Samer Gawrieh

  • 555 Citations
  • 13 h-Index
20022019
If you made any changes in Pure, your changes will be visible here soon.

Publications 2002 2019

2019

Apolipoprotein B and PNPLA3 Double Heterozygosity in a Father–Son Pair With Advanced Nonalcoholic Fatty Liver Disease

Jansson-Knodell, C. L., Gawrieh, S., McIntyre, A. D., Liang, T., Hegele, R. A. & Chalasani, N., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Apolipoproteins B
Nuclear Family
Fathers
Non-alcoholic Fatty Liver Disease
2 Citations (Scopus)

Characteristics, aetiologies and trends of hepatocellular carcinoma in patients without cirrhosis: a United States multicentre study

Gawrieh, S., Dakhoul, L., Miller, E., Scanga, A., deLemos, A., Kettler, C., Burney, H., Liu, H., Abu-Sbeih, H., Chalasani, N. & Wattacheril, J., Jan 1 2019, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Multicenter Studies
Hepatocellular Carcinoma
Fibrosis
Liver Diseases
Hepacivirus

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

and the NASH Clinical Research Network, Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1626-1635 10 p.

Research output: Contribution to journalArticle

Transaminases
Fibrosis
Aspartate Aminotransferases
Alanine Transaminase
Histology

Is Fasting Necessary for Individuals With Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?

Vuppalanchi, R., Weber, R., Russell, S., Gawrieh, S., Samala, N., Slaven, J. E., Harden, L. & Chalasani, N., Jun 1 2019, In : The American journal of gastroenterology. 114, 6, p. 995-997 3 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Vibration
Fasting
Meals
Liver
7 Citations (Scopus)
Metformin
Fatty Liver
Fibrosis
Hepatocellular Carcinoma
Transplants
1 Citation (Scopus)

Older Age and Disease Duration Are Highly Associated with Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis

Dakhoul, L., Jones, K. R., Gawrieh, S., Ghabril, M., McShane, C., Vuppalanchi, R., Vilar-Gomez, E., Nephew, L., Chalasani, N. & Lammert, C., Jan 1 2019, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Autoimmune Hepatitis
Hepatocellular Carcinoma
Fibrosis
Autoimmune Diseases
Medical Records
9 Citations (Scopus)
Vitamin E
Fibrosis
Transplants
Survival
Liver
2018
5 Citations (Scopus)

Autoimmune Hepatitis in the Elderly: Diagnosis and Pharmacologic Management

Rizvi, S. & Gawrieh, S., Jul 4 2018, (Accepted/In press) In : Drugs and Aging. p. 1-14 14 p.

Research output: Contribution to journalArticle

Autoimmune Hepatitis
Prednisone
Steroids
Essential Drugs
Chemical and Drug Induced Liver Injury
1 Citation (Scopus)

Automated assessment of steatosis in murine fatty liver

Sethunath, D., Morusu, S., Tuceryan, M., Cummings, O., Zhang, H., Yin, X-M., Vanderbeck, S., Chalasani, N. & Gawrieh, S., May 1 2018, In : PLoS One. 13, 5, e0197242.

Research output: Contribution to journalArticle

fatty liver
Fatty Liver
Liver
Liver Diseases
liver diseases
11 Citations (Scopus)

Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis

for the NASH CRN, Mar 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 5, p. 645-656 12 p.

Research output: Contribution to journalArticle

Fatty Liver
Weight Loss
Weights and Measures
Placebos
Histology
1 Citation (Scopus)

Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development

Lubecka, K., Flower, K., Beetch, M., Qiu, J., Kurzava, L., Buvala, H., Ruhayel, A., Gawrieh, S., Liangpunsakul, S., Gonzalez, T., McCabe, G., Chalasani, N., Flanagan, J. M. & Stefanska, B., Jan 1 2018, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

DNA Methylation
Hepatocellular Carcinoma
Neoplasms
Nucleic Acid Regulatory Sequences
Delayed Diagnosis
3 Citations (Scopus)

Lower expression of tumor microRNA-26a is associated with higher recurrence in patients with hepatocellular carcinoma undergoing surgical treatment

Jones, K. R., Nabinger, S. C., Lee, S., Sahu, S. S., Althouse, S., Saxena, R., Johnson, M. S., Chalasani, N., Gawrieh, S. & Kota, J., Jan 1 2018, (Accepted/In press) In : Journal of Surgical Oncology.

