Shien-Fong Lin

  • 6414 Citations
  • 42 h-Index
1990 …2020

Research output per year

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Article
2020

Effects of high-frequency biphasic shocks on ventricular vulnerability and defibrillation outcomes through synchronized virtual electrode responses

Chiou, Y. A., Cheng, L. K. & Lin, S. F., May 2020, In : PloS one. 15, 5, e0232529.

Research output: Contribution to journalArticle

Open Access

Effects of ondansetron on apamin-sensitive small conductance calcium-activated potassium currents in pacing-induced failing rabbit hearts

Yin, D., Yang, N., Tian, Z., Wu, A. Z., Xu, D., Chen, M., Kamp, N. J., Wang, Z., Shen, C., Chen, Z., Lin, S. F., Rubart-von der Lohe, M., Chen, P. S. & Everett, T. H., Feb 2020, In : Heart Rhythm. 17, 2, p. 332-340 9 p.

Research output: Contribution to journalArticle

Persistent Proarrhythmic Neural Remodeling Despite Recovery From Premature Ventricular Contraction-Induced Cardiomyopathy

Tan, A. Y., Elharrif, K., Cardona-Guarache, R., Mankad, P., Ayers, O., Joslyn, M., Das, A., Kaszala, K., Lin, S. F., Ellenbogen, K. A., Minisi, A. J. & Huizar, J. F., Jan 7 2020, In : Journal of the American College of Cardiology. 75, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sacubitril/Valsartan Therapy Ameliorates Ventricular Tachyarrhythmia Inducibility in a Rabbit Myocardial Infarction Model

Chang, P. C., Wo, H. T., Lee, H. L., Lin, S. F., Chu, Y., Wen, M. S. & Chou, C. C., 2020, (Accepted/In press) In : Journal of Cardiac Failure.

Research output: Contribution to journalArticle

1 Scopus citations

Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG)

Kusayama, T., Wong, J., Liu, X., He, W., Doytchinova, A., Robinson, E. A., Adams, D. E., Chen, L. S., Lin, S. F., Davoren, K., Victor, R. G., Cai, C., Dai, M. Y., Tian, Y., Zhang, P., Ernst, D., Rho, R. H., Chen, M., Cha, Y. M., Walega, D. R. & 2 others, Everett, T. H. & Chen, P. S., May 1 2020, In : Nature protocols. 15, 5, p. 1853-1877 25 p.

Research output: Contribution to journalArticle

Skin sympathetic nerve activity as a biomarker for syncopal episodes during a tilt table test

Kumar, A., Wright, K., Uceda, D. E., Vasallo, P. A., Rabin, P. L., Adams, D., Wong, J., Das, M., Lin, S. F., Chen, P. S. & Everett, T. H., May 2020, In : Heart Rhythm. 17, 5, p. 804-812 9 p.

Research output: Contribution to journalArticle

Ventricular divergence correlates with epicardial wavebreaks and predicts ventricular arrhythmia in isolated rabbit hearts during therapeutic hypothermia

Hsieh, Y. C., Hsieh, W. H., Li, C. H., Liao, Y. C., Lin, J. C., Weng, C. J., Lo, M. T., Tuan, T. C., Lin, S. F., Yeh, H. I., Huang, J. L., Haugan, K., Larsen, B. D., Lin, Y. J., Lin, W. W., Wu, T. J. & Chen, S. A., 2020, In : PloS one. 15, 2, e0228818.

Research output: Contribution to journalArticle

Open Access

Wearable piezoelectric-based system for continuous beat-to-beat blood pressure measurement

Wang, T. W. & Lin, S. F., Feb 1 2020, In : Sensors (Switzerland). 20, 3, 851.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12

Pan, Z., Ai, T., Chang, P. C., Liu, Y., Liu, J., Maruyama, M., Homsi, M., Fishbein, M. C., Rubart, M., Lin, S. F., Xiao, D., Chen, H., Chen, P. S., Shou, W. & Li, B. Y., Feb 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 2, p. H371-H379

Research output: Contribution to journalArticle

1 Scopus citations

Cardiac Influence of Repetitive Transcranial Magnetic Stimulation in Small Animals

Wang, T. W., Sung, Y. L. & Lin, S. F., Jan 1 2019, (Accepted/In press) In : IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology.

