Sean O'Connor

  • 5582 Citations
  • 45 h-Index
1983 …2020

Research output per year

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Publications

  • 5582 Citations
  • 45 h-Index
  • 115 Article
  • 7 Conference contribution
  • 4 Review article
1983

A model referenced method for the identification of evoked potential component wave forms

O'Connor, S. J., Tasman, A., Simon, R. H. & Hale, M. S., Feb 1983, In : Electroencephalography and Clinical Neurophysiology. 55, 2, p. 233-237 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
1984

A comparison of pressure-volume models in hydrocephalus

Simon, R. H., Lehman, R. A. W. & O'Connor, S. J., Jan 1 1984, In : Neurosurgery. 15, 5, p. 694-699 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Model referenced method of evoked potential analysis

O'Connor, S. J., Simon, R. H. & Tasman, A., Nov 1984, In : Electroencephalography and Clinical Neurophysiology/ Evoked Potentials. 59, 6, p. 497-503 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
1986

Correlates of increased risk for alcoholism in young men

O'Connor, S., Hesselbrock, V. & Allan, T., 1986, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 10, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

65 Scopus citations
1987

P3 amplitudes in two distinct tasks are decreased in young men with a history of paternal alcoholism

O'Connor, S., Hesselbrock, V., Tasman, A. & DePalma, N., Jan 1 1987, In : Alcohol. 4, 4, p. 323-330 8 p.

Research output: Contribution to journalArticle

75 Scopus citations
1988

Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism

Kaplan, R. F., Hesselbrock, V. M., O'Connor, S. & Depalma, N., 1988, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 12, 6, p. 873-885 13 p.

Research output: Contribution to journalArticle

53 Scopus citations
1989

Amplitude modulated frequency response during acute cocaine intoxication in rabbits

O'Connor, S., Kuwada, S., DePalma, N., Stanford, T. & Tasman, A., Dec 1 1989, NIDA Research Monograph Series. 95 ed. p. 331-332 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Neurolectic correlates of nonsteroidal analgesia

O'Connor, S., Tasman, A., DePalma, N. & Zaccheo, S., 1989, NIDA Research Monograph Series. 95 ed. p. 397-398 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1990

The application of electrophysiology to research in alcoholism

O'Connor, S. & Tasman, A., Jan 1 1990, In : Journal of Neuropsychiatry and Clinical Neurosciences. 2, 2, p. 149-158 10 p.

Research output: Contribution to journalReview article

3 Scopus citations
1992

Variation in evoked potential measures over the menstrual cycle: A pilot study

Kluck, N., O'Connor, S., Hesselbrock, V., Tasman, A., Maier, D. & Bauer, L., Nov 1992, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 16, 6, p. 901-911 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
1993
42 Scopus citations
1994

Frontal P300 Decrements in Antisocial Personality Disorder

Bauer, L. O., O'Connor, S. & Hesselbrock, V. M., Dec 1994, In : Alcoholism: Clinical and Experimental Research. 18, 6, p. 1300-1305 6 p.

Research output: Contribution to journalArticle

120 Scopus citations
104 Scopus citations
42 Scopus citations

P300 from an auditory oddball task: inter-laboratory consistency

Alexander, J. E., Polich, J., Bloom, F. E., Bauer, L. O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S. J., Porjesz, B. & Begleiter, H., Jun 1994, In : International Journal of Psychophysiology. 17, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Reduced P3 amplitudes are associated with both a family history of alcoholism and antisocial personality disorder

O'Connor, S., Bauer, L., Tasman, A. & Hesselbrock, V., Dec 1994, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 18, 8, p. 1307-1321 15 p.

Research output: Contribution to journalArticle

76 Scopus citations

Visual P300: An interlaboratory consistency study

Cohen, H. L., Wang, W., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S. J., Rohrbaugh, J. & Begleiter, H., Jan 1 1994, In : Alcohol. 11, 6, p. 583-587 5 p.

Research output: Contribution to journalArticle

31 Scopus citations
1995

Multi-center N400 ERP consistency using a primed and unprimed word paradigm

Kuperman, S., Porjesz, B., Arndt, S., Bauer, L., Begleiter, H., Cizadlo, T., O'Connor, S. & Rohrbaugh, J., Jun 1995, In : Electroencephalography and Clinical Neurophysiology. 94, 6, p. 462-470 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

P300 hemispheric amplitude asymmetries from a visual oddball task

ALEXANDER, JOEL. E., PORJESZ, BERNICE., BAUER, LANCE. O., KUPERMAN, SAMUEL., MORZORATI, SANDRA., O'CONNOR, SEAN. J., ROHRBAUGH, JOHN., BEGLEITER, HENRI. & POLICH, JOHN., Sep 1995, In : Psychophysiology. 32, 5, p. 467-475 9 p.

