Sean O'Connor

  • 5381 Citations
  • 44 h-Index
1983 …2019
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Publications 1983 2019

  • 5381 Citations
  • 44 h-Index
  • 117 Article
  • 6 Conference contribution
  • 1 Review article
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Article
1983
9 Citations (Scopus)

A model referenced method for the identification of evoked potential component wave forms

O'Connor, S., Tasman, A., Simon, R. H. & Hale, M. S., 1983, In : Electroencephalography and Clinical Neurophysiology. 55, 2, p. 233-237 5 p.

Research output: Contribution to journalArticle

Neurophysiology
Visual Evoked Potentials
Visual Cortex
Evoked Potentials
Anesthetics
1984
5 Citations (Scopus)

A comparison of pressure-volume models in hydrocephalus

Simon, R. H., Lehman, R. A. W. & O'Connor, S., 1984, In : Neurosurgery. 15, 5, p. 694-699 6 p.

Research output: Contribution to journalArticle

Hydrocephalus
Pressure
6 Citations (Scopus)

Model referenced method of evoked potential analysis

O'Connor, S., Simon, R. H. & Tasman, A., 1984, In : Electroencephalography and Clinical Neurophysiology/ Evoked Potentials. 59, 6, p. 497-503 7 p.

Research output: Contribution to journalArticle

Evoked Potentials
1986
65 Citations (Scopus)

Correlates of increased risk for alcoholism in young men

O'Connor, S., Hesselbrock, V. & Allan, T., 1986, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 10, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

Fathers
Alcoholism
Drinking
Alcoholics
Evoked Potentials
1987
75 Citations (Scopus)

P3 amplitudes in two distinct tasks are decreased in young men with a history of paternal alcoholism

O'Connor, S., Hesselbrock, V., Tasman, A. & DePalma, N., 1987, In : Alcohol. 4, 4, p. 323-330 8 p.

Research output: Contribution to journalArticle

Evoked Potentials
alcoholism
Alcoholism
stimulus
paradigm
1988
53 Citations (Scopus)

Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism

Kaplan, R. F., Hesselbrock, V. M., O'Connor, S. & Depalma, N., 1988, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 12, 6, p. 873-885 13 p.

Research output: Contribution to journalArticle

Alcoholism
Electroencephalography
Placebos
Alcohols
Alcohol Drinking
1990
3 Citations (Scopus)

The application of electrophysiology to research in alcoholism

O'Connor, S. & Tasman, A., 1990, In : Journal of Neuropsychiatry and Clinical Neurosciences. 2, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

Chronic Brain Damage
Mental Processes
Neuropsychological Tests
Electrophysiology
Alcohol Drinking
1992
15 Citations (Scopus)

Variation in evoked potential measures over the menstrual cycle: A pilot study

Kluck, N., O'Connor, S., Hesselbrock, V., Tasman, A., Maier, D. & Bauer, L., 1992, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 16, 6, p. 901-911 11 p.

Research output: Contribution to journalArticle

Menstrual Cycle
Evoked Potentials
Menstruation
Luteinizing Hormone
Reaction Time
1993
42 Citations (Scopus)
Antisocial Personality Disorder
Alcoholism
P300 Event-Related Potentials
Electrodes
1994
119 Citations (Scopus)

Frontal P300 decrements in antisocial personality disorder

Bauer, L. O., O'Connor, S. & Hesselbrock, V. M., 1994, In : Alcoholism: Clinical and Experimental Research. 18, 6, p. 1300-1305 6 p.

Research output: Contribution to journalArticle

Antisocial Personality Disorder
Brain
Electrodes
Evoked Potentials
Alcoholics
103 Citations (Scopus)
Evoked Potentials
Likelihood Functions
Dizygotic Twins
Monozygotic Twins
Temporal Lobe
42 Citations (Scopus)
Antisocial Personality Disorder
Alcoholism
P300 Event-Related Potentials
Young Adult
28 Citations (Scopus)

P300 from an auditory oddball task: inter-laboratory consistency

Alexander, J. E., Polich, J., Bloom, F. E., Bauer, L. O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S., Porjesz, B. & Begleiter, H., 1994, In : International Journal of Psychophysiology. 17, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

Evoked Potentials
Scalp
Cognition
Equipment and Supplies
Discrimination (Psychology)
76 Citations (Scopus)

Reduced P3 amplitudes are associated with both a family history of alcoholism and antisocial personality disorder

O'Connor, S., Bauer, L., Tasman, A. & Hesselbrock, V., 1994, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 18, 8, p. 1307-1321 15 p.

