Sean O'Connor

  • 5582 Citations
  • 45 h-Index
1983 …2020

Research output per year

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Publications

  • 5582 Citations
  • 45 h-Index
  • 115 Article
  • 7 Conference contribution
  • 4 Review article
Article

A cholinergic receptor gene (CHRM2) affects event-related oscillations

Jones, K. A., Porjesz, B., Almasy, L., Bierut, L., Dick, D., Goate, A., Hinrichs, A., Rice, J. P., Wang, J. C., Bauer, L. O., Crowe, R., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger, J., O'Connor, S. J., Rohrbaugh, J., Schuckit, M. A., Tischfield, J., Edenberg, H. J. & 1 others, Begleiter, H., Sep 1 2006, In : Behavior Genetics. 36, 5, p. 627-639 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

A comparison of pressure-volume models in hydrocephalus

Simon, R. H., Lehman, R. A. W. & O'Connor, S. J., Jan 1 1984, In : Neurosurgery. 15, 5, p. 694-699 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
14 Scopus citations

Adolescent Women Induce Lower Blood Alcohol Levels Than Men in a Laboratory Alcohol Self-Administration Experiment

Jünger, E., Gan, G., Mick, I., Seipt, C., Markovic, A., Sommer, C., Plawecki, M. H., O'Connor, S., Smolka, M. N. & Zimmermann, U. S., Aug 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 8, p. 1769-1778 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

A family study of alcohol dependence: Coaggregation of multiple disorders in relatives of alcohol-dependent probands

Nurnberger, J. I., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E. T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A. L., Kuperman, S., Hesselbrock, V. & Porjesz, B., Dec 1 2004, In : Archives of general psychiatry. 61, 12, p. 1246-1256 11 p.

Research output: Contribution to journalArticle

173 Scopus citations

A graphical technique for displaying correlation matrices

Koziol, J. A., Alexander, J. E., Bauers, L. O., Kuperman, S., Morzorati, S., O’connor, S. J., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J., Nov 1997, In : American Statistician. 51, 4, p. 301-304 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Alcohol affects the P3 component of an adaptive stop signal task ERP

Plawecki, M. H., Windisch, K. A., Wetherill, L., Kosobud, A. E. K., Dzemidzic, M., Kareken, D. A. & O'Connor, S. J., Aug 2018, In : Alcohol. 70, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alcohol Dehydrogenase Polymorphisms Influence Alcohol-Elimination Rates in a Male Jewish Population

Neumark, Y. D., Friedlander, Y., Durst, R., Leitersdorf, E., Jaffe, D., Ramchandani, V. A., O'Connor, S., Carr, L. G. & Li, T. K., Jan 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

124 Scopus citations

Alcohol effects on the heritability of EEG spectral power

Sorbel, J., Morzorati, S., O'Connor, S., Li, T. K. & Christian, J. C., Dec 1 1996, In : Alcoholism: Clinical and Experimental Research. 20, 9, p. 1523-1527 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Alcohol Exposure Rate Control Through Physiologically Based Pharmacokinetic Modeling

Plawecki, M. H., Zimmermann, U. S., Vitvitskiy, V., Doerschuk, P. C., Crabb, D. & O'Connor, S., Jun 2012, In : Alcoholism: Clinical and Experimental Research. 36, 6, p. 1042-1049 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Alcohol intoxication progressively impairs drivers' capacity to detect important environmental stimuli

Plawecki, M. H., Koskie, S., Kosobud, A., Justiss, M. D. & O'Connor, S., Dec 2018, In : Pharmacology Biochemistry and Behavior. 175, p. 62-68 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Alcohol-Related Olfactory Cues Activate the Nucleus Accumbens and Ventral Tegmental Area in High-Risk Drinkers: Preliminary Findings

Kareken, D. A., Claus, E. D., Sabri, M., Dzemidzic, M., Kosobud, A. E. K., Radnovich, A. J., Hector, D., Ramchandani, V. A., O'Connor, S. J., Lowe, M. & Li, T. K., Apr 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 4, p. 550-557 8 p.