Research output: Contribution to journalArticle

61 Scopus citations
1996

Alcohol effects on the heritability of EEG spectral power

Sorbel, J., Morzorati, S., O'Connor, S., Li, T. K. & Christian, J. C., Dec 1 1996, In : Alcoholism: Clinical and Experimental Research. 20, 9, p. 1523-1527 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Genetic analysis of the resting electroencephalographic power spectrum in human twins

Christian, J. C., Morzorati, S., Norton, J. A., Williams, C. J., O'Connor, S. & Li, T. K., Sep 1996, In : Psychophysiology. 33, 5, p. 584-591 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Hemispheric differences for P300 amplitude from an auditory oddball task

Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J., Feb 3 1996, In : International Journal of Psychophysiology. 21, 2-3, p. 189-196 8 p.

Research output: Contribution to journalArticle

58 Scopus citations
1997

A graphical technique for displaying correlation matrices

Koziol, J. A., Alexander, J. E., Bauers, L. O., Kuperman, S., Morzorati, S., O’connor, S. J., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J., Nov 1997, In : American Statistician. 51, 4, p. 301-304 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

P300 topography of Amplitude/Latency correlations

Polich, J., Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Porjesz, B., Rohrbaugh, J. & Begleiter, H., Aug 20 1997, In : Brain Topography. 9, 4, p. 275-282 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

Slow brain potentials in a visual-spatial memory task: Topographic distribution and inter-laboratory consistency

Rohrbaugh, J. W., Dunham, D. N., Stewart, P. A., Bauer, L. O., Kuperman, S., O'Connor, S. J., Porjesz, B. & Begleiter, H., Feb 1 1997, In : International Journal of Psychophysiology. 25, 2, p. 111-122 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
1998

Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: Preliminary results from the COGA project

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H. J., Foroud, T., Goate, A., Litke, A., Chorlian, D. B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L. O., Kuperman, S., O'Connor, S. J. & Rohrbaugh, J., Sep 1 1998, In : Alcoholism: Clinical and Experimental Research. 22, 6, p. 1317-1323 7 p.

Research output: Contribution to journalArticle

105 Scopus citations
126 Scopus citations

Gender differences in alcohol metabolism: Relationship to liver volume and effect of adjusting for body mass

Kwo, P. Y., Ramchandani, V. A., O'Connor, S., Amann, D., Carr, L. G., Sandrasegaran, K., Kopecky, K. K. & Li, T. K., Jan 1 1998, In : Gastroenterology. 115, 6, p. 1552-1557 6 p.

Research output: Contribution to journalArticle

125 Scopus citations

Quantitative trait loci analysis of human event-related brain potentials: P3 voltage

Begleiter, H., Porjesz, B., Reich, T., Edenberg, H. J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., Bauer, L. O., O'Connor, S. J., Chorlian, D. B., Li, T. K., Conneally, P. M., Hesselbrock, V., Rice, J. P., Schuckit, M. A. & 4 others, Cloninger, R., Nurnberger, J., Crowe, R. & Bloom, F. E., Apr 1 1998, In : Electroencephalography and Clinical Neurophysiology - Evoked Potentials. 108, 3, p. 244-250 7 p.

Research output: Contribution to journalArticle

137 Scopus citations
1999

A physiologically-based pharmacokinetic (PBPK) model for alcohol facilitates rapid BrAC clamping

Ramchandani, V. A., Bolane, J., Li, T. K. & O'Connor, S., Apr 1 1999, In : Alcoholism: Clinical and Experimental Research. 23, 4, p. 617-623 7 p.

Research output: Contribution to journalArticle

123 Scopus citations

A preliminary study of acute responses to clamped alcohol concentration and family history of alcoholism

Ramchandani, V. A., O'Connor, S., Blekher, T., Kareken, D., Morzorati, S., Nurnberger, J. & Li, T. K., Jan 1 1999, In : Alcoholism: Clinical and Experimental Research. 23, 8, 1 p.

Research output: Contribution to journalArticle

52 Scopus citations

A twin study of genetic influences on the acute adaptation of the EEG to alcohol

O'Connor, S., Sorbel, J., Morzorati, S., Li, T. K. & Christian, J. C., Mar 1999, In : Alcoholism: Clinical and Experimental Research. 23, 3, p. 494-501 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Heritability of event-related brain potentials in families with a history of alcoholism

Almasy, L., Porjesz, B., Blangero, J., Chorlian, D. B., O'Connor, S. J., Kuperman, S., Rohrbaugh, J., Bauer, L. O., Reich, T., Polich, J. & Begleiter, H., Aug 20 1999, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 88, 4, p. 383-390 8 p.

Research output: Contribution to journalArticle

67 Scopus citations
2000

Frontal P300 decrements, alcohol dependence, and antisocial personality disorder

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J. & Begleiter, H., Jun 1 2000, In : Biological psychiatry. 47, 12, p. 1064-1071 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

PBPK modeling as a basis for achieving a steady of 60 ± 5 mg% within ten minutes

O'Connor, S., Ramchandani, V. A. & Li, T. K., Apr 1 2000, In : Alcoholism: Clinical and Experimental Research. 24, 4, p. 426-427 2 p.

