Sean O'Connor

  • 5547 Citations
  • 44 h-Index
1984 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

  • 5547 Citations
  • 44 h-Index
  • 114 Article
  • 7 Conference contribution
  • 4 Review article
2020

To Infuse or Ingest in Human Laboratory Alcohol Research

Cyders, M. A., Plawecki, M. H., Corbin, W., King, A., McCarthy, D. M., Ramchandani, V. A., Weafer, J. & O'Connor, S. J., Apr 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 4, p. 764-776 13 p.

Research output: Contribution to journalReview article

2019

Comparison of Subjective Responses to Oral and Intravenous Alcohol Administration Under Similar Systemic Exposures

Plawecki, M. H., Durrani, A. M., Boes, J., Wetherill, L., Kosobud, A., O'Connor, S. & Ramchandani, V. A., Apr 2019, In : Alcoholism: Clinical and Experimental Research. 43, 4, p. 597-606 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Alcohol affects the P3 component of an adaptive stop signal task ERP

Plawecki, M. H., Windisch, K. A., Wetherill, L., Kosobud, A. E. K., Dzemidzic, M., Kareken, D. A. & O'Connor, S. J., Aug 2018, In : Alcohol. 70, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alcohol intoxication progressively impairs drivers' capacity to detect important environmental stimuli

Plawecki, M. H., Koskie, S., Kosobud, A., Justiss, M. D. & O'Connor, S., Dec 2018, In : Pharmacology Biochemistry and Behavior. 175, p. 62-68 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Pairing neutral cues with alcohol intoxication: new findings in executive and attention networks

Oberlin, B. G., Dzemidzic, M., Eiler, W. J. A., Carron, C. R., Soeurt, C. M., Plawecki, M. H., Grahame, N. J., O’Connor, S. J. & Kareken, D. A., Sep 1 2018, In : Psychopharmacology. 235, 9, p. 2725-2737 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sex Differences in Motivation to Self-Administer Alcohol After 2 Weeks of Abstinence in Young-Adult Heavy Drinkers

Plawecki, M. H., White, K., Kosobud, A. E. K., Grahame, N., Zimmermann, U. S., Crabb, D. & O'Connor, S., Oct 2018, In : Alcoholism: Clinical and Experimental Research. 42, 10, p. 1897-1908 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Stress vulnerability and alcohol use and consequences: From human laboratory studies to clinical outcomes

Ramchandani, V. A., Stangl, B. L., Blaine, S. K., Plawecki, M. H., Schwandt, M. L., Kwako, L. E., Sinha, R., Cyders, M. A., O'Connor, S. & Zakhari, S., Nov 2018, In : Alcohol. 72, p. 75-88 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Striatal activity correlates with stimulant-like effects of alcohol in healthy volunteers

Weafer, J., Ross, T. J., O’Connor, S., Stein, E. A., de Wit, H. & Childs, E., Dec 1 2018, In : Neuropsychopharmacology. 43, 13, p. 2532-2538 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Exposure-response relationships during free-access intravenous alcohol self-administration in nondependent drinkers: Influence of alcohol expectancies and impulsivity

Stangl, B. L., Vatsalya, V., Zametkin, M. R., Cooke, M. E., Plawecki, M. H., O'Connor, S. & Ramchandani, V. A., 2017, In : International Journal of Neuropsychopharmacology. 20, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Management of alcohol misuse in patients with liver diseases

Peng, J. L., Patel, M. P., McGee, B., Liang, T., Chandler, K., Tayarachakul, S., O'Connor, S. & Liangpunsakul, S., Mar 2017, In : Journal of Investigative Medicine. 65, 3, p. 673-680 8 p.

Research output: Contribution to journalReview article

2 Scopus citations
12 Scopus citations
3 Scopus citations
2016

Adolescent Women Induce Lower Blood Alcohol Levels Than Men in a Laboratory Alcohol Self-Administration Experiment

Jünger, E., Gan, G., Mick, I., Seipt, C., Markovic, A., Sommer, C., Plawecki, M. H., O'Connor, S., Smolka, M. N. & Zimmermann, U. S., Aug 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 8, p. 1769-1778 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

A prospective 5-year re-examination of alcohol response in heavy drinkers progressing in alcohol use disorder

