Romil Saxena

  • 6128 Citations
  • 37 h-Index
1990 …2020

Research output per year

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Publications

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2010

Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

Wu, J. M., Xu, Y., Skill, N. J., Sheng, H., Zhao, Z., Yu, M., Saxena, R. & Maluccio, M. A., Mar 31 2010, In : Molecular Cancer. 9, 71.

Research output: Contribution to journalArticle

82 Scopus citations

Clonality and TP53 mutation analysis of focal nodular hyperplasia of the liver

Zheng, S., Cummings, O. W., Saxena, R., Zhang, S., Wang, M., Williamson, S. R., Cheng, M., Lopez-Beltran, A., Montironi, R., Hodges, K. B. & Cheng, L., Jul 1 2010, In : American journal of clinical pathology. 134, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Clonal origin of multifocal hepatocellular carcinoma

Hodges, K. B., Cummings, O. W., Saxena, R., Wang, M., Zhang, S., Lopez-Beltran, A., Montironi, R., Nour, H. & Cheng, L., Sep 1 2010, In : Cancer. 116, 17, p. 4078-4085 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Duloxetine hepatotoxicity: A case-series from the drug-induced liver injury network

Vuppalanchi, R., Hayashi, P. H., Chalasani, N., Fontana, R. J., Bonkovsky, H., Saxena, R., Kleiner, D. & Hoofnagle, J. H., Nov 1 2010, In : Alimentary Pharmacology and Therapeutics. 32, 9, p. 1174-1183 10 p.

Research output: Contribution to journalArticle

38 Scopus citations
23 Scopus citations
38 Scopus citations

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease

Bell, L. N., Theodorakis, J. L., Vuppalanchi, R., Saxena, R., Bemis, K. G., Wang, M. & Chalasani, N., Jan 1 2010, In : Hepatology. 51, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

87 Scopus citations
2009

Differential gene expression profiling of esophageal adenocarcinoma

Hammoud, Z. T., Badve, S., Zhao, Q., Li, L., Saxena, R., Thorat, M. A., Morimiya, A., Rieger, K. M. & Kesler, K. A., Apr 1 2009, In : Journal of Thoracic and Cardiovascular Surgery. 137, 4, p. 829-834 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

NF-κB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy

Wu, J. M., Sheng, H., Saxena, R., Skill, N. J., Bhat-Nakshatri, P., Yu, M., Nakshatri, H. & Maluccio, M. A., Jun 18 2009, In : Cancer Letters. 278, 2, p. 145-155 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine

Lee, L., Alloosh, M., Saxena, R., Van Alstine, W., Watkins, B. A., Klaunig, J. E., Sturek, M. & Chalasani, N., Nov 25 2009, In : Hepatology. 50, 1, p. 56-67 12 p.

Research output: Contribution to journalArticle

124 Scopus citations

Pancreatic Steatosis Promotes Dissemination and Lethality of Pancreatic Cancer

Mathur, A., Zyromski, N. J., Pitt, H. A., Al-Azzawi, H., Walker, J. J., Saxena, R. & Lillemoe, K. D., May 1 2009, In : Journal of the American College of Surgeons. 208, 5, p. 989-994 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

Pathologic diagnosis of early hepatocellular carcinoma: A report of the International Consensus Group for Hepatocellular Neoplasia

Kojiro, M., Wanless, I. R., Alves, V., Badve, S., Balabaud, C., Bedosa, P., Bhathal, P., Bioulac-Sage, P., Brunt, E. M., Burt, A. D., Craig, J. R., Dhillon, A., Ferrell, L., Geller, S. A., Goodman, Z. D., Gouw, A. S. H., Guido, M., Guindi, M., Hytiroglou, P., Kage, M. & 15 others, Kondo, F., Kudo, M., Lauwers, G. Y., Nakano, M., Paradis, V., Park, Y. N., Quaglia, A., Roncalli, M., Roskams, T., Ruebner, B., Sakamoto, M., Saxena, R., Theise, N. D., Thung, S. & Taniakos, D., Jan 1 2009, In : Hepatology. 49, 2, p. 658-664 7 p.