Research output: Contribution to journalArticle

37 Scopus citations

The p300 brain potential is reduced in smokers

Anokhin, A. P., Vedeniapin, A. B., Sirevaag, E. J., Bauer, L. O., O'Connor, S. J., Kuperman, S., Porjesz, B., Reich, T., Begleiter, H., Polich, J. & Rohrbaugh, J. W., Jan 1 2000, In : Psychopharmacology. 149, 4, p. 409-413 5 p.

Research output: Contribution to journalArticle

78 Scopus citations
2001

Genetic and environmental influences on alcohol metabolism in humans

Li, T. K., Yin, S. J., Crabb, D. W., O'Connor, S. & Ramchandani, V. A., Jan 1 2001, In : Alcoholism: Clinical and Experimental Research. 25, 1, p. 136-144 9 p.

Research output: Contribution to journalArticle

104 Scopus citations

Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H. J. & O'Connor, S. J., 2001, In : American Journal of Human Genetics. 68, 1, p. 128-135 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

P300 event-related potential amplitude as an endophenotype of alcoholism - Evidence from the Collaborative Study on the Genetics of Alcoholism

Hesselbrock, V., Begleiter, H., Porjesz, B., O'Connor, S. & Bauer, L., Feb 6 2001, In : Journal of Biomedical Science. 8, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

93 Scopus citations
2002

Beta power in the EEG of alcoholics

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Wang, K., Jones, K. A., Bauer, L. O., Rohrbaugh, J., O'Connor, S. J., Kuperman, S., Reich, T. & Begleiter, H., Oct 15 2002, In : Biological psychiatry. 52, 8, p. 831-842 12 p.

Research output: Contribution to journalArticle

200 Scopus citations

Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D. B., Stimus, A. T., Kuperman, S., O'Connor, S. J., Rohrbaugh, J., Bauer, L. O., Edenberg, H. J., Goate, A., Rice, J. P. & Reich, T., Oct 2002, In : Biological Psychology. 61, 1-2, p. 229-248 20 p.

Research output: Contribution to journalArticle

89 Scopus citations

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus

Porjesz, B., Almasy, L., Edenberg, H. J., Wang, K., Chorlian, D. B., Foroud, T., Goate, A., Rice, J. P., O'Connor, S. J., Rohrbaugh, J., Kuperman, S., Bauer, L. O., Crowe, R. R., Schuckit, M. A., Hesselbrock, V., Conneally, P. M., Tischfield, J. A., Li, T. K., Reich, T. & Begleiter, H., Mar 19 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 6, p. 3729-3733 5 p.

Research output: Contribution to journalArticle

235 Scopus citations

Maintaining steady state arterial alcohol levels in rats by using a physiologically based pharmacokinetic model

Morzorati, S. L., Ramchandani, V. A., Li, T. K. & O'Connor, S., Nov 1 2002, In : Alcohol. 28, 3, p. 189-195 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Recent drinking history: Association with family history of alcoholism and the acute response to alcohol during a 60 mg% clamp

Ramchandani, V. A., Flury, L., Morzorati, S. L., Kareken, D., Blekher, T., Foroud, T., Li, T. K. & O'Connor, S., Nov 2002, In : Journal of Studies on Alcohol. 63, 6, p. 734-744 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Response of saccadic eye movements to alcohol in African American and non-Hispanic white college students

Blekher, T., Beard, J. D., O'Connor, S., Orr, W. E., Ramchandani, V. A., Miller, K., Yee, R. D. & Li, T. K., Jan 1 2002, In : Alcoholism: Clinical and Experimental Research. 26, 2, p. 232-238 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Saccadic eye movements are associated with a family history of alcoholism at baseline and after exposure to alcohol

Blekher, T., Ramchandani, V. A., Flury, L., Foroud, T., Kareken, D., Yee, R. D., Li, T. K. & O'Connor, S., Oct 2002, In : Alcoholism: Clinical and Experimental Research. 26, 10, p. 1568-1573 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Self-reported subjective perception of intoxication reflects family history of alcoholism when breath alcohol levels are constant

Morzorati, S. L., Ramchandani, V. A., Flury, L., Li, T. K. & O'Connor, S., Aug 2002, In : Alcoholism: Clinical and Experimental Research. 26, 8, p. 1299-1306 8 p.

Research output: Contribution to journalArticle

89 Scopus citations
2003

Theta power in the EEG of alcoholics

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Choi, K., Jones, K. A., Wang, K., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T. & Begleiter, H., Apr 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 4, p. 607-615 9 p.

Research output: Contribution to journalArticle

71 Scopus citations
2004

A family study of alcohol dependence: Coaggregation of multiple disorders in relatives of alcohol-dependent probands

Nurnberger, J. I., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E. T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A. L., Kuperman, S., Hesselbrock, V. & Porjesz, B., Dec 1 2004, In : Archives of general psychiatry. 61, 12, p. 1246-1256 11 p.

Research output: Contribution to journalArticle

173 Scopus citations

Alcohol Dehydrogenase Polymorphisms Influence Alcohol-Elimination Rates in a Male Jewish Population

Neumark, Y. D., Friedlander, Y., Durst, R., Leitersdorf, E., Jaffe, D., Ramchandani, V. A., O'Connor, S., Carr, L. G. & Li, T. K., Jan 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

124 Scopus citations