King, A. C., Hasin, D., O'Connor, S. J., McNamara, P. J. & Cao, D., Mar 15 2016, In : Biological psychiatry. 79, 6, p. 489-498 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Differences in IV alcohol-induced dopamine release in the ventral striatum of social drinkers and nontreatment-seeking alcoholics

Yoder, K. K., Albrecht, D. S., Dzemidzic, M., Normandin, M. D., Federici, L. M., Graves, T., Herring, C. M., Hile, K. L., Walters, J. W., Liang, T., Plawecki, M. H., O'Connor, S. & Kareken, D. A., Mar 1 2016, In : Drug and Alcohol Dependence. 160, p. 163-169 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Gender-Specific Effects of Mood on Alcohol-Seeking Behaviors: Preliminary Findings Using Intravenous Alcohol Self-Administration

Cyders, M. A., Vanderveen, J. D., Plawecki, M., Millward, J. B., Hays, J., Kareken, D. A. & O'Connor, S., Feb 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Negative urgency, mood induction, and alcohol seeking behaviors

VanderVeen, J. D., Plawecki, M. H., Millward, J. B., Hays, J., Kareken, D. A., O'Connor, S. & Cyders, M. A., Aug 1 2016, In : Drug and Alcohol Dependence. 165, p. 151-158 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2015
13 Scopus citations

Beer self-administration provokes lateralized nucleus accumbens dopamine release in male heavy drinkers

Oberlin, B. G., Dzemidzic, M., Tran, S. M., Soeurt, C. M., O'Connor, S. J., Yoder, K. K. & Kareken, D. A., Jan 2015, In : Psychopharmacology. 232, 5, p. 861-870 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
6 Scopus citations

Integrating mRNA and miRNA weighted gene co-expression networks with eQTLs in the nucleus accumbens of subjects with alcohol dependence

Mamdani, M., Williamson, V., McMichael, G. O., Blevins, T., Aliev, F., Adkins, A., Hack, L., Bigdeli, T., Van Der Vaart, A. D., Web, B. T., Bacanu, S. A., Kalsi, G., Kendler, K. S., Miles, M. F., Dick, D., Riley, B. P., Dumur, C., Vladimirov, V. I., Hesselbrock, V., Edenberg, H. J. & 29 others, Nurnberger, J., Foroud, T., Kuperman, S., Kramer, J., Porjesz, B., Bierut, L., Goate, A., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Almasy, L., Taylor, R., Dick, D., Bauer, L., Koller, D. L., O'Connor, S., Wetherill, L., Xuei, X., Chan, G., Kang, S., Manz, N., Rangaswamy, M., Rohrbaugh, J., Wang, J. C., Brooks, A., Aliev, F., Parsian, A. & Reilly, M., Sep 18 2015, In : PloS one. 10, 9, e0137671.

Research output: Contribution to journalArticle

39 Scopus citations

Novel serum biomarkers for detection of excessive alcohol use

Liangpunsakul, S., Lai, X., Ross, R. A., Yu, Z., Modlik, E., Westerhold, C., Heathers, L., Paul, R., O'Connor, S., Crabb, D. W. & Witzmann, F., Mar 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 3, p. 556-565 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

The apéritif effect: Alcohol's effects on the brain's response to food aromas in women

Eiler, W. J. A., Džemidžic, M., Case, K. R., Soeurt, C. M., Armstrong, C. L. H., Mattes, R. D., O'Connor, S. J., Harezlak, J., Acton, A. J., Considine, R. V. & Kareken, D. A., Jul 1 2015, In : Obesity. 23, 7, p. 1386-1393 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Family history of alcoholism interacts with alcohol to affect brain regions involved in behavioral inhibition

Kareken, D. A., Dzemidzic, M., Wetherill, L., Eiler, W., Oberlin, B. G., Harezlak, J., Wang, Y. & O'Connor, S. J., Jul 1 2013, In : Psychopharmacology. 228, 2, p. 335-345 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Voluntary Intravenous Self-Administration of Alcohol Detects an Interaction Between GABAergic Manipulation and GABRG1 Polymorphism Genotype: A Pilot Study

Plawecki, M. H., Wetherill, L., Vitvitskiy, V., Kosobud, A., Zimmermann, U. S., Edenberg, H. J. & O'Connor, S., Jan 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, SUPPL.1, p. E152-E160