Research output: Contribution to journalArticle

LCZ696 therapy reduces ventricular tachyarrhythmia inducibility in a myocardial infarction-induced heart failure rat model

Chang, P. C., Lin, S. F., Chu, Y., Wo, H. T., Lee, H. L., Huang, Y. C., Wen, M. S. & Chou, C. C., Jan 1 2019, In : Cardiovascular Therapeutics. 2019, 6032631.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Remote magnetic control of autophagy in mouse b-lymphoma cells with iron oxide nanoparticles

Lin, Y. R., Chan, C. H., Lee, H. T., Cheng, S. J., Yang, J. W., Chang, S. J., Lin, S. F. & Chen, G. Y., Apr 2019, In : Nanomaterials. 9, 4, 551.

Research output: Contribution to journalArticle

Open Access

The Development of Controllable Magnetic Driven Microphysiological System

Yang, J. W., Chen, Y. W., Ho, P. Y., Jiang, L., Hsieh, K. Y., Cheng, S. J., Lin, K. C., Lu, H. E., Chiu, H. Y., Lin, S. F. & Chen, G. Y., Nov 7 2019, In : Frontiers in Cell and Developmental Biology. 7, 275.

Research output: Contribution to journalArticle

Open Access
2018

Antiarrhythmic effects of stimulating the left dorsal branch of the thoracic nerve in a canine model of paroxysmal atrial tachyarrhythmias

Zhao, Y., Yuan, Y., Tsai, W. C., Jiang, Z., Tian, Z. P., Shen, C., Lin, S. F., Fishbein, M. C., Everett, T. H., Chen, Z. & Chen, P. S., Aug 2018, In : Heart Rhythm. 15, 8, p. 1242-1251 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Concomitant SK current activation and sodium current inhibition cause J wave syndrome

Chen, M., Xu, D. Z., Wu, A. Z., Guo, S., Wan, J., Yin, D., Lin, S. F., Chen, Z., Rubart-von der Lohe, M., Everett, T. H., Qu, Z., Weiss, J. N. & Chen, P. S., Nov 15 2018, In : JCI Insight. 3, 22

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Effects of long-term exercise on arrhythmogenesis in aged hypertensive rats

Sung, Y. L., Wu, C. E., Syu, J. Y., Kuo, T. B. J., Li, J. Y., Chen, C. W., Weng, C. H., Hsu, W. H., Chen, S. A., Hu, Y. F. & Lin, S. F., Nov 1 2018, In : Computers in Biology and Medicine. 102, p. 390-395 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of Stellate Ganglion Cryoablation on Subcutaneous Nerve Activity and Atrial Tachyarrhythmias in a Canine Model of Pacing-Induced Heart Failure

Shelton, R. S., Ogawa, M., Lin, H., Shen, C., Wong, J., Lin, S. F., Chen, P. S. & Everett, T. H., May 2018, In : JACC: Clinical Electrophysiology. 4, 5, p. 686-695 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of Vagal Nerve Stimulation on Ganglionated Plexi Nerve Activity and Ventricular Rate in Ambulatory Dogs With Persistent Atrial Fibrillation

Jiang, Z., Zhao, Y., Tsai, W. C., Yuan, Y., Chinda, K., Tan, J., Onkka, P., Shen, C., Chen, L. S., Fishbein, M. C., Lin, S. F., Chen, P. S. & Everett, T. H., Aug 2018, In : JACC: Clinical Electrophysiology. 4, 8, p. 1106-1114 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Electrical coupling between ventricular myocytes and myofibroblasts in the infarcted mouse heart

Rubart, M., Tao, W., Lu, X. L., Conway, S. J., Reuter, S. P., Lin, S. F. & Soonpaa, M. H., Mar 1 2018, In : Cardiovascular research. 114, 3, p. 389-400 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Interleukin-17 enhances cardiac ventricular remodeling via activating MAPK pathway in ischemic heart failure

Chang, S. L., Hsiao, Y. W., Tsai, Y. N., Lin, S. F., Liu, S. H., Lin, Y. J., Lo, L. W., Chung, F. P., Chao, T. F., Hu, Y. F., Tuan, T. C., Liao, J. N., Hsieh, Y. C., Wu, T. J., Higa, S. & Chen, S. A., Sep 2018, In : Journal of Molecular and Cellular Cardiology. 122, p. 69-79 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Long-term intermittent high-amplitude subcutaneous nerve stimulation reduces sympathetic tone in ambulatory dogs