Research output: Contribution to journalArticle

Antisocial Personality Disorder
Alcoholism
Evoked Potentials
Research
Reaction Time
30 Citations (Scopus)

Visual P300: An interlaboratory consistency study

Cohen, H. L., Wang, W., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S., Rohrbaugh, J. & Begleiter, H., 1994, In : Alcohol. 11, 6, p. 583-587 5 p.

Research output: Contribution to journalArticle

alcoholism
Alcoholism
P300 Event-Related Potentials
Design of experiments
stimulus
1995
15 Citations (Scopus)

Multi-center N400 ERP consistency using a primed and unprimed word paradigm

Kuperman, S., Porjesz, B., Arndt, S., Bauer, L., Begleiter, H., Cizadlo, T., O'Connor, S. & Rohrbaugh, J., 1995, In : Electroencephalography and Clinical Neurophysiology. 94, 6, p. 462-470 9 p.

Research output: Contribution to journalArticle

Evoked Potentials
Electrophysiology
Reaction Time
Meta-Analysis
Young Adult
61 Citations (Scopus)

P300 hemispheric amplitude asymmetries from a visual oddball task

Alexander, J. E., Porjesz, B., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S., Rohrbaugh, J., Begleiter, H. & Polich, J., 1995, In : Psychophysiology. 32, 5, p. 467-475 9 p.

Research output: Contribution to journalArticle

Electrodes
P300 Event-Related Potentials
1996
25 Citations (Scopus)

Alcohol effects on the heritability of EEG spectral power

Sorbel, J., Morzorati, S., O'Connor, S., Li, T. K. & Christian, J. C., 1996, In : Alcoholism: Clinical and Experimental Research. 20, 9, p. 1523-1527 5 p.

Research output: Contribution to journalArticle

Electroencephalography
Alcohols
Viverridae
Dizygotic Twins
Power spectral density
44 Citations (Scopus)

Genetic analysis of the resting electroencephalographic power spectrum in human twins

Christian, J. C., Morzorati, S., Norton, J. A., Williams, C. J., O'Connor, S. & Li, T. K., Sep 1996, In : Psychophysiology. 33, 5, p. 584-591 8 p.

Research output: Contribution to journalArticle

Electroencephalography
Twin Studies
Genes
Genetic Models
Dizygotic Twins
58 Citations (Scopus)

Hemispheric differences for P300 amplitude from an auditory oddball task

Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J., Feb 3 1996, In : International Journal of Psychophysiology. 21, 2-3, p. 189-196 8 p.

Research output: Contribution to journalArticle

Electrodes
P300 Event-Related Potentials
1997
4 Citations (Scopus)

A Graphical Technique for Displaying Correlation Matrices

Koziol, J. A., Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J., Nov 1997, In : American Statistician. 51, 4, p. 301-304 4 p.

Research output: Contribution to journalArticle

Correlation Matrix
Graphical Methods
Immediately
Equality
Experimental Data
91 Citations (Scopus)

P300 topography of Amplitude/Latency correlations

Polich, J., Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S., Porjesz, B., Rohrbaugh, J. & Begleiter, H., 1997, In : Brain Topography. 9, 4, p. 275-282 8 p.

Research output: Contribution to journalArticle

Evoked Potentials
Brain
Scalp
Electrodes
14 Citations (Scopus)

Slow brain potentials in a visual-spatial memory task: Topographic distribution and inter-laboratory consistency

Rohrbaugh, J. W., Dunham, D. N., Stewart, P. A., Bauer, L. O., Kuperman, S., O'Connor, S., Porjesz, B. & Begleiter, H., Feb 1997, In : International Journal of Psychophysiology. 25, 2, p. 111-122 12 p.