Research output: Contribution to journalArticle

18 Scopus citations
2012

Alcohol Exposure Rate Control Through Physiologically Based Pharmacokinetic Modeling

Plawecki, M. H., Zimmermann, U. S., Vitvitskiy, V., Doerschuk, P. C., Crabb, D. & O'Connor, S., Jun 2012, In : Alcoholism: Clinical and Experimental Research. 36, 6, p. 1042-1049 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

fMRI of the brain's response to stimuli experimentally paired with alcohol intoxication

Kareken, D. A., Grahame, N., Dzemidzic, M., Walker, M. J., Lehigh, C. A. & O'Connor, S. J., Jan 1 2012, In : Psychopharmacology. 220, 4, p. 787-797 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Limbic responses to reward cues correlate with antisocial trait density in heavy drinkers

Oberlin, B. G., Dzemidzic, M., Bragulat, V., Lehigh, C. A., Talavage, T., O'Connor, S. J. & Kareken, D. A., Mar 1 2012, In : NeuroImage. 60, 1, p. 644-652 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Reliability of striatal [ 11C]raclopride binding in smokers wearing transdermal nicotine patches

Yoder, K. K., Albrecht, D. S., Kareken, D. A., Federici, L. M., Perry, K. M., Patton, E. A., Zheng, Q. H., Mock, B. H., O'Connor, S. J. & Herring, C. M., Feb 1 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 2, p. 220-225 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Subjective Perceptions Associated with the Ascending and Descending Slopes of Breath Alcohol Exposure Vary with Recent Drinking History

Wetherill, L., Morzorati, S. L., Foroud, T., Windisch, K., Darlington, T., Zimmerman, U. S., Plawecki, M. H. & O'Connor, S. J., Jun 1 2012, In : Alcoholism: Clinical and Experimental Research. 36, 6, p. 1050-1057 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Bidirectional interactions between acute psychosocial stress and acute intravenous alcohol in healthy men

Childs, E., O'Connor, S. & de Wit, H., Oct 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 10, p. 1794-1803 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Characterization of human use of ethanol based on video games with ethanol rewards: Model, system identification and statistical performance

Ozil, I., Plawecki, M. H., Doerschuk, P. C. & O'Connor, S. J., Dec 1 2011, Conference Record of the 45th Asilomar Conference on Signals, Systems and Computers, ASILOMAR 2011. p. 1107-1111 5 p. 6190185. (Conference Record - Asilomar Conference on Signals, Systems and Computers).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Modeling alcohol self-administration in the human laboratory

Zimmermann, U. S., O’Connor, S. & Ramchandani, V. A., Jul 27 2011, In : Current Topics in Behavioral Neurosciences. 13, p. 315-353 39 p.

Research output: Contribution to journalArticle

39 Scopus citations

System identification to characterize human use of ethanol based on generative point-process models of video games with ethanol rewards

Ozil, I., Plawecki, M. H., Doerschuk, P. C. & O'Connor, S. J., Dec 26 2011, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. p. 2699-2702 4 p. 6090741. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Test-retest variability of [11C]raclopride-binding potential in nontreatment-seeking alcoholics

Yoder, K. K., Albrecht, D. S., Kareken, D. A., Federici, L. M., Perry, K. M., Patton, E. A., Zheng, Q. H., Mock, B. H., O'Connor, S. & Herring, C. M., Jul 1 2011, In : Synapse. 65, 7, p. 553-561 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2010

A polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI study

Kareken, D. A., Liang, T., Wetherill, L., Dzemidzic, M., Bragulat, V., Cox, C., Talavage, T., O'Connor, S. J. & Foroud, T., Dec 1 2010, In : Alcoholism: Clinical and Experimental Research. 34, 12, p. 2169-2178 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Family history of alcoholism mediates the frontal response to alcoholic drink odors and alcohol in at-risk drinkers

Kareken, D. A., Bragulat, V., Dzemidzic, M., Cox, C., Talavage, T., Davidson, D. & O'Connor, S. J., Mar 1 2010, In : NeuroImage. 50, 1, p. 267-276 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Obesity, smoking, and frontal brain dysfunction

Bauer, L., Dick, D., Bierut, L., Bucholz, K., Edenberg, H., Kuperman, S., Kramer, J., Nurnberger, J., O'Connor, S., Rice, J., Rohrbaugh, J., Schuckit, M., Tischfield, J., Porjesz, B. & Hesselbrock, V., Sep 1 2010, In : American Journal on Addictions. 19, 5, p. 391-400 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence

