Samir Gupta

  • 2500 Citations
  • 23 h-Index
1976 …2020

Research output per year

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Publications

  • 2500 Citations
  • 23 h-Index
  • 67 Article
  • 11 Letter
  • 5 Review article
  • 3 Comment/debate
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Article
2020

Elevated cardiac risk score by Atherosclerotic Cardiovascular Disease calculation is associated with albuminuria in older people living with HIV

Johnston, C. D., Ifeagwu, K. C. C., Siegler, E. L., Derry, H., Burchett, C. O., Rice, M. C., Gupta, S. K., Choi, M. E. & Glesby, M. J., May 1 2020, In : AIDS (London, England). 34, 6, p. 947-949 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On-Demand HIV Preexposure Prophylaxis

Liu, S. N., Gufford, B. T., Lu, J. B. L., Bushman, L. R., Anderson, P. L., Bergstrom, R. F., Desta, Z. & Gupta, S. K., May 1 2020, In : Clinical Pharmacology and Therapeutics. 107, 5, p. 1200-1208 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Depression and all-cause mortality risk in HIV-infected and HIV-uninfected US veterans: a cohort study

So-Armah, K., Gupta, S. K., Kundu, S., Stewart, J. C., Goulet, J. L., Butt, A. A., Sico, J. J., Marconi, V. C., Crystal, S., Rodriguez-Barradas, M. C., Budoff, M., Gibert, C. L., Chang, C. C. H., Bedimo, R. & Freiberg, M. S., May 2019, In : HIV Medicine. 20, 5, p. 317-329 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Endothelial colony-forming cell function is reduced during HIV infection

Gupta, S. K., Liu, Z., Sims, E. C., Repass, M. J., Haneline, L. S. & Yoder, M. C., Jan 1 2019, In : Journal of Infectious Diseases. 219, 7, p. 1076-1083 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

GCH1 haplotypes and cardiovascular risk in HIV

Slaven, J. E., Haas, D. W., Liu, Z., Stein, J. H., Brown, T. T. & Gupta, S. K., Aug 1 2019, In : AIDS. 33, 10, p. 1669-1671 3 p.

Research output: Contribution to journalArticle

HIV-Nef protein transfer to endothelial cells requires Rac1 activation and leads to endothelial dysfunction: Implications for statin treatment in HIV patients

Chelvanambi, S., Gupta, S. K., Chen, X., Ellis, B. W., Maier, B. F., Colbert, T. M., Kuriakose, J., Zorlutuna, P., Jolicoeur, P., Obukhov, A. G. & Clauss, M., Oct 11 2019, In : Circulation research. 125, 9, p. 805-820 16 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data from the Veterans Aging Cohort Study

Polanka, B. M., Kundu, S., So-Armah, K. A., Freiberg, M. S., Gupta, S. K., Bedimo, R. J., Budoff, M. J., Butt, A. A., Chang, C. C. H., Gottlieb, S. S., Marconi, V. C., Womack, J. A. & Stewart, J. C., May 1 2019, In : Journal of Acquired Immune Deficiency Syndromes. 81, 1, p. 110-117 8 p.

Research output: Contribution to journalArticle

Renal safety of tenofovir alafenamide vs. tenofovir disoproxil fumarate: A pooled analysis of 26 clinical trials

Gupta, S. K., Post, F. A., Arribas, J. R., Eron, J. J., Wohl, D. A., Clarke, A. E., Sax, P. E., Stellbrink, H. J., Esser, S., Pozniak, A. L., Podzamczer, D., Waters, L., Orkin, C., Rockstroh, J. K., Mudrikova, T., Negredo, E., Elion, R. A., Guo, S., Zhong, L., Carter, C. & 4 others, Martin, H., Brainard, D., Sengupta, D. & Das, M., Jul 15 2019, In : AIDS. 33, 9, p. 1455-1465 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2018

Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function

Sims, E. K., Park, G., Mather, K., Mirmira, R., Liu, Z. & Gupta, S., May 1 2018, In : PLoS One. 13, 5, e0197080.