Research output: Contribution to journalArticle

86 Scopus citations

Alcohol sensitizes cerebral responses to the odors of alcoholic drinks: An fMRI study

Bragulat, V., Dzemidzic, M., Talavage, T., Davidson, D., O'Connor, S. J. & Kareken, D. A., Jul 1 2008, In : Alcoholism: Clinical and Experimental Research. 32, 7, p. 1124-1134 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

A model referenced method for the identification of evoked potential component wave forms

O'Connor, S. J., Tasman, A., Simon, R. H. & Hale, M. S., Feb 1983, In : Electroencephalography and Clinical Neurophysiology. 55, 2, p. 233-237 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: Preliminary results from the COGA project

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H. J., Foroud, T., Goate, A., Litke, A., Chorlian, D. B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L. O., Kuperman, S., O'Connor, S. J. & Rohrbaugh, J., Sep 1 1998, In : Alcoholism: Clinical and Experimental Research. 22, 6, p. 1317-1323 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

A physiologically-based pharmacokinetic (PBPK) model for alcohol facilitates rapid BrAC clamping

Ramchandani, V. A., Bolane, J., Li, T. K. & O'Connor, S., Apr 1 1999, In : Alcoholism: Clinical and Experimental Research. 23, 4, p. 617-623 7 p.

Research output: Contribution to journalArticle

123 Scopus citations

A polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI study

Kareken, D. A., Liang, T., Wetherill, L., Dzemidzic, M., Bragulat, V., Cox, C., Talavage, T., O'Connor, S. J. & Foroud, T., Dec 1 2010, In : Alcoholism: Clinical and Experimental Research. 34, 12, p. 2169-2178 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

A preliminary study of acute responses to clamped alcohol concentration and family history of alcoholism

Ramchandani, V. A., O'Connor, S., Blekher, T., Kareken, D., Morzorati, S., Nurnberger, J. & Li, T. K., Jan 1 1999, In : Alcoholism: Clinical and Experimental Research. 23, 8, 1 p.

Research output: Contribution to journalArticle

52 Scopus citations

A prospective 5-year re-examination of alcohol response in heavy drinkers progressing in alcohol use disorder

King, A. C., Hasin, D., O'Connor, S. J., McNamara, P. J. & Cao, D., Mar 15 2016, In : Biological psychiatry. 79, 6, p. 489-498 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence

Chen, A. C. H., Tang, Y., Rangaswamy, M., Wang, J. C., Almasy, L., Foroud, T., Edenberg, H. J., Hesselbrock, V., Nurnberger, J., Kuperman, S., O'Connor, S. J., Schuckit, M. A., Bauer, L. O., Tischfield, J., Rice, J. P., Bierut, L., Goate, A. & Porjesz, B., Apr 5 2009, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 3, p. 359-368 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

A twin study of genetic influences on the acute adaptation of the EEG to alcohol

O'Connor, S., Sorbel, J., Morzorati, S., Li, T. K. & Christian, J. C., Mar 1999, In : Alcoholism: Clinical and Experimental Research. 23, 3, p. 494-501 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Beer self-administration provokes lateralized nucleus accumbens dopamine release in male heavy drinkers

Oberlin, B. G., Dzemidzic, M., Tran, S. M., Soeurt, C. M., O'Connor, S. J., Yoder, K. K. & Kareken, D. A., Jan 2015, In : Psychopharmacology. 232, 5, p. 861-870 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism

Kaplan, R. F., Hesselbrock, V. M., O'Connor, S. & Depalma, N., 1988, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 12, 6, p. 873-885 13 p.