Chen, A. C. H., Manz, N., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger, J., O'Connor, S. J., Edenberg, H. J., Schuckit, M. A., Tischfield, J., Foroud, T., Bierut, L. J., Rohrbaugh, J., Rice, J. P., Goate, A., Hesselbrock, V. & Porjesz, B., Jun 2010, In : Alcoholism: Clinical and Experimental Research. 34, 6, p. 988-996 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2009

Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence

Chen, A. C. H., Tang, Y., Rangaswamy, M., Wang, J. C., Almasy, L., Foroud, T., Edenberg, H. J., Hesselbrock, V., Nurnberger, J., Kuperman, S., O'Connor, S. J., Schuckit, M. A., Bauer, L. O., Tischfield, J., Rice, J. P., Bierut, L., Goate, A. & Porjesz, B., Apr 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 3, p. 359-368 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Intravenous ethanol infusions can mimic the time course of breath alcohol concentrations following oral alcohol administration in healthy volunteers

Ramchandani, V. A., Plawecki, M., Li, T. K. & O'Connor, S., May 1 2009, In : Alcoholism: Clinical and Experimental Research. 33, 5, p. 938-944 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

In vivo wireless ethanol vapor detection in the Wistar rat

Cheney, C. P., Srijanto, B., Hedden, D. L., Gehl, A., Ferrell, T. L., Schultz, J., Engleman, E. A., McBride, W. J. & O'Connor, S., Apr 24 2009, In : Sensors and Actuators, B: Chemical. 138, 1, p. 264-269 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE)

Zimmermann, U. S., Mick, I., Laucht, M., Vitvitskiy, V., Plawecki, M. H., Mann, K. F. & O'Connor, S., Mar 1 2009, In : Psychopharmacology. 202, 4, p. 689-697 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Pharmacologic treatment for substance use disorders in children and adolescents

Plawecki, M. H., Erickson, C. A. & O'Connor, S., Sep 2009, In : Psychopharm Review. 44, 9, p. 65-72 8 p.

Research output: Contribution to journalArticle

Priming deficiency in male subjects at risk for alcoholism: The N4 during a lexical decision task

Roopesh, B. N., Rangaswamy, M., Kamarajan, C., Chorlian, D. B., Stimus, A., Bauer, L. O., Rohrbaugh, J., O'Connor, S. J., Kuperman, S., Schuckit, M. & Porjesz, B., Dec 1 2009, In : Alcoholism: Clinical and Experimental Research. 33, 12, p. 2027-2036 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

When what you see isn't what you get: Alcohol cues, alcohol administration, prediction error, and human striatal dopamine

Yoder, K. K., Morris, E. D., Constantinescu, C. C., Cheng, T. E., Normandin, M. D., O'Connor, S. J. & Kareken, D. A., Jan 1 2009, In : Alcoholism: Clinical and Experimental Research. 33, 1, p. 139-149 11 p.

Research output: Contribution to journalArticle

51 Scopus citations
2008

Alcohol sensitizes cerebral responses to the odors of alcoholic drinks: An fMRI study

Bragulat, V., Dzemidzic, M., Talavage, T., Davidson, D., O'Connor, S. J. & Kareken, D. A., Jul 1 2008, In : Alcoholism: Clinical and Experimental Research. 32, 7, p. 1124-1134 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Development and Pilot Validation of Computer-Assisted Self-Infusion of Ethanol (CASE): A New Method to Study Alcohol Self-Administration in Humans

Zimmermann, U. S., Mick, I., Vitvitskyi, V., Plawecki, M. H., Mann, K. F. & Connor, S. O., Jul 1 2008, In : Alcoholism: Clinical and Experimental Research. 32, 7, p. 1321-1328 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Estimation from PET data of transient changes in dopamine concentration induced by alcohol: Support for a non-parametric signal estimation method

Constantinescu, C. C., Yoder, K. K., Kareken, D. A., Bouman, C. A., O'Connor, S. J., Normandin, M. D. & Morris, E. D., Mar 7 2008, In : Physics in Medicine and Biology. 53, 5, p. 1353-1367 15 p.

Research output: Contribution to journalArticle

7 Scopus citations