Research output: Contribution to journalArticle

1 Scopus citations

Long-Term kidney function, proteinuria, and associated risks among HIV-infected and uninfected men

Palella, F. J., Li, X., Gupta, S. K., Estrella, M. M., Phair, J. P., Margolick, J. B., Detels, R., Kingsley, L. & Jacobson, L. P., Jun 19 2018, In : AIDS. 32, 10, p. 1247-1256 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Women have enhanced bone loss associated with phosphaturia and CD4+ cell restoration during initial antiretroviral therapy

ACTG A5224s, A5303 Teams, Nov 13 2018, In : AIDS (London, England). 32, 17, p. 2517-2524 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

BCL6 represses antiviral resistance in follicular T helper cells

Amet, T., Son, Y. M., Jiang, L., Cheon, I. S., Huang, S., Gupta, S. K., Dent, A. L., Montaner, L. J., Yu, Q. & Sun, J., Aug 2017, In : Journal of Leukocyte Biology. 102, 2, p. 527-536 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Bone mineral density reductions after tenofovir disoproxil fumarate initiation and changes in phosphaturia: A secondary analysis of ACTG A5224s

Gupta, S. K., Yeh, E., Kitch, D. W., Brown, T. T., Venuto, C. S., Morse, G. D., Ha, B., Melbourne, K. & McComsey, G. A., Jul 1 2017, In : Journal of Antimicrobial Chemotherapy. 72, 7, p. 2042-2048 7 p., dkx076.

Research output: Contribution to journalArticle

4 Scopus citations

HIV infection, antiretroviral therapy, and measures of endothelial function, inflammation, metabolism, and oxidative stress

Dysangco, A., Liu, Z., Stein, J. H., Dubé, M. P. & Gupta, S. K., Aug 2017, In : PloS one. 12, 8, e0183511.

Research output: Contribution to journalArticle

7 Scopus citations

MMPs/TIMPs imbalances in the peripheral blood and cerebrospinal fluid are associated with the pathogenesis of HIV-1-associated neurocognitive disorders

Xing, Y., Shepherd, N., Lan, J., Li, W., Rane, S., Gupta, S. K., Zhang, S., Dong, J. & Yu, Q., Oct 2017, In : Brain, Behavior, and Immunity. 65, p. 161-172 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
2016

Association Between Depressive Disorders and Incident Acute Myocardial Infarction in Human Immunodeficiency Virus-Infected Adults: Veterans Aging Cohort Study

Khambaty, T., Stewart, J. C., Gupta, S. K., Chang, C. C. H., Bedimo, R. J., Budoff, M. J., Butt, A. A., Crane, H., Gibert, C. L., Leaf, D. A., Rimland, D., Tindle, H. A., So-Armah, K. A., Justice, A. C. & Freiberg, M. S., Nov 1 2016, In : JAMA cardiology. 1, 8, p. 929-937 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Efficacy, safety, bone and metabolic effects of HIV nucleoside reverse transcriptase inhibitor BMS-986001 (AI467003): A phase 2b randomised, controlled, partly blinded trial

Gupta, S. K., McComsey, G. A., Lombaard, J., Echevarría, J., Orrell, C., Avihingsanon, A., Osiyemi, O., Santoscoy, M., Ray, N., Stock, D. A., Joshi, S. R., Hanna, G. J. & Lataillade, M., Jan 1 2016, In : The Lancet HIV. 3, 1, p. e13-e22

Research output: Contribution to journalArticle

6 Scopus citations
121 Scopus citations
2015

A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome

Dahlin, A., Wittwer, M., De La Cruz, M., Woo, J. M., Bam, R., Scharen-Guivel, V., Flaherty, J., Ray, A. S., Cihlar, T., Gupta, S. K. & Giacomini, K. M., Feb 13 2015, In : Pharmacogenetics and Genomics. 25, 2, p. 82-92 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

A randomized, controlled trial of the effect of rilpivirine versus efavirenz on cardiovascular risk in healthy volunteers

Gupta, S., Slaven, J. E., Kamendulis, L. M. & Liu, Z., Oct 1 2015, In : Journal of Antimicrobial Chemotherapy. 70, 10, p. 2889-2893 5 p., dkv195.