Research output: Contribution to journalArticle

53 Scopus citations

Beta power in the EEG of alcoholics

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Wang, K., Jones, K. A., Bauer, L. O., Rohrbaugh, J., O'Connor, S. J., Kuperman, S., Reich, T. & Begleiter, H., Oct 15 2002, In : Biological psychiatry. 52, 8, p. 831-842 12 p.

Research output: Contribution to journalArticle

200 Scopus citations

Bidirectional interactions between acute psychosocial stress and acute intravenous alcohol in healthy men

Childs, E., O'Connor, S. & de Wit, H., Oct 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 10, p. 1794-1803 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
126 Scopus citations

Comparison of Subjective Responses to Oral and Intravenous Alcohol Administration Under Similar Systemic Exposures

Plawecki, M. H., Durrani, A. M., Boes, J., Wetherill, L., Kosobud, A., O'Connor, S. & Ramchandani, V. A., Apr 2019, In : Alcoholism: Clinical and Experimental Research. 43, 4, p. 597-606 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Correlates of increased risk for alcoholism in young men

O'Connor, S., Hesselbrock, V. & Allan, T., 1986, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 10, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Delta and theta oscillations as risk markers in adolescent offspring of alcoholics

Rangaswamy, M., Jones, K. A., Porjesz, B., Chorlian, D. B., Padmanabhapillai, A., Kamarajan, C., Kuperman, S., Rohrbaugh, J., O'Connor, S. J., Bauer, L. O., Schuckit, M. A. & Begleiter, H., Jan 1 2007, In : International Journal of Psychophysiology. 63, 1, p. 3-15 13 p.

Research output: Contribution to journalArticle

75 Scopus citations

Development and Pilot Validation of Computer-Assisted Self-Infusion of Ethanol (CASE): A New Method to Study Alcohol Self-Administration in Humans

Zimmermann, U. S., Mick, I., Vitvitskyi, V., Plawecki, M. H., Mann, K. F. & Connor, S. O., Jul 1 2008, In : Alcoholism: Clinical and Experimental Research. 32, 7, p. 1321-1328 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Differences in IV alcohol-induced dopamine release in the ventral striatum of social drinkers and nontreatment-seeking alcoholics

Yoder, K. K., Albrecht, D. S., Dzemidzic, M., Normandin, M. D., Federici, L. M., Graves, T., Herring, C. M., Hile, K. L., Walters, J. W., Liang, T., Plawecki, M. H., O'Connor, S. & Kareken, D. A., Mar 1 2016, In : Drug and Alcohol Dependence. 160, p. 163-169 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Dopamine D2 receptor availability is associated with subjective responses to alcohol

Yoder, K. K., Kareken, D. A., Seyoum, R. A., O'Connor, S. J., Wang, C., Zheng, Q. H., Mock, B. & Morris, E. D., Jun 1 2005, In : Alcoholism: Clinical and Experimental Research. 29, 6, p. 965-970 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Estimation from PET data of transient changes in dopamine concentration induced by alcohol: Support for a non-parametric signal estimation method

Constantinescu, C. C., Yoder, K. K., Kareken, D. A., Bouman, C. A., O'Connor, S. J., Normandin, M. D. & Morris, E. D., Mar 7 2008, In : Physics in Medicine and Biology. 53, 5, p. 1353-1367 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task

Padmanabhapillai, A., Tang, Y., Ranganathan, M., Rangaswamy, M., Jones, K. A., Chorlian, D. B., Kamarajan, C., Stimus, A., Kuperman, S., Rohrbaugh, J., O'Connor, S. J., Bauer, L. O., Schuckit, M. A., Begleiter, H. & Porjesz, B., Nov 1 2006, In : International Journal of Psychophysiology. 62, 2, p. 262-271 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Exposure-response relationships during free-access intravenous alcohol self-administration in nondependent drinkers: Influence of alcohol expectancies and impulsivity

