Sherif Farag

  • 4164 Citations
  • 32 h-Index
1977 …2020

Research output per year

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Publications

2008

Phase II clinical trial of arsenic trioxide with liposomal doxorubicin, vincristine, and dexamethasone in newly diagnosed multiple myeloma

Hofmeister, C. C., Jansak, B., Denlinger, N., Kraut, E. H., Benson, D. M. & Farag, S. S., Aug 1 2008, In : Leukemia Research. 32, 8, p. 1295-1298 4 p.

Research output: Contribution to journalArticle

11 Scopus citations
2009

Natural killer cell activity and killer immunoglobulin-like receptors in hematopoietic stem cell transplantation

Ruggeri, L., Zhang, S. & Farag, S. S., Oct 15 2009, Hematopoietic Stem Cell Transplantation. Bishop, M. (ed.). p. 47-69 23 p. (Cancer Treatment and Research; vol. 144).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma

Farag, S. S., Zhang, S., Jansak, B. S., Wang, X., Kraut, E., Chan, K., Dancey, J. E. & Grever, M. R., Nov 2009, In : Leukemia Research. 33, 11, p. 1475-1480 6 p.

Research output: Contribution to journalArticle

65 Scopus citations
2010
13 Scopus citations

Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma

Wang, X., Sinn, A. L., Pollok, K., Sandusky, G., Zhang, S., Chen, L., Liang, J., Crean, C. D., Suvannasankha, A., Abonour, R., Sidor, C., Bray, M. R. & Farag, S. S., Aug 2010, In : British journal of haematology. 150, 3, p. 313-325 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Quantification of non-specific binding of magnetic micro- and nanoparticles using cell tracking velocimetry: Implication for magnetic cell separation and detection

Chalmers, J. J., Xiong, Y., Jin, X., Shao, M., Tong, X., Farag, S. & Zborowski, M., Apr 15 2010, In : Biotechnology and Bioengineering. 105, 6, p. 1078-1093 16 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

A phase I trial of high-dose clofarabine, etoposide, and cyclophosphamide and autologous peripheral blood stem cell transplantation in patients with primary refractory and relapsed and refractory Non-Hodgkin lymphoma

Srivastava, S., Jones, D., Wood, L. L., Schwartz, J. E., Nelson, R. P., Abonour, R., Secrest, A., Cox, E., Baute, J., Sullivan, C., Kane, K., Robertson, M. J. & Farag, S. S., Jul 1 2011, In : Biology of Blood and Marrow Transplantation. 17, 7, p. 987-994 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Aurora kinase A inhibitor protein kinase inhibitor oncolytic

Zhang, S. & Farag, S., 2011, In : Drugs of the Future. 36, 1, p. 5-15 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Comparison of reduced-intensity hematopoietic cell transplantation with chemotherapy in patients age 60-70 years with acute myelogenous leukemia in first remission

Farag, S. S., Maharry, K., Zhang, M. J., Pérez, W. S., George, S. L., Mrózek, K., DiPersio, J., Bunjes, D. W., Marcucci, G., Baer, M. R., Cairo, M., Copelan, E., Cutler, C. S., Isola, L., Lazarus, H. M., Litzow, M. R., Marks, D. I., Ringdén, O., Rizzieri, D. A., Soiffer, R. & 4 others, Larson, R. A., Tallman, M. S., Bloomfield, C. D. & Weisdorf, D. J., Dec 1 2011, In : Biology of Blood and Marrow Transplantation. 17, 12, p. 1796-1803 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

From cell biology to therapy: ENMD-2076 in the treatment of multiple myeloma

Zhang, S. & Farag, S. S., Jul 1 2011, In : Expert Opinion on Investigational Drugs. 20, 7, p. 1015-1028 14 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect

Benson, D. M., Bakan, C. E., Zhang, S., Collins, S. M., Liang, J., Srivastava, S., Hofmeister, C. C., Efebera, Y., Andre, P., Romagne, F., Bléry, M., Bonnafous, C., Zhang, J., Clever, D., Caligiuri, M. A. & Farag, S. S., Dec 8 2011, In : Blood. 118, 24, p. 6387-6391 5 p.

