Romil Saxena

  • 6124 Citations
  • 37 h-Index
1990 …2020

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Publications

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2020

A Comparative Study of 22G versus 19G Needles for EUS-Guided Biopsies for Parenchymal Liver Disease: Are Thinner Needles Better?

Patel, H. K., Saxena, R., Rush, N., Patel, S. K., Dasari, C. S., Mneimneh, W., Quickery, A., Rahal, M. A., Temnykh, L., DeWitt, J. & Al-Haddad, M., Jan 1 2020, (Accepted/In press) In : Digestive diseases and sciences.

Research output: Contribution to journalArticle

Increased Mast Cell Counts and Degranulation in Microscopic Colitis

Chi, Z., Xu, J. & Saxena, R., Jan 1 2020, In : Gastroenterology Research and Practice. 2020, 9089027.

Research output: Contribution to journalArticle

Open Access

Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis

Kyritsi, K., Chen, L., O’Brien, A., Francis, H., Hein, T. W., Venter, J., Wu, N., Ceci, L., Zhou, T., Zawieja, D., Gashev, A. A., Meng, F., Invernizzi, P., Fabris, L., Wu, C., Skill, N. J., Saxena, R., Liangpunsakul, S., Alpini, G. & Glaser, S. S., Mar 1 2020, In : Hepatology. 71, 3, p. 990-1008 19 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sestrin 3 Protects Against Diet-Induced Nonalcoholic Steatohepatitis in Mice Through Suppression of Transforming Growth Factor β Signal Transduction

Huang, M., Kim, H. G., Zhong, X., Dong, C., Zhang, B., Fang, Z., Zhang, Y., Lu, X., Saxena, R., Liu, Y., Zhang, C., Liangpunsakul, S. & Dong, X. C., Jan 1 2020, In : Hepatology. 71, 1, p. 76-92 17 p.

Research output: Contribution to journalArticle

1 Scopus citations
14 Scopus citations
2019

Clinicopathological features of He Shou Wu-induced liver injury: This ancient anti-aging therapy is not liver-friendly

Wang, Y., Wang, L., Saxena, R., Wee, A., Yang, R., Tian, Q., Zhang, J., Zhao, X. & Jia, J., Feb 1 2019, In : Liver International. 39, 2, p. 389-400 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC)

Zhou, T., Kyritsi, K., Wu, N., Francis, H., Yang, Z., Chen, L., O'Brien, A., Kennedy, L., Ceci, L., Meadows, V., Kusumanchi, P., Wu, C., Baiocchi, L., Skill, N. J., Saxena, R., Sybenga, A., Xie, L., Liangpunsakul, S., Meng, F., Alpini, G. & 1 others, Glaser, S., Oct 2019, In : EBioMedicine. 48, p. 130-142 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
7 Scopus citations

Metabolomic characterization of human model of liver rejection identifies aberrancies linked to cyclooxygenase (COX) and nitric oxide synthase (NOS)

Skill, N. J., Elliott, C. M., Ceballos, B., Saxena, R., Pepin, R., Bettcher, L., Ellensberg, M., Raftery, D., Maluccio, M. A., Ekser, B., Mangus, R. S. & Kubal, C. A., Jan 1 2019, In : Annals of transplantation. 24, p. 341-349 9 p.

Research output: Contribution to journalArticle

Non-obese histologically confirmed NASH patients with abnormal liver biochemistry have more advanced fibrosis

Wang, Q., You, H., Ou, X., Zhao, X., Sun, Y., Wang, M., Wang, P., Wang, Y., Duan, W., Wang, X., Wu, S., Kong, Y., Saxena, R., Gouw, A. S. H. & Jia, J., Nov 1 2019, In : Hepatology International. 13, 6, p. 766-776 11 p.

Research output: Contribution to journalArticle

2018

cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation

Brunt, E., Aishima, S., Clavien, P. A., Fowler, K., Goodman, Z., Gores, G., Gouw, A., Kagen, A., Klimstra, D., Komuta, M., Kondo, F., Miksad, R., Nakano, M., Nakanuma, Y., Ng, I., Paradis, V., Nyun Park, Y., Quaglia, A., Roncalli, M., Roskams, T. & 14 others, Sakamoto, M., Saxena, R., Sempoux, C., Sirlin, C., Stueck, A., Thung, S., Tsui, W. M. S., Wang, X. W., Wee, A., Yano, H., Yeh, M., Zen, Y., Zucman-Rossi, J. & Theise, N., Jul 2018, In : Hepatology. 68, 1, p. 113-126 14 p.