Research output: Contribution to journalArticle

502 Scopus citations

Robust hepatic gene silencing for functional studies using helper-dependent adenoviral vectors

Ruiz, R., Witting, S. R., Saxena, R. & Morral, N., Jan 1 2009, In : Human gene therapy. 20, 1, p. 87-94 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Sulindac Prevents Carcinogen-Induced Intrahepatic Cholangiocarcinoma Formation In Vivo

Wentz, S. C., Yip-Schneider, M. T., Gage, E. A., Saxena, R., Badve, S. & Schmidt, C. M., Nov 1 2009, In : Journal of Surgical Research. 157, 1, p. e87-e95

Research output: Contribution to journalArticle

5 Scopus citations

Value of diffusion-weighted MRI for assessing liver fibrosis and cirrhosis

Sandrasegaran, K., Akisik, F. M., Lin, C., Tahir, B., Rajan, J., Saxena, R. & Aisen, A. M., Dec 1 2009, In : American Journal of Roentgenology. 193, 6, p. 1556-1560 5 p.

Research output: Contribution to journalArticle

147 Scopus citations
2008

Helper-dependent adenovirus-mediated short hairpin RNA expression in the liver activates the interferon response

Witting, S. R., Brown, M., Saxena, R., Nabinger, S. & Morral, N., Jan 25 2008, In : Journal of Biological Chemistry. 283, 4, p. 2120-2128 9 p.

Research output: Contribution to journalArticle

29 Scopus citations
2007

A novel biomarker for the detection of esophageal adenocarcinoma

Hammoud, Z. T., Badve, S., Saxena, R., Kesler, K. A., Rieger, K., Malkas, L. H. & Hickey, R. J., Jan 1 2007, In : Journal of Thoracic and Cardiovascular Surgery. 133, 1, p. 82-87 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cholecystosteatosis: An explanation for increased cholecystectomy rates

Al-Azzawi, H. H., Nakeeb, A., Saxena, R., Maluccio, M. A. & Pitt, H. A., Jul 1 2007, In : Journal of Gastrointestinal Surgery. 11, 7, p. 835-843 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Complete reversal of glycogen hepatopathy with pancreas transplantation: Two cases

Fridell, J. A., Saxena, R., Chalasani, N. P., Goggins, W. C., Powelson, J. A. & Cummings, O. W., Jan 1 2007, In : Transplantation. 83, 1, p. 84-86 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Correlation of CT enteroclysis with surgical pathology in Crohn's disease

Chiorean, M. V., Sandrasegaran, K., Saxena, R., Maglinte, D. D., Nakeeb, A. & Johnson, C. S., Nov 1 2007, In : American Journal of Gastroenterology. 102, 11, p. 2541-2550 10 p.

Research output: Contribution to journalArticle

134 Scopus citations

Fatty pancreas: A factor in postoperative pancreatic fistula

Mathur, A., Pitt, H. A., Marine, M., Saxena, R., Schmidt, C. M., Howard, T. J., Nakeeb, A., Zyromski, N. J. & Lillemoe, K. D., Dec 1 2007, In : Annals of surgery. 246, 6, p. 1058-1064 7 p.

Research output: Contribution to journalArticle

195 Scopus citations

Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse: Roles of osteopontin

Shao, J., Washington, M. K., Saxena, R. & Sheng, H., Dec 1 2007, In : Carcinogenesis. 28, 12, p. 2476-2483 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Intravenous interferon during the anhepatic phase of liver retransplantation and prevention of recurrence of cholestatic hepatitis C virus

Kwo, P. Y., Saxena, R., Cummings, O. W. & Tector, A. J., Dec 1 2007, In : Liver Transplantation. 13, 12, p. 1710-1713 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Nonalcoholic fatty pancreas disease

Mathur, A., Marine, M., Lu, D., Swartz-Basile, D. A., Saxena, R., Zyromski, N. J. & Pitt, H. A., Aug 23 2007, In : HPB. 9, 4, p. 312-318 7 p.