Research output: Contribution to journalArticle

123 Scopus citations

Phase I trial and pharmacokinetic study of high-dose clofarabine and busulfan and allogeneic stem cell transplantation in adults with high-risk and refractory acute leukemia

Farag, S. S., Wood, L. L., Schwartz, J. E., Srivastava, S., Nelson, R. P., Robertson, M. J., Abonour, R., Secrest, A., Cox, E., Baute, J., Sullivan, C., Kane, K. & Jones, D. R., Apr 2011, In : Leukemia. 25, 4, p. 599-605 7 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: Evidence for lenalidomide-CCI-779 interaction via P-glycoprotein

Hofmeister, C. C., Yang, X., Pichiorri, F., Chen, P., Rozewski, D. M., Johnson, A. J., Lee, S., Liu, Z., Garr, C. L., Hade, E. M., Ji, J., Schaaf, L. J., Benson, D. M., Kraut, E. H., Hicks, W. J., Chan, K. K., Chen, C. S., Farag, S. S., Grever, M. R., Byrd, J. C. & 1 others, Phelps, M. A., Sep 1 2011, In : Journal of Clinical Oncology. 29, 25, p. 3427-3434 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

Prophylaxis with Sirolimus and Tacrolimus ± Antithymocyte Globulin Reduces the Risk of Acute Graft-versus-Host Disease without an Overall Survival Benefit Following Allogeneic Stem Cell Transplantation

Rosenbeck, L. L., Kiel, P. J., Kalsekar, I., Vargo, C., Baute, J., Sullivan, C. K., Wood, L., Abdelqader, S., Schwartz, J., Srivastava, S., Abonour, R., Robertson, M. J., Nelson, R. P., Cornetta, K., Fausel, C. A. & Farag, S. S., Jun 1 2011, In : Biology of Blood and Marrow Transplantation. 17, 6, p. 916-922 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Reduced-intensity allogeneic transplantation provides high event-free and overall survival in patients with advanced indolent B cell malignancies: CALGB 109901

Shea, T., Johnson, J., Westervelt, P., Farag, S., McCarty, J., Bashey, A., Isola, L., Baxter-Lowe, L. A., Kelly, M., Owzar, K. & Linker, C., Sep 1 2011, In : Biology of Blood and Marrow Transplantation. 17, 9, p. 1395-1403 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation for Patients with Hematologic Malignancies Who Relapse following Autologous Transplantation: A Multi-institutional Prospective Study from the Cancer and Leukemia Group B (CALGB trial 100002)

Bashey, A., Owzar, K., Johnson, J. L., Edwards, P. S., Kelly, M., Baxter-Lowe, L. A., Devine, S., Farag, S., Hurd, D., Ball, E., McCarthy, P., Lister, J., Shea, T. C. & Linker, C., Apr 1 2011, In : Biology of Blood and Marrow Transplantation. 17, 4, p. 558-565 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells

Zhang, S., Suvannasankha, A., Crean, C. D., White, V. L., Chen, C. S. & Farag, S. S., Jul 1 2011, In : International Journal of Cancer. 129, 1, p. 204-213 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

The potential role of Aurora kinase inhibitors in haematological malignancies

Farag, S. S., Dec 2011, In : British journal of haematology. 155, 5, p. 561-579 19 p.

Research output: Contribution to journalReview article

43 Scopus citations
2012

Aphase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma

Benson, D. M., Hofmeister, C. C., Padmanabhan, S., Suvannasankha, A., Jagannath, S., Abonour, R., Bakan, C., Andre, P., Efebera, Y., Tiollier, J., Caligiuri, M. A. & Farag, S. S., Nov 22 2012, In : Blood. 120, 22, p. 4324-4333 10 p.

Research output: Contribution to journalArticle

147 Scopus citations

Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis

Broxmeyer, H. E., Hoggatt, J., O'leary, H. A., Mantel, C., Chitteti, B. R., Cooper, S., Messina-Graham, S., Hangoc, G., Farag, S., Rohrabaugh, S. L., Ou, X., Speth, J., Pelus, L. M., Srour, E. F. & Campbell, T. B., Dec 1 2012, In : Nature Medicine. 18, 12, p. 1786-1796 11 p.