Research output: Contribution to journalArticle

60 Scopus citations

Drug-Induced Liver Injury—Perspectives from Pathology

Chopra, S. & Saxena, R., Jun 1 2018, In : Current Pharmacology Reports. 4, 3, p. 182-192 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Lower expression of tumor microRNA-26a is associated with higher recurrence in patients with hepatocellular carcinoma undergoing surgical treatment

Jones, K. R., Nabinger, S. C., Lee, S., Sahu, S. S., Althouse, S., Saxena, R., Johnson, M. S., Chalasani, N., Gawrieh, S. & Kota, J., Sep 1 2018, In : Journal of Surgical Oncology. 118, 3, p. 431-439 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation

Puppala, S., Li, C., Glenn, J. P., Saxena, R., Gawrieh, S., Quinn, A., Palarczyk, J., Dick, E. J., Nathanielsz, P. W. & Cox, L. A., Dec 1 2018, In : Journal of Physiology. 596, 23, p. 5823-5837 15 p.

Research output: Contribution to journalArticle

14 Scopus citations
2017

Hepatoblastoma

Sharma, D., Subbarao, G. & Saxena, R., Mar 1 2017, In : Seminars in Diagnostic Pathology. 34, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Introduction

Saxena, R., 2017, (Accepted/In press) In : Seminars in Diagnostic Pathology.

Research output: Contribution to journalArticle

Primary mesenchymal liver tumors of childhood

Saeed, O. & Saxena, R., Mar 1 2017, In : Seminars in Diagnostic Pathology. 34, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Role of Stereotactic Body Radiation Therapy Before Orthotopic Liver Transplantation: Retrospective Evaluation of Pathologic Response and Outcomes

Mannina, E. M., Cardenes, H. R., Lasley, F. D., Goodman, B., Zook, J., Althouse, S., Cox, J. A., Saxena, R., Tector, J. & Maluccio, M., Apr 1 2017, In : International Journal of Radiation Oncology Biology Physics. 97, 5, p. 931-938 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Variant differentiation patterns in primary liver carcinoma

Sempoux, C., Paradis, V. & Saxena, R., Mar 1 2017, In : Seminars in Diagnostic Pathology. 34, 2, p. 176-182 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis

Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium & Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium, Dec 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 12, p. 1831-1838.e3

Research output: Contribution to journalArticle

19 Scopus citations

Hepatic arterial buffer response: Pathologic evidence in non-cirrhotic human liver with extrahepatic portal vein thrombosis

Rush, N., Sun, H., Nakanishi, Y., Mneimneh, W., Kwo, P. Y. & Saxena, R., May 1 2016, In : Modern Pathology. 29, 5, p. 489-499 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Nodular regenerative hyperplasia after treatment with trastuzumab emtansine

Force, J., Saxena, R., Schneider, B., Storniolo, A. M., Sledge, G. W., Chalasani, N. & Vuppalanchi, R., Jan 20 2016, In : Journal of Clinical Oncology. 34, 3, p. e9-e12

Research output: Contribution to journalArticle

14 Scopus citations

Optimization of Perioperative Conditions to Prevent Ischemic Cholangiopathy in Donation After Circulatory Death Donor Liver Transplantation

Kubal, C., Mangus, R., Fridell, J., Saxena, R., Rush, N., Wingler, M., Ekser, B. & Tector, J., Apr 29 2016, (Accepted/In press) In : Transplantation.