Research output: Contribution to journalArticle

Brain
Contingent Negative Variation
Reaction Time
Spatial Memory
Retention (Psychology)
1998
104 Citations (Scopus)

Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: Preliminary results from the COGA project

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H., Foroud, T., Goate, A., Litke, A., Chorlian, D. B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L. O., Kuperman, S., O'Connor, S. & Rohrbaugh, J., Sep 1998, In : Alcoholism: Clinical and Experimental Research. 22, 6, p. 1317-1323 7 p.

Research output: Contribution to journalArticle

P300 Event-Related Potentials
Alcoholism
Psychiatry
Alcohols
Sex Distribution
123 Citations (Scopus)
Constriction
Alcohols
Clamping devices
Intravenous Infusions
Oral Administration
125 Citations (Scopus)

Gender differences in alcohol metabolism: Relationship to liver volume and effect of adjusting for body mass

Kwo, P. Y., Ramchandani, V. A., O'Connor, S., Amann, D., Carr, L. G., Sandrasegaran, K., Kopecky, K. K. & Li, T. K., 1998, In : Gastroenterology. 115, 6, p. 1552-1557 6 p.

Research output: Contribution to journalArticle

Alcohols
Liver
Ethanol
Alcoholic Liver Diseases
Intravenous Infusions
137 Citations (Scopus)

Quantitative trait loci analysis of human event-related brain potentials: P3 voltage

Begleiter, H., Porjesz, B., Reich, T., Edenberg, H., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., Bauer, L. O., O'Connor, S., Chorlian, D. B., Li, T. K., Conneally, P. M., Hesselbrock, V., Rice, J. P., Schuckit, M. A. & 4 others, Cloninger, R., Nurnberger, J., Crowe, R. & Bloom, F. E., Apr 1998, In : Electroencephalography and Clinical Neurophysiology/ Evoked Potentials. 108, 3, p. 244-250 7 p.

Research output: Contribution to journalArticle

P300 Event-Related Potentials
Quantitative Trait Loci
Evoked Potentials
Brain
Genetic Loci
1999
121 Citations (Scopus)

A physiologically-based pharmacokinetic (PBPK) model for alcohol facilitates rapid BrAC clamping

Ramchandani, V. A., Bolane, J., Li, T. K. & O'Connor, S., Apr 1999, In : Alcoholism: Clinical and Experimental Research. 23, 4, p. 617-623 7 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Constriction
Alcohols
Ethanol
Clamping devices
51 Citations (Scopus)

A preliminary study of acute responses to clamped alcohol concentration and family history of alcoholism

Ramchandani, V. A., O'Connor, S., Blekher, T., Kareken, D., Morzorati, S., Nurnberger, J. & Li, T. K., 1999, In : Alcoholism: Clinical and Experimental Research. 23, 8, p. 1320-1330 11 p.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Constriction
Brain
Eye movements
14 Citations (Scopus)

A twin study of genetic influences on the acute adaptation of the EEG to alcohol

O'Connor, S., Sorbel, J., Morzorati, S., Li, T. K. & Christian, J. C., Mar 1999, In : Alcoholism: Clinical and Experimental Research. 23, 3, p. 494-501 8 p.

Research output: Contribution to journalArticle

Twin Studies
Electroencephalography
Alcohols
Extremities
Dizygotic Twins
67 Citations (Scopus)

Heritability of event-related brain potentials in families with a history of alcoholism

Almasy, L., Porjesz, B., Blangero, J., Chorlian, D. B., O'Connor, S., Kuperman, S., Rohrbaugh, J., Bauer, L. O., Reich, T., Polich, J. & Begleiter, H., Aug 20 1999, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 88, 4, p. 383-390 8 p.

Research output: Contribution to journalArticle

Evoked Potentials
Alcoholism
Brain
Electrodes
Inborn Genetic Diseases
2000
120 Citations (Scopus)

Frontal P300 decrements, alcohol dependence, and antisocial personality disorder

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J. & Begleiter, H., Jun 2000, In : Biological Psychiatry. 47, 12, p. 1064-1071 8 p.

Research output: Contribution to journalArticle

Antisocial Personality Disorder
Alcoholism
Electrodes
Brain
P300 Event-Related Potentials
36 Citations (Scopus)

PBPK modeling as a basis for achieving a steady of 60 ± 5 mg% within ten minutes

O'Connor, S., Ramchandani, V. A. & Li, T. K., Apr 2000, In : Alcoholism: Clinical and Experimental Research. 24, 4, p. 426-427 2 p.

