozolomide
Renal Cell Carcinoma
Interferons
Chills
Melanoma
151 Citations (Scopus)

Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: Therapy with sequential 1-β -D-arabinofuranosylcytosine, mitoxantrone, and bevacizumab

Karp, J. E., Gojo, I., Pili, R., Gocke, C. D., Greer, J., Guo, C., Qian, D., Morris, L., Tidwell, M., Chen, H. & Zwiebel, J., Jun 1 2004, In : Clinical Cancer Research. 10, 11, p. 3577-3585 9 p.

Research output: Contribution to journalArticle

Mitoxantrone
Cytarabine
Acute Myeloid Leukemia
Vascular Endothelial Growth Factor A
Therapeutics
193 Citations (Scopus)

The histone deacetylase inhibitor NVP-LAQ824 Inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584

Qian, D. Z., Wang, X., Kachhap, S. K., Kato, Y., Wei, Y., Zhang, L., Atadja, P. & Pili, R., Sep 15 2004, In : Cancer Research. 64, 18, p. 6626-6634 9 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor
Histone Deacetylase Inhibitors
Protein-Tyrosine Kinases
Neoplasms
Vascular Endothelial Growth Factor A
2005
56 Citations (Scopus)

A new high affinity technetium-99m-bombesin analogue with low abdominal accumulation

Lin, K. S., Luu, A., Baidoo, K. E., Hashemzadeh-Gargari, H., Chen, M. K., Brenneman, K., Pili, R., Pomper, M., Carducci, M. A. & Wagner, H. N., Jan 2005, In : Bioconjugate Chemistry. 16, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Technetium
Bombesin
Peptides
Bombesin Receptors
Liver
48 Citations (Scopus)

A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

Heath, E. I., Gaskins, M., Pitot, H. C., Pili, R., Tan, W., Marschke, R., Liu, G., Hillman, D., Sarkar, F., Sheng, S., Erlichman, C. & Ivy, P., Sep 2005, In : Clinical Prostate Cancer. 4, 2, p. 138-141 4 p.

Research output: Contribution to journalReview article

tanespimycin
Androgen Receptors
Interleukin-6
Prostatic Neoplasms
Hormones
67 Citations (Scopus)

Epigenetic modulation of retinoic acid receptor β2 by the histone deacetylase inhibitor MS-275 in human renal cell carcinoma

Wang, X. F., Qian, D. Z., Ren, M., Kato, Y., Wei, Y., Zhang, L., Fansler, Z., Clark, D., Nakanishi, O. & Pili, R., May 1 2005, In : Clinical Cancer Research. 11, 9, p. 3535-3542 8 p.

Research output: Contribution to journalArticle

Retinoic Acid Receptors
Histone Deacetylase Inhibitors
Renal Cell Carcinoma
Epigenomics
Isotretinoin
34 Citations (Scopus)

In vivo imaging of retinoic acid receptor β2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells

Qian, D. Z., Ren, M., Wei, Y., Wang, X., Van De Geijn, F., Rasmussen, C., Nakanishi, O., Sacchi, N. & Pili, R., Jun 15 2005, In : Prostate. 64, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

Retinoic Acid Receptors
Histone Deacetylase Inhibitors
Retinoids
Transcriptional Activation
Prostatic Neoplasms
1 Citation (Scopus)

Kidney cancer: Clinical practice guidelines

Motzer, R. J., Carducci, M. A., Fishman, M., Hancock, S. L., Hauke, R. J., Hudes, G. R., Kantoff, P., Kuzel, T. M., Lange, P. H., Levine, E. G., Logothetis, C., Margolin, K. A., Pili, R., Pohar, K. S., Redman, B. G., Richey, S., Robertson, C. N., Samlowski, W. E., Sheinfeld, J. & Urban, D. A., Jan 2005, In : JNCCN Journal of the National Comprehensive Cancer Network. 3, 1, p. 84-93 10 p.

Research output: Contribution to journalReview article

Kidney Neoplasms
Practice Guidelines
Nephrectomy
Renal Cell Carcinoma
Neoplasms
42 Citations (Scopus)

Marimastat in the treatment of patients with biochemically relapsed prostate cancer: A prospective randomized, double-blind, phase I/II trial

Rosenbaum, E., Zahurak, M., Sinibaldi, V., Carducci, M. A., Pili, R., Laufer, M., DeWeese, T. L. & Eisenberger, M. A., Jun 15 2005, In : Clinical Cancer Research. 11, 12, p. 4437-4443 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Prostate-Specific Antigen
Therapeutics
Matrix Metalloproteinase Inhibitors
Poisons
16 Citations (Scopus)

Modeling the cost of management options for stage I nonseminomatous germ cell tumors: A decision tree analysis

Link, R. E., Allaf, M. E., Pili, R. & Kavoussi, L. R., 2005, In : Journal of Clinical Oncology. 23, 24, p. 5762-5773 12 p.

Research output: Contribution to journalArticle

Decision Trees
Decision Support Techniques
Costs and Cost Analysis
Drug Therapy
Nonseminomatous germ cell tumor
2006
237 Citations (Scopus)

Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1α

Qian, D. Z., Kachhap, S. K., Collis, S. J., Verheul, H. M. W., Carducci, M. A., Atadja, P. & Pili, R., Sep 1 2006, In : Cancer Research. 66, 17, p. 8814-8821 8 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Histone Deacetylases
Histone Deacetylase Inhibitors
Transcriptional Activation
Proteins
72 Citations (Scopus)

Identification of ABR-215050 as lead second generation quinoline-3- carboxamide anti-angiogenic agent for the treatment of prostate cancer

Isaacs, J. T., Pili, R., Qian, D. Z., Dalrymple, S. L., Garrison, J. B., Kyprianou, N., Björk, A., Olsson, A. & Leanderson, T., Dec 1 2006, In : Prostate. 66, 16, p. 1768-1778 11 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Growth
Multiple Sclerosis
Neoplasms
Clinical Trials
77 Citations (Scopus)

Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target

Chong, C. R., Qian, D. Z., Pan, F., Wei, Y., Pili, R., Sullivan, D. J. & Liu, J. O., May 4 2006, In : Journal of Medicinal Chemistry. 49, 9, p. 2677-2680 4 p.