Research output: Contribution to journalArticle

129 Scopus citations

T Cell-Depleted Partial Matched Unrelated Donor Transplant for Advanced Myeloid Malignancy: KIR Ligand Mismatch and Outcome

Weisdorf, D., Cooley, S., Devine, S., Fehniger, T. A., DiPersio, J., Anasetti, C., Waller, E. K., Porter, D., Farag, S., Drobyski, W., Defor, T., Haagenson, M., Curtsinger, J. & Miller, J., Jun 1 2012, In : Biology of Blood and Marrow Transplantation. 18, 6, p. 937-943 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2013
16 Scopus citations

Differential stem-and progenitor-cell trafficking by prostaglandin e 2

Hoggatt, J., Mohammad, K. S., Singh, P., Hoggatt, A. F., Chitteti, B. R., Speth, J. M., Hu, P., Poteat, B. A., Stilger, K. N., Ferraro, F., Silberstein, L., Wong, F. K., Farag, S. S., Czader, M., Milne, G. L., Breyer, R. M., Serezani, C. H., Scadden, D. T., Guise, T. A., Srour, E. F. & 1 others, Pelus, L. M., Mar 21 2013, In : Nature. 495, 7441, p. 365-369 5 p.

Research output: Contribution to journalArticle

86 Scopus citations

In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies

Farag, S. S., Srivastava, S., Messina-Graham, S., Schwartz, J., Robertson, M. J., Abonour, R., Cornetta, K., Wood, L., Secrest, A., Strother, R. M., Jones, D. R. & Broxmeyer, H. E., Apr 1 2013, In : Stem cells and development. 22, 7, p. 1007-1015 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Standard pentostatin dose reductions in renal insufficiency are not adequate: Selected patients with steroid-refractory acute graft-versus-host disease

Poi, M. J., Hofmeister, C. C., Johnston, J. S., Edwards, R. B., Jansak, B. S., Lucas, D. M., Farag, S. S., Dalton, J. T., Devine, S. M., Grever, M. R. & Phelps, M. A., Aug 1 2013, In : Clinical Pharmacokinetics. 52, 8, p. 705-712 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
16 Scopus citations
2014

A phase I trial of flavopiridol in relapsed multiple myeloma

Hofmeister, C. C., Poi, M., Bowers, M. A., Zhao, W., Phelps, M. A., Benson, D. M., Kraut, E. H., Farag, S., Efebera, Y. A., Sexton, J., Lin, T. S., Grever, M. & Byrd, J. C., Feb 2014, In : Cancer Chemotherapy and Pharmacology. 73, 2, p. 249-257 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Modelling the sitagliptin effect on dipeptidyl peptidase-4 activity in adults with haematological malignancies after umbilical cord blood haematopoietic cell transplantation

Vélez De Mendizábal, N., Strother, R. M., Farag, S. S., Broxmeyer, H. E., Messina-Graham, S., Chitnis, S. D. & Bies, R. R., Mar 2014, In : Clinical Pharmacokinetics. 53, 3, p. 247-259 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
2015

Cyclophosphamide/fludarabine nonmyeloablative allotransplant for acute myeloid leukemia

Khawaja, M. R., Perkins, S. M., Schwartz, J. E., Robertson, M. J., Kiel, P. J., Sayar, H., Cox, E. A., Vance, G. H., Farag, S. S., Cripe, L. D. & Nelson, R. P., Feb 1 2015, In : American Journal of Hematology. 90, 2, p. 97-99 3 p.

Research output: Contribution to journalArticle

The potential role of PD0332991 (Palbociclib) in the treatment of multiple myeloma

Altenburg, J. D. & Farag, S. S., Feb 1 2015, In : Expert Opinion on Investigational Drugs. 24, 2, p. 261-271 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Cord Blood Hematopoietic Cell Transplantation

Broxmeyer, H. E., Farag, S. S. & Rocha, V., Jan 1 2016, Thomas' Hematopoietic Cell Transplantation: Fifth Edition. Wiley-Blackwell, Vol. 1-2. p. 437-455 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Killer Cell Immunoglobulin-Like Receptor Ligand Mismatching: To Match or Mismatch?