Yuan, Y., Jiang, Z., Zhao, Y., Tsai, W. C., Patel, J., Chen, L. S., Shen, C., Lin, S. F., Chen, H. S. V., Everett, T. H., Fishbein, M. C., Chen, Z. & Chen, P. S., Mar 2018, In : Heart Rhythm. 15, 3, p. 451-459 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Methodological considerations in calculating heart rate variability based on wearable device heart rate samples

Chen, H. K., Hu, Y. F. & Lin, S. F., Nov 1 2018, In : Computers in Biology and Medicine. 102, p. 396-401 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Noninvasive glucose monitoring with a contact lens and smartphone

Lin, Y. R., Hung, C. C., Chiu, H. Y., Chang, B. H., Li, B. R., Cheng, S. J., Yang, J. W., Lin, S. F. & Chen, G. Y., Oct 2018, In : Sensors (Switzerland). 18, 10, 3208.

Research output: Contribution to journalArticle

8 Scopus citations

Ondansetron blocks wild-type and p.F503l variant small-conductance Ca2+-activated K+ channels

Ko, J. S., Guo, S., Hassel, J., Celestino-Soper, P., Lynnes, T. C., Tisdale, J. E., Zheng, J. J., Taylor, S. E., Foroud, T., Murray, M. D., Kovacs, R. J., Li, X., Lin, S. F., Chen, Z., Vatta, M., Chen, P. S. & Rubart, M., Aug 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 2, p. H375-H388

Research output: Contribution to journalArticle

6 Scopus citations

Oscillatory behavior of P wave duration and PR interval in experimental congestive heart failure: A preliminary study

Piccirillo, G., Magrì, D., D'Alessandro, G., Fiorucci, C., Moscucci, F., Iorio, C. D., Mastropietri, F., Parrotta, I., Ogawa, M., Lin, S. F. & Chen, P. S., Jan 1 2018, In : Physiological Measurement. 39, 3, 035010.

Research output: Contribution to journalArticle

Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade de Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model

Chang, P. C., Lu, Y. Y., Lee, H. L., Lin, S. F., Chu, Y., Wen, M. S. & Chou, C. C., Aug 1 2018, In : Journal of cardiovascular pharmacology. 72, 2, p. 97-105 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phospholamban regulates nuclear Ca2+ stores and inositol 1,4,5-trisphosphate mediated nuclear Ca2+ cycling in cardiomyocytes

Chen, M., Xu, D., Wu, A. Z., Kranias, E., Lin, S. F., Chen, P. S. & Chen, Z., Oct 2018, In : Journal of Molecular and Cellular Cardiology. 123, p. 185-197 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Role of apamin-sensitive small conductance calcium-activated potassium currents in long-term cardiac memory in rabbits

Yin, D., Chen, M., Yang, N., Wu, A. Z., Xu, D., Tsai, W. C., Yuan, Y., Tian, Z., Chan, Y. H., Shen, C., Chen, Z., Lin, S. F., Weiss, J. N., Chen, P. S. & Everett, T. H., May 2018, In : Heart Rhythm. 15, 5, p. 761-769 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sex-specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles

Chen, M., Yin, D., Guo, S., Xu, D. Z., Wang, Z., Chen, Z., Rubart-von der Lohe, M., Lin, S. F., Everett, T. H., Weiss, J. N. & Chen, P. S., Sep 15 2018, In : Journal of Physiology. 596, 18, p. 4299-4322 24 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Effects of renal sympathetic denervation on the stellate ganglion and brain stem in dogs

Tsai, W. C., Chan, Y. H., Chinda, K., Chen, Z., Patel, J., Shen, C., Zhao, Y., Jiang, Z., Yuan, Y., Ye, M., Chen, L. S., Riley, A. A., Persohn, S. A., Territo, P. R., Everett, T. H., Lin, S. F., Vinters, H. V., Fishbein, M. C. & Chen, P. S., Feb 1 2017, In : Heart Rhythm. 14, 2, p. 255-262 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Left cervical vagal nerve stimulation reduces skin sympathetic nerve activity in patients with drug resistant epilepsy

Yuan, Y., Hassel, J. L., Doytchinova, A., Adams, D., Wright, K. C., Meshberger, C., Chen, L. S., Guerra, M. P., Shen, C., Lin, S. F., Everett, T. H., Salanova, V. & Chen, P. S., Dec 2017, In : Heart Rhythm. 14, 12, p. 1771-1778 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Role of apamin-sensitive calcium-activated small-conductance potassium currents on the mechanisms of ventricular fibrillation in pacing-induced failing rabbit hearts

Yin, D., Hsieh, Y. C., Tsai, W. C., Zhi-Yang Wu, A., Jiang, Z., Chan, Y. H., Xu, D., Yang, N., Shen, C., Chen, Z., Lin, S. F., Chen, P. S. & Everett, T. H., Feb 1 2017, In : Circulation: Arrhythmia and Electrophysiology. 10, 2, e004434.