Research output: Contribution to journalArticle

Inosine Monophosphate
Endothelial cells
Oxidoreductases
Endothelial Cells
Cell proliferation
164 Citations (Scopus)

Phase I dose escalation and pharmacokinetic study of enzastaurin, an oral protein kinase C beta inhibitor, in patients with advanced cancer

Carducci, M. A., Musib, L., Kies, M. S., Pili, R., Truong, M., Brahmer, J. R., Cole, P., Sullivan, R., Riddle, J., Schmidt, J., Enas, N., Sinha, V., Thornton, D. E. & Herbst, R. S., Sep 1 2006, In : Journal of Clinical Oncology. 24, 25, p. 4092-4099 8 p.

Research output: Contribution to journalArticle

Protein Kinase C beta
Pharmacokinetics
Neoplasms
Maximum Tolerated Dose
Head and Neck Neoplasms
14 Citations (Scopus)

Phase II evaluation of docetaxel plus exisulind in patients with androgen independent prostate carcinoma

Sinibaldi, V. J., Elza-Brown, K., Schmidt, J., Eisenberger, M. A., Rosenbaum, E., Denmeade, S. R., Pili, R., Walczak, J., Baker, S. D., Zahurak, M. & Carducci, M. A., Aug 2006, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 29, 4, p. 395-398 4 p.

Research output: Contribution to journalArticle

docetaxel
Androgens
Prostate
Carcinoma
Prostatic Neoplasms
221 Citations (Scopus)

Targeting tumor angiogenesis with histone deacetylase inhibitors: The hydroxamic acid derivative LBH589

Qian, D. Z., Kato, Y., Shabbeer, S., Wei, Y., Verheul, H. M. W., Salumbides, B., Sanni, T., Atadja, P. & Pili, R., Jan 15 2006, In : Clinical Cancer Research. 12, 2, p. 634-642 9 p.

Research output: Contribution to journalArticle

Hydroxamic Acids
Histone Deacetylase Inhibitors
Neoplasms
Acetylation
Human Umbilical Vein Endothelial Cells
2007
11 Citations (Scopus)

A liquid chromatography/tandem mass spectrometry assay to quantitate MS-275 in human plasma

Zhao, M., Rudek, M. A., Mnasakanyan, A., Hartke, C., Pili, R. & Baker, S. D., Jan 17 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 43, 2, p. 784-787 4 p.

Research output: Contribution to journalArticle

Plasma (human)
formic acid
Liquid chromatography
Tandem Mass Spectrometry
Liquid Chromatography
48 Citations (Scopus)

Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models

Qian, D. Z., Wei, Y. F., Wang, X., Kato, Y., Cheng, L. & Pili, R., Aug 1 2007, In : Prostate. 67, 11, p. 1182-1193 12 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Prostatic Neoplasms
Acetylation
Growth
Histones
43 Citations (Scopus)

Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma

Kato, Y., Salumbides, B. C., Wang, X. F., Qian, D. Z., Williams, S., Wei, Y., Sanni, T. B., Atadja, P. & Pili, R., Jan 2007, In : Molecular Cancer Therapeutics. 6, 1, p. 70-81 12 p.

Research output: Contribution to journalArticle

NSC 153174
Isotretinoin
Histone Deacetylase Inhibitors
Melanoma
Tretinoin
34 Citations (Scopus)

Phase II Study of Imatinib Mesylate in Patients with Prostate Cancer with Evidence of Biochemical Relapse After Definitive Radical Retropubic Prostatectomy or Radiotherapy

Bajaj, G. K., Zhang, Z., Garrett-Mayer, E., Drew, R., Sinibaldi, V., Pili, R., Denmeade, S. R., Carducci, M. A., Eisenberger, M. A. & DeWeese, T. L., Mar 2007, In : Urology. 69, 3, p. 526-531 6 p.

Research output: Contribution to journalArticle

Prostatectomy
Prostatic Neoplasms
Radiotherapy
Recurrence
Prostate-Specific Antigen
80 Citations (Scopus)

Platelets take up the monoclonal antibody bevacizumab

Verheul, H. M. W., Lolkema, M. P. J., Qian, D. Z., Hilkes, Y. H. A., Liapi, E., Akkerman, J. W. N., Pili, R. & Voest, E. E., Sep 15 2007, In : Clinical Cancer Research. 13, 18, p. 5341-5347 7 p.

Research output: Contribution to journalArticle

Blood Platelets
Monoclonal Antibodies
Vascular Endothelial Growth Factor A
Fluorescein-5-isothiocyanate
Bevacizumab
15 Citations (Scopus)

Preclinical and clinical studies with the multi-kinase inhibitor CEP-701 as treatment for prostate cancer demonstrate the inadequacy of PSA response as a primary endpoint

Collins, C., Carducci, M. A., Eisenberger, M. A., Isaacs, J. T., Partin, A. W., Pili, R., Sinibaldi, V. J., Walczak, J. S. & Denmeade, S. R., Sep 2007, In : Cancer Biology and Therapy. 6, 9, p. 1360-1367 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Phosphotransferases
Therapeutics
Prostate
Prostatectomy