Research output: Contribution to journalArticle

Central Nervous System Depressants
Biological Models
Breath Tests
Ethanol
78 Citations (Scopus)

The p300 brain potential is reduced in smokers

Anokhin, A. P., Vedeniapin, A. B., Sirevaag, E. J., Bauer, L. O., O'Connor, S., Kuperman, S., Porjesz, B., Reich, T., Begleiter, H., Polich, J. & Rohrbaugh, J. W., 2000, In : Psychopharmacology. 149, 4, p. 409-413 5 p.

Research output: Contribution to journalArticle

Alcoholism
Smoking
P300 Event-Related Potentials
Brain
Substance-Related Disorders
2001
103 Citations (Scopus)

Genetic and environmental influences on alcohol metabolism in humans

Li, T. K., Yin, S. J., Crabb, D., O'Connor, S. & Ramchandani, V. A., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 1, p. 136-144 9 p.

Research output: Contribution to journalArticle

Metabolism
Tolnaftate
Alcohols
Polymorphism
Constriction
50 Citations (Scopus)

Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H., O'Connor, S., Kuperman, S., O'Connor, S. J., Rohrbaugh, J., Bauer, L. O., Foroud, T., Rice, J. P., Reich, T. & Begleiter, H., 2001, In : American Journal of Human Genetics. 68, 1, p. 128-135 8 p.

Research output: Contribution to journalArticle

Evoked Potentials
Semantics
Alcoholism
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 4
87 Citations (Scopus)

P300 event-related potential amplitude as an endophenotype of alcoholism - Evidence from the Collaborative Study on the Genetics of Alcoholism

Hesselbrock, V., Begleiter, H., Porjesz, B., O'Connor, S. & Bauer, L., 2001, In : Journal of Biomedical Science. 8, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

P300 Event-Related Potentials
Endophenotypes
Alcoholism
Alcoholics
Genes
2002
193 Citations (Scopus)

Beta power in the EEG of alcoholics

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Wang, K., Jones, K. A., Bauer, L. O., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T. & Begleiter, H., Oct 15 2002, In : Biological Psychiatry. 52, 8, p. 831-842 12 p.

Research output: Contribution to journalArticle

Alcoholics
Electroencephalography
Alcohols
Scalp
Drinking
89 Citations (Scopus)

Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D. B., Stimus, A. T., Kuperman, S., O'Connor, S., Rohrbaugh, J., Bauer, L. O., Edenberg, H., Goate, A., Rice, J. P. & Reich, T., Oct 2002, In : Biological Psychology. 61, 1-2, p. 229-248 20 p.

Research output: Contribution to journalArticle

Chromosome Mapping
Linkage Disequilibrium
Alcoholism
Electroencephalography
Phenotype
230 Citations (Scopus)

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus

Porjesz, B., Almasy, L., Edenberg, H., Wang, K., Chorlian, D. B., Foroud, T., Goate, A., Rice, J. P., O'Connor, S., Rohrbaugh, J., Kuperman, S., Bauer, L. O., Crowe, R. R., Schuckit, M. A., Hesselbrock, V., Conneally, P. M., Tischfield, J. A., Li, T. K., Reich, T. & Begleiter, H., Mar 19 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 6, p. 3729-3733 5 p.

Research output: Contribution to journalArticle

Aminobutyrates
Linkage Disequilibrium
Automatic Data Processing
Electroencephalography
Brain
10 Citations (Scopus)

Maintaining steady state arterial alcohol levels in rats by using a physiologically based pharmacokinetic model

Morzorati, S., Ramchandani, V. A., Li, T. K. & O'Connor, S., Nov 2002, In : Alcohol. 28, 3, p. 189-195 7 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Rats
alcohol
Alcohols
Wistar Rats
44 Citations (Scopus)

Recent drinking history: Association with family history of alcoholism and the acute response to alcohol during a 60 mg% clamp

Ramchandani, V. A., Flury, L., Morzorati, S., Kareken, D., Blekher, T., Foroud, T., Li, T. K. & O'Connor, S., Nov 2002, In : Journal of Studies on Alcohol. 63, 6, p. 734-744 11 p.