Research output: Contribution to journalArticle

4 Scopus citations

Roles of impaired intracellular calcium cycling in arrhythmogenicity of diabetic mouse model

Chou, C. C., Ho, C. T., Lee, H. L., Chu, Y., Yen, T. H., Wen, M. S., Lin, S. F., Lee, C. H. & Chang, P. C., Oct 2017, In : PACE - Pacing and Clinical Electrophysiology. 40, 10, p. 1087-1095 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Simultaneous noninvasive recording of skin sympathetic nerve activity and electrocardiogram

Doytchinova, A., Hassel, J. L., Yuan, Y., Lin, H., Yin, D., Adams, D., Straka, S., Wright, K., Smith, K., Wagner, D., Shen, C., Salanova, V., Meshberger, C., Chen, L. S., Kincaid, J. C., Coffey, A. C., Wu, G., Li, Y., Kovacs, R. J., Everett, T. H. & 4 others, Victor, R., Cha, Y. M., Lin, S. F. & Chen, P. S., Jan 1 2017, In : Heart Rhythm. 14, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Simultaneous recordings of intrinsic cardiac nerve activity and skin sympathetic nerve activity from human patients during the postoperative period

Shen, M. J., Coffey, A. C., Straka, S., Adams, D. E., Wagner, D. B., Kovacs, R. J., Clark, M., Shen, C., Chen, L. S., Everett, T. H., Lin, S. F. & Chen, P. S., Nov 2017, In : Heart Rhythm. 14, 11, p. 1587-1593 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Skin sympathetic nerve activity precedes the onset and termination of paroxysmal atrial tachycardia and fibrillation

Uradu, A., Wan, J., Doytchinova, A., Wright, K. C., Lin, A. Y. T., Chen, L. S., Shen, C., Lin, S. F., Everett, T. H. & Chen, P. S., Jul 2017, In : Heart Rhythm. 14, 7, p. 964-971 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
2016

Ganglionated plexi and ligament of Marshall ablation reduces atrial vulnerability and causes stellate ganglion remodeling in ambulatory dogs

Zhao, Y., Jiang, Z., Tsai, W. C., Yuan, Y., Chinda, K., Choi, E. K., Fishbein, M. C., Lin, S. F., Chen, P. S. & Everett, T. H., Oct 1 2016, In : Heart Rhythm. 13, 10, p. 2083-2090 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Gap junction modifier rotigaptide decreases the susceptibility to ventricular arrhythmia by enhancing conduction velocity and suppressing discordant alternans during therapeutic hypothermia in isolated rabbit hearts

Hsieh, Y. C., Lin, J. C., Hung, C. Y., Li, C. H., Lin, S. F., Yeh, H. I., Huang, J. L., Lo, C. P., Haugan, K., Larsen, B. D. & Wu, T. J., Jan 1 2016, In : Heart Rhythm. 13, 1, p. 251-261 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Intermittent left cervical vagal nerve stimulation damages the stellate ganglia and reduces the ventricular rate during sustained atrial fibrillation in ambulatory dogs

Chinda, K., Tsai, W. C., Chan, Y. H., Lin, A. Y. T., Patel, J., Zhao, Y., Tan, A. Y., Shen, M. J., Lin, H., Shen, C., Chattipakorn, N., Rubart-Von Der Lohe, M., Chen, L. S., Fishbein, M. C., Lin, S. F., Chen, Z. & Chen, P. S., Mar 1 2016, In : Heart Rhythm. 13, 3, p. 771-780 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Phospholamban is concentrated in the nuclear envelope of cardiomyocytes and involved in perinuclear/nuclear calcium handling

Wu, A. Z., Xu, D., Yang, N., Lin, S. F., Chen, P. S., Cala, S. E. & Chen, Z., Nov 1 2016, In : Journal of Molecular and Cellular Cardiology. 100, p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pleiotropic Effects of Myocardial MMP-9 Inhibition to Prevent Ventricular Arrhythmia

Weng, C. H., Chung, F. P., Chen, Y. C., Lin, S-F., Huang, P. H., Kuo, T. B. J., Hsu, W. H., Su, W. C., Sung, Y. L., Lin, Y. J., Chang, S. L., Lo, L. W., Yeh, H. I., Chen, Y. J., Hong, Y. R., Chen, S. A. & Hu, Y. F., Dec 14 2016, In : Scientific Reports. 6, 38894.