Research output: Contribution to journalArticle

25 Scopus citations

Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria

Ekser, B., Mangus, R., Kubal, C. A., Fridell, J. A., Powelson, J. A., Nagaraju, S., Mihaylov, P., Phillips, C., Saxena, R. & Goggins, W. C., Jul 14 2016, (Accepted/In press) In : American Journal of Nephrology. p. 85-91 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Drug-induced liver injury

Fisher, K., Vuppalanchi, R. & Saxena, R., Jul 1 2015, In : Archives of Pathology and Laboratory Medicine. 139, 7, p. 876-887 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

Evaluation of 11C-Acetate and 18 F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma

Territo, P. R., Maluccio, M., Riley, A. A., McCarthy, B. P., Fletcher, J., Tann, M., Saxena, R. & Skill, N. J., May 16 2015, In : BMC Medical Imaging. 15, 1, 15.

Research output: Contribution to journalArticle

8 Scopus citations

Liver injury and fibrosis induced by dietary challenge in the ossabaw miniature swine

Liang, T., Alloosh, M., Bell, L. N., Fullenkamp, A., Saxena, R., Van Alstine, W., Bybee, P., Werling, K., Sturek, M., Chalasani, N. & Masuoka, H. C., May 15 2015, In : PloS one. 10, 5, 0124173.

Research output: Contribution to journalArticle

15 Scopus citations

One hundred thirteen consecutive transgastric liver biopsies for hepatic parenchymal diseases

Nakanishi, Y., Mneimneh, W. S., Sey, M., Al-Haddad, M., Dewitt, J. M. & Saxena, R., Jun 29 2015, In : American Journal of Surgical Pathology. 39, 7, p. 968-976 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pathophysiological role of microRNA-29 in pancreatic cancer stroma

Kwon, J. J., Nabinger, S. C., Vega, Z., Sahu, S. S., Alluri, R. K., Abdul-Sater, Z., Yu, Z., Gore, J., Nalepa, G., Saxena, R., Korc, M. & Kota, J., Jun 22 2015, In : Scientific reports. 5, 11450.

Research output: Contribution to journalArticle

40 Scopus citations

Pathophysiology and diseases of the proximal pathways of the biliary system

Nakanishi, Y. & Saxena, R., Jul 1 2015, In : Archives of Pathology and Laboratory Medicine. 139, 7, p. 858-866 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prospective monitoring of donor-specific anti-HLA antibodies after intestine/multivisceral transplantation: Significance of De novo antibodies

Kubal, C., Mangus, R., Saxena, R., Lobashevsky, A., Higgins, N., Fridell, J. & Tector, A. J., Aug 1 2015, In : Transplantation. 99, 8, p. e49-e56

Research output: Contribution to journalArticle

20 Scopus citations
2014

A de novo unclassified malignant spindle cell neoplasm of liver allograft

Clevenger, J. A., Saxena, R. & Idrees, M. T., Feb 1 2014, In : Archives of Pathology and Laboratory Medicine. 138, 2, p. 274-277 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Crossmatch-positive liver transplantation in patients receiving thymoglobulin-rituximab induction

Kubal, C. A., Mangus, R. S., Saxena, R., Lobashevsky, A., Higgins, N., Agarwal, A., Fridell, J. A. & Tector, A. J., Jan 15 2014, In : Transplantation. 97, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

HIV-1 coinfection profoundly alters intrahepatic chemokine but not inflammatory cytokine profiles in HCV-infected subjects

Hu, S., Ghabril, M., Amet, T., Hu, N., Byrd, D., Yang, K., Vuppalanchi, R., Saxena, R., Desai, M., Lan, J., Johnson, R., Gupta, S., Chalasani, N. & Yu, Q., Feb 6 2014, In : PLoS ONE. 9, 2, e86964.

Research output: Contribution to journalArticle

4 Scopus citations

Newborn with an underrecognized triad: Skin lesion, abdominal distention, and hypothyroidism

Sun, J., Karmazyn, B., Lin, J., Faught, P. R., Fan, R. & Saxena, R., Feb 2014, In : Journal of Pediatrics. 164, 2, p. 419-420 2 p.