Research output: Contribution to journalArticle

MicroRNAs
Hepatocellular Carcinoma
Recurrence
Neoplasms
Liver Diseases
8 Citations (Scopus)

Primate fetal hepatic responses to maternal obesity: Epigenetic signalling pathways and lipid accumulation

Puppala, S., Li, C., Glenn, J. P., Saxena, R., Gawrieh, S., Quinn, A., Palarczyk, J., Dick, E. J., Nathanielsz, P. W. & Cox, L. A., Jan 1 2018, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journalArticle

Epigenomics
Primates
Obesity
Mothers
Lipids
6 Citations (Scopus)

Proteomic characterization of high-density lipoprotein particles in patients with non-alcoholic fatty liver disease

Rao, P. K., Merath, K., Drigalenko, E., Jadhav, A. Y. L., Komorowski, R. A., Goldblatt, M. I., Rohatgi, A., Sarzynski, M. A., Gawrieh, S. & Olivier, M., Mar 6 2018, In : Clinical Proteomics. 15, 1, 10.

Research output: Contribution to journalArticle

HDL Lipoproteins
Liver
Proteomics
Proteome
Fatty Liver
2017
10 Citations (Scopus)
Cysteamine
Phase II Clinical Trials
Unsaturated Fatty Acids
Histology
Randomized Controlled Trials
8 Citations (Scopus)

Function of inhibitor of Bruton's tyrosine kinase isoform α(IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response

Willy, J. A., Young, S. K., Mosley, A., Gawrieh, S., Stevens, J. L., Masuoka, H. & Wek, R., Aug 25 2017, In : Journal of Biological Chemistry. 292, 34, p. 14050-14065 16 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Autophagy
Protein Isoforms
Proteins
Endoplasmic Reticulum
13 Citations (Scopus)

Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis

Yang, J. D., Abdelmalek, M. F., Guy, C. D., Gill, R. M., Lavine, J. E., Yates, K., Klair, J., Terrault, N. A., Clark, J. M., Unalp-Arida, A., Diehl, A. M., Suzuki, A., Dasarathy, S., Dasarathy, J., Hawkins, C., McCullough, A. J., Dasarathy, S., McCullough, A. J., Pagadala, M., Pai, R. & 89 others, Sargent, R., Abdelmalek, M. F., Bashir, M., Buie, S., Diehl, A. M., Guy, C., Kigongo, C., Pan, Y. P., Piercy, D., Chalasani, N., Cummings, O. W., Gawrieh, S., Ghabril, M., Marri, S., Ragozzino, L., Sandrasegaran, K., Vuppalanchi, R., King, D., Osmack, P., Siegner, J., Stewart, S., Neuschwander-Tetri, B. A., Torretta, S., Ang, B., Behling, C., Bhatt, A., Loomba, R., Middleton, M., Patton, H., Sirlin, C., Aouizerat, B., Bass, N. M., Brandman, D., Ferrell, L. D., Gill, R., Hameed, B., Ramos, C., Terrault, N., Ungermann, A., Atla, P., Croft, B., Garcia, R., Garcia, S., Sheikh, M., Singh, M., Boyett, S., Carucci, L., Contos, M. J., Kraft, K., Luketic, V. A. C., Puri, P., Sanyal, A. J., Schlosser, J., Siddiqui, M. S., Wolford, B., Ackermann, S., Cooney, S., Coy, D., Gelinas, K., Kowdley, K. V., Lee, M., Pierce, T., Mooney, J., Nelson, J. E., Shaw, C., Siddique, A., Wang, C., Brunt, E. M., Fowler, K., Kleiner, D. E., Grave, G. D., Doo, E. C., Hoofnagle, J. H., Robuck, P. R., Sherker, A., Belt, P., Clark, J. M., Donithan, M., Hallinan, E., Isaacson, M., May, K. P., Miriel, L., Sternberg, A., Tonascia, J., Ünalp-Arida, A., Van Natta, M., Vaughn, I., Wilson, L. & Yates, K., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 127-131.e2

Research output: Contribution to journalArticle

Mallory Bodies
Hormones
Inflammation
Physiological Stress
Hepatocytes
5 Citations (Scopus)

Risk factors for hepatocellular carcinoma in cirrhosis due to nonalcoholic fatty liver disease: A multicenter, case-control study

Corey, K. E., Gawrieh, S., deLemos, A. S., Zheng, H., Scanga, A. E., Haglund, J. W., Sanchez, J., Danford, C. J., Comerford, M., Bossi, K., Munir, S., Chalasani, N. & Wattacheril, J., 2017, In : World Journal of Hepatology. 9, 7, p. 385-390 6 p.