Research output: Contribution to journalArticle

5 Scopus citations
1 Scopus citations

Blockage of CD59 function restores activities of neutralizing and nonneutralizing antibodies in triggering antibody-dependent complement-mediated lysis of HIV-1 virions and provirus-activated latently infected cells

Yang, K., Lan, J., Shepherd, N., Hu, N., Xing, Y., Byrd, D., Amet, T., Jewell, C., Gupta, S., Kounga, C., Gao, J. & Yu, Q., 2015, In : Journal of virology. 89, 18, p. 9393-9406 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Brief report: Endothelial colony-forming cells and inflammatory monocytes in HIV

Hays, T. R., Mund, J. A., Liu, Z., Case, J., Ingram, D. A. & Gupta, S. K., Apr 15 2015, In : Journal of Acquired Immune Deficiency Syndromes. 68, 5, p. 550-553 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Depression and human immunodeficiency virus infection are risk factors for incident heart failure among veterans veterans aging cohort study

White, J. R., Chang, C. C. H., So-Armah, K. A., Stewart, J. C., Gupta, S. K., Butt, A. A., Gibert, C. L., Rimland, D., Rodriguez-Barradas, M. C., Leaf, D. A., Bedimo, R. J., Gottdiener, J. S., Kop, W. J., Gottlieb, S. S., Budoff, M. J., Khambaty, T., Tindle, H. A., Justice, A. C. & Freiberg, M. S., Oct 27 2015, In : Circulation. 132, 17, p. 1630-1638 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Intracellular Nef detected in peripheral blood mononuclear cells from HIV patients

Wang, T., Green, L. A., Gupta, S. K., Amet, T., Byrd, D. J., Yu, Q., Twigg, H. L. & Clauss, M., Feb 1 2015, In : AIDS Research and Human Retroviruses. 31, 2, p. 217-220 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Markers of renal disease and function are associated with systemic inflammation in HIV infection

AIDS Clinical Trials Group Study A5224s Team, Nov 2015, In : HIV Medicine. 16, 10, p. 591-598 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reductions in plasma cystatin c after initiation of antiretroviral therapy are associated with reductions in inflammation: ACTG A5224s

Longenecker, C. T., Kitch, D., Sax, P. E., Daar, E. S., Tierney, C., Gupta, S. K. & McComsey, G. A., Jun 1 2015, In : Journal of Acquired Immune Deficiency Syndromes. 69, 2, p. 168-177 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Relationships between renal parameters and serum and urine markers of inflammation in those with and without HIV infection

Shinha, T., Mi, D., Liu, Z., Orschell, C. M., Lederman, M. M. & Gupta, S. K., Apr 1 2015, In : AIDS Research and Human Retroviruses. 31, 4, p. 375-383 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Changes in proteinuria and albuminuria with initiation of antiretroviral therapy: Data from a randomized trial comparing tenofovir disoproxil fumarate/emtricitabine versus abacavir/lamivudine

Wyatt, C. M., Kitch, D., Gupta, S. K., Tierney, C., Daar, E. S., Sax, P. E., Ha, B., Melbourne, K. & McComsey, G. A., Sep 1 2014, In : Journal of Acquired Immune Deficiency Syndromes. 67, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cystatin C-based renal function changes after antiretroviral initiation: A substudy of a randomized trial

Gupta, S. K., Kitch, D., Tierney, C., Daar, E. S., Sax, P. E., Melbourne, K., Ha, B. & McComsey, G. A., 2014, In : Open Forum Infectious Diseases. 1, 1

Research output: Contribution to journalArticle

8 Scopus citations

Fanconi syndrome accompanied by renal function decline with tenofovir disoproxil fumarate: A prospective, case-control study of predictors and resolution in HIV-infected patients

Gupta, S. K., Anderson, A. M., Ebrahimi, R., Fralich, T., Graham, H., Scharen-Guivel, V., Flaherty, J. F., Fortin, C., Kalayjian, R. C., Rachlis, A. & Wyatt, C. M., Mar 20 2014, In : PLoS ONE. 9, 3, e92717.

Research output: Contribution to journalArticle

30 Scopus citations

HIV-1 coinfection profoundly alters intrahepatic chemokine but not inflammatory cytokine profiles in HCV-infected subjects

Hu, S., Ghabril, M., Amet, T., Hu, N., Byrd, D., Yang, K., Vuppalanchi, R., Saxena, R., Desai, M., Lan, J., Johnson, R., Gupta, S., Chalasani, N. & Yu, Q., Feb 6 2014, In : PLoS ONE. 9, 2, e86964.