Research output: Contribution to journalArticle

Serum hepcidin levels are associated with obesity but not liver disease

Vuppalanchi, R., Troutt, J. S., Konrad, R. J., Ghabril, M., Saxena, R., Bell, L. N., Kowdley, K. V. & Chalasani, N., Mar 2014, In : Obesity. 22, 3, p. 836-841 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Utility of pre-procurement bedside liver biopsy in the deceased extended-criteria liver donor

Mangus, R. S., Borup, T. C., Popa, S., Saxena, R., Cummings, O. & Tector, A. J., Dec 1 2014, In : Clinical Transplantation. 28, 12, p. 1358-1364 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

The usefulness of diffusion-weighted imaging in the characterization of liver lesions in patients with cirrhosis

Sandrasegaran, K., Tahir, B., Patel, A., Ramaswamy, R., Bertrand, K., Akisik, F. M. & Saxena, R., Jul 1 2013, In : Clinical Radiology. 68, 7, p. 708-715 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Alcohol Induces Liver Neoplasia in a Novel Alcohol-Preferring Rat Model

Yip-Schneider, M. T., Doyle, C. J., Mckillop, I. H., Wentz, S. C., Brandon-Warner, E., Matos, J. M., Sandrasegaran, K., Saxena, R., Hennig, M. E., Wu, H., Waters, J. A., Klein, P. J., Froehlich, J. C. & Max Schmidt, C., Dec 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 12, p. 2216-2225 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules

Ahn, M., Witting, S. R., Ruiz, R., Saxena, R. & Morral, N., Dec 1 2011, In : Human Gene Therapy. 22, 12, p. 1483-1497 15 p.

Research output: Contribution to journalArticle

10 Scopus citations

Diffusion-weighted MRI of the transplanted liver

Sandrasegaran, K., Ramaswamy, R., Ghosh, S., Tahir, B., Akisik, F. M., Saxena, R. & Kwo, P., Sep 1 2011, In : Clinical Radiology. 66, 9, p. 820-825 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Does the hepatocellular phase of gadobenate dimeglumine help to differentiate hepatocellular carcinoma in cirrhotic patients according to histological grade?

Tahir, B., Sandrasegaran, K., Ramaswamy, R., Bertrand, K., Mhapsekar, R., Akisik, F. M. & Saxena, R., Sep 1 2011, In : Clinical Radiology. 66, 9, p. 845-852 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effect of different obesogenic diets on pancreatic histology in Ossabaw miniature swine

Fullenkamp, A. M., Bell, L. N., Robbins, R. D., Lee, L., Saxena, R., Alloosh, M., Klaunig, J. E., Mirmira, R. G., Sturek, M. & Chalasani, N., Apr 1 2011, In : Pancreas. 40, 3, p. 438-443 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Hepatic lipid peroxidation and cytochrome P-450 2E1 in pediatric nonalcoholic fatty liver disease and its subtypes

Bell, L. N., Molleston, J. P., Morton, M. J., Klipsch, A., Saxena, R., Vuppalanchi, R. & Chalasani, N., Oct 1 2011, In : Journal of Clinical Gastroenterology. 45, 9, p. 800-807 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Oxidative stress in chronic liver disease: Relationship between peripheral and hepatic measurements

Vuppalanchi, R., Juluri, R., Bell, L. N., Ghabril, M., Kamendulis, L., Klaunig, J. E., Saxena, R., Agarwal, D., Johnson, M. S. & Chalasani, N., Oct 2011, In : American Journal of the Medical Sciences. 342, 4, p. 314-317 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Preface

Saxena, R., 2011, In : Unknown Journal.

Research output: Contribution to journalArticle

Utility of formalin-fixed, paraffin-embedded liver biopsy specimens for global proteomic analysis in nonalcoholic steatohepatitis

Bell, L. N., Saxena, R., Mattar, S. G., You, J., Wang, M. & Chalasani, N., Aug 1 2011, In : Proteomics - Clinical Applications. 5, 7-8, p. 397-404 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2010

Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

Wu, J. M., Xu, Y., Skill, N. J., Sheng, H., Zhao, Z., Yu, M., Saxena, R. & Maluccio, M. A., Mar 31 2010, In : Molecular Cancer. 9, 71.

Research output: Contribution to journalArticle

82 Scopus citations

Clonality and TP53 mutation analysis of focal nodular hyperplasia of the liver

Zheng, S., Cummings, O. W., Saxena, R., Zhang, S., Wang, M., Williamson, S. R., Cheng, M., Lopez-Beltran, A., Montironi, R., Hodges, K. B. & Cheng, L., Jul 1 2010, In : American journal of clinical pathology. 134, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

5 Scopus citations