Research output: Contribution to journalArticle

Case-Control Studies
Hepatocellular Carcinoma
Fibrosis
Transplants
Non-alcoholic Fatty Liver Disease

Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans

FLIP Investigators & FLPGP Investigators, 2017, In : Aging. 9, 1, p. 26-40 15 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Alleles
Haplotypes
Liver
Electrophoretic Mobility Shift Assay
2016
5 Citations (Scopus)

Management of Difficult Cases of Autoimmune Hepatitis

Lammert, C., Loy, V. M., Oshima, K. & Gawrieh, S., Feb 1 2016, In : Current Gastroenterology Reports. 18, 2, p. 9 1 p.

Research output: Contribution to journalReview article

Autoimmune Hepatitis
Case Management
Liver
Liver Failure
Azathioprine
2015
5 Citations (Scopus)

Automatic quantification of lobular inflammation and hepatocyte ballooning in nonalcoholic fatty liver disease liver biopsies

Vanderbeck, S., Bockhorst, J., Kleiner, D., Komorowski, R., Chalasani, N. & Gawrieh, S., May 1 2015, In : Human Pathology. 46, 5, p. 767-775 9 p.

Research output: Contribution to journalArticle

Hepatocytes
Inflammation
Biopsy
Liver
Hematoxylin

Current and emerging therapies for nonalcoholic fatty liver disease

Gawrieh, S. & Chalasani, N., Jan 1 2015, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside. Springer International Publishing, p. 313-337 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Therapeutics
pioglitazone
Hepatocellular Carcinoma
Fibrosis
Non-alcoholic Fatty Liver Disease
21 Citations (Scopus)

Pharmacotherapy for Nonalcoholic Fatty Liver Disease

Gawrieh, S. & Chalasani, N., Aug 20 2015, In : Seminars in Liver Disease. 35, 3, p. 338-348 11 p.

Research output: Contribution to journalArticle

Drug Therapy
pioglitazone
Ursodeoxycholic Acid
Pentoxifylline
End Stage Liver Disease
2 Citations (Scopus)
Sex Hormone-Binding Globulin
Gonadal Steroid Hormones
Fatty Liver
Fats
Liver
2014
2 Citations (Scopus)

A case study: Refractory recurrent autoimmune hepatitis following liver transplantation in two male patients

Tencate, V., Komorowski, R., Cronin, D., Hong, J. & Gawrieh, S., Jan 2014, In : Transplantation Proceedings. 46, 1, p. 298-300 3 p.

Research output: Contribution to journalArticle

Autoimmune Hepatitis
Liver Transplantation
Transplantation
Transplants
Survival
15 Citations (Scopus)

Automatic classification of white regions in liver biopsies by supervised machine learning

Vanderbeck, S., Bockhorst, J., Komorowski, R., Kleiner, D. E. & Gawrieh, S., 2014, In : Human Pathology. 45, 4, p. 785-792 8 p.

Research output: Contribution to journalArticle

Biopsy
Portal Vein
Liver
Hematoxylin
Eosine Yellowish-(YS)
2013
23 Citations (Scopus)

High prevalence of vitamin A deficiency and vitamin D deficiency in patients evaluated for liver transplantation

Venu, M., Martin, E., Saeian, K. & Gawrieh, S., Jun 2013, In : Liver Transplantation. 19, 6, p. 627-633 7 p.

Research output: Contribution to journalArticle

Vitamin A Deficiency
Vitamin D Deficiency
Liver Transplantation
Night Blindness
Liver Diseases
20 Citations (Scopus)

Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity

Guichelaar, M. M. J., Gawrieh, S., Olivier, M., Viker, K., Krishnan, A., Sanderson, S., Malinchoc, M., Watt, K. D., Swain, J. M., Sarr, M. & Charlton, M. R., Sep 2013, In : Obesity. 21, 9, p. 1935-1941 7 p.