Stangl, B. L., Vatsalya, V., Zametkin, M. R., Cooke, M. E., Plawecki, M. H., O'Connor, S. & Ramchandani, V. A., 2017, In : International Journal of Neuropsychopharmacology. 20, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Family history of alcoholism interacts with alcohol to affect brain regions involved in behavioral inhibition

Kareken, D. A., Dzemidzic, M., Wetherill, L., Eiler, W., Oberlin, B. G., Harezlak, J., Wang, Y. & O'Connor, S. J., Jul 1 2013, In : Psychopharmacology. 228, 2, p. 335-345 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Family history of alcoholism mediates the frontal response to alcoholic drink odors and alcohol in at-risk drinkers

Kareken, D. A., Bragulat, V., Dzemidzic, M., Cox, C., Talavage, T., Davidson, D. & O'Connor, S. J., Mar 1 2010, In : NeuroImage. 50, 1, p. 267-276 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

fMRI of the brain's response to stimuli experimentally paired with alcohol intoxication

Kareken, D. A., Grahame, N., Dzemidzic, M., Walker, M. J., Lehigh, C. A. & O'Connor, S. J., Jan 1 2012, In : Psychopharmacology. 220, 4, p. 787-797 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Frontal P300 decrements, alcohol dependence, and antisocial personality disorder

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J. & Begleiter, H., Jun 1 2000, In : Biological psychiatry. 47, 12, p. 1064-1071 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

Frontal P300 Decrements in Antisocial Personality Disorder

Bauer, L. O., O'Connor, S. & Hesselbrock, V. M., Dec 1994, In : Alcoholism: Clinical and Experimental Research. 18, 6, p. 1300-1305 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

Gender differences in alcohol metabolism: Relationship to liver volume and effect of adjusting for body mass

Kwo, P. Y., Ramchandani, V. A., O'Connor, S., Amann, D., Carr, L. G., Sandrasegaran, K., Kopecky, K. K. & Li, T. K., Jan 1 1998, In : Gastroenterology. 115, 6, p. 1552-1557 6 p.

Research output: Contribution to journalArticle

125 Scopus citations

Gender-Specific Effects of Mood on Alcohol-Seeking Behaviors: Preliminary Findings Using Intravenous Alcohol Self-Administration

Cyders, M. A., Vanderveen, J. D., Plawecki, M., Millward, J. B., Hays, J., Kareken, D. A. & O'Connor, S., Feb 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
6 Scopus citations

Genetic analysis of the resting electroencephalographic power spectrum in human twins

Christian, J. C., Morzorati, S., Norton, J. A., Williams, C. J., O'Connor, S. & Li, T. K., Sep 1996, In : Psychophysiology. 33, 5, p. 584-591 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Genetic and environmental influences on alcohol metabolism in humans

Li, T. K., Yin, S. J., Crabb, D. W., O'Connor, S. & Ramchandani, V. A., Jan 1 2001, In : Alcoholism: Clinical and Experimental Research. 25, 1, p. 136-144 9 p.

Research output: Contribution to journalArticle

104 Scopus citations

Genetic influences on bipolar EEG power spectra

Tang, Y., Chorlian, D. B., Rangaswamy, M., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S., Rohrbaugh, J., Schuckit, M., Stimus, A. & Begleiter, H., Jul 1 2007, In : International Journal of Psychophysiology. 65, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H. J. & O'Connor, S. J., 2001, In : American Journal of Human Genetics. 68, 1, p. 128-135 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Hemispheric differences for P300 amplitude from an auditory oddball task

Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J., Feb 3 1996, In : International Journal of Psychophysiology. 21, 2-3, p. 189-196 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Heritability of bipolar EEG spectra in a large sib-pair population

Tang, Y., Chorlian, D. B., Rangaswamy, M., O'Connor, S., Taylor, R., Rohrbaugh, J., Porjesz, B. & Begleiter, H., Mar 1 2007, In : Behavior Genetics. 37, 2, p. 302-313 12 p.

Research output: Contribution to journalArticle

8 Scopus citations