Research output: Contribution to journalArticle

6 Scopus citations

Proarrhythmic risk and determinants of cardiac autonomic dysfunction in collagen-induced arthritis rats

Lin, T. T., Sung, Y. L., Wu, C. E., Zhang, H., Liu, Y. B. & Lin, S. F., Nov 29 2016, In : BMC Musculoskeletal Disorders. 17, 1, p. 1-8 8 p., 491.

Research output: Contribution to journalArticle

1 Scopus citations

Small conductance calcium-activated potassium current and the mechanism of atrial arrhythmia in mice with dysfunctional melanocyte-like cells

Tsai, W. C., Chan, Y. H., Hsueh, C. H., Everett, T. H., Chang, P. C., Choi, E. K., Olaopa, M. A., Lin, S. F., Shen, C., Kudela, M. A., Rubart-Von Der Lohe, M., Chen, Z., Jadiya, P., Tomar, D., Luvison, E., Anzalone, N., Patel, V. V. & Chen, P. S., Jul 1 2016, In : Heart Rhythm. 13, 7, p. 1527-1535 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Subcutaneous nerve activity and mechanisms of sudden death in a rat model of chronic kidney disease

Zhao, Y., Chen, N. X., Shirazi, J. T., Shen, C., Lin, S. F., Fishbein, M. C., Moe, S. M. & Chen, P. S., May 1 2016, In : Heart Rhythm. 13, 5, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Accelerating sino-atrium computer simulations with graphic processing units

Zhang, H., Xiao, Z. & Lin, S. F., Jan 1 2015, In : Bio-Medical Materials and Engineering. 26, p. S739-S746

Research output: Contribution to journalArticle

Acute reversal of phospholamban inhibition facilitates the rhythmic whole-cell propagating calcium waves in isolated ventricular myocytes

Chan, Y. H., Tsai, W. C., Song, Z., Ko, C. Y., Qu, Z., Weiss, J. N., Lin, S. F., Chen, P. S., Jones, L. R. & Chen, Z., Mar 1 2015, In : Journal of Molecular and Cellular Cardiology. 80, p. 126-135 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Age-dependent alterations of voltage-gated Na+ channel isoforms in rat sinoatrial node

Huang, X., Du, Y., Yang, P., Lin, S-F., Xi, Y., Yang, Z. & Ma, A., Dec 1 2015, In : Mechanisms of Ageing and Development. 152, p. 80-90 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cervical vagal nerve stimulation activates the stellate ganglion in ambulatory dogs

Rhee, K. S., Hsueh, C. H., Hellyer, J. A., Park, H. W., Lee, Y. S., Garlie, J., Onkka, P., Doytchinova, A. T., Garner, J. B., Pate, J., Chen, L. S., Fishbein, M. C., Everett, T., Lin, S. F. & Chen, P. S., Mar 1 2015, In : Korean Circulation Journal. 45, 2, p. 149-157 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Estimating sympathetic tone by recording subcutaneous nerve activity in ambulatory dogs

Robinson, E. A., Rhee, K. S., Doytchinova, A., Kumar, M., Shelton, R., Jiang, Z., Kamp, N. J., Adams, D., Wagner, D., Shen, C., Chen, L. S., Everett, T. H., Fishbein, M. C., Lin, S. F. & Chen, P. S., Jan 1 2015, In : Journal of cardiovascular electrophysiology. 26, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Neuronally released vasoactive intestinal polypeptide alters atrial electrophysiological properties and may promote atrial fibrillation

Xi, Y., James Chao, Z. Y., Yan, W., Abbasi, S., Yin, X., Mathuria, N., Patel, M., Fan, C., Sun, J., Wu, G., Wang, S., Elayda, M., Gao, L., Wehrens, X. H. T., Lin, S. F. & Cheng, J., Jun 1 2015, In : Heart Rhythm. 12, 6, p. 1352-1361 10 p.

Research output: Contribution to journalArticle

1 Scopus citations