Research output: Contribution to journalArticle

Morbid Obesity
Obesity
Liver
Bariatric Surgery
Phospholipases
9 Citations (Scopus)

NAFLD fibrosis score: Is it ready for wider use in clinical practice and for clinical trials?

Gawrieh, S. & Chalasani, N., Oct 2013, In : Gastroenterology. 145, 4, p. 717-719 3 p.

Research output: Contribution to journalArticle

Fatty Liver
Fibrosis
Clinical Trials
Non-alcoholic Fatty Liver Disease
2 Citations (Scopus)

Swallow syncope

Gawrieh, S., Jan 1 2013, Principles of Deglutition: A Multidisciplinary Text for Swallowing and its Disorders. Springer New York, p. 445-448 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Syncope
Deglutition
Esophageal Diseases
Cardiac Arrhythmias
Swallows
2012
27 Citations (Scopus)

Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD

Gawrieh, S., Marion, M. C., Komorowski, R., Wallace, J., Charlton, M., Kissebah, A., Langefeld, C. D. & Olivier, M., Apr 2012, In : Digestive Diseases and Sciences. 57, 4, p. 952-957 6 p.

Research output: Contribution to journalArticle

PPAR gamma
Haplotypes
Peroxisome Proliferators
Genes
Alleles
2011
39 Citations (Scopus)

Effects of interventions on intra- and interobserver agreement on interpretation of nonalcoholic fatty liver disease histology

Gawrieh, S., Knoedler, D. M., Saeian, K., Wallace, J. R. & Komorowski, R. A., Feb 2011, In : Annals of Diagnostic Pathology. 15, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

Histology
Inflammation
Non-alcoholic Fatty Liver Disease
Fibrosis
Phenotype
2010
34 Citations (Scopus)

A noninvasive clinical scoring model predicts risk of nonalcoholic steatohepatitis in morbidly obese patients

Ulitsky, A., Ananthakrishnan, A. N., Komorowski, R., Wallace, J., Surapaneni, S. N., Franco, J., Saeian, K. & Gawrieh, S., Jun 2010, In : Obesity Surgery. 20, 6, p. 685-691 7 p.

Research output: Contribution to journalArticle

Liver
Biopsy
Bariatric Surgery
Hypertriglyceridemia
Sleep Apnea Syndromes
24 Citations (Scopus)

Hepatic gene networks in morbidly obese patients with nonalcoholic fatty liver disease

Gawrieh, S., Baye, T. M., Carless, M., Wallace, J., Komorowski, R., Kleiner, D. E., Andris, D., Makladi, B., Cole, R., Charlton, M., Curran, J., Dyer, T. D., Charlesworth, J., Wilke, R., Blangero, J., Kissebah, A. H. & Olivier, M., Dec 2010, In : Obesity Surgery. 20, 12, p. 1698-1709 12 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Liver
Multigene Family
Genes
Non-alcoholic Fatty Liver Disease
23 Citations (Scopus)

INSIG1 infl uences obesity-related hypertriglyceridemia in humans

Smith, E. M., Zhang, Y., Baye, T. M., Gawrieh, S., Cole, R., Blangero, J., Carless, M. A., Curran, J. E., Dyer, T. D., Abraham, L. J., Moses, E. K., Kissebah, A. H., Martin, L. J. & Olivier, M., Apr 1 2010, In : Journal of Lipid Research. 51, 4, p. 701-708 8 p.

Research output: Contribution to journalArticle

Hypertriglyceridemia
Triglycerides
Obesity
Genes
Quantitative Trait Loci
2008
71 Citations (Scopus)

Low circulating levels of dehydroepiandrosterone in histologically advanced nonalcoholic fatty liver disease

Charlton, M., Angulo, P., Chalasani, N., Merriman, R., Viker, K., Charatcharoenwitthaya, P., Sanderson, S., Gawrieh, S., Krishnan, A. & Lindor, K., Feb 2008, In : Hepatology. 47, 2, p. 484-492 9 p.