Research output: Contribution to journalArticle

113 Scopus citations
48 Scopus citations
2006

Hepatobiliary disease in sarcoidosis

Kahi, C. J., Saxena, R., Temkit, MH., Canlas, K., Roberts, S., Knox, K., Wilkes, D. & Kwo, P. Y., Jun 1 2006, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 23, 2, p. 117-123 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Liver transplantation for liver rupture due to light chain deposition disease: A case report

Croitoru, A. G., Hytiroglou, P., Schwartz, M. E. & Saxena, R., Aug 1 2006, In : Seminars in Liver Disease. 26, 3, p. 298-303 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
27 Scopus citations
2005

A 37-year-old man with a pleural mass

Eichelberger, L., Jones, T. D., Vance, G. & Saxena, R., Aug 1 2005, In : Archives of Pathology and Laboratory Medicine. 129, 8, p. 1063-1064 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

CD117+ small cell lung cancer lacks the asp 816→val point mutation in exon 17

Mojica, W. D., Saxena, R., Starostik, P. & Cheney, R. T., Nov 1 2005, In : Histopathology. 47, 5, p. 517-522 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Lymphangiogenesis does not occur in breast cancer

Agarwal, B., Saxena, R., Morimiya, A., Mehrotra, S. & Badve, S., Nov 1 2005, In : American Journal of Surgical Pathology. 29, 11, p. 1449-1455 7 p.

Research output: Contribution to journalArticle

71 Scopus citations
2004

Hepatocellular proliferation and changes in microarchitecture of right lobe allografts in adult transplant recipients

Huang, R., Schiano, T. D., Amolat, M. J., Miller, C. M., Thung, S. N. & Saxena, R., Dec 1 2004, In : Liver Transplantation. 10, 12, p. 1461-1467 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Hepatocyte nuclear factor-1 alpha inactivation in familial liver adenomatosis

Saxena, R., 2004, In : Laboratory Investigation. 84, 5, p. 533-534 2 p.

Research output: Contribution to journalArticle

Pancreatic duct strictures are a common cause of recurrent pancreatitis after successful management of pancreatic necrosis

Howard, T. J., Moore, S. A., Saxena, R., Matthews, D. E., Schmidt, C. M. & Wiebke, E. A., Oct 2004, In : Surgery. 136, 4, p. 909-916 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

The Canals of Hering Might Represent A Target of Methotrexate Hepatic Toxicity

Hytiroglou, P., Tobias, H., Saxena, R., Abramidou, M., Papadimitriou, C. S. & Theise, N. D., Mar 2004, In : American journal of clinical pathology. 121, 3, p. 324-329 6 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations
2002

Destruction of canals of Hering in primary biliary cirrhosis

Saxena, R., Hytiroglou, P., Thung, S. N. & Theise, N. D., Oct 1 2002, In : Human pathology. 33, 10, p. 983-988 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers

Kotoula, V., Hytiroglou, P., Pyrpasopoulou, A., Saxena, R., Thung, S. N. & Papadimitriou, C. S., Jun 4 2002, In : Liver. 22, 1, p. 57-69 13 p.

Research output: Contribution to journalArticle

45 Scopus citations

Radiation pneumonitis in mice: A severe injury model for pneumocyte engraftment from bone marrow

Theise, N. D., Henegariu, O., Grove, J., Jagirdar, J., Kao, P. N., Crawford, J. M., Badve, S., Saxena, R. & Krause, D. S., Nov 1 2002, In : Experimental Hematology. 30, 11, p. 1333-1338 6 p.