Research output: Contribution to journalArticle

4 Scopus citations
22 Scopus citations

Microbial translocation and metabolic and body composition measures in treated and untreated HIV infection

Timmons, T., Shen, C., Aldrovandi, G., Rollie, A., Gupta, S. K., Stein, J. H. & Dubé, M. P., Mar 1 2014, In : AIDS Research and Human Retroviruses. 30, 3, p. 272-277 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Plasma apolipoprotein L1 levels do not correlate with CKD

Bruggeman, L. A., O'Toole, J. F., Ross, M. D., Madhavan, S. M., Smurzynski, M., Wu, K., Bosch, R. J., Gupta, S., Pollak, M. R., Sedor, J. R. & Kalayjian, R. C., Mar 1 2014, In : Journal of the American Society of Nephrology. 25, 3, p. 634-644 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells

Lan, J., Yang, K., Byrd, D., Hu, N., Amet, T., Shepherd, N., Desai, M., Gao, J., Gupta, S., Sun, Y. & Yu, Q., Oct 1 2014, In : Journal of Immunology. 193, 7, p. 3577-3589 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Substantial effect of efavirenz monotherapy on bilirubin levels in healthy volunteers

Metzger, I. F., Quigg, T. C., Epstein, N., Aregbe, A. O., Thong, N., Callaghan, J. T., Flockhart, D. A., Nguyen, A. T., Stevens, C. K., Gupta, S. K. & Desta, Z., Dec 1 2014, In : Current Therapeutic Research - Clinical and Experimental. 76, p. 64-69 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction

Wang, T., Green, L. A., Gupta, S. K., Kim, C., Wang, L., Almodovar, S., Flores, S. C., Prudovsky, I. A., Jolicoeur, P., Liu, Z. & Clauss, M., Mar 7 2014, In : PloS one. 9, 3, e91063.

Research output: Contribution to journalArticle

33 Scopus citations
2013
33 Scopus citations

Pentoxifylline, Inflammation, and Endothelial Function in HIV-Infected Persons: A Randomized, Placebo-Controlled Trial

Gupta, S. K., Mi, D., Dubé, M. P., Saha, C. K., Johnson, R. M., Stein, J. H., Clauss, M. A., Mather, K. J., Desta, Z. & Liu, Z., Apr 9 2013, In : PloS one. 8, 4, e60852.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Metabolic effects of darunavir/ritonavir versus atazanavir/ritonavir in treatment-naive, HIV Type 1-infected subjects over 48 weeks

Aberg, J. A., Tebas, P., Overton, E. T., Gupta, S. K., Sax, P. E., Landay, A., Falcon, R., Ryan, R. & De La Rosa, G., Oct 1 2012, In : AIDS Research and Human Retroviruses. 28, 10, p. 1184-1195 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Relationship between Microbial Translocation and Endothelial Function in HIV Infected Patients

Blodget, E., Shen, C., Aldrovandi, G., Rollie, A., Gupta, S. K., Stein, J. H. & Dubé, M. P., Aug 30 2012, In : PloS one. 7, 8, e42624.

Research output: Contribution to journalArticle

27 Scopus citations

Worsening Endothelial Function with Efavirenz Compared to Protease Inhibitors: A 12-Month Prospective Study

Gupta, S. K., Shen, C., Moe, S. M., Kamendulis, L. M., Goldman, M. & Dubé, M. P., Sep 20 2012, In : PloS one. 7, 9, e45716.

Research output: Contribution to journalArticle

37 Scopus citations
2011

Abacavir, didanosine and tenofovir do not induce inflammatory, apoptotic or oxidative stress genes in coronary endothelial cells

Kim, C., Gupta, S. K., Green, L., Taylor, B. M., Deuter-Reinhard, M., Desta, Z. & Clauss, M., 2011, In : Antiviral Therapy. 16, 8, p. 1335-1339 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
3 Scopus citations

Neither proteinuria nor albuminuria is associated with endothelial dysfunction in HIV-infected patients without diabetes or hypertension

Gupta, S. K., Shen, C., Mather, K. J., Agarwal, R. & Dubé, M. P., Dec 15 2011, In : Journal of Infectious Diseases. 204, 12, p. 1946-1950 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
10 Scopus citations
2010

Anti-inflammatory treatment with pentoxifylline improves HIV-related endothelial dysfunction: A pilot study

Gupta, S. K., Johnson, R. M., Mather, K. J., Clauss, M., Rehman, J., Saha, C., Desta, Z. & Dubé, M. P., Jun 1 2010, In : AIDS. 24, 9, p. 1377-1380 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206

Tungsiripat, M., Kitch, D., Glesby, M. J., Gupta, S. K., Mellors, J. W., Moran, L., Jones, L., Alston-Smith, B., Rooney, J. F. & Aberg, J. A., Jul 17 2010, In : AIDS. 24, 11, p. 1781-1784 4 p.

Research output: Contribution to journalArticle

65 Scopus citations