Research output: Contribution to journalArticle

Dehydroepiandrosterone
Fibrosis
Non-alcoholic Fatty Liver Disease
Liver Diseases
PPAR alpha
2005
62 Citations (Scopus)

Early hepatic stellate cell activation predicts severe hepatitis C recurrence after liver transplantation

Gawrieh, S., Papouchado, B. G., Burgart, L. J., Kobayashi, S., Charlton, M. R. & Gores, G. J., Oct 2005, In : Liver Transplantation. 11, 10, p. 1207-1213 7 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Hepatitis C
Liver Transplantation
Recurrence
Fibrosis
10 Citations (Scopus)

Swallow syncope in association with Schatzki ring and hypertensive esophageal peristalsis: Report of three cases and review of the literature

Gawrieh, S., Carroll, T., Hogan, W. J., Soergel, K. H. & Shaker, R., Oct 2005, In : Dysphagia. 20, 4, p. 273-277 5 p.

Research output: Contribution to journalArticle

Peristalsis
Syncope
Deglutition
Esophageal Motility Disorders
Cardiac Arrhythmias
1 Citation (Scopus)

Treatment of actively bleeding Mallory-Weiss syndrome: epinephrine injection or band ligation?

Gawrieh, S. & Shaker, R., Jun 2005, In : Current Gastroenterology Reports. 7, 3, p. 175 1 p.

Research output: Contribution to journalArticle

Mallory-Weiss Syndrome
Single-Blind Method
Gastrointestinal Hemorrhage
Vasoconstrictor Agents
Epinephrine
2 Citations (Scopus)

Variceal band ligation versus propranolol for primary prophylaxis of variceal bleeding in cirrhosis.

Gawrieh, S. & Shaker, R., Jun 2005, In : Current Gastroenterology Reports. 7, 3, p. 175-176 2 p.

Research output: Contribution to journalArticle

Adrenergic beta-Antagonists
Gastrointestinal Hemorrhage
Esophageal and Gastric Varices
Propranolol
Liver Cirrhosis
2004
2 Citations (Scopus)
Esophageal and Gastric Varices
Portal Hypertension
Secondary Prevention
Ligation
Fibrosis
34 Citations (Scopus)

Oxidative stress in nonalcoholic fatty liver disease: Pathogenesis and antioxidant therapies

Gawrieh, S., Opara, E. C. & Koch, T. R., 2004, In : Journal of Investigative Medicine. 52, 8, p. 506-514 9 p.

Research output: Contribution to journalReview article

Oxidative stress
Liver
Oxidative Stress
Antioxidants
Fatty Liver
2003
1 Citation (Scopus)

Effect of Ursodeoxycholic acid on methionine adenosyltransferase activity and hepatic glutathione metabolism in rats

Gawrieh, S. & Koch, T. R., Apr 1 2003, In : American Journal of Gastroenterology. 98, 4, p. 934-935 2 p.

Research output: Contribution to journalComment/debate

Methionine Adenosyltransferase
Ursodeoxycholic Acid
Glutathione
Liver
6 Citations (Scopus)

Medical management of nocturnal symptoms of gastro-oesophageal reflux disease in the elderly

Gawrieh, S. & Shaker, R., 2003, In : Drugs and Aging. 20, 7, p. 509-516 8 p.

Research output: Contribution to journalReview article

Esophageal Diseases
Gastroesophageal Reflux
Esophagitis
Quality of Life
Histamine H2 Antagonists
16 Citations (Scopus)

Neutralizing antibodies in hepatitis C virus infection: A review of immunological and clinical characteristics

Kaplan, M., Gawrieh, S., Cotler, S. J. & Jensen, D. M., Aug 1 2003, In : Gastroenterology. 125, 2, p. 597-604 8 p.

Research output: Contribution to journalReview article

Virus Diseases
Neutralizing Antibodies
Hepacivirus
Hepatitis C
Humoral Immunity
2002
5 Citations (Scopus)

Peripheral mechanisms affecting the lower esophageal sphincter tone

Gawrieh, S. & Shaker, R., Dec 2002, In : Gastroenterology Clinics of North America. 31, 4 SUPPL.

Research output: Contribution to journalReview article

Lower Esophageal Sphincter
Reflex
Stomach
Upper Gastrointestinal Tract
Larynx
4 Citations (Scopus)

Scalp metastases as the first manifestation of pancreatic cancer

Gawrieh, S., Massey, B. T. & Komorowski, R. A., 2002, In : Digestive Diseases and Sciences. 47, 7, p. 1469-1471 3 p.

Research output: Contribution to journalLetter

Mucinous Adenocarcinoma
Fatal Outcome
Skin Neoplasms
Liver Neoplasms
Head and Neck Neoplasms