Research output: Contribution to journalArticle

Clamping devices
genealogy
alcoholism
Alcoholism
Drinking
19 Citations (Scopus)

Response of saccadic eye movements to alcohol in African American and non-Hispanic white college students

Blekher, T., Beard, J. D., O'Connor, S., Orr, W. E., Ramchandani, V. A., Miller, K., Yee, R. D. & Li, T. K., 2002, In : Alcoholism: Clinical and Experimental Research. 26, 2, p. 232-238 7 p.

Research output: Contribution to journalArticle

Eye movements
Saccades
African Americans
Alcohols
Students
29 Citations (Scopus)

Saccadic eye movements are associated with a family history of alcoholism at baseline and after exposure to alcohol

Blekher, T., Ramchandani, V. A., Flury, L., Foroud, T., Kareken, D., Yee, R. D., Li, T. K. & O'Connor, S., Oct 2002, In : Alcoholism: Clinical and Experimental Research. 26, 10, p. 1568-1573 6 p.

Research output: Contribution to journalArticle

Eye movements
Saccades
Alcoholism
Alcohols
Placebos
87 Citations (Scopus)

Self-reported subjective perception of intoxication reflects family history of alcoholism when breath alcohol levels are constant

Morzorati, S., Ramchandani, V. A., Flury, L., Li, T. K. & O'Connor, S., Aug 2002, In : Alcoholism: Clinical and Experimental Research. 26, 8, p. 1299-1306 8 p.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Clamping devices
Alcoholic Intoxication
Visual Analog Scale
2003
70 Citations (Scopus)

Theta power in the EEG of alcoholics

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Choi, K., Jones, K. A., Wang, K., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T. & Begleiter, H., Apr 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 4, p. 607-615 9 p.

Research output: Contribution to journalArticle

Alcoholics
Electroencephalography
Analysis of variance (ANOVA)
Parietal Lobe
Alcohols
2004
168 Citations (Scopus)

A family study of alcohol dependence: Coaggregation of multiple disorders in relatives of alcohol-dependent probands

Nurnberger, J., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E. T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A. L., Kuperman, S., Hesselbrock, V. & Porjesz, B., Dec 2004, In : Archives of General Psychiatry. 61, 12, p. 1246-1256 11 p.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Diagnostic and Statistical Manual of Mental Disorders
Substance-Related Disorders
Antisocial Personality Disorder
121 Citations (Scopus)

Alcohol Dehydrogenase Polymorphisms Influence Alcohol-Elimination Rates in a Male Jewish Population

Neumark, Y. D., Friedlander, Y., Durst, R., Leitersdorf, E., Jaffe, D., Ramchandani, V. A., O'Connor, S., Carr, L. G. & Li, T. K., Jan 2004, In : Alcoholism: Clinical and Experimental Research. 28, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

Alcohol Dehydrogenase
Polymorphism
Alcohols
Population
Jews
85 Citations (Scopus)

Alcohol-Related Olfactory Cues Activate the Nucleus Accumbens and Ventral Tegmental Area in High-Risk Drinkers: Preliminary Findings

Kareken, D., Claus, E. D., Sabri, M., Dzemidzic, M., Kosobud, A., Radnovich, A., Hector, D., Ramchandani, V. A., O'Connor, S., Lowe, M. & Li, T. K., Apr 2004, In : Alcoholism: Clinical and Experimental Research. 28, 4, p. 550-557 8 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Nucleus Accumbens
Cues
Odors
Alcohols
108 Citations (Scopus)

Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: Implications for human brain dynamics and cognition

Jones, K. A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Wang, J. C., Dick, D. M., Hinrichs, A., Kwon, J., Rice, J. P., Rohrbaugh, J., Stock, H., Wu, W., Bauer, L. O., Chorlian, D. B., Crowe, R. R., Edenberg, H., Foroud, T., Hesselbrock, V., Kuperman, S. & 7 others, Nurnberger, J., O'Connor, S., Schuckit, M. A., Stimus, A. T., Tischfield, J. A., Reich, T. & Begleiter, H., Jul 2004, In : International Journal of Psychophysiology. 53, 2, p. 75-90 16 p.

Research output: Contribution to journalArticle

Linkage Disequilibrium
Cognition
Single Nucleotide Polymorphism
Electroencephalography
P300 Event-Related Potentials