Farag, S. S., Feb 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 2, p. 192-194 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2017

High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation

Farag, S. S., Nelson, R., Cairo, M. S., O'Leary, H. A., Zhang, S., Huntley, C., Delgado, D., Schwartz, J., Zaid, M. A., Abonour, R., Robertson, M. & Broxmeyer, H., 2017, In : Oncotarget. 8, 66, p. 110350-110357 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Immunotherapeutic concepts to target acute myeloid leukemia: Focusing on the role of monoclonal antibodies, hypomethylating agents and the leukemic microenvironment

Gbolahan, O. B., Zeidan, A. M., Stahl, M., Zaid, M. A., Farag, S., Paczesny, S. & Konig, H., Aug 2017, In : International journal of molecular sciences. 18, 8, 1660.

Research output: Contribution to journalReview article

15 Scopus citations

Preliminary efficacy of a brief family intervention to prevent declining quality of life secondary to parental bone marrow transplantation

Fife, B. L., Von Ah, D. M., Spath, M. L., Weaver, M. T., Yang, Z., Stump, T. & Farag, S., Feb 1 2017, In : Bone marrow transplantation. 52, 2, p. 285-291 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Reduced intensity conditioned allograft yields favorable survival for older adults with B-cell acute lymphoblastic leukemia

Rosko, A. E., Wang, H. L., de Lima, M., Sandmaier, B., Khoury, H. J., Artz, A., Brammer, J., Bredeson, C., Farag, S., Kharfan-Dabaja, M., Lazarus, H. M., Marks, D. I., Martino Bufarull, R., McGuirk, J., Mohty, M., Nishihori, T., Nivison-Smith, I., Rashidi, A., Ringden, O., Seftel, M. & 3 others, Weisdorf, D., Bachanova, V. & Saber, W., Jan 1 2017, In : American Journal of Hematology. 92, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
2018
2 Scopus citations
2019

Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia

Lobashevsky, A. L., Krueger-Sersen, M., Britton, R. M., Littrell, C. A., Singh, S., Cui, C. P., Kashi, Z., Martin, R. K., Breman, A. M., Vance, G. H. & Farag, S. S., Apr 2019, In : Human Immunology. 80, 4, p. 257-262 6 p.

Research output: Contribution to journalArticle

2020

Effect of Sirolimus levels between days 11 and 20 after allogeneic stem cell transplantation on the risk of hepatic sinusoidal obstruction syndrome

Agrawal, V., Ranganath, P., Ervin, K. D., Schmidt, C. A., Cox, E. A., Nelson, R. P., Schwartz, J. E., Zaid, M. A., Abonour, R., Robertson, M. J., Brinda, B. J., Griffin, S. P., Thakrar, T. C. & Farag, S. S., 2020, (Accepted/In press) In : Bone marrow transplantation.

Research output: Contribution to journalArticle

KIR B donors improve the outcome for AML patients given reduced intensity conditioning and unrelated donor transplantation

Weisdorf, D., Cooley, S., Wang, T., Trachtenberg, E., Vierra-Green, C., Spellman, S., A. Sees, J., Spahn, A., Vogel, J., Fehniger, T. A., Woolfrey, A. E., Devine, S. M., Ross, M., Waller, E. K., Sobecks, R. M., McGuirk, J., Oran, B., Farag, S. S., Shore, T., Van Besien, K. & 4 others, Marsh, S. G. E., Guethlein, L. A., Parham, P. & Miller, J. S., Feb 25 2020, In : Blood Advances. 4, 4, p. 740-754 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Vaccine and cell-based therapeutic approaches in acute myeloid leukemia

Agrawal, V., Gbolahan, O. B., Stahl, M., Zeidan, A. M., Abu Zaid, M., Farag, S. S. & Konig, H., 2020, In : Current cancer drug targets. 20, 7, p. 473-489 17 p.

Research output: Contribution to journalReview article