Research output: Contribution to journalArticle

175 Scopus citations

Utilization of acidophil bodies in the diagnosis of recurrent hepatitis c infection after orthotopic liver transplantation

Saxena, R., Crawford, J. M., Navarro, V. J., Friedman, A. L. & Robert, M. E., Sep 2002, In : Modern Pathology. 15, 9, p. 897-903 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Venous invasion may predict lymph node metastasis in early rectal cancer

Bayar, S., Saxena, R., Emir, B. & Salem, R. R., Jun 2002, In : European Journal of Surgical Oncology. 28, 4, p. 413-417 5 p.

Research output: Contribution to journalArticle

35 Scopus citations
2001

A 37-year-old male with hepatomegaly, neurologic and skin involvement associated with elevated urinary porphyrin excretion

Saxena, R., Shetty, K. & Berk, P. D., Apr 5 2001, In : Seminars in Liver Disease. 21, 1, p. 119-128 10 p.

Research output: Contribution to journalArticle

2000

Biliary cystadenocarcinoma with two types of tumour cells

Hytiroglou, P., Zurac, S., Popescu, I., Popovici, D., Tanasescu, C., Saxena, R. & Papadimitriou, C. S., Jan 1 2000, In : Virchows Archiv. 437, 5, p. 555-559 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation

Theise, N. D., Badve, S., Saxena, R., Henegariu, O., Sell, S., Crawford, J. M. & Krause, D. S., Jan 1 2000, In : Hepatology. 31, 1, p. 235-240 6 p.

Research output: Contribution to journalArticle

881 Scopus citations

Expression of p53 and PCNA in cholangiocarcinoma and primary sclerosing cholangitis

Batheja, N., Suriawinata, A., Saxena, R., Ionescu, G., Schwartz, M. & Thung, S. N., Dec 1 2000, In : Modern Pathology. 13, 12, p. 1265-1268 4 p.

Research output: Contribution to journalArticle

40 Scopus citations

Foreign body reaction to a metal clip causing a benign bile duct stricture 16 years after open cholecystectomy: Report of a case

Bayar, S., Saxena, R. & Salem, R. R., Jan 1 2000, In : Surgery Today. 30, 6, p. 534-536 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

HCV RNA levels in hepatocellular carcinomas and adjacent non-tumorous livers

Dash, S., Saxena, R., Myung, J., Rege, T., Tsuji, H., Gaglio, P., Garry, R. F., Thung, S. N. & Gerber, M. A., Oct 1 2000, In : Journal of Virological Methods. 90, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Intraoperative enteroscopy for diagnosis of a bleeding jejunal lymphangioma

Ugwonali, O., Coady, M., Saxena, R., Robert, M., Horowitz, N. & Topazian, M., Dec 12 2000, In : Journal of Clinical Gastroenterology. 31, 4, p. 333-335 3 p.

Research output: Contribution to journalArticle

9 Scopus citations
1999

De novo hepatocellular carcinoma in a hepatic allograft with recurrent hepatitis C cirrhosis

Saxena, R., Ye, M. Q., Emre, S., Klion, F., Nalesnik, M. A. & Thung, S. N., Jan 1 1999, In : Liver Transplantation and Surgery. 5, 1, p. 81-82 2 p.

Research output: Contribution to journalArticle

45 Scopus citations

Gene therapy to promote thromboresistance: Local overexpression of tissue plasminogen activator to prevent arterial thrombosis in an in vivo rabbit model

Waugh, J. M., Kattash, M., Li, J., Yuksel, E., Kuo, M. D., Lussier, M., Weinfeld, A. B., Saxena, R., Rabinovsky, E. D., Thung, S., Woo, S. L. C. & Shenaq, S. M., Feb 2 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 3, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Local overexpression of thrombomodulin for in vivo prevention of arterial thrombosis in a rabbit model

Waugh, J. M., Yuksel, E., Li, J., Kuo, M. D., Kattash, M., Saxena, R., Geske, R., Thung, S. N., Shenaq, S. M. & Wooc, S. L. C., Jan 8 1999, In : Circulation research. 84, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations